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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

C8orf44-SGK3 Gene

protein-coding   GIFtS: 31
GCID: GC08P067579

C8orf44-SGK3 Readthrough

  Search for C8orf44-SGK3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
C8orf44-SGK3 Readthrough1 2     CISK3
Cytokine-Independent Survival Kinase2 3     SGKL3
Serum/Glucocorticoid-Regulated Kinase 32 3     Serum/Glucocorticoid-Regulated Kinase-Like3
EC 2.7.11.13 8     EC 2.7.118
Serine/Threonine-Protein Kinase Sgk32     

External Ids:    HGNC: 483541   Entrez Gene: 1005331052   Ensembl: ENSG000002700247   UniProtKB: Q96BR13   

Export aliases for C8orf44-SGK3 gene to outside databases

Previous GC identifer: GC08U901547


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for C8orf44-SGK3 Gene:
This locus represents naturally occurring read-through transcription between the neighboring putative
uncharacterized protein C8orf44 (GeneID 56260) and serine/threonine-protein kinase Sgk3 (GeneID 23678) genes on
chromosome 8. The read-through transcript produces a protein that shares sequence identity with the downstream
gene product. (provided by RefSeq, Feb 2011)

GeneCards Summary for C8orf44-SGK3 Gene: 
C8orf44-SGK3 (C8orf44-SGK3 readthrough) is a protein-coding gene. GO annotations related to this gene include protein serine/threonine kinase activity and phosphatidylinositol binding. An important paralog of this gene is RPS6KA6.

UniProtKB/Swiss-Prot: SGK3_HUMAN, Q96BR1
Function: Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels,
membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na(+) channels:
SCNN1A/ENAC and SCN5A, K(+) channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial Ca(2+) channels: TRPV5
and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na(+)/dicarboxylate cotransporter:
SLC13A2/NADC1, Na(+)-dependent phosphate cotransporter: SLC34A2/NAPI-2B, amino acid transporters: SLC1A5/ASCT2
and SLC6A19, glutamate transporters: SLC1A3/EAAT1, SLC1A6/EAAT4 and SLC1A7/EAAT5, glutamate receptors:
GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase. Plays a role in the
regulation of renal tubular phosphate transport and bone density. Phosphorylates NEDD4L and GSK3B. Positively
regulates ER transcription activity through phosphorylation of FLII. Negatively regulates the function of
ITCH/AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for C8orf44-SGK3
         Other transcription factors

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Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C8orf44-SGK3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Ensembl cytogenetic band:  8q13.1   HGNC cytogenetic band: 8q13.1

C8orf44-SGK3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C8orf44-SGK3 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P067579:  view genomic region     (about GC identifiers)

Start:
67,579,787 bp from pter      End:
67,774,257 bp from pter
Size:
194,471 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SGK3_HUMAN, Q96BR1 (See protein sequence)
Recommended Name: Serine/threonine-protein kinase Sgk3  
Size: 496 amino acids; 57108 Da
Subunit: Interacts with GSK3B and FLII. Interacts with PDPK1 in a phosphorylation-dependent manner
Subcellular location: Cytoplasmic vesicle (By similarity). Early endosome. Recycling endosome. Note=Endosomal
localization is a prerequisite for complete kinase activity. It is essential for its co-localization with the
kinase responsible for phosphorylating Ser-486 thus allowing PDPK1 phosphorylation of Thr-320 resulting in
complete activation of SGK3. Localized in vesicle-like structures and in the early endosome. Co-localizes with
SLC9A3/NHE3 in the recycling endosomes
Sequence caution: Sequence=AAF12758.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A8K5W3 B3KQC2 Q9P1Q7 Q9UKG5
Alternative splicing: 2 isoforms:  Q96BR1-1   Q96BR1-2   

Explore the universe of human proteins at neXtProt for C8orf44-SGK3: NX_Q96BR1

Explore proteomics data for C8orf44-SGK3 at MOPED 

Post-translational modifications:

  • UniProtKB: Activated by phosphorylation on Ser-486 by an unknown kinase (may be mTORC2 but not confirmed), transforming it
    into a substrate for PDPK1 which then phosphorylates it on Thr-320
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96BR1

  • 4/12 DME Specific Peptides for C8orf44-SGK3 (Q96BR1) (see all 12)
     FYAAEIA  VNGGELF  RDLKPEN  DFGLCKE 

    C8orf44-SGK3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    C8orf44-SGK3 Protein Expression
    REFSEQ proteins: NP_001191102.1  
    ENSEMBL proteins: 
     ENSP00000429022  
    Reactome Protein details: Q96BR1
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    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005769early endosome IEA--
    GO:0005829cytosol TAS--
    GO:0016023cytoplasmic membrane-bounded vesicle IEA--
    GO:0055037recycling endosome IEA--

