C7orf60 Gene
protein-coding GIFtS: 39
GCID: GC07M112459
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chromosome 7 open reading frame 60
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Aliases
for C7orf60 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 7 Open Reading Frame 601 2 | | DKFZp762M1261 | | FLJ318181 | | UPF0532 Protein C7orf602 |
Export aliases for C7orf60 gene to outside databasesPrevious GC identifers: GC07M112247 GC07M106827 |
Summaries
for C7orf60 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C7orf60 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C7orf60 gene promoter:
Pax-5 CBF-C SRY CBF-A CBF-B Sox9 CP1A CP1C NF-Y CBF(2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for C7orf60
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C7orf60 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q31.1 Ensembl cytogenetic band: 7q31.1 HGNC cytogenetic band: 7q31.1C7orf60 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07M112459: view genomic region
(about GC identifiers)
Start:
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112,459,202 bp from pter |
End:
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112,579,971 bp from pter |
Size:
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120,770 bases |
Orientation:
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minus strand |
1 alternative location:
| Chr7-,CRA_TCAG 111,827,660-111,948,430 |
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Proteins
for C7orf60 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CG060_HUMAN, Q1RMZ1 (See
protein sequence)Recommended Name: UPF0532 protein C7orf60 Size: 405 amino acids; 46324 Da
Sequence caution: Sequence=BAB71169.1; Type=Frameshift; Positions=259;
Secondary accessions: Q8N3D0 Q96MV7Explore the universe of human proteins at neXtProt for C7orf60: NX_Q1RMZ1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q1RMZ1
C7orf60 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_689769.2
ENSEMBL proteins: ENSP00000297145 ENSP00000408654
Human Recombinant Protein Products:
C7orf60 Antibody Products:
Assay Products for C7orf60: |
Protein
Domains /
Families
for C7orf60 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
C7orf60 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q1RMZ1ProtoNet protein and cluster: Q1RMZ1 UniProtKB/Swiss-Prot: CG060_HUMAN, Q1RMZ1Similarity: Belongs to the UPF0532 family |
Function
for C7orf60 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf60 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf60
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C7orf60 (NM_152556) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C7orf60 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C7orf60 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C7orf60 |
|
Pathways & Interactions
for C7orf60 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C7orf60
|
Drugs & Compounds
for C7orf60 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C7orf60
Search CenterWatch for drugs/clinical trials and news about C7orf60 / CG060
|
Transcripts
for C7orf60 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C7orf60 gene: NM_152556.2 Unigene Cluster for C7orf60: Chromosome 7 open reading frame 60 Hs.489734 [show with all ESTs]Unigene Representative Sequence: NM_1525563 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000297145(uc003vgo.1 uc011kms.1) ENST00000432572 ENST00000485446
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf60 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf60
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C7orf60 (NM_152556) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C7orf60 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C7orf60 |
Additional cDNA sequence: AF274937.1 AK056380.1 AK299901.1 AL834437.1 BC114615.1 2 DOTS entries: DT.441339 DT.121061662 24/51 AceView cDNA sequences (see all 51): AL834437 AI522064 BQ929682 CA413474 AA359228 CD721792 AI186040 BM968362 BX115096 BG213749 AI288508 AI919081 AA495938 AF274937 AW090060 BQ213362 BG613989 AI420395 AW136514 AA495937 AI097587 AW664222 AW661833 BQ003420
GeneLoc Exon Structure
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Expression
for C7orf60 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C7orf60 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGTTTTACC
About this image
See C7orf60 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C7orf60
SOURCE GeneReport for Unigene cluster: Hs.489734
SABiosciences Custom PCR Arrays for C7orf60
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C7orf60
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C7orf60 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C7orf60 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C7orf60 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C7orf60 |
Orthologs
for C7orf60 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for C7orf60 gene from 6/21 species (see all 21) About this table
ENSEMBL Gene Tree for C7orf60 (if available)
TreeFam Gene Tree for C7orf60 (if available) |
Paralogs
for C7orf60 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C7orf60 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for C7orf60 (112459202 - 112579971 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 9 variations for C7orf60
9 CNVs: 36609 8579 3699 5246 38654 82153 8578 94817 0108 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C7orf60 |
|
Disorders
/ Diseases
for C7orf60 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C7orf60 for disorders About GeneDecksing
2  diseases for C7orf60: About MalaCardsconduct disorder adhd
Human Genome Epidemiology (HuGE) Navigator: C7orf60 (1 document)
Export disorders for C7orf60 gene to outside databases
|
Publications
for C7orf60 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C7orf60 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C7orf60) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. (PubMed id 18951430)1 Anney R.J....Gill M. (2008)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for C7orf60 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing C7orf60 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C7orf60 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C7orf60 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C7orf60 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for C7orf60 gene:
Search GeneIP for patents involving C7orf60
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C7orf60 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C7orf60 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C7orf60 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C7orf60 | | | OriGene Protein Over-expression Lysate for C7orf60 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C7orf60 | | OriGene 3'-UTR Clone for C7orf60 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf60 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf60 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for C7orf60 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C7orf60 | | OriGene Custom Protein Services for C7orf60 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C7orf60 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C7orf60 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C7orf60 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C7orf60 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C7orf60 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C7orf60 |
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| | | | Search Tocris compounds for C7orf60 |
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 | | | C7orf60 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C7orf60 |
|  |  |  | | | | Search ThermoFisher Antibodies for C7orf60 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C7orf60 |
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