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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

C8G Gene

protein-coding   GIFtS: 60
GCID: GC09P139839

Complement Component 8, Gamma Polypeptide

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Complement Component 8, Gamma Polypeptide1 2
C8C2
Complement Component C8 Gamma Chain2

External Ids:    HGNC: 13541   Entrez Gene: 7332   Ensembl: ENSG000001769197   OMIM: 1209305   UniProtKB: P073603   

Export aliases for C8G gene to outside databases

Previous GC identifers: GC09U990012 GC09P131529 GC09P133280 GC09P135197 GC09P137115 GC09P138959 GC09P109299


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for C8G Gene:
The protein encoded by this gene belongs to the lipocalin family. It is one of the three subunits that constitutes
complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a
non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on
bacterial cell membranes. While subunits alpha and beta play a role in complement-mediated bacterial killing, the
gamma subunit is not required for the bactericidal activity. (provided by RefSeq, Jul 2011)

GeneCards Summary for C8G Gene: 
C8G (complement component 8, gamma polypeptide) is a protein-coding gene. Diseases associated with C8G include salpingo-oophoritis, and acute salpingitis, and among its related super-pathways are Immune response Lectin induced complement pathway and Complement Pathway. GO annotations related to this gene include complement binding and protein complex binding.

UniProtKB/Swiss-Prot: CO8G_HUMAN, P07360
Function: C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8
complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to
bind retinol




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NT_024000.16  NC_018920.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the C8G gene promoter:
         USF1   p53   AML1a   AP-2gamma   HEN1   PPAR-gamma1   USF-1   STAT3   PPAR-gamma2   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidC8G promoter sequence
   Search SABiosciences Chromatin IP Primers for C8G

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C8G


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.3   Ensembl cytogenetic band:  9q34.3   HGNC cytogenetic band: 9q

C8G Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C8G gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P139839:  view genomic region     (about GC identifiers)

Start:
139,839,698 bp from pter      End:
139,841,426 bp from pter
Size:
1,729 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CO8G_HUMAN, P07360 (See protein sequence)
Recommended Name: Complement component C8 gamma chain precursor  
Size: 202 amino acids; 22277 Da
Subunit: C8 is composed of three chains: alpha, beta and gamma. The alpha and gamma chains are disulfide bonded
Subcellular location: Secreted
6/8 PDB 3D structures from and Proteopedia for C8G (see all 8):
1IW2 (3D)        1LF7 (3D)        2OVA (3D)        2OVD (3D)        2OVE (3D)        2QOS (3D)    
Secondary accessions: Q14CT8 Q14CU0 Q5SQ07

Explore the universe of human proteins at neXtProt for C8G: NX_P07360

Explore proteomics data for C8G at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P07360

  • C8G Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    C8G Protein Expression
    REFSEQ proteins: NP_000597.2  
    ENSEMBL proteins: 
     ENSP00000360697   ENSP00000224181  
    Reactome Protein details: P07360
    Human Recombinant Protein Products for C8G: 
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    Novus Biologicals C8G Proteins
    Novus Biologicals C8G Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for C8G
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005579membrane attack complex IEA--
    GO:0005615extracellular space IEA--

    C8G for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    LCN: Lipocalins
    complement: Complement system

    5/6 InterPro protein domains (see all 6):
     IPR022272 Lipocalin_CS
     IPR000566 Lipocln_cytosolic_FA-bd_dom
     IPR012674 Calycin
     IPR011038 Calycin-like
     IPR002968 A1-microglobln

    Graphical View of Domain Structure for InterPro Entry P07360

    ProtoNet protein and cluster: P07360

    2 Blocks protein domains:
    IPB002345 Lipocalin signature
    IPB002968 Alpha-1-microglobulin signature


    UniProtKB/Swiss-Prot: CO8G_HUMAN, P07360
    Similarity: Belongs to the calycin superfamily. Lipocalin family


    C8G for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CO8G_HUMAN, P07360
    Function: C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8
    complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to
    bind retinol

         Genatlas biochemistry entry for C8G:
    complement component 8,gamma-1 globulin,complexing with other late components of the cascade to form the membrane
    attacks complex,gamma,(lipocalin family,Kernel group),associating with CD59,potential regulator of the complex
    helping to protect host cells from lysis

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001848complement binding IEA--
    GO:0019841retinol binding IEA--
    GO:0032403protein complex binding IEA--
         
