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Aliases for C6orf62 Gene

Aliases for C6orf62 Gene

  • Chromosome 6 Open Reading Frame 62 2 3 5
  • HBV X-Transactivated Gene 12 Protein 3 4
  • HBV XAg-Transactivated Protein 12 3 4
  • HBV X-Transactivated Protein 12 2 3
  • XTP12 3 4
  • Uncharacterized Protein C6orf62 3
  • Nbla00237 3
  • DJ30M3.2 3

External Ids for C6orf62 Gene

Previous GeneCards Identifiers for C6orf62 Gene

  • GC06M024767
  • GC06M024813
  • GC06M024705

Summaries for C6orf62 Gene

GeneCards Summary for C6orf62 Gene

C6orf62 (Chromosome 6 Open Reading Frame 62) is a Protein Coding gene.

Additional gene information for C6orf62 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf62 Gene

Genomics for C6orf62 Gene

Regulatory Elements for C6orf62 Gene

Enhancers for C6orf62 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06H024657 2 FANTOM5 Ensembl ENCODE dbSUPER 23.4 +57.1 57083 11 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC ZC3H11A MEF2D SSRP1 C6orf62 TDP2 KIAA0319 NUP50P2 ACOT13 ENSG00000282804
GH06H024716 1.5 ENCODE dbSUPER 23.9 +0.9 917 5 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 SP3 NFYC C6orf62 TDP2 ACOT13 ENSG00000223623 ENSG00000230372 LOC101928663 SPTLC1P2 ENSG00000272402 KIAA0319
GH06H024770 0.9 ENCODE 24.3 -50.7 -50672 1 ELF3 FOXA2 MLX ARID4B DMAP1 RAD21 THRB ZSCAN9 RARA ATF7 C6orf62 GMNN ENSG00000272402 LOC100289381
GH06H024742 1.6 FANTOM5 Ensembl ENCODE 12.9 -22.7 -22710 2 HDAC1 TBP PKNOX1 BATF YY1 ZNF766 GATA2 SCRT2 RCOR1 FOS C6orf62 GMNN KIAA0319 TDP2 KRT8P43 LOC105374978 LOC100289381
GH06H024672 0.8 ENCODE dbSUPER 19.9 +48.0 47991 0 PKNOX1 JUND ATF3 HNF4A C6orf62 ACOT13 ENSG00000272345
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C6orf62 on UCSC Golden Path with GeneCards custom track

Promoters for C6orf62 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000194790 1036 4401 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 SP3 NFYC

Genomic Location for C6orf62 Gene

Chromosome:
6
Start:
24,704,861 bp from pter
End:
24,720,836 bp from pter
Size:
15,976 bases
Orientation:
Minus strand

Genomic View for C6orf62 Gene

Genes around C6orf62 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C6orf62 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C6orf62 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C6orf62 Gene

Proteins for C6orf62 Gene

  • Protein details for C6orf62 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9GZU0-CF062_HUMAN
    Recommended name:
    Uncharacterized protein C6orf62
    Protein Accession:
    Q9GZU0
    Secondary Accessions:
    • Q3LIB6
    • Q5JVZ2
    • Q5JVZ3
    • Q6IA63
    • Q9H1Z2

    Protein attributes for C6orf62 Gene

    Size:
    229 amino acids
    Molecular mass:
    27083 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C6orf62 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C6orf62 Gene

Post-translational modifications for C6orf62 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C6orf62 Gene

No data available for DME Specific Peptides for C6orf62 Gene

Domains & Families for C6orf62 Gene

Gene Families for C6orf62 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C6orf62 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C6orf62 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C6orf62: view

No data available for UniProtKB/Swiss-Prot for C6orf62 Gene

Function for C6orf62 Gene

Phenotypes From GWAS Catalog for C6orf62 Gene

Gene Ontology (GO) - Molecular Function for C6orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with C6orf62: view

Phenotypes for C6orf62 Gene

genes like me logo Genes that share phenotypes with C6orf62: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C6orf62
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C6orf62 Gene

Localization for C6orf62 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C6orf62 gene
Compartment Confidence
cytosol 3
nucleus 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for C6orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IDA --
genes like me logo Genes that share ontologies with C6orf62: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C6orf62 Gene

