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Aliases for C7orf33 Gene

Aliases for C7orf33 Gene

  • Chromosome 7 Open Reading Frame 33 2 3 5

External Ids for C7orf33 Gene

Previous GeneCards Identifiers for C7orf33 Gene

  • GC07P147602
  • GC07P147679
  • GC07P147725
  • GC07P147918
  • GC07P148287
  • GC07P142368

Summaries for C7orf33 Gene

GeneCards Summary for C7orf33 Gene

C7orf33 (Chromosome 7 Open Reading Frame 33) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C7orf33 Gene

Genomics for C7orf33 Gene

Regulatory Elements for C7orf33 Gene

Enhancers for C7orf33 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G148912 1.5 Ensembl ENCODE dbSUPER 10 +323.3 323299 2.3 PKNOX1 FEZF1 TCF12 GLIS2 CBX5 FOS JUNB REST TBX21 CBX8 EZH2 C7orf33 GC07P148916 GC07M148898
GH07G148563 1.1 Ensembl ENCODE 11.5 -26.0 -25977 1.9 TBL1XR1 RAD21 ZNF335 TCF12 ZNF350 FOS RELB IKZF2 JUNB SMARCA4 ZNF783 C7orf33 ENSG00000271664 ZNF398 ZNF212 RPL32P17 GC07M148530 GC07P148581
GH07G148962 1.1 ENCODE 10.3 +373.0 373033 2.6 HDGF PKNOX1 ARNT ZFP64 ARID4B SIN3A DMAP1 YBX1 ZNF2 YY1 ZNF212 ZNF777 ZNF282 ZNF398 ENSG00000271664 ZNF786 EZH2 PDIA4 ZNF783 C7orf33
GH07G148623 0.7 ENCODE 11.1 +33.4 33419 0.2 RNF2 ZFP37 FEZF1 ZNF394 ZNF843 OSR2 PRDM6 ZNF366 ZNF629 PRDM10 C7orf33 GC07P148623 LOC105375557
GH07G148637 0.7 FANTOM5 10.7 +47.1 47067 0.4 PKNOX1 ZFP37 ZEB2 OSR2 ZNF335 ZSCAN21 ZFP69B PRDM10 MAFK PRDM1 C7orf33 GC07P148640 LOC643438
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C7orf33 on UCSC Golden Path with GeneCards custom track

Genomic Location for C7orf33 Gene

148,590,565 bp from pter
148,615,860 bp from pter
25,296 bases
Plus strand

Genomic View for C7orf33 Gene

Genes around C7orf33 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C7orf33 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C7orf33 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C7orf33 Gene

Proteins for C7orf33 Gene

  • Protein details for C7orf33 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C7orf33
    Protein Accession:

    Protein attributes for C7orf33 Gene

    177 amino acids
    Molecular mass:
    19475 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C7orf33 Gene

Post-translational modifications for C7orf33 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C7orf33 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C7orf33 Gene

Domains & Families for C7orf33 Gene

Protein Domains for C7orf33 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C7orf33: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C7orf33 Gene

Function for C7orf33 Gene

Phenotypes for C7orf33 Gene

GenomeRNAi human phenotypes for C7orf33:
genes like me logo Genes that share phenotypes with C7orf33: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C7orf33 Gene

Localization for C7orf33 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C7orf33 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C7orf33 Gene

Pathways & Interactions for C7orf33 Gene

SuperPathways for C7orf33 Gene

No Data Available

Interacting Proteins for C7orf33 Gene

Gene Ontology (GO) - Biological Process for C7orf33 Gene


No data available for Pathways by source and SIGNOR curated interactions for C7orf33 Gene

Drugs & Compounds for C7orf33 Gene

No Compound Related Data Available

Transcripts for C7orf33 Gene

mRNA/cDNA for C7orf33 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C7orf33 Gene

Chromosome 7 open reading frame 33:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C7orf33 Gene

No ASD Table

Relevant External Links for C7orf33 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C7orf33 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C7orf33 Gene

mRNA differential expression in normal tissues according to GTEx for C7orf33 Gene

This gene is overexpressed in Testis (x49.1).

NURSA nuclear receptor signaling pathways regulating expression of C7orf33 Gene:


SOURCE GeneReport for Unigene cluster for C7orf33 Gene:

genes like me logo Genes that share expression patterns with C7orf33: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C7orf33 Gene

Orthologs for C7orf33 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C7orf33 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C7H7orf33 34
  • 99.25 (n)
C7orf33 35
  • 98 (a)
Species where no ortholog for C7orf33 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C7orf33 Gene

Gene Tree for C7orf33 (if available)
Gene Tree for C7orf33 (if available)

Paralogs for C7orf33 Gene

No data available for Paralogs for C7orf33 Gene

Variants for C7orf33 Gene

Sequence variations from dbSNP and Humsavar for C7orf33 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000022594 -- 148,592,843(+) TTTTT(-/A)ATTAT intron-variant
rs1000239537 -- 148,589,526(+) AGCCC(C/T)ACCAG upstream-variant-2KB
rs1000311687 -- 148,614,405(+) TGCCT(A/G)GATGT intron-variant
rs1000398560 -- 148,596,148(+) AACTT(C/T)ATATT intron-variant
rs1000461173 -- 148,591,176(+) CAGTC(A/C)GTATC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C7orf33 Gene

Variant ID Type Subtype PubMed ID
nsv1111348 CNV tandem duplication 24896259
nsv526993 CNV gain 19592680

Variation tolerance for C7orf33 Gene

Residual Variation Intolerance Score: 77.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.44; 42.97% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C7orf33 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C7orf33 Gene

Disorders for C7orf33 Gene

Relevant External Links for C7orf33

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C7orf33 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C7orf33 Gene

Publications for C7orf33 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  2. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for C7orf33 Gene

Sources for C7orf33 Gene

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