    C8G for ontologies           About GeneDecksing


    Animal Models:
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for C8G About   (see all 9)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Immune response Lectin induced complement pathway
    Immune response Lectin induced complement pathway0.56
    Immune response Classic complement pathway0.53
    Immune response Alternative complement pathway0.56
    Immune response Classical complement pathway0.52
    Immune response Lectin Induced complement pathway0.56
    Regulation of Complement cascade0.50
    2Classical Complement Pathway
    Classical Complement Pathway0.75
    Lectin Induced Complement Pathway0.65
    Complement Pathway0.75
    Complement Activation Pathways0.31
    3Complement and coagulation cascades
    Complement and Coagulation Cascades0.71
    Complement and coagulation cascades0.71
    4Terminal pathway of complement
    Terminal pathway of complement0.64
    Alternative Complement Pathway0.64
    5Immune System
    Immune System0.56
    Innate Immune System0.50

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    3 EMD Millipore Pathways for C8G
        Immune response Alternative complement pathway
    Immune response Classic complement pathway
    Immune response Lectin Induced complement pathway

    4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for C8G
        Alternative Complement Pathway
    Classical Complement Pathway
    Lectin Induced Complement Pathway
    Complement Pathway

    3 GeneGo (Thomson Reuters) Pathways for C8G
        Immune response Alternative complement pathway
    Immune response Classical complement pathway
    Immune response Lectin induced complement pathway

    1 BioSystems Pathway for C8G
        Complement and Coagulation Cascades

    1 Sino Biological Pathway for C8G 
        Complement Activation Pathways

    5        Reactome Pathways for C8G
        Terminal pathway of complement
    Regulation of Complement cascade
    Complement cascade
    Immune System
    Innate Immune System


    4         Kegg Pathways  (Kegg details for C8G):
        Complement and coagulation cascades
    Prion diseases
    Amoebiasis
    Systemic lupus erythematosus


    C8G for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C8G

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/8 Interacting proteins for C8G (P073603 ENSP000002241814) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    C8AP073573, ENSP000003544584I2D: score=2 STRING: ENSP00000354458
    SH3GL2Q999623I2D: score=1 
    C5ENSP000002236424STRING: ENSP00000223642
    C8BENSP000003602814STRING: ENSP00000360281
    C9ENSP000002634084STRING: ENSP00000263408
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006957complement activation, alternative pathway IEA--
    GO:0006958complement activation, classical pathway IEA--
    GO:0019835cytolysis IEA--
    GO:0030449regulation of complement activation TAS--
    GO:0045087innate immune response TAS--

    C8G for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for C8G (CO8G)

    1 DrugBank Compound for C8G    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Citric Acid-- 77-92-9target----

    Search CenterWatch for drugs/clinical trials and news about C8G / CO8G

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for C8G gene: 
    NM_000606.2  

    Unigene Cluster for C8G:

    Complement component 8, gamma polypeptide
    Hs.1285  [show with all ESTs]
    Unigene Representative Sequence: NM_000606
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371634 ENST00000224181(uc004cka.2) ENST00000484376 ENST00000465773

    miRNA
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    Additional mRNA sequence: 

    BC113624.1 BC113626.1 M17263.1 M17999.1 X06465.1 

    2 DOTS entries:

    DT.309324  DT.91654872 

    24/32 AceView cDNA sequences (see all 32):

    BM790818 AA588777 NM_000606 M17999 BV198286 BV197486 BM850834 T28652 
    BM849587 AA894707 BM790809 BX282392 BM790630 BV198188 X06465 CB157535 
    BV198189 AW340666 AV693786 AV684369 AW080648 AW304460 AA344866 BM852158 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for C8G    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b
    SP1:                                                
    SP2:                                                
    SP3:              -                                 


    ECgene alternative splicing isoforms for C8G

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    C8G expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTGTCAGTA
    C8G Expression
    About this image


    See C8G Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for C8G

    SOURCE GeneReport for Unigene cluster: Hs.1285
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C8G

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for C8G gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia C8g1 , 5 complement component 8, gamma polypeptide1, 5 77.23(n)1
    73.76(a)1
      2 (17.31 cM)5
    693791  NM_027062.11  NP_081338.11 
     254986515 
    chicken
    (Gallus gallus)
    Aves C8G1 complement component 8, gamma polypeptide 59.5(n)
    47.93(a)
      770691  XM_001234026.2  XP_001234027.2 
    zebrafish
    (Danio rerio)
    Actinopterygii c8g1 complement component 8, gamma polypeptide 47.62(n)
    37.14(a)
      393837  NM_200863.1  NP_957157.1 


    ENSEMBL Gene Tree for C8G (if available)
    TreeFam Gene Tree for C8G (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for C8G gene
    1 SIMAP similar gene for C8G using alignment to 2 protein entries:     CO8G_HUMAN (see all proteins):
    LCN15