    C8orf44-SGK3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/8 InterPro protein domains (see all 8):
     IPR017441 Protein_kinase_ATP_BS
     IPR002290 Ser/Thr_dual-sp_kinase_dom
     IPR001683 Phox
     IPR000961 AGC-kinase_C
     IPR011009 Kinase-like_dom

    Graphical View of Domain Structure for InterPro Entry Q96BR1

    ProtoNet protein and cluster: Q96BR1

    2 Blocks protein domains:
    IPB000961 Protein kinase C-terminal domain
    IPB001683 Phox-like


    UniProtKB/Swiss-Prot: SGK3_HUMAN, Q96BR1
    Similarity: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family
    Similarity: Contains 1 AGC-kinase C-terminal domain
    Similarity: Contains 1 protein kinase domain
    Similarity: Contains 1 PX (phox homology) domain


    C8orf44-SGK3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SGK3_HUMAN, Q96BR1
    Function: Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels,
    membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na(+) channels:
    SCNN1A/ENAC and SCN5A, K(+) channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial Ca(2+) channels: TRPV5
    and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na(+)/dicarboxylate cotransporter:
    SLC13A2/NADC1, Na(+)-dependent phosphate cotransporter: SLC34A2/NAPI-2B, amino acid transporters: SLC1A5/ASCT2
    and SLC6A19, glutamate transporters: SLC1A3/EAAT1, SLC1A6/EAAT4 and SLC1A7/EAAT5, glutamate receptors:
    GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase. Plays a role in the
    regulation of renal tubular phosphate transport and bone density. Phosphorylates NEDD4L and GSK3B. Positively
    regulates ER transcription activity through phosphorylation of FLII. Negatively regulates the function of
    ITCH/AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein
    Enzyme regulation: Two specific sites, one in the kinase domain (Thr-320) and the other in the C-terminal
    regulatory region (Ser-486), need to be phosphorylated for its full activation
    Induction: Induced by estrogen/ER in breast cancer cells

         Enzyme Numbers (IUBMB): EC 2.7.11.11 2 EC 2.7.112

         Gene Ontology (GO): 5/11 molecular function terms (GO ID links to tree view) (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004672protein kinase activity TAS10548550
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0004713protein tyrosine kinase activity ----
    GO:0005246calcium channel regulator activity TAS16460280
    GO:0005515protein binding IPI16888620
         
    C8orf44-SGK3 for ontologies           About GeneDecksing


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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for C8orf44-SGK3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Insulin Signaling
    Insulin Signaling
    2PI3K-Akt signaling pathway
    PI3K-Akt signaling pathway

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for C8orf44-SGK3
        Insulin Signaling

    3        Reactome Pathways for C8orf44-SGK3
        Transmembrane transport of small molecules
    Stimuli-sensing channels
    Ion channel transport


    1         Kegg Pathway  (Kegg details for C8orf44-SGK3):
        PI3K-Akt signaling pathway


    C8orf44-SGK3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C8orf44-SGK3

    5/7 Interacting proteins for C8orf44-SGK3 (Q96BR12, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ITCHQ96J022, 3MINT-2881316 MINT-2881371 MINT-2879884 MINT-2881283 MINT-2881346 I2D: score=1 
    PDK1Q151182, 3MINT-2881442 MINT-2881402 I2D: score=1 
    GSK3BP498413I2D: score=2 
    ESR1P033723I2D: score=1 
    GSK3AP498403I2D: score=1 
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001558regulation of cell growth TAS--
    GO:0006468protein phosphorylation TAS10548550
    GO:0006950response to stress TAS10548550
    GO:0007154cell communication IEA--
    GO:0030334regulation of cell migration TAS--

    C8orf44-SGK3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for C8orf44-SGK3 (SGK3)

    Search CenterWatch for drugs/clinical trials and news about C8orf44-SGK3 / SGK3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for C8orf44-SGK3 gene: 
    NM_001204173.1  

    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000520044 ENST00000519289
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    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    C8orf44-SGK3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    C8orf44-SGK3 Expression
    About this image


    See C8orf44-SGK3 Protein Expression from SPIRE MOPED and PaxDB

    UniProtKB/Swiss-Prot: SGK3_HUMAN, Q96BR1
    Tissue specificity: Expressed in most tissues with highest levels in pancreas, kidney liver, heart and brain and
    lower levels in lung, placenta and skeletal muscle. Expression is higher in ER-positive breast tumors than
    ER-negative breast tumors

