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Aliases for C7orf31 Gene

Aliases for C7orf31 Gene

  • Chromosome 7 Open Reading Frame 31 2 3 5

External Ids for C7orf31 Gene

Previous GeneCards Identifiers for C7orf31 Gene

  • GC07M024882
  • GC07M024916
  • GC07M024947
  • GC07M025140

Summaries for C7orf31 Gene

GeneCards Summary for C7orf31 Gene

C7orf31 (Chromosome 7 Open Reading Frame 31) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C7orf31 Gene

Genomics for C7orf31 Gene

Regulatory Elements for C7orf31 Gene

Enhancers for C7orf31 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C7orf31 on UCSC Golden Path with GeneCards custom track

Promoters for C7orf31 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C7orf31 on UCSC Golden Path with GeneCards custom track

Genomic Location for C7orf31 Gene

25,125,200 bp from pter
25,180,748 bp from pter
55,549 bases
Minus strand

Genomic View for C7orf31 Gene

Genes around C7orf31 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C7orf31 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C7orf31 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C7orf31 Gene

Proteins for C7orf31 Gene

  • Protein details for C7orf31 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C7orf31
    Protein Accession:
    Secondary Accessions:
    • A4D165
    • Q6MZV8
    • Q6P989
    • Q7LE28
    • Q86XK1
    • Q8N1H5
    • Q96BN4

    Protein attributes for C7orf31 Gene

    590 amino acids
    Molecular mass:
    68464 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAP22338.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAC05255.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for C7orf31 Gene

Proteomics data for C7orf31 Gene at MOPED

Post-translational modifications for C7orf31 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C7orf31 Gene

No data available for DME Specific Peptides for C7orf31 Gene

Domains & Families for C7orf31 Gene

Protein Domains for C7orf31 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C7orf31: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C7orf31 Gene

Function for C7orf31 Gene

genes like me logo Genes that share phenotypes with C7orf31: view

Animal Model Products

CRISPR Products

miRNA for C7orf31 Gene

miRTarBase miRNAs that target C7orf31

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C7orf31 Gene

Localization for C7orf31 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C7orf31 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Subcellular locations from

Jensen Localization Image for C7orf31 Gene COMPARTMENTS Subcellular localization image for C7orf31 gene
Compartment Confidence
cytoskeleton 5
cytosol 3
nucleus 3
mitochondrion 2
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for C7orf31 Gene

Pathways & Interactions for C7orf31 Gene

SuperPathways for C7orf31 Gene

No Data Available

Interacting Proteins for C7orf31 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000283905 Q8N865-CG031_HUMAN for C7orf31 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for C7orf31 Gene


No data available for Pathways by source and SIGNOR curated interactions for C7orf31 Gene

Drugs & Compounds for C7orf31 Gene

No Compound Related Data Available

Transcripts for C7orf31 Gene

Unigene Clusters for C7orf31 Gene

Chromosome 7 open reading frame 31:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C7orf31 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
SP1: - - - -
SP2: - -
SP3: - -
SP4: - - -
SP5: -

Relevant External Links for C7orf31 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C7orf31 Gene

mRNA expression in normal human tissues for C7orf31 Gene

mRNA differential expression in normal tissues according to GTEx for C7orf31 Gene

This gene is overexpressed in Testis (x13.2).

Protein differential expression in normal tissues from HIPED for C7orf31 Gene

This gene is overexpressed in Testis (68.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C7orf31 Gene

SOURCE GeneReport for Unigene cluster for C7orf31 Gene Hs.122055

genes like me logo Genes that share expression patterns with C7orf31: view

Protein tissue co-expression partners for C7orf31 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C7orf31 Gene

Orthologs for C7orf31 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C7orf31 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C4H7orf31 35
  • 86.82 (n)
  • 83.73 (a)
C7orf31 36
  • 84 (a)
(Canis familiaris)
Mammalia C14H7orf31 35
  • 88.11 (n)
  • 84.13 (a)
C7orf31 36
  • 84 (a)
(Mus musculus)
Mammalia 4921507P07Rik 35
  • 79.76 (n)
  • 73.98 (a)
4921507P07Rik 16
4921507P07Rik 36
  • 74 (a)
(Pan troglodytes)
Mammalia C7H7orf31 35
  • 99.04 (n)
  • 98.14 (a)
C7orf31 36
  • 98 (a)
(Rattus norvegicus)
Mammalia LOC500124 35
  • 78.97 (n)
  • 72.96 (a)
(Monodelphis domestica)
Mammalia C7orf31 36
  • 52 (a)
(Ornithorhynchus anatinus)
Mammalia C7orf31 36
  • 52 (a)
(Gallus gallus)
Aves C2H7ORF31 35
  • 54.42 (n)
  • 42.75 (a)
C7orf31 36
  • 44 (a)
(Anolis carolinensis)
Reptilia C7orf31 36
  • 30 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100497526 35
  • 51.15 (n)
  • 40 (a)
Species with no ortholog for C7orf31:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C7orf31 Gene

Gene Tree for C7orf31 (if available)
Gene Tree for C7orf31 (if available)

Paralogs for C7orf31 Gene

No data available for Paralogs for C7orf31 Gene

Variants for C7orf31 Gene

Sequence variations from dbSNP and Humsavar for C7orf31 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs2717858 - 25,168,355(-) AAAGT(A/G)TGAGC reference, missense
rs12535348 - 25,155,134(+) CATGG(C/T)GCCGC intron-variant, reference, missense
rs2523072 - 25,155,046(-) GCCAA(C/G/T)CAAGG intron-variant, reference, missense
rs2285738 - 25,142,293(-) TTACC(A/G)TGAAA reference, missense
rs11980216 - 25,179,272(+) AAGCT(C/T)CCTGC reference, missense

Structural Variations from Database of Genomic Variants (DGV) for C7orf31 Gene

Variant ID Type Subtype PubMed ID
nsv7393 OTHER Inversion 18451855
nsv510075 CNV Loss 20534489

Variation tolerance for C7orf31 Gene

Residual Variation Intolerance Score: 97.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 16.81; 97.91% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for C7orf31 Gene

Disorders for C7orf31 Gene

Relevant External Links for C7orf31

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C7orf31 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C7orf31 Gene

Publications for C7orf31 Gene

  1. Proteomic analysis of mammalian sperm cells identifies new components of the centrosome. (PMID: 25074808) Firat-Karalar E.N. … Stearns T. (J. Cell Sci. 2014) 2 3 4 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for C7orf31 Gene

Sources for C7orf31 Gene