    C8G for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/216 SNPs in C8G are shown (see all 216)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1823044071,2
    C--139874629(+) GCTGCA/GGCAGA 1 -- us2k10--------
    rs1127899241,2
    C--139874667(+) CCGTCA/C/GTCACC 1 -- us2k11CSA 1
    rs1126966211,2
    C--139874670(+) TCCTCA/G/TCCTTC 1 -- us2k11CSA 1
    rs1478210011,2
    C,F--139874678(+) TTCACA/GGTGCA 1 -- us2k11Minor allele frequency- G:0.00NA 4538
    rs2001120081,2
    --139874687(+) CAGTCC/TTTGGA 1 -- us2k10--------
    rs1423202321,2
    C,F--139874702(+) GACGCG/AAACTG 1 -- us2k11Minor allele frequency- A:0.00NA 4538
    rs1512827441,2
    F--139874750(+) TCTGTG/ATGTTC 1 -- us2k11Minor allele frequency- A:0.00NA 4530
    rs1141808401,2
    --139874819(+) TACCAA/GGACAT 1 -- us2k10--------
    rs2010913131,2
    --139874833(+) CGCTGC/TGGGTG 1 -- us2k10--------
    rs22718721,2
    C,F,A--139874861(-) AGGCCG/CGGGCC 1 -- us2k111Minor allele frequency- C:0.35NA WA CSA EA EU 545

    HapMap Linkage Disequilibrium report for C8G (139839698 - 139841426 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/17 variations for C8G (see all 17):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2422220CNV Deletion17116639
    nsv894483CNV Loss21882294
    dgv8416n71CNV Loss21882294
    nsv894503CNV Loss21882294
    dgv8423n71CNV Loss21882294
    nsv894469CNV Loss21882294
    nsv524322CNV Loss19592680
    nsv894502CNV Loss21882294
    dgv8415n71CNV Loss21882294
    nsv469918CNV Loss18288195

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 120930    OMIM disorders: --

    11 diseases for C8G:    About MalaCards
    salpingo-oophoritis    acute salpingitis    salpingitis    oophoritis
    prion disease    cystadenoma    meningioma    systemic lupus erythematosus
    lupus erythematosus    gastric cancer    leukemia

    2 diseases from the University of Copenhagen DISEASES database for C8G:
    salpingo-oophoritis     Acute salpingitis

    C8G for disorders           About GeneDecksing

    Genetic Association Database (GAD): C8G
    Human Genome Epidemiology (HuGE) Navigator: C8G (4 documents)

    Export disorders for C8G gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for C8G gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with C8G)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Polymorphisms in innate immunity genes and risk of ch ildhood leukemia. (PubMed id 20438785)1, 4 Han S....Kang D. (2010)
    2. Risk of meningioma and common variation in genes rela ted to innate immunity. (PubMed id 20406964)1, 4 Rajaraman P....Inskip P.D. (2010)
    3. Structural features of the ligand binding site on human complement protein C8gamma: a member of the lipocalin family. (PubMed id 17452033)1, 2 Chiswell B....Sodetz J.M. (2007)
    4. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    5. Crystal structure of human complement protein C8gamma at 1.2 A resolution reveals a lipocalin fold and a distinct ligand binding site. (PubMed id 12033936)1, 2 Ortlund E.... Lebioda L. (2002)
    6. Human complement protein C8 gamma. (PubMed id 11058761)1, 2 Schreck S.F.... Sodetz J.M. (2000)
    7. Genomic structure of the human complement protein C8 gamma: homology to the lipocalin gene family. (PubMed id 8172891)1, 2 Kaufman K.M. and Sodetz J.M. (1994)
    8. Structural and functional characterization of complement C8 gamma, a member of the lipocalin protein family. (PubMed id 1707134)1, 2 Haefliger J.-A.... Tschopp J. (1991)
    9. Structural homology of human complement component C8 gamma and plasma protein HC: identity of the cysteine bond pattern. (PubMed id 2447883)1, 2 Haefliger J.-A.... Tschopp J. (1987)
    10. The eighth component of human complement: evidence that it is an oligomeric serum protein assembled from products of three different genes. (PubMed id 3676249)1, 2 Ng S.C.... Sodetz J.M. (1987)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 733 HGNC: 1354 AceView: C8G Ensembl:ENSG00000176919 euGenes: HUgn733
    ECgene: C8G Kegg: 733 H-InvDB: C8G

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for C8G Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for C8G gene:
    Search GeneIP for patents involving C8G

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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