Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C7orf26 Gene

Aliases for C7orf26 Gene

  • Chromosome 7 Open Reading Frame 26 2 3 5

External Ids for C7orf26 Gene

Previous GeneCards Identifiers for C7orf26 Gene

  • GC07P006339
  • GC07P006374
  • GC07P006403
  • GC07P006596
  • GC07P006630
  • GC07P006635
  • GC07P006640
  • GC07P006644
  • GC07P006658

Summaries for C7orf26 Gene

GeneCards Summary for C7orf26 Gene

C7orf26 (Chromosome 7 Open Reading Frame 26) is a Protein Coding gene.

Additional gene information for C7orf26 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C7orf26 Gene

Genomics for C7orf26 Gene

Regulatory Elements for C7orf26 Gene

Enhancers for C7orf26 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H005591 1.8 FANTOM5 ENCODE dbSUPER 53.5 -993.9 -993916 8 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 CBX5 C7orf26 USP42 AP5Z1 TNRC18 RNF216P1 RPL22P16 ANKRD61 CCZ1 RBAK RNF216
GH07H007562 2 FANTOM5 Ensembl ENCODE dbSUPER 34.6 +977.5 977528 8 HDGF PKNOX1 FOXA2 SIN3A FEZF1 YBX1 ZNF2 YY1 ZNF143 ZNF207 ZNF12 C7orf26 ZNF316 ENSG00000272894 LOC100421597 COL28A1 RPA3 MIOS CCZ1B ENSG00000198580
GH07H006446 1.4 ENCODE dbSUPER 35.6 -140.6 -140584 4 HDGF PKNOX1 FOXA2 MLX ARNT ZFP64 ARID4B SIN3A FEZF1 ZNF2 DAGLB ZNF316 C7orf26 ZNF12 ANKRD61 USP42 ENSG00000198580 ENSG00000228010 KDELR2 PMS2
GH07H005780 1.1 ENCODE 41.2 -808.0 -808005 1 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZBTB7B ZNF207 ZNF143 C7orf26 ZNF316 TNRC18 RNF216 ZNF12 USP42 RNF216P1 ANKRD61 KDELR2 PIR40049
GH07H006481 1.1 ENCODE 31.7 -105.7 -105713 4 ATF1 FOXA2 ARID4B SIN3A DMAP1 YY1 GTF3C2 GLIS2 GATA2 ZNF143 ZNF316 C7orf26 USP42 ANKRD61 ZNF12 KDELR2 RNF216 CCZ1B GRID2IP DAGLB
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C7orf26 on UCSC Golden Path with GeneCards custom track

Promoters for C7orf26 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000208244 932 1401 PKNOX1 ATF1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZNF121 ELK1 ZNF207

Genomic Location for C7orf26 Gene

Chromosome:
7
Start:
6,589,368 bp from pter
End:
6,608,726 bp from pter
Size:
19,359 bases
Orientation:
Plus strand

Genomic View for C7orf26 Gene

Genes around C7orf26 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C7orf26 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C7orf26 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C7orf26 Gene

Proteins for C7orf26 Gene

  • Protein details for C7orf26 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96N11-CG026_HUMAN
    Recommended name:
    Uncharacterized protein C7orf26
    Protein Accession:
    Q96N11
    Secondary Accessions:
    • Q9BQ43

    Protein attributes for C7orf26 Gene

    Size:
    449 amino acids
    Molecular mass:
    50047 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C7orf26 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C7orf26 Gene

Post-translational modifications for C7orf26 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C7orf26 Gene

Domains & Families for C7orf26 Gene

Gene Families for C7orf26 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C7orf26 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C7orf26: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C7orf26 Gene

Function for C7orf26 Gene

Phenotypes From GWAS Catalog for C7orf26 Gene

genes like me logo Genes that share phenotypes with C7orf26: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C7orf26
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C7orf26 Gene

Localization for C7orf26 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C7orf26 gene
Compartment Confidence
plasma membrane 2
nucleus 2
cytosol 2
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Intermediate filaments (2)
  • Nucleoli (2)
  • Nucleus (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C7orf26 Gene

Pathways & Interactions for C7orf26 Gene

SuperPathways for C7orf26 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C7orf26 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C7orf26 Gene

Drugs & Compounds for C7orf26 Gene

No Compound Related Data Available

Transcripts for C7orf26 Gene

Unigene Clusters for C7orf26 Gene

Chromosome 7 open reading frame 26:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C7orf26
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for C7orf26 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b · 5c · 5d · 5e ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c
SP1: - - - - - - - - - -
SP2: - - - - - -
SP3: - - -
SP4: - - - -
SP5: - - -
SP6: - - -
SP7:
SP8: -
SP9:
SP10: - - -

