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Aliases for C7orf55 Gene

Aliases for C7orf55 Gene

  • Chromosome 7 Open Reading Frame 55 2 3 5
  • Formation Of Mitochondrial Complexes 1 Homolog (S. Cerevisiae) 2
  • Formation Of Mitochondrial Complexes 1 Homolog 3
  • HSPC268 3
  • FMC1 3

External Ids for C7orf55 Gene

Previous GeneCards Identifiers for C7orf55 Gene

  • GC07P138679
  • GC07P139024
  • GC07P133335

Summaries for C7orf55 Gene

GeneCards Summary for C7orf55 Gene

C7orf55 (Chromosome 7 Open Reading Frame 55) is a Protein Coding gene. Diseases associated with C7orf55 include splenic disease.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C7orf55 Gene

Genomics for C7orf55 Gene

Regulatory Elements for C7orf55 Gene

Promoters for C7orf55 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C7orf55 on UCSC Golden Path with GeneCards custom track

Genomic Location for C7orf55 Gene

Chromosome:
7
Start:
139,339,457 bp from pter
End:
139,346,319 bp from pter
Size:
6,863 bases
Orientation:
Plus strand

Genomic View for C7orf55 Gene

Genes around C7orf55 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C7orf55 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C7orf55 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C7orf55 Gene

Proteins for C7orf55 Gene

  • Protein details for C7orf55 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96HJ9-CG055_HUMAN
    Recommended name:
    UPF0562 protein C7orf55
    Protein Accession:
    Q96HJ9
    Secondary Accessions:
    • B7Z4Q3
    • Q75M90
    • Q9P0B3

    Protein attributes for C7orf55 Gene

    Size:
    113 amino acids
    Molecular mass:
    12749 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAF28946.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=AAF28946.1; Type=Frameshift; Positions=64; Evidence={ECO:0000305};

    Alternative splice isoforms for C7orf55 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C7orf55 Gene

Proteomics data for C7orf55 Gene at MOPED

Post-translational modifications for C7orf55 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C7orf55 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C7orf55 Gene

Domains & Families for C7orf55 Gene

Protein Domains for C7orf55 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for C7orf55 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96HJ9

UniProtKB/Swiss-Prot:

CG055_HUMAN :
  • Belongs to the UPF0562 family.
Family:
  • Belongs to the UPF0562 family.
genes like me logo Genes that share domains with C7orf55: view

No data available for Gene Families for C7orf55 Gene

Function for C7orf55 Gene

genes like me logo Genes that share phenotypes with C7orf55: view

Animal Models for C7orf55 Gene

MGI Knock Outs for C7orf55:

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for C7orf55 Gene

Localization for C7orf55 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C7orf55 Gene COMPARTMENTS Subcellular localization image for C7orf55 gene
Compartment Confidence
mitochondrion 4
cytosol 1
endoplasmic reticulum 1
nucleus 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C7orf55 Gene

Pathways & Interactions for C7orf55 Gene

SuperPathways for C7orf55 Gene

No Data Available

Interacting Proteins for C7orf55 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000297534%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000297534 for C7orf55 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for C7orf55 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C7orf55 Gene

Drugs & Compounds for C7orf55 Gene

No Compound Related Data Available

Transcripts for C7orf55 Gene

Unigene Clusters for C7orf55 Gene

Chromosome 7 open reading frame 55:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C7orf55 Gene

No ASD Table

Relevant External Links for C7orf55 Gene

GeneLoc Exon Structure for
C7orf55
ECgene alternative splicing isoforms for
C7orf55

Expression for C7orf55 Gene

mRNA expression in normal human tissues for C7orf55 Gene

Protein differential expression in normal tissues from HIPED for C7orf55 Gene

This gene is overexpressed in Adrenal (11.2), Heart (8.7), and Pancreas (7.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for C7orf55 Gene



SOURCE GeneReport for Unigene cluster for C7orf55 Gene Hs.718441

genes like me logo Genes that share expression patterns with C7orf55: view

Protein tissue co-expression partners for C7orf55 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C7orf55 Gene

Orthologs for C7orf55 Gene

This gene was present in the common ancestor of animals.

Orthologs for C7orf55 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C4H7orf55 35
  • 91.15 (n)
  • 94.69 (a)
dog
(Canis familiaris)
Mammalia C16H7orf55 35
  • 90.56 (n)
  • 92.92 (a)
mouse
(Mus musculus)
Mammalia 1110001J03Rik 35
  • 88.5 (n)
  • 92.92 (a)
1110001J03Rik 16
1110001J03Rik 36
  • 93 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia FMC1 35
  • 99.41 (n)
  • 99.12 (a)
FMC1 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fmc1 35
  • 91.15 (n)
  • 94.69 (a)
oppossum
(Monodelphis domestica)
Mammalia C7orf55 36
  • 43 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C7orf55 36
  • 83 (a)
OneToOne
chicken
(Gallus gallus)
Aves C7orf55 36
  • 79 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c7orf55 35
  • 66.06 (n)
  • 72.73 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.12989 35
zebrafish
(Danio rerio)
Actinopterygii LOC100330660 35
  • 54.74 (n)
  • 47.71 (a)
C3H7orf55 36
  • 46 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG34117 36
  • 39 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea C29E4.12 36
  • 31 (a)
OneToOne
Species with no ortholog for C7orf55:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for C7orf55 Gene

ENSEMBL:
Gene Tree for C7orf55 (if available)
TreeFam:
Gene Tree for C7orf55 (if available)

Paralogs for C7orf55 Gene

No data available for Paralogs for C7orf55 Gene

Variants for C7orf55 Gene

Sequence variations from dbSNP and Humsavar for C7orf55 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
VAR_042520 -

Structural Variations from Database of Genomic Variants (DGV) for C7orf55 Gene

Variant ID Type Subtype PubMed ID
esv2735212 CNV Deletion 23290073

Variation tolerance for C7orf55 Gene

Residual Variation Intolerance Score: 62.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 12.59; 94.49% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C7orf55 Gene

HapMap Linkage Disequilibrium report
C7orf55
Human Gene Mutation Database (HGMD)
C7orf55

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C7orf55 Gene

Disorders for C7orf55 Gene

MalaCards: The human disease database

(1) MalaCards diseases for C7orf55 Gene - From: DISEASES

Disorder Aliases PubMed IDs
splenic disease
  • dyssplenism
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for C7orf55

Genetic Association Database (GAD)
C7orf55
Human Genome Epidemiology (HuGE) Navigator
C7orf55
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C7orf55
genes like me logo Genes that share disorders with C7orf55: view

No data available for UniProtKB/Swiss-Prot and Genatlas for C7orf55 Gene

Publications for C7orf55 Gene

  1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 48 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A. … Wiemann S. (Nucleic Acids Res. 2006) 3
  5. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PMID: 16712791) Wang A.G. … Kim N.S. (Biochem. Biophys. Res. Commun. 2006) 3

Products for C7orf55 Gene

Sources for C7orf55 Gene

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