Aliases for C8orf31 Gene
External Ids for C8orf31 Gene
- HGNC: 26731
- Entrez Gene: 286122
- Ensembl: ENSG00000177335
- UniProtKB: Q8N9H6
Previous GeneCards Identifiers for C8orf31 Gene
- GC08P144193
- GC08P139374
- GC08P144120
Summaries for C8orf31 Gene
GeneCards Summary for C8orf31 Gene
C8orf31 (Chromosome 8 Open Reading Frame 31) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C8orf31 Gene
Genomics for C8orf31 Gene
Regulatory Elements for C8orf31 Gene
Enhancers for C8orf31 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH08G142990 | 1.3 | FANTOM5 ENCODE | 18.4 | -46.2 | -46210 | 4.4 | HDGF ATF1 PKNOX1 ARNT TCF12 ZNF766 ELK1 KLF13 ZNF662 ZNF491 | ZNF623 C8orf31 LOC100133669 CYP11B2 LY6D ENSG00000253715 TSNARE1 LYPD2 CDC42P3 LOC105375794 |
| GH08G143054 | 1.1 | ENCODE | 17.8 | +16.4 | 16377 | 1.9 | HDGF FOXA2 PKNOX1 CREB3L1 ARNT MLX ARID4B SIN3A DMAP1 FEZF1 | C8orf31 JRK ZNF696 ZNF623 AK3P2 GC08P143054 |
| GH08G143047 | 1.1 | Ensembl ENCODE | 17.2 | +9.1 | 9066 | 1.3 | PKNOX1 CBX3 WRNIP1 SIN3A RAD21 RFX5 ZNF143 MIXL1 ZNF654 ZNF362 | C8orf31 ENSG00000243328 GC08P143054 |
| GH08G143038 | 0.9 | ENCODE | 19 | +0.2 | 208 | 1.7 | HDAC1 ELF3 TBP PKNOX1 NFIB ZFP64 ARID4B SIN3A YBX1 TCF12 | ENSG00000243328 C8orf31 GC08P143054 |
| GH08G143042 | 0.8 | ENCODE | 20.8 | +3.7 | 3656 | 1.4 | SOX13 SAP130 ARID4B ZNF48 ZSCAN9 RARA ZNF7 GATAD1 POLR2A NR2F6 | C8orf31 ENSG00000243328 GC08P143054 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around C8orf31 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the C8orf31 gene promoter:
Regulatory Element Products
Genomic Location for C8orf31 Gene
- Chromosome:
- 8
- Start:
- 143,039,209 bp from pter
- End:
- 143,059,942 bp from pter
- Size:
- 20,734 bases
- Orientation:
- Plus strand
Genomic View for C8orf31 Gene
Genes around C8orf31 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8q24.3 by Ensembl
- 8q24.3 by Entrez Gene
- 8q24.3 by HGNC
C8orf31 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C8orf31 Gene
Proteins for C8orf31 Gene
-
Protein details for C8orf31 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N9H6-CH031_HUMAN
- Recommended name:
- Uncharacterized protein C8orf31
- Protein Accession:
- Q8N9H6
- Q6GMU7
Protein attributes for C8orf31 Gene
- Size:
- 132 amino acids
- Molecular mass:
- 14527 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for C8orf31 Gene
No Post-translational modifications
Other Protein References for C8orf31 Gene
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for C8orf31
- Novus Biologicals Antibodies for C8orf31
-
Abcam antibodies for C8orf31
- Invitrogen Antibodies for C8orf31
- Search GeneTex for Antibodies for C8orf31
Protein Products
-
OriGene Purified Proteins for C8orf31
- Search Origene for MassSpec and Protein Over-expression Lysates for C8orf31
- Origene Custom Protein Services for C8orf31
- Novus Biologicals proteins for C8orf31
- Search GeneTex for Proteins for C8orf31
Assay Products
No data available for DME Specific Peptides for C8orf31 Gene
Domains & Families for C8orf31 Gene
Protein Domains for C8orf31 Gene
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C8orf31 Gene
Function for C8orf31 Gene
Phenotypes for C8orf31 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for C8orf31 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for C8orf31 gene
- Search ViGene Biosciences for C8orf31
CRISPR Products
-
OriGene CRISPR knockouts for C8orf31
-
Santa Cruz Biotechnology (SCBT) CRISPR for C8orf31
- GenScript: Design CRISPR guide RNA sequences for C8orf31
miRNA for C8orf31 Gene
- miRTarBase miRNAs that target C8orf31
miRNA Products
- Search ViGene Biosciences for C8orf31
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C8orf31
- Browse OriGene Inhibitory RNA Products For C8orf31
-
ViGene Biosciences ready-to-package AAV shRNAs for C8orf31 gene
Clone Products
-
OriGene ORF clones in human for C8orf31
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- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C8orf31
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C8orf31
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for C8orf31
-
ViGene Biosciences adenoviral particle packaged cDNA for C8orf31 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for C8orf31 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for C8orf31 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C8orf31 Gene
Localization for C8orf31 Gene
| Compartment | Confidence |
|---|---|
| mitochondrion | 2 |
| nucleus | 2 |
| extracellular | 1 |
| cytosol | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C8orf31 Gene
Transcripts for C8orf31 Gene
mRNA/cDNA for C8orf31 Gene
- (4) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (17) Selected AceView cDNA sequences:
- (8) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for C8orf31 Gene
