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Aliases for C7orf26 Gene

Aliases for C7orf26 Gene

  • Chromosome 7 Open Reading Frame 26 2 3 5

External Ids for C7orf26 Gene

Previous GeneCards Identifiers for C7orf26 Gene

  • GC07P006339
  • GC07P006374
  • GC07P006403
  • GC07P006596
  • GC07P006630
  • GC07P006635
  • GC07P006640
  • GC07P006644
  • GC07P006658

Summaries for C7orf26 Gene

GeneCards Summary for C7orf26 Gene

C7orf26 (Chromosome 7 Open Reading Frame 26) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C7orf26 Gene

Genomics for C7orf26 Gene

Regulatory Elements for C7orf26 Gene

Promoters for C7orf26 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C7orf26 on UCSC Golden Path with GeneCards custom track

Genomic Location for C7orf26 Gene

Chromosome:
7
Start:
6,589,368 bp from pter
End:
6,608,726 bp from pter
Size:
19,359 bases
Orientation:
Plus strand

Genomic View for C7orf26 Gene

Genes around C7orf26 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C7orf26 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C7orf26 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C7orf26 Gene

Proteins for C7orf26 Gene

  • Protein details for C7orf26 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96N11-CG026_HUMAN
    Recommended name:
    Uncharacterized protein C7orf26
    Protein Accession:
    Q96N11
    Secondary Accessions:
    • Q9BQ43

    Protein attributes for C7orf26 Gene

    Size:
    449 amino acids
    Molecular mass:
    50047 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C7orf26 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C7orf26 Gene

Proteomics data for C7orf26 Gene at MOPED

Post-translational modifications for C7orf26 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C7orf26 Gene

No data available for DME Specific Peptides for C7orf26 Gene

Domains & Families for C7orf26 Gene

Protein Domains for C7orf26 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C7orf26: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C7orf26 Gene

Function for C7orf26 Gene

genes like me logo Genes that share phenotypes with C7orf26: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C7orf26 Gene

Localization for C7orf26 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C7orf26 Gene COMPARTMENTS Subcellular localization image for C7orf26 gene
Compartment Confidence
cytosol 2
nucleus 2
plasma membrane 2
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C7orf26 Gene

Pathways & Interactions for C7orf26 Gene

SuperPathways for C7orf26 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C7orf26 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C7orf26 Gene

Drugs & Compounds for C7orf26 Gene

No Compound Related Data Available

Transcripts for C7orf26 Gene

Unigene Clusters for C7orf26 Gene

Chromosome 7 open reading frame 26:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C7orf26 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b · 5c · 5d · 5e ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c
SP1: - - - - - - - - - -
SP2: - - - - - -
SP3: - - -
SP4: - - - -
SP5: - - -
SP6: - - -
SP7:
SP8: -
SP9:
SP10: - - -

Relevant External Links for C7orf26 Gene

GeneLoc Exon Structure for
C7orf26
ECgene alternative splicing isoforms for
C7orf26

Expression for C7orf26 Gene

mRNA expression in normal human tissues for C7orf26 Gene

Protein differential expression in normal tissues from HIPED for C7orf26 Gene

This gene is overexpressed in Platelet (49.2) and CD4 Tcells (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for C7orf26 Gene



SOURCE GeneReport for Unigene cluster for C7orf26 Gene Hs.487511

genes like me logo Genes that share expression patterns with C7orf26: view

Protein tissue co-expression partners for C7orf26 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C7orf26 Gene

Orthologs for C7orf26 Gene

This gene was present in the common ancestor of animals.

Orthologs for C7orf26 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C7orf26 36
  • 100 (a)
OneToOne
C7H7orf26 35
  • 99.63 (n)
  • 100 (a)
cow
(Bos Taurus)
Mammalia C25H7orf26 35
  • 88.52 (n)
  • 93.51 (a)
C25H7ORF26 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C7orf26 36
  • 96 (a)
OneToOne
C6H7orf26 35
  • 91.22 (n)
  • 96.21 (a)
mouse
(Mus musculus)
Mammalia E130309D02Rik 36
  • 95 (a)
OneToOne
E130309D02Rik 16
E130309D02Rik 35
  • 88.1 (n)
  • 94.87 (a)
oppossum
(Monodelphis domestica)
Mammalia C7orf26 36
  • 84 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C7orf26 36
  • 77 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC683674 35
  • 88.47 (n)
  • 94.87 (a)
chicken
(Gallus gallus)
Aves C7ORF26 35
  • 79.36 (n)
  • 88.42 (a)
C7orf26 36
  • 84 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C7orf26 36
  • 70 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia MGC69165 35
tropical clawed frog
(Silurana tropicalis)
Amphibia c7orf26 35
  • 70.11 (n)
  • 76.78 (a)
Str.18839 35
zebrafish
(Danio rerio)
Actinopterygii zgc56409 35
zgc:56409 35
  • 63.78 (n)
  • 62.87 (a)
C1H7orf26 36
  • 58 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001655 35
  • 47.51 (n)
  • 37.34 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG5274 35
  • 46.33 (n)
  • 36 (a)
CG5274 36
  • 30 (a)
OneToOne
Species with no ortholog for C7orf26:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C7orf26 Gene

ENSEMBL:
Gene Tree for C7orf26 (if available)
TreeFam:
Gene Tree for C7orf26 (if available)

Paralogs for C7orf26 Gene

No data available for Paralogs for C7orf26 Gene

Variants for C7orf26 Gene

Sequence variations from dbSNP and Humsavar for C7orf26 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs35534502 - 6,599,981(-) CCAGC(A/G)GATCA intron-variant, nc-transcript-variant, reference, missense
rs4416743 -- 6,608,107(+) ACGCA(A/C/T)CCCGG downstream-variant-500B, reference, synonymous-codon, missense
rs4418238 -- 6,604,033(+) AATGC(A/G)CTTAA intron-variant
rs4724826 -- 6,601,106(+) ggact(A/G)caagt intron-variant
rs4724827 -- 6,605,650(+) CCTGG(C/T)ACTGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C7orf26 Gene

Variant ID Type Subtype PubMed ID
nsv436904 CNV Insertion 17901297
nsv7392 OTHER Inversion 18451855
esv1914954 OTHER Inversion 16254605
nsv830895 CNV Loss 17160897
dgv7147n71 CNV Loss 21882294
nsv508444 CNV Loss 20534489
nsv515978 CNV Loss 19592680
dgv7148n71 CNV Loss 21882294
dgv7149n71 CNV Loss 21882294
dgv1090n67 CNV Gain 20364138
esv2733932 CNV Deletion 23290073
esv2733933 CNV Deletion 23290073
dgv7150n71 CNV Loss 21882294

Variation tolerance for C7orf26 Gene

Residual Variation Intolerance Score: 18.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.89; 48.57% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C7orf26 Gene

HapMap Linkage Disequilibrium report
C7orf26

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C7orf26 Gene

Disorders for C7orf26 Gene

Relevant External Links for C7orf26

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C7orf26

No disorders were found for C7orf26 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C7orf26 Gene

Publications for C7orf26 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  3. Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF). (PMID: 21907836) Zhao J. … Yang P. (J Proteomics 2011) 3
  4. Streamlined analysis schema for high-throughput identification of endogenous protein complexes. (PMID: 20133760) Malovannaya A. … Qin J. (Proc. Natl. Acad. Sci. U.S.A. 2010) 3
  5. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3

Products for C7orf26 Gene

Sources for C7orf26 Gene

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