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Aliases for C8orf22 Gene

Aliases for C8orf22 Gene

  • Chromosome 8 Open Reading Frame 22 2 3
  • Exocrine Differentiation And Proliferation Factor-Like Protein 4

External Ids for C8orf22 Gene

Previous GeneCards Identifiers for C8orf22 Gene

  • GC00U916963
  • GC08P050148
  • GC08U900617
  • GC08P049984
  • GC08P045448

Summaries for C8orf22 Gene

GeneCards Summary for C8orf22 Gene

C8orf22 (Chromosome 8 Open Reading Frame 22) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C8orf22 Gene

Genomics for C8orf22 Gene

Genomic Location for C8orf22 Gene

Start:
49,054,311 bp from pter
End:
49,076,090 bp from pter
Size:
21,780 bases
Orientation:
Plus strand

Genomic View for C8orf22 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C8orf22 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C8orf22 Gene

No data available for Regulatory Elements for C8orf22 Gene

Proteins for C8orf22 Gene

  • Protein details for C8orf22 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WWR9-PDPFL_HUMAN
    Recommended name:
    Pancreatic progenitor cell differentiation and proliferation factor-like protein
    Protein Accession:
    Q8WWR9
    Secondary Accessions:
    • G3V137
    • Q8WVI1

    Protein attributes for C8orf22 Gene

    Size:
    84 amino acids
    Molecular mass:
    9188 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C8orf22 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C8orf22 Gene

Proteomics data for C8orf22 Gene at MOPED

Post-translational modifications for C8orf22 Gene

No Post-translational modifications

Other Protein References for C8orf22 Gene

No data available for DME Specific Peptides for C8orf22 Gene

Domains for C8orf22 Gene

Protein Domains for C8orf22 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C8orf22 Gene

Graphical View of Domain Structure for InterPro Entry

Q8WWR9

UniProtKB/Swiss-Prot:

PDPFL_HUMAN :
  • Q8WWR9
Family:
  • Belongs to the PPDPF family.
genes like me logo Genes that share domains with C8orf22: view

No data available for Gene Families for C8orf22 Gene

Function for C8orf22 Gene

Animal Model Products

CRISPR Products

miRNA for C8orf22 Gene

miRTarBase miRNAs that target C8orf22

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for C8orf22 Gene

Localization for C8orf22 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C8orf22 Gene COMPARTMENTS Subcellular localization image for C8orf22 gene
Compartment Confidence
mitochondrion 2
peroxisome 2
cytosol 1
extracellular 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C8orf22 Gene

Pathways for C8orf22 Gene

SuperPathways for C8orf22 Gene

No Data Available

Interacting Proteins for C8orf22 Gene

Gene Ontology (GO) - Biological Process for C8orf22 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007275 multicellular organismal development IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with C8orf22: view

No data available for Pathways by source for C8orf22 Gene

Transcripts for C8orf22 Gene

mRNA/cDNA for C8orf22 Gene

(4) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C8orf22 Gene

Chromosome 8 open reading frame 22:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C8orf22

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for C8orf22
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C8orf22 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d · 5e
SP1: -
SP2: - -
SP3:

Relevant External Links for C8orf22 Gene

GeneLoc Exon Structure for
C8orf22
ECgene alternative splicing isoforms for
C8orf22

Expression for C8orf22 Gene

mRNA expression in normal human tissues for C8orf22 Gene

mRNA differential expression in normal tissues according to GTEx for C8orf22 Gene

This gene is overexpressed in Muscle - Skeletal (51.0).

SOURCE GeneReport for Unigene cluster for C8orf22 Gene Hs.49890

genes like me logo Genes that share expressions with C8orf22: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for C8orf22 Gene

Orthologs for C8orf22 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C8orf22 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C8H8orf22 35
  • 100 (n)
  • 100 (a)
C8orf22 36
  • 93 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C14H8orf22 36
  • 42 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C29H8orf22 35
  • 85.23 (n)
  • 81.01 (a)
oppossum
(Monodelphis domestica)
Mammalia C8orf22 36
  • 67 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C8orf22 36
  • 65 (a)
OneToOne
chicken
(Gallus gallus)
Aves C8orf22 36
  • 52 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C8orf22 36
  • 52 (a)
OneToOne
Species with no ortholog for C8orf22:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C8orf22 Gene

ENSEMBL:
Gene Tree for C8orf22 (if available)
TreeFam:
Gene Tree for C8orf22 (if available)

Paralogs for C8orf22 Gene

No data available for Paralogs for C8orf22 Gene

Variants for C8orf22 Gene

Sequence variations from dbSNP and Humsavar for C8orf22 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs168187 -- 49,057,070(+) TTCTT(C/T)CCTTA intron-variant
rs341814 -- 49,066,244(-) CAAAA(A/G)CTGCT intron-variant
rs341815 -- 49,065,865(-) CGGAC(G/T)TCAAT intron-variant
rs818557 -- 49,071,956(+) GGCAG(C/G)TATGT upstream-variant-2KB, intron-variant
rs969066 -- 49,074,775(+) GTGTG(C/G)AGTTG intron-variant, utr-variant-3-prime

Relevant External Links for C8orf22 Gene

HapMap Linkage Disequilibrium report
C8orf22

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C8orf22 Gene

Disorders for C8orf22 Gene

Relevant External Links for C8orf22

Genetic Association Database (GAD)
C8orf22
genes like me logo Genes that share disorders with C8orf22: view

No data available for UniProtKB/Swiss-Prot for C8orf22 Gene

Publications for C8orf22 Gene

  1. Creation of genome-wide protein expression libraries using random activation of gene expression. (PMID: 11329013) Harrington J.J. … Ducar M. (Nat. Biotechnol. 2001) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C. … Lander E.S. (Nature 2006) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for C8orf22 Gene

Sources for C8orf22 Gene

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