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Aliases for C7orf61 Gene

Aliases for C7orf61 Gene

  • Chromosome 7 Open Reading Frame 61 2 3 5

External Ids for C7orf61 Gene

Previous GeneCards Identifiers for C7orf61 Gene

  • GC07M099893
  • GC07M100054
  • GC07M094687

Summaries for C7orf61 Gene

GeneCards Summary for C7orf61 Gene

C7orf61 (Chromosome 7 Open Reading Frame 61) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C7orf61 Gene

Genomics for C7orf61 Gene

Regulatory Elements for C7orf61 Gene

Enhancers for C7orf61 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G100538 2 FANTOM5 Ensembl ENCODE dbSUPER 12.6 -80.3 -80343 12.6 MLX CREB3L1 AGO1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC TBX21 SAP25 PILRA IRS3P FBXO24 LRCH4 NYAP1 TSC22D4 C7orf61 ZSCAN25 PCOLCE
GH07G100560 1.3 ENCODE dbSUPER 12.1 -95.8 -95832 0.1 HDGF PKNOX1 ARNT ARID4B DMAP1 YBX1 ZNF143 FOS PAF1 SP5 NYAP1 TSC22D4 C7orf61 IRS3P AGFG2
GH07G100559 1.3 ENCODE dbSUPER 12.1 -95.7 -95672 0.2 HDGF FOXA2 PKNOX1 ARNT SIN3A ARID4B DMAP1 ZNF2 ZNF143 FOS NYAP1 TSC22D4 C7orf61 IRS3P AGFG2
GH07G100514 1.2 Ensembl ENCODE 12.7 -51.5 -51532 2.3 TBL1XR1 SIN3A ZEB1 CBX5 SCRT2 FOS RELB IKZF2 ZNF263 ZNF202 NYAP1 AP4M1 FBXO24 FAM200A PCOLCE-AS1 TSC22D4 C7orf61 ACTL6B GIGYF1 IRS3P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C7orf61 on UCSC Golden Path with GeneCards custom track

Genomic Location for C7orf61 Gene

100,456,615 bp from pter
100,464,271 bp from pter
7,657 bases
Minus strand

Genomic View for C7orf61 Gene

Genes around C7orf61 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C7orf61 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C7orf61 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C7orf61 Gene

Proteins for C7orf61 Gene

  • Protein details for C7orf61 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C7orf61
    Protein Accession:

    Protein attributes for C7orf61 Gene

    206 amino acids
    Molecular mass:
    23862 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C7orf61 Gene

Post-translational modifications for C7orf61 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C7orf61 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C7orf61 Gene

Domains & Families for C7orf61 Gene

Protein Domains for C7orf61 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C7orf61: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C7orf61 Gene

Function for C7orf61 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C7orf61 Gene

Localization for C7orf61 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C7orf61 gene
Compartment Confidence
nucleus 5
mitochondrion 3

Gene Ontology (GO) - Cellular Components for C7orf61 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 21630459
genes like me logo Genes that share ontologies with C7orf61: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C7orf61 Gene

Pathways & Interactions for C7orf61 Gene

SuperPathways for C7orf61 Gene

No Data Available

Interacting Proteins for C7orf61 Gene

Gene Ontology (GO) - Biological Process for C7orf61 Gene


No data available for Pathways by source and SIGNOR curated interactions for C7orf61 Gene

Drugs & Compounds for C7orf61 Gene

No Compound Related Data Available

Transcripts for C7orf61 Gene

mRNA/cDNA for C7orf61 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(355) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C7orf61 Gene

Chromosome 7 open reading frame 61:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C7orf61 Gene

No ASD Table

Relevant External Links for C7orf61 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C7orf61 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C7orf61 Gene

mRNA differential expression in normal tissues according to GTEx for C7orf61 Gene

This gene is overexpressed in Testis (x17.3).

Protein differential expression in normal tissues from HIPED for C7orf61 Gene

This gene is overexpressed in Testis (65.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C7orf61 Gene

Protein tissue co-expression partners for C7orf61 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C7orf61 Gene:


SOURCE GeneReport for Unigene cluster for C7orf61 Gene:


Evidence on tissue expression from TISSUES for C7orf61 Gene

  • Nervous system(2.6)
genes like me logo Genes that share expression patterns with C7orf61: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C7orf61 Gene

Orthologs for C7orf61 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C7orf61 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C7orf61 35
  • 100 (a)
C7H7orf61 34
  • 99.51 (n)
(Canis familiaris)
Mammalia C6H7orf61 34
  • 77.56 (n)
(Bos Taurus)
Mammalia C25H7orf61 34
  • 75.91 (n)
C7orf61 35
  • 64 (a)
(Rattus norvegicus)
Mammalia LOC100362783 34
  • 62.76 (n)
Species where no ortholog for C7orf61 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C7orf61 Gene

Gene Tree for C7orf61 (if available)
Gene Tree for C7orf61 (if available)

Paralogs for C7orf61 Gene

No data available for Paralogs for C7orf61 Gene

Variants for C7orf61 Gene

Sequence variations from dbSNP and Humsavar for C7orf61 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000139196 -- 100,464,315(+) CCCCG(A/T)CCCCA upstream-variant-2KB
rs1000344392 -- 100,462,850(+) CATGC(C/T)TGTAA intron-variant
rs1000621242 -- 100,456,306(+) CTGAG(C/G)CTTGG downstream-variant-500B
rs1001127552 -- 100,465,982(+) TCCCC(A/T)CTAGA upstream-variant-2KB
rs1001211671 -- 100,458,240(+) TGTGT(A/G)TAATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C7orf61 Gene

Variant ID Type Subtype PubMed ID
esv2734888 CNV deletion 23290073
nsv518432 CNV loss 19592680
nsv527050 CNV loss 19592680
nsv527107 CNV loss 19592680
nsv831071 CNV loss 17160897

Variation tolerance for C7orf61 Gene

Residual Variation Intolerance Score: 43.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.46; 9.97% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C7orf61 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C7orf61 Gene

Disorders for C7orf61 Gene

Relevant External Links for C7orf61

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C7orf61 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C7orf61 Gene

Publications for C7orf61 Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 2 3 4 64
  2. Proteomic characterization of the human sperm nucleus. (PMID: 21630459) de Mateo S. … Oliva R. (Proteomics 2011) 3 64
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for C7orf61 Gene

Sources for C7orf61 Gene

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