C7orf34 Gene
protein-coding GIFtS: 38
GCID: GC07P142636
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chromosome 7 open reading frame 34
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Aliases
for C7orf34 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 7 Open Reading Frame 341 2 | | MSSP-Binding Protein CTM-12 3 | | CTM-11 | | Ctm-11 | | Uncharacterized Protein C7orf342 |
Export aliases for C7orf34 gene to outside databasesPrevious GC identifers: GC07P142030 GC07P142107 GC07P142153 GC07P142347 GC07P136974 |
Summaries
for C7orf34 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C7orf34 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007914.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C7orf34 gene promoter:
NF-1 Tal-1 AML1a Tal-1beta E47 HOXA5 FOXJ2 (long isoform) FOXJ2 NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for C7orf34
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C7orf34 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q34 Ensembl cytogenetic band: 7q34 HGNC cytogenetic band: 7q35C7orf34 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P142636: view genomic region
(about GC identifiers)
Start:
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142,636,440 bp from pter |
End:
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142,637,957 bp from pter |
Size:
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1,518 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 142,038,472-142,039,828 |
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Proteins
for C7orf34 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CG034_HUMAN, Q96L11 (See
protein sequence)Recommended Name: Uncharacterized protein C7orf34 precursor Size: 122 amino acids; 13527 Da
Subcellular location: Secreted (Potential)
Secondary accessions: A4D2H8 C9JTW1 Q8TDV6Alternative splicing: 2 isoforms: Q96L11-1 Q96L11-2 Explore the universe of human proteins at neXtProt for C7orf34: NX_Q96L11
C7orf34 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_849151.2
ENSEMBL proteins: ENSP00000401055 ENSP00000386450
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
IEA | -- |
C7orf34 for ontologies About GeneDecksing
C7orf34 Antibody Products:
Assay Products for C7orf34: |
Protein
Domains /
Families
for C7orf34 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q96L11 |
Function
for C7orf34 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf34 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf34 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C7orf34 (NM_178829) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C7orf34 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C7orf34 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C7orf34 |
|
Pathways & Interactions
for C7orf34 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C7orf34
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
3 Interacting proteins for C7orf34 (Q96L112, 3 ENSP000003864504) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for C7orf34 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C7orf34
Search CenterWatch for drugs/clinical trials and news about C7orf34 / CG034
|
Transcripts
for C7orf34 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C7orf34 gene: NM_178829.4 Unigene Cluster for C7orf34: Chromosome 7 open reading frame 34 Hs.239676 [show with all ESTs]Unigene Representative Sequence: AY9276252 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000458732 ENST00000409607(uc003wca.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf34 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf34 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C7orf34 (NM_178829) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C7orf34 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C7orf34 |
Additional cDNA sequence: AB083483.1 AB083484.1 AY927625.1 BC014596.1 3 DOTS entries: DT.408201 DT.97763619 DT.95263886 4 AceView cDNA sequences: AB083483 AB083484 NM_178829 BC014596
GeneLoc Exon Structure
|
Expression
for C7orf34 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C7orf34 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See C7orf34 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C7orf34
SOURCE GeneReport for Unigene cluster: Hs.239676
SABiosciences Custom PCR Arrays for C7orf34
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C7orf34
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C7orf34 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C7orf34 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C7orf34 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C7orf34 |
Orthologs
for C7orf34 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for C7orf34 gene from 1/5 species (see all 5) About this table
ENSEMBL Gene Tree for C7orf34 (if available)
TreeFam Gene Tree for C7orf34 (if available) |
Paralogs
for C7orf34 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C7orf34 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C7orf34 (142636440 - 142637957 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for C7orf34
1 CNV: 52134 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C7orf34 |
|
Disorders
/ Diseases
for C7orf34 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C7orf34 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C7orf34 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C7orf34) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (2003)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
|
External Searches for C7orf34 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing C7orf34 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C7orf34 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C7orf34 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C7orf34 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C7orf34 gene:
Search GeneIP for patents involving C7orf34
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C7orf34 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C7orf34 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C7orf34 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C7orf34 | | | OriGene Protein Over-expression Lysate for C7orf34 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C7orf34 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf34 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C7orf34 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C7orf34 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C7orf34 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C7orf34 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C7orf34 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C7orf34 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C7orf34 |
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 | | | C7orf34 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C7orf34 |
|  |  |  | | | | Search ThermoFisher Antibodies for C7orf34 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C7orf34 |
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