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Aliases for C7orf66 Gene

Aliases for C7orf66 Gene

  • Chromosome 7 Open Reading Frame 66 2 3

External Ids for C7orf66 Gene

Previous GeneCards Identifiers for C7orf66 Gene

  • GC07M108312
  • GC07M108524
  • GC07M102892

Summaries for C7orf66 Gene

GeneCards Summary for C7orf66 Gene

C7orf66 (Chromosome 7 Open Reading Frame 66) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C7orf66 Gene

Genomics for C7orf66 Gene

Regulatory Elements for C7orf66 Gene

Genomic Location for C7orf66 Gene

Chromosome:
7
Start:
108,883,975 bp from pter
End:
108,896,211 bp from pter
Size:
12,237 bases
Orientation:
Minus strand

Genomic View for C7orf66 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for C7orf66 Gene

Proteins for C7orf66 Gene

  • Protein details for C7orf66 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A4D0T2-CG066_HUMAN
    Recommended name:
    Uncharacterized protein C7orf66
    Protein Accession:
    A4D0T2

    Protein attributes for C7orf66 Gene

    Size:
    115 amino acids
    Molecular mass:
    13234 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C7orf66 Gene

Proteomics data for C7orf66 Gene at MOPED

Post-translational modifications for C7orf66 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C7orf66 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C7orf66 Gene

Domains & Families for C7orf66 Gene

Protein Domains for C7orf66 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C7orf66: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C7orf66 Gene

Function for C7orf66 Gene

Phenotypes for C7orf66 Gene

genes like me logo Genes that share phenotypes with C7orf66: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C7orf66

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C7orf66 Gene

Localization for C7orf66 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C7orf66 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for C7orf66 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C7orf66: view

No data available for Subcellular locations from COMPARTMENTS for C7orf66 Gene

Pathways & Interactions for C7orf66 Gene

SuperPathways for C7orf66 Gene

No Data Available

Interacting Proteins for C7orf66 Gene

Gene Ontology (GO) - Biological Process for C7orf66 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C7orf66 Gene

Drugs & Compounds for C7orf66 Gene

No Compound Related Data Available

Transcripts for C7orf66 Gene

mRNA/cDNA for C7orf66 Gene

(2) REFSEQ mRNAs :
(30) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C7orf66 Gene

Chromosome 7 open reading frame 66:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C7orf66

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C7orf66 Gene

No ASD Table

Relevant External Links for C7orf66 Gene

GeneLoc Exon Structure for
C7orf66
ECgene alternative splicing isoforms for
C7orf66

Expression for C7orf66 Gene

mRNA expression in normal human tissues for C7orf66 Gene

mRNA differential expression in normal tissues according to GTEx for C7orf66 Gene

This gene is overexpressed in Testis (x51.6).

SOURCE GeneReport for Unigene cluster for C7orf66 Gene Hs.276325

genes like me logo Genes that share expression patterns with C7orf66: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C7orf66 Gene

Orthologs for C7orf66 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C7orf66 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C7H7orf66 35
  • 94.84 (n)
  • 91.67 (a)
C7orf66 36
  • 96 (a)
OneToOne
Species with no ortholog for C7orf66:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C7orf66 Gene

ENSEMBL:
Gene Tree for C7orf66 (if available)
TreeFam:
Gene Tree for C7orf66 (if available)

Paralogs for C7orf66 Gene

No data available for Paralogs for C7orf66 Gene

Variants for C7orf66 Gene

Sequence variations from dbSNP and Humsavar for C7orf66 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs711447 -- 108,884,934(-) TGTAT(C/T)AGAAA upstream-variant-2KB, intron-variant
rs848361 -- 108,897,964(-) ATGAC(A/T)TATAG upstream-variant-2KB
rs848362 -- 108,897,602(-) TTCCC(A/C/G)CAGAC upstream-variant-2KB
rs848363 -- 108,897,439(-) ATTAG(C/G)TTGCA upstream-variant-2KB
rs848364 -- 108,897,001(-) TTTAC(C/T)ATCAG upstream-variant-2KB

Variation tolerance for C7orf66 Gene

Residual Variation Intolerance Score: 80.01% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.05; 21.56% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C7orf66 Gene

HapMap Linkage Disequilibrium report
C7orf66

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C7orf66 Gene

Disorders for C7orf66 Gene

Relevant External Links for C7orf66

Genetic Association Database (GAD)
C7orf66
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C7orf66
genes like me logo Genes that share disorders with C7orf66: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C7orf66 Gene

Publications for C7orf66 Gene

  1. A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants. (PMID: 22219177) Tao S. … Sun J. (Carcinogenesis 2012) 67
  2. Large-scale genome-wide association study of Asian population reveals genetic factors in FRMD4A and other loci influencing smoking initiation and nicotine dependence. (PMID: 22006218) Yoon D. … Park T. (Hum. Genet. 2012) 67
  3. A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population. (PMID: 22318345) Cha P.C. … Nakamura Y. (J. Hum. Genet. 2012) 67
  4. Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness. (PMID: 17903302) Levy D. … Mitchell G.F. (BMC Med. Genet. 2007) 67
  5. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PMID: 17903299) Kathiresan S. … Cupples L.A. (BMC Med. Genet. 2007) 67

Products for C7orf66 Gene

Sources for C7orf66 Gene

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