Pathways & Interactions for C6orf62 Gene

SuperPathways for C6orf62 Gene

No Data Available

Interacting Proteins for C6orf62 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://version10.5.string-db.org/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000367359%0d%0a9606.ENSP00000356991%0d%0a
Selected Interacting proteins: ENSP00000367359 Q9GZU0-CF062_HUMAN for C6orf62 Gene via STRING IID

Gene Ontology (GO) - Biological Process for C6orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with C6orf62: view

No data available for Pathways by source and SIGNOR curated interactions for C6orf62 Gene

Drugs & Compounds for C6orf62 Gene

No Compound Related Data Available

Transcripts for C6orf62 Gene

mRNA/cDNA for C6orf62 Gene

Unigene Clusters for C6orf62 Gene

Chromosome 6 open reading frame 62:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C6orf62
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for C6orf62 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c
SP1: -
SP2: - - -
SP3: - -
SP4:

Relevant External Links for C6orf62 Gene

GeneLoc Exon Structure for
C6orf62
ECgene alternative splicing isoforms for
C6orf62

Expression for C6orf62 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C6orf62 Gene

Protein differential expression in normal tissues from HIPED for C6orf62 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C6orf62 Gene



Protein tissue co-expression partners for C6orf62 Gene

NURSA nuclear receptor signaling pathways regulating expression of C6orf62 Gene:

C6orf62

SOURCE GeneReport for Unigene cluster for C6orf62 Gene:

Hs.744857

Evidence on tissue expression from TISSUES for C6orf62 Gene

  • Nervous system(4.6)
  • Spleen(2.2)
  • Thyroid gland(2)
genes like me logo Genes that share expression patterns with C6orf62: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C6orf62 Gene

Orthologs for C6orf62 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C6orf62 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C6orf62 34
  • 100 (a)
OneToOne
C6H6orf62 33
  • 99.71 (n)
cow
(Bos Taurus)
Mammalia C23H6ORF62 34
  • 99 (a)
OneToOne
C23H6orf62 33
  • 96.65 (n)
dog
(Canis familiaris)
Mammalia C6orf62 34
  • 99 (a)
OneToOne
C35H6orf62 33
  • 98.11 (n)
oppossum
(Monodelphis domestica)
Mammalia C6orf62 34
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia BC005537 33 16 34
  • 96.22 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia C6orf62 34
  • 90 (a)
OneToOne
chicken
(Gallus gallus)
Aves C6orf62 34
  • 98 (a)
OneToOne
C2H6ORF62 33
  • 92.43 (n)
lizard
(Anolis carolinensis)
Reptilia C6orf62 34
  • 96 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c6orf62 33
  • 84.28 (n)
Str.7520 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.24169 33
zebrafish
(Danio rerio)
Actinopterygii C19H6orf62 34
  • 87 (a)
OneToOne
zgc:111986 33
  • 79.77 (n)
wufb59h04 33
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 37 (a)
OneToOne
Species where no ortholog for C6orf62 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C6orf62 Gene

ENSEMBL:
Gene Tree for C6orf62 (if available)
TreeFam:
Gene Tree for C6orf62 (if available)

Paralogs for C6orf62 Gene

No data available for Paralogs for C6orf62 Gene

Variants for C6orf62 Gene

Sequence variations from dbSNP and Humsavar for C6orf62 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000037437 -- 24,719,046(+) TGTGC(A/G)ATAAA intron-variant, utr-variant-5-prime
rs1000086319 -- 24,708,332(+) GGCCT(A/G)GGAAA intron-variant
rs1000099569 -- 24,712,177(+) GTCAA(C/G)GACAC intron-variant
rs1000377376 -- 24,715,113(+) AATAT(A/G)AATCA intron-variant
rs1000518978 -- 24,708,292(+) TAACA(C/T)GCAGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C6orf62 Gene

Variant ID Type Subtype PubMed ID
nsv515732 CNV loss 19592680
nsv830609 CNV gain 17160897

Variation tolerance for C6orf62 Gene

Residual Variation Intolerance Score: 30.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.42; 9.28% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C6orf62 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C6orf62

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf62 Gene

Disorders for C6orf62 Gene

Relevant External Links for C6orf62

Genetic Association Database (GAD)
C6orf62
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C6orf62

No disorders were found for C6orf62 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C6orf62 Gene

Publications for C6orf62 Gene

  1. Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S … Poustka A (Genome research 2001) 2 3 4 60
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  4. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall AJ … Beck S (Nature 2003) 3 4 60
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60

Products for C6orf62 Gene

Sources for C6orf62 Gene

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