Aliases for C7orf73 Gene
Aliases for C7orf73 Gene
External Ids for C7orf73 Gene
- HGNC: 41909
- Entrez Gene: 647087
- Ensembl: ENSG00000243317
- UniProtKB: E0CX11
Previous GeneCards Identifiers for C7orf73 Gene
- GC07P135350
Summaries for C7orf73 Gene
GeneCards Summary for C7orf73 Gene
C7orf73 (Chromosome 7 Open Reading Frame 73) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C7orf73 Gene
Genomics for C7orf73 Gene
Regulatory Elements for C7orf73 Gene
Enhancers for C7orf73 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around C7orf73 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for C7orf73 Gene
- Chromosome:
- 7
- Start:
- 135,662,473 bp from pter
- End:
- 135,693,418 bp from pter
- Size:
- 30,946 bases
- Orientation:
- Plus strand
Genomic View for C7orf73 Gene
Genes around C7orf73 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 7q33 by Ensembl
- 7q33 by Entrez Gene
- 7q33 by HGNC
C7orf73 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C7orf73 Gene
Proteins for C7orf73 Gene
-
Protein details for C7orf73 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- E0CX11-CG073_HUMAN
- Recommended name:
- Uncharacterized protein C7orf73
- Protein Accession:
- E0CX11
Protein attributes for C7orf73 Gene
- Size:
- 47 amino acids
- Molecular mass:
- 5265 Da
- Quaternary structure:
- No Data Available
Protein Expression for C7orf73 Gene
Post-translational modifications for C7orf73 Gene
Other Protein References for C7orf73 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for C7orf73
- Invitrogen Antibodies for C7orf73
- Search GeneTex for Antibodies for C7orf73
Protein Products
-
OriGene Purified Proteins for C7orf73
- Search Origene for MassSpec and Protein Over-expression Lysates for C7orf73
- Origene Custom Protein Services for C7orf73
- Novus Biologicals proteins for C7orf73
- Search GeneTex for Proteins for C7orf73
Assay Products
No data available for DME Specific Peptides for C7orf73 Gene
Domains & Families for C7orf73 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C7orf73 Gene
Function for C7orf73 Gene
Phenotypes for C7orf73 Gene
- GenomeRNAi human phenotypes for C7orf73:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for C7orf73
-
- Search ViGene Biosciences for C7orf73
CRISPR Products
-
OriGene CRISPR knockouts for C7orf73
-
Santa Cruz Biotechnology (SCBT) CRISPR for C7orf73
- GenScript: Design CRISPR guide RNA sequences for C7orf73
miRNA for C7orf73 Gene
- miRTarBase miRNAs that target C7orf73
-
- hsa-mir-6510-3p (MIRT480284)
- hsa-mir-4688 (MIRT480285)
- hsa-mir-6720-5p (MIRT480286)
- hsa-mir-6512-3p (MIRT480287)
- hsa-mir-6721-5p (MIRT480288)
- hsa-mir-661 (MIRT480289)
- hsa-mir-873-3p (MIRT480290)
- hsa-mir-4522 (MIRT480291)
- hsa-mir-6860 (MIRT480292)
- hsa-mir-612 (MIRT480293)
- hsa-mir-5189-5p (MIRT480294)
- hsa-mir-3187-5p (MIRT480295)
- hsa-mir-1285-3p (MIRT480296)
- hsa-mir-766-3p (MIRT480297)
- hsa-mir-6849-3p (MIRT480298)
- hsa-mir-939-3p (MIRT480299)
- hsa-mir-922 (MIRT480300)
- hsa-mir-759 (MIRT480301)
- hsa-mir-5586-3p (MIRT480302)
- hsa-mir-3664-5p (MIRT480303)
- hsa-mir-508-5p (MIRT480304)
- hsa-mir-6516-5p (MIRT524614)
- hsa-mir-6807-5p (MIRT524615)
- hsa-mir-455-3p (MIRT524616)
- hsa-mir-650 (MIRT524617)
- hsa-mir-3612 (MIRT524618)
- hsa-mir-6499-3p (MIRT524619)
- hsa-mir-4722-5p (MIRT524620)
- hsa-mir-1827 (MIRT524621)
- hsa-mir-4433a-3p (MIRT524622)
- hsa-mir-940 (MIRT524623)
- hsa-mir-6893-5p (MIRT524624)
- hsa-mir-6808-5p (MIRT524625)
- hsa-mir-6864-3p (MIRT524626)
- hsa-mir-3672 (MIRT524627)
- hsa-mir-187-5p (MIRT526300)
- hsa-mir-4766-5p (MIRT526301)
- hsa-mir-1283 (MIRT526302)
- hsa-mir-6507-5p (MIRT526303)
- hsa-mir-186-5p (MIRT526304)
- hsa-mir-4668-5p (MIRT624504)
- hsa-mir-4641 (MIRT624505)
- hsa-mir-3613-3p (MIRT624506)
miRNA Products
- Search ViGene Biosciences for C7orf73
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for C7orf73
- Browse OriGene Inhibitory RNA Products For C7orf73
- Search ViGene Biosciences for C7orf73
Clone Products
-
OriGene ORF clones in human for C7orf73
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for C7orf73
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C7orf73
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for C7orf73
-
ViGene Biosciences adenoviral particle packaged cDNA for C7orf73 gene
- Search ViGene Biosciences for C7orf73
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C7orf73 Gene
Localization for C7orf73 Gene
Subcellular locations from UniProtKB/Swiss-Prot for C7orf73 Gene
- Mitochondrion membrane; Single-pass membrane protein.
