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Aliases for C7orf34 Gene

Aliases for C7orf34 Gene

  • Chromosome 7 Open Reading Frame 34 2 3 5
  • MSSP-Binding Protein CTM-1 3 4
  • Uncharacterized Protein C7orf34 3
  • Ctm-1 3

External Ids for C7orf34 Gene

Previous GeneCards Identifiers for C7orf34 Gene

  • GC07P142030
  • GC07P142107
  • GC07P142153
  • GC07P142347
  • GC07P142636
  • GC07P136974

Summaries for C7orf34 Gene

GeneCards Summary for C7orf34 Gene

C7orf34 (Chromosome 7 Open Reading Frame 34) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C7orf34 Gene

Genomics for C7orf34 Gene

Regulatory Elements for C7orf34 Gene

Enhancers for C7orf34 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F142926 1 Ensembl ENCODE 12.5 -11.8 -11843 1.8 MAX CEBPB KEL C7orf34 EPHB6 OR6V1 OR9P1P TRBV30 TRPV5 TRPV6
GH07F142908 0.9 Ensembl ENCODE 12.2 -29.6 -29613 2.4 CTCF RFX1 ESRRA ELF1 MNT RAD21 ZNF316 SMARCA4 IKZF1 ID3 KEL TRPV5 C7orf34 EPHB6 OR9P1P OR6V1 TRPV6
GH07F142899 0.6 ENCODE 11.5 -40.2 -40235 0.2 TRPV5 C7orf34 KEL TRPV6
GH07F142866 0.7 ENCODE 10.9 -72.9 -72863 0.2 CTCF CBX3 IKZF1 SMC3 REST RAD21 TRPV5 C7orf34 KEL GC07P143501 EPHB6
GH07F142865 0.4 Ensembl 10.9 -73.5 -73543 0.8 JUND IKZF1 EPHB6 TRPV5 C7orf34 KEL GC07P143501
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C7orf34 on UCSC Golden Path with GeneCards custom track

Genomic Location for C7orf34 Gene

Chromosome:
7
Start:
142,939,343 bp from pter
End:
142,940,870 bp from pter
Size:
1,528 bases
Orientation:
Plus strand

Genomic View for C7orf34 Gene

Genes around C7orf34 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C7orf34 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C7orf34 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C7orf34 Gene

Proteins for C7orf34 Gene

  • Protein details for C7orf34 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96L11-CG034_HUMAN
    Recommended name:
    Uncharacterized protein C7orf34
    Protein Accession:
    Q96L11
    Secondary Accessions:
    • A4D2H8
    • C9JTW1
    • Q8TDV6

    Protein attributes for C7orf34 Gene

    Size:
    122 amino acids
    Molecular mass:
    13527 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C7orf34 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C7orf34 Gene

Post-translational modifications for C7orf34 Gene

No Post-translational modifications

Other Protein References for C7orf34 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C7orf34 Gene

Domains & Families for C7orf34 Gene

Protein Domains for C7orf34 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C7orf34 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C7orf34: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C7orf34 Gene

Function for C7orf34 Gene

Phenotypes for C7orf34 Gene

genes like me logo Genes that share phenotypes with C7orf34: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C7orf34 Gene

Localization for C7orf34 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C7orf34 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C7orf34 Gene COMPARTMENTS Subcellular localization image for C7orf34 gene
Compartment Confidence
extracellular 4
plasma membrane 2

Gene Ontology (GO) - Cellular Components for C7orf34 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with C7orf34: view

Pathways & Interactions for C7orf34 Gene

SuperPathways for C7orf34 Gene

No Data Available

Interacting Proteins for C7orf34 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000386450%0d%0a9606.ENSP00000366902%0d%0a
Selected Interacting proteins: ENSP00000386450 Q96L11-CG034_HUMAN for C7orf34 Gene via STRING IID

Gene Ontology (GO) - Biological Process for C7orf34 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C7orf34 Gene

Transcripts for C7orf34 Gene

mRNA/cDNA for C7orf34 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C7orf34 Gene

Chromosome 7 open reading frame 34:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C7orf34 Gene

No ASD Table

Relevant External Links for C7orf34 Gene

GeneLoc Exon Structure for
C7orf34
ECgene alternative splicing isoforms for
C7orf34

Expression for C7orf34 Gene

mRNA expression in normal human tissues for C7orf34 Gene

mRNA differential expression in normal tissues according to GTEx for C7orf34 Gene

This gene is overexpressed in Testis (x38.4) and Whole Blood (x6.5).

NURSA nuclear receptor signaling pathways regulating expression of C7orf34 Gene:

C7orf34

SOURCE GeneReport for Unigene cluster for C7orf34 Gene:

Hs.239676
genes like me logo Genes that share expression patterns with C7orf34: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C7orf34 Gene

Orthologs for C7orf34 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C7orf34 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C7H7orf34 34
  • 99.32 (n)
C7orf34 35
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C16H7orf34 34
  • 78.25 (n)
C7orf34 35
  • 53 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C4H7orf34 34
  • 75.98 (n)
C7orf34 35
  • 62 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC680112 34
  • 68.32 (n)
mouse
(Mus musculus)
Mammalia 1700034O15Rik 34 16 35
  • 65.68 (n)
oppossum
(Monodelphis domestica)
Mammalia C7orf34 35
  • 42 (a)
OneToOne
Species where no ortholog for C7orf34 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C7orf34 Gene

ENSEMBL:
Gene Tree for C7orf34 (if available)
TreeFam:
Gene Tree for C7orf34 (if available)

Paralogs for C7orf34 Gene

No data available for Paralogs for C7orf34 Gene

Variants for C7orf34 Gene

Sequence variations from dbSNP and Humsavar for C7orf34 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10259499 -- 142,938,753(+) CTCTC(A/G)CTCTC intron-variant, upstream-variant-2KB
rs1042015 -- 142,941,359(-) CTCCA(A/C)ACCTC downstream-variant-500B, reference, missense
rs10952540 -- 142,937,815(+) AGGCT(C/G)CTCCC nc-transcript-variant, upstream-variant-2KB
rs111344092 -- 142,940,735(+) GGTTC(A/G)GAGTT downstream-variant-500B, upstream-variant-2KB, utr-variant-3-prime
rs111853478 -- 142,940,517(+) TGTCA(C/T)GGTTT upstream-variant-2KB, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for C7orf34 Gene

Variant ID Type Subtype PubMed ID
esv2759569 CNV loss 17122850
nsv1030700 CNV gain 25217958
nsv520735 CNV loss 19592680
nsv526015 CNV gain 19592680
nsv831168 CNV gain 17160897

Variation tolerance for C7orf34 Gene

Residual Variation Intolerance Score: 90.7% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C7orf34 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C7orf34

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C7orf34 Gene

Disorders for C7orf34 Gene

Relevant External Links for C7orf34

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C7orf34

No disorders were found for C7orf34 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C7orf34 Gene

Publications for C7orf34 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  2. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. (PMID: 26871637) Yang X. … Vidal M. (Cell 2016) 3 64
  5. Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution. (PMID: 15790807) Cheng J. … Gingeras T.R. (Science 2005) 3 64

Products for C7orf34 Gene

Sources for C7orf34 Gene

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