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Aliases for C7orf69 Gene

Aliases for C7orf69 Gene

  • Chromosome 7 Open Reading Frame 69 2 3 5

External Ids for C7orf69 Gene

Previous GeneCards Identifiers for C7orf69 Gene

  • GC07P047802
  • GC07P047718

Summaries for C7orf69 Gene

GeneCards Summary for C7orf69 Gene

C7orf69 (Chromosome 7 Open Reading Frame 69) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C7orf69 Gene

Genomics for C7orf69 Gene

Regulatory Elements for C7orf69 Gene

Enhancers for C7orf69 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F047771 0.2 ENCODE 12.3 -23.4 -23364 1.7 CTCF ZMYM3 KDM1A TNS3 LINC00525 C7orf69 PKD1L1 ABCA13
GH07F047819 0.5 Ensembl 12.1 +23.9 23911 0.4 GTF2F1 CTCF SAP130 DNMT3B RAD21 ZNF143 SMC3 MIXL1 THAP11 GATAD2A C7orf69 C7orf65 GC07M047823
GH07F047820 0.2 ENCODE 12.1 +24.2 24217 0.2 GTF2F1 CTCF SAP130 DNMT3B RAD21 ZNF143 SMC3 MIXL1 THAP11 GATAD2A C7orf69 C7orf65 GC07M047823
GH07F047732 0.2 ENCODE 11.4 -62.1 -62080 1.0 GATAD2A NR2F1 ARID4B ZMYM3 CEBPG THRB RARA ZGPAT ZKSCAN8 CEBPA C7orf69 LINC00525 C7orf65
GH07F047620 1.2 Ensembl ENCODE 11.3 -172.7 -172732 3.3 ELF3 MLX ARID4B DMAP1 THRB ZNF48 ZSCAN9 RAD21 RARA FOS TNS3 C7orf65 C7orf69 LINC01447
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C7orf69 on UCSC Golden Path with GeneCards custom track

Genomic Location for C7orf69 Gene

Chromosome:
7
Start:
47,795,291 bp from pter
End:
47,819,847 bp from pter
Size:
24,557 bases
Orientation:
Plus strand

Genomic View for C7orf69 Gene

Genes around C7orf69 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C7orf69 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C7orf69 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C7orf69 Gene

Proteins for C7orf69 Gene

  • Protein details for C7orf69 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H7B7-CG069_HUMAN
    Recommended name:
    Uncharacterized protein C7orf69
    Protein Accession:
    Q9H7B7
    Secondary Accessions:
    • A4D2F1
    • Q14CN7
    • Q75MJ5

    Protein attributes for C7orf69 Gene

    Size:
    122 amino acids
    Molecular mass:
    14425 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C7orf69 Gene

Post-translational modifications for C7orf69 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C7orf69 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C7orf69 Gene

Domains & Families for C7orf69 Gene

Protein Domains for C7orf69 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C7orf69: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C7orf69 Gene

Function for C7orf69 Gene

Phenotypes for C7orf69 Gene

genes like me logo Genes that share phenotypes with C7orf69: view

Animal Model Products

miRNA for C7orf69 Gene

miRTarBase miRNAs that target C7orf69

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C7orf69 Gene

Localization for C7orf69 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C7orf69 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C7orf69 Gene COMPARTMENTS Subcellular localization image for C7orf69 gene
Compartment Confidence
extracellular 4
cytosol 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for C7orf69 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with C7orf69: view

Pathways & Interactions for C7orf69 Gene

SuperPathways for C7orf69 Gene

No Data Available

Interacting Proteins for C7orf69 Gene

Gene Ontology (GO) - Biological Process for C7orf69 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C7orf69 Gene

Transcripts for C7orf69 Gene

mRNA/cDNA for C7orf69 Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C7orf69 Gene

Chromosome 7 open reading frame 69:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C7orf69 Gene

No ASD Table

Relevant External Links for C7orf69 Gene

GeneLoc Exon Structure for
C7orf69
ECgene alternative splicing isoforms for
C7orf69

Expression for C7orf69 Gene

mRNA expression in normal human tissues for C7orf69 Gene

mRNA differential expression in normal tissues according to GTEx for C7orf69 Gene

This gene is overexpressed in Testis (x9.9).

Protein differential expression in normal tissues from HIPED for C7orf69 Gene

This gene is overexpressed in Adipocyte (67.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C7orf69 Gene



Protein tissue co-expression partners for C7orf69 Gene

NURSA nuclear receptor signaling pathways regulating expression of C7orf69 Gene:

C7orf69

SOURCE GeneReport for Unigene cluster for C7orf69 Gene:

Hs.287647
genes like me logo Genes that share expression patterns with C7orf69: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C7orf69 Gene

Orthologs for C7orf69 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C7orf69 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C7H7orf69 34
  • 98.97 (n)
C7orf69 35
  • 97 (a)
OneToOne
Species where no ortholog for C7orf69 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C7orf69 Gene

ENSEMBL:
Gene Tree for C7orf69 (if available)
TreeFam:
Gene Tree for C7orf69 (if available)

Paralogs for C7orf69 Gene

No data available for Paralogs for C7orf69 Gene

Variants for C7orf69 Gene

Sequence variations from dbSNP and Humsavar for C7orf69 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10231581 -- 47,794,377(+) atggc(C/T)gaaag intron-variant, upstream-variant-2KB
rs10269813 -- 47,796,759(+) AAGGC(A/G)GGCGG intron-variant
rs10271005 -- 47,814,298(+) CTCCA(C/G)TGTCA intron-variant
rs10600940 -- 47,797,000(+) GTCTC(-/A)AAAAA intron-variant
rs1074780 -- 47,808,081(-) AGGGC(C/T)TGAAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C7orf69 Gene

Variant ID Type Subtype PubMed ID
esv3613065 CNV gain 21293372
esv3613069 CNV gain 21293372
nsv479213 CNV novel sequence insertion 20440878
nsv830990 CNV loss 17160897
nsv830991 CNV loss 17160897

Variation tolerance for C7orf69 Gene

Residual Variation Intolerance Score: 65.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.05; 1.19% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C7orf69 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C7orf69

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C7orf69 Gene

Disorders for C7orf69 Gene

Relevant External Links for C7orf69

Genetic Association Database (GAD)
C7orf69
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C7orf69

No disorders were found for C7orf69 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C7orf69 Gene

Publications for C7orf69 Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4 64
  2. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3 4 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for C7orf69 Gene

Sources for C7orf69 Gene

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