| Compartment | Confidence |
|---|---|
| mitochondrion | 3 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
| GO:0031966 | mitochondrial membrane | IEA | -- |
Transcripts for C7orf73 Gene
mRNA/cDNA for C7orf73 Gene
- (1) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for C7orf73 Gene
- Chromosome 7 open reading frame 73:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for C7orf73
-
Santa Cruz Biotechnology (SCBT) CRISPR for C7orf73
- GenScript: Design CRISPR guide RNA sequences for C7orf73
miRNA Products
- Search ViGene Biosciences for C7orf73
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for C7orf73
- Browse OriGene Inhibitory RNA Products For C7orf73
- Search ViGene Biosciences for C7orf73
Clone Products
-
OriGene ORF clones in human for C7orf73
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for C7orf73
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C7orf73
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for C7orf73 Gene
This gene is overexpressed in Oral epithelium (29.5), Fetal ovary (22.8), and Testis (16.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C7orf73 Gene
NURSA nuclear receptor signaling pathways regulating expression of C7orf73 Gene:
C7orf73SOURCE GeneReport for Unigene cluster for C7orf73 Gene:
Hs.200022Primer Products
-
OriGene qPCR primer pairs for C7orf73
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C7orf73 Gene
Orthologs for C7orf73 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C7orf73 35 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | PL-5283 35 |
|
OneToMany |
- Species where no ortholog for C7orf73 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for C7orf73 Gene
Pseudogenes.org Pseudogenes for C7orf73 Gene
No data available for Paralogs for C7orf73 Gene
Variants for C7orf73 Gene
| SNP ID | Clin | Chr 07 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000193056 | -- | 135,663,687(+) | GTCCC(A/G)CTCTG | intron-variant | |
| rs1000224094 | -- | 135,663,910(+) | AAGTG(C/T)TGGGA | intron-variant | |
| rs1000310133 | -- | 135,660,711(+) | TTTGG(A/G)AGGCC | upstream-variant-2KB | |
| rs1000321893 | -- | 135,673,390(+) | CAAGG(A/G)AAACA | intron-variant | |
| rs1000530772 | -- | 135,662,529(+) | CGGCC(A/C/G)GCGGA | utr-variant-5-prime |
Gene Damage Index Score:
0.66;
14.03% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for C7orf73 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C7orf73
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C7orf73 Gene
Disorders for C7orf73 Gene
Relevant External Links for C7orf73
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- C7orf73
No disorders were found for C7orf73 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C7orf73 Gene
Publications for C7orf73 Gene
- N-terminome analysis of the human mitochondrial proteome. (PMID: 25944712) Vaca Jacome A.S. … Carapito C. (Proteomics 2015) 4 64
- Identification of membrane proteins by tandem mass spectrometry of protein ions. (PMID: 17720804) Carroll J. … Walker J.E. (Proc. Natl. Acad. Sci. U.S.A. 2007) 3 64
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
- The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
Products for C7orf73 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Browse Proteome Profiler Antibody Arrays
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- Custom Antibody Services
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- Custom Assay Services
- OriGene Purified Proteins for C7orf73
- Search Origene for MassSpec and Protein Over-expression Lysates for C7orf73
- Origene Custom Protein Services for C7orf73
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C7orf73
- Browse OriGene Inhibitory RNA Products For C7orf73
- OriGene qPCR primer pairs for C7orf73
- OriGene CRISPR knockouts for C7orf73
- OriGene ORF clones in human for C7orf73
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for C7orf73 in any vector
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- GenScript: Design CRISPR guide RNA sequences for C7orf73
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- Browse Sino Biological cDNA Clones
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- Novus Biologicals Antibodies for C7orf73
- Novus Biologicals proteins for C7orf73
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Invitrogen Antibodies for C7orf73
- ViGene Biosciences adenoviral particle packaged cDNA for C7orf73 gene
- Search ViGene Biosciences for C7orf73
- Horizon Cell Lines for C7orf73
- Cyagen custom Knockout/knockin (KOKI) mouse models for C7orf73
- VectorBuilder custom plasmid, inducible vectors for C7orf73
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C7orf73
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for C7orf73 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer