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Aliases for C7orf50 Gene

Aliases for C7orf50 Gene

  • Chromosome 7 Open Reading Frame 50 2 3 5
  • YCR016W 3

External Ids for C7orf50 Gene

Previous GeneCards Identifiers for C7orf50 Gene

  • GC07M001004
  • GC07M001036

Summaries for C7orf50 Gene

GeneCards Summary for C7orf50 Gene

C7orf50 (Chromosome 7 Open Reading Frame 50) is a Protein Coding gene. GO annotations related to this gene include poly(A) RNA binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C7orf50 Gene

Genomics for C7orf50 Gene

Regulatory Elements for C7orf50 Gene

Enhancers for C7orf50 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C7orf50 on UCSC Golden Path with GeneCards custom track

Promoters for C7orf50 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C7orf50 on UCSC Golden Path with GeneCards custom track

Genomic Location for C7orf50 Gene

978,498 bp from pter
1,138,275 bp from pter
159,778 bases
Minus strand

Genomic View for C7orf50 Gene

Genes around C7orf50 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C7orf50 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C7orf50 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C7orf50 Gene

Proteins for C7orf50 Gene

  • Protein details for C7orf50 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C7orf50
    Protein Accession:

    Protein attributes for C7orf50 Gene

    194 amino acids
    Molecular mass:
    22083 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C7orf50 Gene

Proteomics data for C7orf50 Gene at MOPED

Post-translational modifications for C7orf50 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C7orf50 Gene

Domains & Families for C7orf50 Gene

Protein Domains for C7orf50 Gene


Suggested Antigen Peptide Sequences for C7orf50 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C7orf50: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C7orf50 Gene

Function for C7orf50 Gene

Gene Ontology (GO) - Molecular Function for C7orf50 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with C7orf50: view

Phenotypes for C7orf50 Gene

GenomeRNAi human phenotypes for C7orf50:
genes like me logo Genes that share phenotypes with C7orf50: view

Animal Model Products

CRISPR Products

miRNA for C7orf50 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C7orf50 Gene

Localization for C7orf50 Gene

Subcellular locations from

Jensen Localization Image for C7orf50 Gene COMPARTMENTS Subcellular localization image for C7orf50 gene
Compartment Confidence
nucleus 4
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C7orf50 Gene

Pathways & Interactions for C7orf50 Gene

SuperPathways for C7orf50 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C7orf50 Gene


No data available for Pathways by source and SIGNOR curated interactions for C7orf50 Gene

Drugs & Compounds for C7orf50 Gene

No Compound Related Data Available

Transcripts for C7orf50 Gene

Unigene Clusters for C7orf50 Gene

Chromosome 7 open reading frame 50:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C7orf50 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c · 9d
SP1: - -
SP2: - - - - - - - -
SP3: - - -
SP4: - - - - - - - - -
SP5: - - - - - - -
SP6: -

Relevant External Links for C7orf50 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C7orf50 Gene

mRNA expression in normal human tissues for C7orf50 Gene

Protein differential expression in normal tissues from HIPED for C7orf50 Gene

This gene is overexpressed in Lung (57.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for C7orf50 Gene

SOURCE GeneReport for Unigene cluster for C7orf50 Gene Hs.653258

genes like me logo Genes that share expression patterns with C7orf50: view

Protein tissue co-expression partners for C7orf50 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C7orf50 Gene

Orthologs for C7orf50 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for C7orf50 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C25H7orf50 35
  • 76.09 (n)
  • 72.83 (a)
C25H7ORF50 36
  • 59 (a)
(Canis familiaris)
Mammalia C6H7orf50 35
  • 78.76 (n)
  • 73.06 (a)
C7orf50 36
  • 50 (a)
(Mus musculus)
Mammalia 3110082I17Rik 35
  • 73.8 (n)
  • 65.78 (a)
3110082I17Rik 16
3110082I17Rik 36
  • 63 (a)
(Pan troglodytes)
Mammalia C7H7orf50 35
  • 97.57 (n)
  • 97.35 (a)
C7orf50 36
  • 97 (a)
(Rattus norvegicus)
Mammalia LOC498154 35
  • 74.23 (n)
  • 67.03 (a)
(Ornithorhynchus anatinus)
Mammalia C7orf50 36
  • 57 (a)
(Gallus gallus)
Aves C7ORF50 35
  • 67.84 (n)
  • 62.68 (a)
C7orf50 36
  • 56 (a)
(Anolis carolinensis)
Reptilia C7orf50 36
  • 60 (a)
(Danio rerio)
Actinopterygii C7orf50 36
  • 29 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 38
Species with no ortholog for C7orf50:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C7orf50 Gene

