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Aliases for C8orf17 Gene

Aliases for C8orf17 Gene

  • Chromosome 8 Open Reading Frame 17 2 3
  • MOLT-4 Sequence Tag-1 3
  • MOST-1 3

External Ids for C8orf17 Gene

Previous GeneCards Identifiers for C8orf17 Gene

  • GC08P139904
  • GC08P141101
  • GC08P140627
  • GC08P140914
  • GC08P141012
  • GC08U901089

Summaries for C8orf17 Gene

GeneCards Summary for C8orf17 Gene

C8orf17 (Chromosome 8 Open Reading Frame 17) is a Protein Coding gene.

UniProtKB/Swiss-Prot for C8orf17 Gene

  • May be involved in cell survival, proliferation and progression of cancer cells.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C8orf17 Gene

Genomics for C8orf17 Gene

Genomic Location for C8orf17 Gene

139,931,172 bp from pter
139,933,946 bp from pter
2,775 bases
Plus strand

Genomic View for C8orf17 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C8orf17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C8orf17 Gene

No data available for Regulatory Elements for C8orf17 Gene

Proteins for C8orf17 Gene

  • Protein details for C8orf17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein MOST-1
    Protein Accession:
    Secondary Accessions:

    Protein attributes for C8orf17 Gene

    99 amino acids
    Molecular mass:
    11219 Da
    Quaternary structure:
    • Interacts with TSPO, IGHM and IGHD.

neXtProt entry for C8orf17 Gene

Proteomics data for C8orf17 Gene at MOPED

Post-translational modifications for C8orf17 Gene

No Post-translational modifications

No data available for DME Specific Peptides for C8orf17 Gene

Domains for C8orf17 Gene

Protein Domains for C8orf17 Gene


Suggested Antigen Peptide Sequences for C8orf17 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C8orf17: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C8orf17 Gene

Function for C8orf17 Gene

Molecular function for C8orf17 Gene

UniProtKB/Swiss-Prot Function:
May be involved in cell survival, proliferation and progression of cancer cells.

Phenotypes for C8orf17 Gene

GenomeRNAi human phenotypes for C8orf17:
genes like me logo Genes that share phenotypes with C8orf17: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C8orf17 Gene

Localization for C8orf17 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C8orf17 Gene

Cytoplasm. Microsome membrane. Endoplasmic reticulum membrane.

Gene Ontology (GO) - Cellular Components for C8orf17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005789 endoplasmic reticulum membrane IEA --
genes like me logo Genes that share ontologies with C8orf17: view

No data available for Subcellular locations from COMPARTMENTS for C8orf17 Gene

Pathways for C8orf17 Gene

SuperPathways for C8orf17 Gene

No Data Available

Interacting Proteins for C8orf17 Gene

Gene Ontology (GO) - Biological Process for C8orf17 Gene


No data available for Pathways by source for C8orf17 Gene

Transcripts for C8orf17 Gene

mRNA/cDNA for C8orf17 Gene

(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for C8orf17 Gene

No ASD Table

Relevant External Links for C8orf17 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C8orf17 Gene

mRNA expression in normal human tissues for C8orf17 Gene

SOURCE GeneReport for Unigene cluster for C8orf17 Gene Hs.283098

mRNA Expression by UniProt/SwissProt for C8orf17 Gene

Tissue specificity: Expressed in the heart, kidney, liver, pancreas, small intestine, ovary, testis, prostate and thymus. Expressed in all of the cancer cell lines tested.
genes like me logo Genes that share expressions with C8orf17: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Expression partners for C8orf17 Gene

Orthologs for C8orf17 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C8orf17 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C8orf17 36
  • 99 (a)
Species with no ortholog for C8orf17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C8orf17 Gene

Gene Tree for C8orf17 (if available)
Gene Tree for C8orf17 (if available)

Paralogs for C8orf17 Gene

(12) SIMAP similar genes for C8orf17 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with C8orf17: view

No data available for Paralogs for C8orf17 Gene

Variants for C8orf17 Gene

Sequence variations from dbSNP and Humsavar for C8orf17 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
VAR_042878 -
VAR_042879 -
VAR_042880 -

Relevant External Links for C8orf17 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C8orf17 Gene

Disorders for C8orf17 Gene

No disorders were found for C8orf17 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for C8orf17 Gene

Publications for C8orf17 Gene

  1. Cellular expression, localization and interactions of the product of the human MOST-1 gene associated with breast and prostate cancers. (PMID: 17143515) Tan J.M.M. … Chow V.T.K. (Int. J. Oncol. 2007) 2 3 4
  2. The novel human MOST-1 (C8orf17) gene exhibits tissue specific expression, maps to chromosome 8q24.2, and is overexpressed/amplified in high grade cancers of the breast and prostate. (PMID: 12665628) Tan J.M.M. … Chow V.T.K. (Mol. Pathol. 2003) 3 4
  3. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3
  4. High-resolution array comparative genomic hybridization of chromosome 8q: evaluation of putative progression markers for gastroesophageal junction adenocarcinomas. (PMID: 18000363) van Duin M. … van Dekken H. (Cytogenet. Genome Res. 2007) 3

Products for C8orf17 Gene

Sources for C8orf17 Gene

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