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Aliases for C8orf44 Gene

Aliases for C8orf44 Gene

  • Chromosome 8 Open Reading Frame 44 2 3 5

External Ids for C8orf44 Gene

Previous GeneCards Identifiers for C8orf44 Gene

  • GC08P067743
  • GC08P067588
  • GC08P063080

Summaries for C8orf44 Gene

GeneCards Summary for C8orf44 Gene

C8orf44 (Chromosome 8 Open Reading Frame 44) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C8orf44 Gene

Genomics for C8orf44 Gene

Regulatory Elements for C8orf44 Gene

Enhancers for C8orf44 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F066663 0.7 ENCODE 15.9 -1.4 -1355 6.1 HDGF PKNOX1 ARNT CREB3L1 MLX ARID4B SIN3A DMAP1 YY1 ZNF207 ARFGEF1 C8orf44 MYBL1 C8orf46 VCPIP1 ENSG00000201365
GH08F065799 0.9 Ensembl ENCODE 14.6 -867.3 -867305 2.0 ATF1 ARID4B SIN3A FEZF1 ZNF48 YY1 RARA ZNF335 GLIS2 SCRT2 MTFR1 C8orf44 LINC01299 ENSG00000272010 GC08M065824 GC08P065773
GH08F067061 0.6 ENCODE 14 +395.9 395930 5.4 HDGF PKNOX1 CREB3L1 MLX WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 C8orf44 ARFGEF1 TCF24 CSPP1 COPS5
GH08F066118 1.2 FANTOM5 Ensembl ENCODE 12.2 -542.7 -542749 12.7 PKNOX1 ATF1 ZNF133 SIN3A FEZF1 YY1 ZNF121 GATA2 FOS MCM3 C8orf44 CRH GC08P066131 GC08P066135 PIR59286 GC08P066170
GH08F066454 0.9 Ensembl ENCODE 11.5 -211.3 -211310 2.9 PKNOX1 KLF1 DDX20 GTF2E2 JUN MAX ZNF140 SIN3A FOSL1 ZNF316 C8orf46 ADHFE1 C8orf44 RRS1 RRS1-AS1 LOC102724687
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C8orf44 on UCSC Golden Path with GeneCards custom track

Promoters for C8orf44 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001393517 -152 2801 HDGF PKNOX1 ARNT CREB3L1 MLX ARID4B SIN3A DMAP1 YY1 ZNF207

Genomic Location for C8orf44 Gene

Chromosome:
8
Start:
66,667,552 bp from pter
End:
66,685,564 bp from pter
Size:
18,013 bases
Orientation:
Plus strand

Genomic View for C8orf44 Gene

Genes around C8orf44 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C8orf44 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C8orf44 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C8orf44 Gene

Proteins for C8orf44 Gene

  • Protein details for C8orf44 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96CB5-CH044_HUMAN
    Recommended name:
    Putative uncharacterized protein C8orf44
    Protein Accession:
    Q96CB5
    Secondary Accessions:
    • Q9NUM6

    Protein attributes for C8orf44 Gene

    Size:
    159 amino acids
    Molecular mass:
    18380 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C8orf44 Gene

Post-translational modifications for C8orf44 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C8orf44 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C8orf44 Gene

Domains & Families for C8orf44 Gene

Protein Domains for C8orf44 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C8orf44: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C8orf44 Gene

Function for C8orf44 Gene

genes like me logo Genes that share phenotypes with C8orf44: view

Animal Model Products

miRNA for C8orf44 Gene

miRTarBase miRNAs that target C8orf44

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C8orf44 Gene

Localization for C8orf44 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C8orf44 Gene COMPARTMENTS Subcellular localization image for C8orf44 gene
Compartment Confidence
nucleus 5
cytosol 1
extracellular 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for C8orf44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with C8orf44: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C8orf44 Gene

Pathways & Interactions for C8orf44 Gene

SuperPathways for C8orf44 Gene

No Data Available

Interacting Proteins for C8orf44 Gene

Gene Ontology (GO) - Biological Process for C8orf44 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C8orf44 Gene

Transcripts for C8orf44 Gene

Unigene Clusters for C8orf44 Gene

Chromosome 8 open reading frame 44:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C8orf44 Gene

No ASD Table

Relevant External Links for C8orf44 Gene

GeneLoc Exon Structure for
C8orf44
ECgene alternative splicing isoforms for
C8orf44

Expression for C8orf44 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C8orf44 Gene

NURSA nuclear receptor signaling pathways regulating expression of C8orf44 Gene:

C8orf44

SOURCE GeneReport for Unigene cluster for C8orf44 Gene:

Hs.661238
genes like me logo Genes that share expression patterns with C8orf44: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C8orf44 Gene

Orthologs for C8orf44 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C8orf44 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C8H8orf44 34
  • 98.31 (n)
C8orf44 35
  • 96 (a)
OneToOne
Species where no ortholog for C8orf44 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C8orf44 Gene

ENSEMBL:
Gene Tree for C8orf44 (if available)
TreeFam:
Gene Tree for C8orf44 (if available)

Paralogs for C8orf44 Gene

(16) SIMAP similar genes for C8orf44 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with C8orf44: view

No data available for Paralogs for C8orf44 Gene

Variants for C8orf44 Gene

Sequence variations from dbSNP and Humsavar for C8orf44 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs10096544 -- 66,677,916(+) catgg(C/T)gaaac intron-variant, reference, stop-gained
rs10108709 -- 66,681,053(+) tactc(A/G)ggaag intron-variant, utr-variant-3-prime
rs1057463 -- 66,679,917(+) AGGCT(C/T)CTGGA reference, missense, utr-variant-5-prime
rs111245566 -- 66,672,617(+) TGAAT(A/G)TGGTA intron-variant
rs111918384 -- 66,665,571(+) GATTA(C/T)CCATT upstream-variant-2KB, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for C8orf44 Gene

Variant ID Type Subtype PubMed ID
nsv831346 CNV loss 17160897

Variation tolerance for C8orf44 Gene

Residual Variation Intolerance Score: 78.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.50; 64.48% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C8orf44 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C8orf44

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C8orf44 Gene

Disorders for C8orf44 Gene

Relevant External Links for C8orf44

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C8orf44

No disorders were found for C8orf44 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C8orf44 Gene

Publications for C8orf44 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint. (PMID: 26354767) Bailey M.L. … Hieter P. (Genetics 2015) 3 64
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64

Products for C8orf44 Gene

Sources for C8orf44 Gene

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