C7orf66 Gene
protein-coding GIFtS: 31
GCID: GC07M108524 (predicted)
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chromosome 7 open reading frame 66
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Aliases
for C7orf66 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 7 Open Reading Frame 661 2 | | Putative Uncharacterized Protein LOC1549072 | | Uncharacterized Protein C7orf662 |
Export aliases for C7orf66 gene to outside databasesPrevious GC identifers: GC07M108312 GC07M102892 |
Summaries
for C7orf66 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C7orf66 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C7orf66 gene promoter:
Nkx3-1 v4 ATF-2 FOXD3 HSF1 (long) POU3F2 Meis-1b S8 HSF1short Meis-1a Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for C7orf66
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C7orf66 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q31.1 Ensembl cytogenetic band: 7q31.1 HGNC cytogenetic band: 7q31.1C7orf66 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07M108524: view genomic region
(about GC identifiers)
Start:
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108,524,032 bp from pter |
End:
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108,524,644 bp from pter |
Size:
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613 bases |
Orientation:
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minus strand |
1 alternative location:
| Chr7-,CRA_TCAG 107,891,336-107,891,936 |
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Proteins
for C7orf66 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CG066_HUMAN, A4D0T2 (See
protein sequence)Recommended Name: Uncharacterized protein C7orf66 Size: 115 amino acids; 13234 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)Explore the universe of human proteins at neXtProt for C7orf66: NX_A4D0T2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A4D0T2
C7orf66 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001019778.1
ENSEMBL proteins: ENSP00000368292
Human Recombinant Protein Products for C7orf66:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
C7orf66 for ontologies About GeneDecksing
C7orf66 Antibody Products:
Assay Products for C7orf66: |
Protein
Domains /
Families
for C7orf66 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: A4D0T2 |
Function
for C7orf66 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Phenotypes:
1 GenomeRNAi human phenotype for C7orf66:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf66
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf66
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C7orf66 (NM_001024607) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C7orf66 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C7orf66 |
|
Pathways & Interactions
for C7orf66 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C7orf66
|
Drugs & Compounds
for C7orf66 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C7orf66
Search CenterWatch for drugs/clinical trials and news about C7orf66 / CG066
|
Transcripts
for C7orf66 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C7orf66 gene: NM_001024607.1 Unigene Clusters for C7orf66: Chromosome 7 open reading frame 66 Hs.276325 [show with all ESTs], Hs.638689 [show with all ESTs]Unigene Representative Sequences: BG183820, DA9305521 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000379007(uc003vfo.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf66
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf66
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C7orf66 (NM_001024607) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C7orf66 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C7orf66 |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C7orf66
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C7orf66 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C7orf66 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C7orf66 |
Additional cDNA sequence: AB063840.1 AF022010.1 AF103078.2 AJ001408.1 AJ008184.1 AJ488539.1 AY423186.1 AY423189.1 AY423190.1 AY423192.1 AY423207.1 AY866754.1 DQ100724.1 DQ100738.1 DQ100950.1 DQ379472.1 DQ523973.1 EF175386.1 EF175430.1 HM774159.1 HM995754.1 HM995755.1 HM995758.1 HM995759.1 HQ378400.1 JN110666.1 U00520.1 X79170.1 X87889.1 14 DOTS entries: DT.75125496 DT.101985804 DT.101986874 DT.101987252 DT.121508006 DT.121508087 DT.121509296 DT.121509333 DT.92039773 DT.92364395 DT.95368001 DT.97866935 DT.95248569 DT.95257989 5 AceView cDNA sequences: BG211856 BG181745 AI126292 BG200786 BG208198
GeneLoc Exon Structure
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Expression
for C7orf66 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C7orf66 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACACGGCTGT
About this image
See C7orf66 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene clusters: Hs.276325 Hs.638689
SABiosciences Custom PCR Arrays for C7orf66
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C7orf66
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C7orf66 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C7orf66 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C7orf66 |
Orthologs
for C7orf66 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for C7orf66 (if available)
TreeFam Gene Tree for C7orf66 (if available) |
Paralogs
for C7orf66 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C7orf66 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C7orf66 (108524032 - 108524644 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C7orf66: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for C7orf66 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C7orf66 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C7orf66 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C7orf66) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
- A genome-wide search for loci interacting with known p rostate cancer risk-associated genetic variants. (PubMed id 22219177)1 Tao S....Sun J. (2012)
- Large-scale genome-wide association study of Asian pop ulation reveals genetic factors in FRMD4A and other loci influencing smoking ini tiation and nicotine dependence. (PubMed id 22006218)1 Yoon D....Park T. (2012)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
- Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire. (PubMed id 9887257)1 de Wildt R.M....Winter G. (1999)
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External Searches for C7orf66 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing C7orf66 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C7orf66 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C7orf66 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C7orf66 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for C7orf66 gene:
Search GeneIP for patents involving C7orf66
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C7orf66 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C7orf66 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C7orf66 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C7orf66 | | | OriGene Protein Over-expression Lysate for C7orf66 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C7orf66 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf66 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf66 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C7orf66 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C7orf66 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C7orf66 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C7orf66 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C7orf66 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C7orf66 |
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 |  |  |  | |
| | | | Search Tocris compounds for C7orf66 |
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 | | | C7orf66 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  |  | | | | Search ThermoFisher Antibodies for C7orf66 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C7orf66 |
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