CRISPR Products
-
OriGene CRISPR knockouts for C8orf31
-
Santa Cruz Biotechnology (SCBT) CRISPR for C8orf31
- GenScript: Design CRISPR guide RNA sequences for C8orf31
miRNA Products
- Search ViGene Biosciences for C8orf31
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C8orf31
- Browse OriGene Inhibitory RNA Products For C8orf31
-
ViGene Biosciences ready-to-package AAV shRNAs for C8orf31 gene
Clone Products
-
OriGene ORF clones in human for C8orf31
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C8orf31
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C8orf31
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||
| SP2: | - | - | |||||||||||
| SP3: | - |
Expression for C8orf31 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- NULL (Uncategorized)
NURSA nuclear receptor signaling pathways regulating expression of C8orf31 Gene:
C8orf31SOURCE GeneReport for Unigene cluster for C8orf31 Gene:
Hs.660382Primer Products
-
OriGene qPCR primer pairs for C8orf31
No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C8orf31 Gene
Orthologs for C8orf31 Gene
This gene was present in the common ancestor of human and chimp.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C8orf31 35 |
|
OneToOne | |
| C8H8orf31 34 |
|
- Species where no ortholog for C8orf31 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for C8orf31 Gene
No data available for Paralogs for C8orf31 Gene
Variants for C8orf31 Gene
| SNP ID | Clin | Chr 08 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000090940 | -- | 143,038,108(+) | TCTTA(A/G)GCAGC | upstream-variant-2KB | |
| rs1000119730 | -- | 143,054,798(+) | GGATT(A/G)GCAGG | intron-variant, downstream-variant-500B | |
| rs1000161755 | -- | 143,039,621(+) | GAGGG(A/G)GCTGC | intron-variant | |
| rs1000278669 | -- | 143,054,694(+) | CACTG(G/T)CTACT | intron-variant, downstream-variant-500B | |
| rs1000373376 | -- | 143,043,728(+) | TGGAG(C/T)GCAAT | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1451224 | CNV | insertion | 17803354 |
| esv25583 | CNV | loss | 19812545 |
| esv2670756 | CNV | deletion | 23128226 |
| esv2737948 | CNV | deletion | 23290073 |
| esv2861234 | CNV | insertion | 24192839 |
| esv33872 | CNV | gain | 17666407 |
| esv3619096 | CNV | loss | 21293372 |
| nsv465991 | CNV | loss | 19166990 |
| nsv512976 | CNV | insertion | 21212237 |
| nsv612717 | CNV | loss | 21841781 |
| nsv6437 | CNV | insertion | 18451855 |
Residual Variation Intolerance Score:
80.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.38;
8.32% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for C8orf31 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C8orf31
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C8orf31 Gene
Disorders for C8orf31 Gene
Relevant External Links for C8orf31
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- C8orf31
No disorders were found for C8orf31 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C8orf31 Gene
Publications for C8orf31 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
Products for C8orf31 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Custom Antibody ServicesOriGene Antibodies for C8orf31
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- Custom Assay Services
- OriGene Purified Proteins for C8orf31
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- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C8orf31
- Browse OriGene Inhibitory RNA Products For C8orf31
- OriGene qPCR primer pairs for C8orf31
- OriGene CRISPR knockouts for C8orf31
- OriGene ORF clones in human for C8orf31
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for C8orf31 in any vector
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- GenScript: Design CRISPR guide RNA sequences for C8orf31
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for C8orf31
- Novus Biologicals proteins for C8orf31
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for C8orf31 gene
- ViGene Biosciences lentiviral particle packaged cDNA for C8orf31 gene
- ViGene Biosciences ready-to-package AAV shRNAs for C8orf31 gene
- Search ViGene Biosciences for C8orf31
- Horizon Cell Lines for C8orf31
- Cyagen custom Knockout/knockin (KOKI) mouse models for C8orf31
- VectorBuilder custom plasmid, inducible vectors for C8orf31
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C8orf31
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for C8orf31 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
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- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
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- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
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- (136) ViGene Biosciences
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- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer