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Aliases for C8orf33 Gene

Aliases for C8orf33 Gene

  • Chromosome 8 Open Reading Frame 33 2 3

External Ids for C8orf33 Gene

Summaries for C8orf33 Gene

GeneCards Summary for C8orf33 Gene

C8orf33 (Chromosome 8 Open Reading Frame 33) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C8orf33 Gene

Genomics for C8orf33 Gene

Genomic Location for C8orf33 Gene

145,052,378 bp from pter
145,056,030 bp from pter
3,653 bases
Plus strand

Genomic View for C8orf33 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C8orf33 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C8orf33 Gene

Regulatory Elements for C8orf33 Gene

Proteins for C8orf33 Gene

  • Protein details for C8orf33 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UPF0488 protein C8orf33
    Protein Accession:
    Secondary Accessions:
    • A6NGC0
    • Q96BT8

    Protein attributes for C8orf33 Gene

    229 amino acids
    Molecular mass:
    24993 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C8orf33 Gene


neXtProt entry for C8orf33 Gene

Proteomics data for C8orf33 Gene at MOPED

Post-translational modifications for C8orf33 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C8orf33 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C8orf33 Gene

Domains for C8orf33 Gene

Protein Domains for C8orf33 Gene



  • Belongs to the UPF0488 family.:
    • Q9H7E9
genes like me logo Genes that share domains with C8orf33: view

No data available for Gene Families for C8orf33 Gene

Function for C8orf33 Gene

Gene Ontology (GO) - Molecular Function for C8orf33 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 21900206
genes like me logo Genes that share ontologies with C8orf33: view

Phenotypes for C8orf33 Gene

GenomeRNAi human phenotypes for C8orf33:
genes like me logo Genes that share phenotypes with C8orf33: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for C8orf33 Gene

Localization for C8orf33 Gene

Subcellular locations from

Jensen Localization Image for C8orf33 Gene COMPARTMENTS Subcellular localization image for C8orf33 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for C8orf33 Gene

Pathways for C8orf33 Gene

SuperPathways for C8orf33 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C8orf33 Gene


No data available for Pathways by source for C8orf33 Gene

Transcripts for C8orf33 Gene

Unigene Clusters for C8orf33 Gene

Chromosome 8 open reading frame 33:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C8orf33 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d
SP1: -
SP2: -
SP3: -
SP5: -
SP6: - -

Relevant External Links for C8orf33 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C8orf33 Gene

mRNA expression in normal human tissues for C8orf33 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C8orf33 Gene

SOURCE GeneReport for Unigene cluster for C8orf33 Gene Hs.169615

genes like me logo Genes that share expressions with C8orf33: view

Orthologs for C8orf33 Gene

This gene was present in the common ancestor of animals.

Orthologs for C8orf33 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C8orf33 37
  • 96 (a)
LOC464479 36
  • 97.67 (n)
  • 95.63 (a)
(Bos Taurus)
Mammalia C14H8orf33 36
  • 79.79 (n)
  • 75.53 (a)
C8orf33 37
  • 74 (a)
(Canis familiaris)
Mammalia C13H8orf33 36
  • 79.95 (n)
  • 77.54 (a)
C8orf33 37
  • 56 (a)
(Mus musculus)
Mammalia 1110038F14Rik 36
  • 81.7 (n)
  • 77.78 (a)
1110038F14Rik 16
1110038F14Rik 37
  • 65 (a)
(Monodelphis domestica)
Mammalia C8orf33 37
  • 38 (a)
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 49 (a)
-- 37
  • 42 (a)
(Rattus norvegicus)
Mammalia LOC681282 36
  • 72.37 (n)
  • 63.96 (a)
(Anolis carolinensis)
Reptilia C8orf33 37
  • 42 (a)
(Danio rerio)
Actinopterygii C24H8orf33 37
  • 26 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG14286 37
  • 23 (a)
Species with no ortholog for C8orf33:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C8orf33 Gene

Gene Tree for C8orf33 (if available)
Gene Tree for C8orf33 (if available)

Paralogs for C8orf33 Gene Pseudogenes for C8orf33 Gene

genes like me logo Genes that share paralogs with C8orf33: view

No data available for Paralogs for C8orf33 Gene

Variants for C8orf33 Gene

Sequence variations from dbSNP and Humsavar for C8orf33 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs1822 -- 145,054,324(-) TTTGC(C/T)TATCT utr-variant-3-prime
rs1134051 -- 145,055,932(+) gtctt(A/G)tatcc utr-variant-3-prime
rs6599557 -- 145,051,458(+) TGCCC(C/T)CCTGA upstream-variant-2KB
rs6599558 -- 145,056,198(+) tgaca(A/G)gagat downstream-variant-500B
rs6599559 -- 145,056,240(+) taagc(G/T)tgagc downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for C8orf33 Gene

Variant ID Type Subtype PubMed ID
dgv7986n71 CNV Gain 21882294
dgv2265e1 CNV Complex 17122850
nsv466024 CNV Gain 19166990
nsv508533 CNV Loss 20534489
nsv891936 CNV Gain 21882294
nsv466025 CNV Gain 19166990
dgv7988n71 CNV Loss 21882294
nsv824811 CNV Gain 20364138
nsv824812 CNV Gain 20364138
nsv8399 CNV Gain 18304495

Relevant External Links for C8orf33 Gene

HapMap Linkage Disequilibrium report

Disorders for C8orf33 Gene

No disorders were found for C8orf33 Gene.

No data available for UniProtKB/Swiss-Prot for C8orf33 Gene

Publications for C8orf33 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. An empirical framework for binary interactome mapping. (PMID: 19060904) Venkatesan K. … Vidal M. (Nat. Methods 2009) 3
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for C8orf33 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate C8orf33
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for C8orf33
    • Block miRNA regulation of C8orf33 using miScript Target Protectors

    Sources for C8orf33 Gene

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