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for C8orf44-SGK3 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sgk31 serum/glucocorticoid regulated kinase 3 90.39(n)
    96.77(a)
      170755  NM_001037759.1  NP_001032848.1 
    chicken
    (Gallus gallus)
    Aves SGK31 serum/glucocorticoid regulated kinase family, member more 84.19(n)
    93.87(a)
      420167  NM_001030940.1  NP_001026111.1 
    lizard
    (Anolis carolinensis)
    Reptilia SGK36
    Uncharacterized protein
    92(a)
    1 → many
    4(30940678-31007924)
    zebrafish
    (Danio rerio)
    Actinopterygii sgk31 serum/glucocorticoid regulated kinase family, member more 72.22(n)
    79.01(a)
      564523  NM_001110467.1  NP_001103937.1 
    worm
    (Caenorhabditis elegans)
    Secernentea sgk-16
    Serine/threonine-protein kinase sgk-1
    45(a)
    1 → many
    X(16254840-16262129)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YPK16
    YPK26
    Serine/threonine protein kinase that phosphorylate...
    Protein kinase with similarity to serine/threonine...
    27(a)
    27(a)
    many ↔ many
    many ↔ many
    XI(205707-207749)
    XIII(473420-475453)


    ENSEMBL Gene Tree for C8orf44-SGK3 (if available)
    TreeFam Gene Tree for C8orf44-SGK3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for C8orf44-SGK3 gene
    SGK31 2  RPS6KA62  AKT12  RPS6KB12  RPS6KA12  SGK22  RPS6KA52  AKT32  
    RPS6KA42  SGK12  RPS6KB22  RPS6KA22  RPS6KA32  AKT22  

    C8orf44-SGK3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/505 SNPs in C8orf44-SGK3 are shown (see all 505)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1913174001,2
    --67593955(+) CCCCAA/GTTCAA 1 -- int10--------
    rs752416721,2
    C--67594004(+) ACAGGC/TGCCTG 1 -- int10--------
    rs767073681,2
    C--67594005(+) CAGGTC/GCCTGA 1 -- int10--------
    rs1138905461,2
    C,F--67594623(+) TGCCTG/ATTTCA 1 -- int13Minor allele frequency- A:0.04CSA WA 120
    rs1824563651,2
    --67594629(+) TTTCAC/TCATGA 1 -- int10--------
    rs1868229371,2
    --67594675(+) TGAACA/GTACAG 1 -- int10--------
    rs772243631,2
    C,F--67594725(+) TGTTCA/GTGTTT 1 -- int11Minor allele frequency- G:0.02NA 120
    rs78186331,2
    C,F,A,H--67594777(+) CCTCCT/CTGTGA 1 -- int113Minor allele frequency- C:0.07NS EA NA WA 1348
    rs1435013021,2
    --67594779(+) TCCTTC/GTGATT 1 -- int10--------
    rs1896788081,2
    --67595068(+) CACTTA/GCTGCC 1 -- int10--------

    HapMap Linkage Disequilibrium report for C8orf44-SGK3 (67579787 - 67774257 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for C8orf44-SGK3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2671255CNV Deletion23128226
    esv2675141CNV Deletion23128226
    esv2062022CNV Deletion18987734
    nsv6239CNV Insertion18451855
    esv2466698CNV Insertion19546169
    esv1319586CNV Insertion17803354
    nsv6238CNV Insertion18451855
    nsv831346CNV Loss17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for C8orf44-SGK3 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with C8orf44-SGK3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Patterns of somatic mutation in human cancer genomes. (PubMed id 17344846)1, 2 Greenman C.... Stratton M.R. (2007)
    2. Sgk kinases and their role in epithelial transport. (PubMed id 16460280)1, 2 Loffing J....Staub O. (2006)
    3. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)1, 2 Sjoeblom T.... Velculescu V.E. (2006)
    4. Role of the Phox homology domain and phosphorylation in activation of serum and glucocorticoid-regulated kinase-3. (PubMed id 16790420)1, 2 Tessier M. and Woodgett J.R. (2006)
    5. CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4. (PubMed id 16888620)1, 2 Slagsvold T....Stenmark H. (2006)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. K(+) channel activation by all three isoforms of serum- and glucocorticoid-dependent protein kinase SGK. (PubMed id 12397388)1, 2 Gamper N.... Lang F. (2002)
    9. Cloning and mapping of a novel human Serum/Glucocorticoid regulated kinase-like gene, SGKL, to chromosome 8q12.3-q13.1. (PubMed id 10585774)1, 2 Dai F.... Zhao S. (1999)
    10. Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase. (PubMed id 10548550)1, 2 Kobayashi T.... Cohen P. (1999)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 100533105 HGNC: 48354 Ensembl:ENSG00000270024 euGenes: HUgn100533105 ECgene: C8orf44-SGK3 Kegg: 100533105
    H-InvDB: C8orf44-SGK3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for C8orf44-SGK3 gene:
    Search GeneIP for patents involving C8orf44-SGK3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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