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Aliases for C7orf55-LUC7L2 Gene

Aliases for C7orf55-LUC7L2 Gene

  • C7orf55-LUC7L2 Readthrough 2 3
  • LUC7L2 4

External Ids for C7orf55-LUC7L2 Gene

Previous GeneCards Identifiers for C7orf55-LUC7L2 Gene

  • GC07P139031
  • GC07P139036
  • GC07P139041
  • GC07P139342

Summaries for C7orf55-LUC7L2 Gene

Entrez Gene Summary for C7orf55-LUC7L2 Gene

  • This locus represents naturally occurring readthrough transcription between the neighboring C7orf55 (chromosome 7 open reading frame 55) and LUC7L2 (LUC7-like 2) genes on chromosome 7. The readthrough transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Jul 2012]

GeneCards Summary for C7orf55-LUC7L2 Gene

C7orf55-LUC7L2 (C7orf55-LUC7L2 Readthrough) is a Protein Coding gene. GO annotations related to this gene include poly(A) RNA binding and mRNA binding. An important paralog of this gene is LUC7L2.

UniProtKB/Swiss-Prot for C7orf55-LUC7L2 Gene

  • May bind to RNA via its Arg/Ser-rich domain

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C7orf55-LUC7L2 Gene

Genomics for C7orf55-LUC7L2 Gene

Genomic Location for C7orf55-LUC7L2 Gene

139,340,359 bp from pter
139,423,457 bp from pter
83,099 bases
Plus strand

Genomic View for C7orf55-LUC7L2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for C7orf55-LUC7L2 Gene

No data available for Regulatory Elements for C7orf55-LUC7L2 Gene

Proteins for C7orf55-LUC7L2 Gene

  • Protein details for C7orf55-LUC7L2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative RNA-binding protein Luc7-like 2
    Protein Accession:
    Secondary Accessions:
    • B7Z500
    • Q8IUP9
    • Q9NVL3
    • Q9NVN7
    • Q9UQN1

    Protein attributes for C7orf55-LUC7L2 Gene

    392 amino acids
    Molecular mass:
    46514 Da
    Quaternary structure:
    • Interacts with SCNM1.
    • Interacts with SCNM1.
    • Sequence=AAD34069.1; Type=Frameshift; Positions=388; Evidence={ECO:0000305};

    Alternative splice isoforms for C7orf55-LUC7L2 Gene


neXtProt entry for C7orf55-LUC7L2 Gene

Proteomics data for C7orf55-LUC7L2 Gene at MOPED

Protein Expression for C7orf55-LUC7L2 Gene

Post-translational modifications for C7orf55-LUC7L2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C7orf55-LUC7L2 Gene

No data available for DME Specific Peptides for C7orf55-LUC7L2 Gene

Domains & Families for C7orf55-LUC7L2 Gene

Protein Domains for C7orf55-LUC7L2 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the Luc7 family.
  • Belongs to the Luc7 family.
genes like me logo Genes that share domains with C7orf55-LUC7L2: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for C7orf55-LUC7L2 Gene

Function for C7orf55-LUC7L2 Gene

Molecular function for C7orf55-LUC7L2 Gene

UniProtKB/Swiss-Prot Function:
May bind to RNA via its Arg/Ser-rich domain

Gene Ontology (GO) - Molecular Function for C7orf55-LUC7L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003729 mRNA binding --
GO:0005515 protein binding --
GO:0019899 enzyme binding --
GO:0044822 poly(A) RNA binding --
genes like me logo Genes that share ontologies with C7orf55-LUC7L2: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for C7orf55-LUC7L2 Gene

Localization for C7orf55-LUC7L2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C7orf55-LUC7L2 Gene

Nucleus speckle. Nucleus, nucleoplasm. Note=Colocalizes with SCNM1 and SNRNP70 in nuclear speckles. {ECO:0000250}.

Gene Ontology (GO) - Cellular Components for C7orf55-LUC7L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005685 U1 snRNP --
GO:0016607 nuclear speck --
genes like me logo Genes that share ontologies with C7orf55-LUC7L2: view

No data available for Subcellular locations from COMPARTMENTS for C7orf55-LUC7L2 Gene

Pathways & Interactions for C7orf55-LUC7L2 Gene

SuperPathways for C7orf55-LUC7L2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C7orf55-LUC7L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006376 mRNA splice site selection --
genes like me logo Genes that share ontologies with C7orf55-LUC7L2: view

No data available for Pathways by source and SIGNOR curated interactions for C7orf55-LUC7L2 Gene

Drugs & Compounds for C7orf55-LUC7L2 Gene

No Compound Related Data Available

Transcripts for C7orf55-LUC7L2 Gene

mRNA/cDNA for C7orf55-LUC7L2 Gene

(1) REFSEQ mRNAs :
(10) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for C7orf55-LUC7L2 Gene

No ASD Table

Relevant External Links for C7orf55-LUC7L2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C7orf55-LUC7L2 Gene

mRNA expression in normal human tissues for C7orf55-LUC7L2 Gene

Protein differential expression in normal tissues from HIPED for C7orf55-LUC7L2 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (11.1) and Heart (9.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for C7orf55-LUC7L2 Gene

genes like me logo Genes that share expression patterns with C7orf55-LUC7L2: view

Protein tissue co-expression partners for C7orf55-LUC7L2 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C7orf55-LUC7L2 Gene

Orthologs for C7orf55-LUC7L2 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for C7orf55-LUC7L2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 36
  • 81 (a)
(Canis familiaris)
Mammalia LUC7L2 36
  • 81 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 84 (a)
(Mus musculus)
Mammalia Luc7l2 36
  • 99 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 93 (a)
(Pan troglodytes)
Mammalia LUC7L2 36
  • 100 (a)
(Gallus gallus)
Aves LUC7L2 36
  • 89 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 90 (a)
(Danio rerio)
Actinopterygii C1H7orf55 36
  • 63 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG7564 36
  • 47 (a)
(Caenorhabditis elegans)
Secernentea B0495.8 36
  • 35 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes LUC7 36
  • 29 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 58 (a)
Species with no ortholog for C7orf55-LUC7L2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for C7orf55-LUC7L2 Gene

Gene Tree for C7orf55-LUC7L2 (if available)
Gene Tree for C7orf55-LUC7L2 (if available)

Paralogs for C7orf55-LUC7L2 Gene

Paralogs for C7orf55-LUC7L2 Gene

(2) SIMAP similar genes for C7orf55-LUC7L2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with C7orf55-LUC7L2: view

Variants for C7orf55-LUC7L2 Gene

Variation tolerance for C7orf55-LUC7L2 Gene

Residual Variation Intolerance Score: 22.8% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C7orf55-LUC7L2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for C7orf55-LUC7L2 Gene

Disorders for C7orf55-LUC7L2 Gene

Relevant External Links for C7orf55-LUC7L2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C7orf55-LUC7L2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C7orf55-LUC7L2 Gene

Publications for C7orf55-LUC7L2 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 67
  2. Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing. (PMID: 19574390) Webby C.J. … Boettger A. (Science 2009) 67
  3. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N. … Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67

Products for C7orf55-LUC7L2 Gene

Sources for C7orf55-LUC7L2 Gene

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