Gene Tree for C7orf50 (if available)
Gene Tree for C7orf50 (if available)

Paralogs for C7orf50 Gene

No data available for Paralogs for C7orf50 Gene

Variants for C7orf50 Gene

Sequence variations from dbSNP and Humsavar for C7orf50 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs868832 -- 1,015,345(-) ACAAA(C/G)ACCTG intron-variant
rs868833 -- 1,015,337(-) CTGCT(C/G)GTGCC intron-variant
rs868834 -- 1,015,399(-) CAAAC(C/T)CTGTT intron-variant
rs869412 -- 1,034,498(-) CATGC(A/G)GTTCC intron-variant
rs871019 -- 1,065,594(+) TCAGC(A/G)GCTCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C7orf50 Gene

Variant ID Type Subtype PubMed ID
dgv7074n71 CNV Loss 21882294
dgv7078n71 CNV Loss 21882294
nsv887128 CNV Loss 21882294
dgv7080n71 CNV Loss 21882294
nsv509182 CNV Insertion 20534489
nsv464245 CNV Gain 19166990
nsv887140 CNV Loss 21882294
nsv887141 CNV Loss 21882294
nsv887142 CNV Gain 21882294
dgv7081n71 CNV Loss 21882294
dgv7082n71 CNV Loss 21882294
dgv7083n71 CNV Loss 21882294
nsv887149 CNV Loss 21882294
dgv7084n71 CNV Loss 21882294
dgv7085n71 CNV Loss 21882294
esv2733699 CNV Deletion 23290073
esv2733700 CNV Deletion 23290073
esv25014 CNV Loss 19812545
esv2733701 CNV Deletion 23290073
esv2733702 CNV Deletion 23290073
esv1168586 CNV Deletion 17803354
esv1257857 CNV Insertion 17803354
esv1298174 CNV Insertion 17803354
dgv7086n71 CNV Loss 21882294
nsv887158 CNV Loss 21882294
dgv7087n71 CNV Loss 21882294
esv2733703 CNV Deletion 23290073
esv2733704 CNV Deletion 23290073
esv2733705 CNV Deletion 23290073
esv2733707 CNV Deletion 23290073
esv2733708 CNV Deletion 23290073
esv2662781 CNV Deletion 23128226
nsv509183 CNV Insertion 20534489
esv2733709 CNV Deletion 23290073
nsv823959 CNV Loss 20364138
nsv823960 CNV Gain 20364138
nsv887163 CNV Loss 21882294
esv2660257 CNV Deletion 23128226
nsv482917 CNV Loss 15286789
esv28196 CNV Loss 19812545
nsv5612 CNV Insertion 18451855
nsv830876 CNV Loss 17160897
esv2733710 CNV Deletion 23290073
esv988130 CNV Deletion 20482838
esv1030117 CNV Deletion 17803354
esv2733711 CNV Deletion 23290073
esv2067416 CNV Deletion 18987734
nsv365634 CNV Loss 16902084
esv2733712 CNV Deletion 23290073
esv2741488 CNV Deletion 23290073
esv2733713 CNV Deletion 23290073
esv2733714 CNV Deletion 23290073
esv29179 CNV Gain+Loss 19812545
nsv820743 CNV Deletion 20802225
nsv8027 CNV Gain+Loss 18304495
esv2676489 CNV Deletion 23128226
esv2733715 CNV Deletion 23290073
esv2733716 CNV Deletion 23290073
nsv365945 CNV Loss 16902084
nsv522801 CNV Loss 19592680
nsv508441 CNV Loss 20534489
esv2733718 CNV Deletion 23290073
esv2398682 CNV Deletion 18987734
nsv511938 CNV Loss 21212237
dgv1108e201 CNV Deletion 23290073
esv2733720 CNV Deletion 23290073
esv2733722 CNV Deletion 23290073
esv2733724 CNV Deletion 23290073
esv2733725 CNV Deletion 23290073

Variation tolerance for C7orf50 Gene

Residual Variation Intolerance Score: 82.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.88; 48.51% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for C7orf50 Gene

Disorders for C7orf50 Gene

Relevant External Links for C7orf50

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C7orf50 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C7orf50 Gene

Publications for C7orf50 Gene

  1. Joint influence of small-effect genetic variants on human longevity. (PMID: 20834067) Yashin A.I. … Ukraintseva S.V. (Aging (Albany NY) 2010) 3 48 67
  2. Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. (PMID: 25921289) Emdal K.B. … Olsen J.V. (Sci Signal 2015) 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  5. PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry. (PMID: 24332808) Marechal A. … Zou L. (Mol. Cell 2014) 3

Products for C7orf50 Gene

Sources for C7orf50 Gene