Relevant External Links for C7orf26 Gene

GeneLoc Exon Structure for
C7orf26
ECgene alternative splicing isoforms for
C7orf26

Expression for C7orf26 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C7orf26 Gene

Protein differential expression in normal tissues from HIPED for C7orf26 Gene

This gene is overexpressed in Platelet (49.2) and CD4 Tcells (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C7orf26 Gene



Protein tissue co-expression partners for C7orf26 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C7orf26 Gene:

C7orf26

SOURCE GeneReport for Unigene cluster for C7orf26 Gene:

Hs.487511

Evidence on tissue expression from TISSUES for C7orf26 Gene

  • Intestine(3)
  • Pancreas(3)
genes like me logo Genes that share expression patterns with C7orf26: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C7orf26 Gene

Orthologs for C7orf26 Gene

This gene was present in the common ancestor of animals.

Orthologs for C7orf26 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C7orf26 34
  • 100 (a)
OneToOne
C7H7orf26 33
  • 99.63 (n)
dog
(Canis familiaris)
Mammalia C7orf26 34
  • 96 (a)
OneToOne
C6H7orf26 33
  • 91.22 (n)
cow
(Bos Taurus)
Mammalia C25H7ORF26 34
  • 93 (a)
OneToOne
C25H7orf26 33
  • 88.52 (n)
rat
(Rattus norvegicus)
Mammalia LOC683674 33
  • 88.47 (n)
mouse
(Mus musculus)
Mammalia E130309D02Rik 33 16 34
  • 88.1 (n)
oppossum
(Monodelphis domestica)
Mammalia C7orf26 34
  • 84 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C7orf26 34
  • 77 (a)
OneToOne
chicken
(Gallus gallus)
Aves C7orf26 34
  • 84 (a)
OneToOne
C7ORF26 33
  • 79.36 (n)
lizard
(Anolis carolinensis)
Reptilia C7orf26 34
  • 70 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c7orf26 33
  • 70.11 (n)
Str.18839 33
African clawed frog
(Xenopus laevis)
Amphibia MGC69165 33
zebrafish
(Danio rerio)
Actinopterygii zgc:56409 33
  • 63.78 (n)
C1H7orf26 34
  • 58 (a)
OneToOne
zgc56409 33
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001655 33
  • 47.51 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG5274 33 34
  • 46.33 (n)
Species where no ortholog for C7orf26 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C7orf26 Gene

ENSEMBL:
Gene Tree for C7orf26 (if available)
TreeFam:
Gene Tree for C7orf26 (if available)

Paralogs for C7orf26 Gene

No data available for Paralogs for C7orf26 Gene

Variants for C7orf26 Gene

Sequence variations from dbSNP and Humsavar for C7orf26 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000049522 -- 6,599,365(+) CAGCC(A/C)GATCA intron-variant
rs1000133121 -- 6,596,493(+) CTTTC(C/G)TCAGC intron-variant
rs1000196336 -- 6,591,045(+) TGTTA(C/G)CCAGG intron-variant
rs1000314922 -- 6,590,875(+) ACTAC(A/G)TTGCC intron-variant
rs1000343281 -- 6,604,291(+) AACTA(A/G)CAAAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C7orf26 Gene

Variant ID Type Subtype PubMed ID
dgv1090n67 CNV gain 20364138
dgv11172n54 CNV loss 21841781
dgv11173n54 CNV loss 21841781
esv1914954 OTHER inversion 16254605
esv2733932 CNV deletion 23290073
esv2733933 CNV deletion 23290073
nsv1020236 CNV gain 25217958
nsv436904 CNV insertion 17901297
nsv508444 CNV deletion 20534489
nsv515978 CNV loss 19592680
nsv606003 CNV loss 21841781
nsv7392 OTHER inversion 18451855
nsv830895 CNV loss 17160897
nsv950804 CNV deletion 24416366

Variation tolerance for C7orf26 Gene

Residual Variation Intolerance Score: 18.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.89; 48.57% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C7orf26 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C7orf26

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C7orf26 Gene

Disorders for C7orf26 Gene

Relevant External Links for C7orf26

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C7orf26

No disorders were found for C7orf26 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C7orf26 Gene

Publications for C7orf26 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  3. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C … Emili A (Nature 2015) 3 60
  4. Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF). (PMID: 21907836) Zhao J … Yang P (Journal of proteomics 2011) 3 60
  5. Streamlined analysis schema for high-throughput identification of endogenous protein complexes. (PMID: 20133760) Malovannaya A … Qin J (Proceedings of the National Academy of Sciences of the United States of America 2010) 3 60

Products for C7orf26 Gene

Sources for C7orf26 Gene

Content
Loading form....