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Aliases for C6orf62 Gene

Aliases for C6orf62 Gene

  • Chromosome 6 Open Reading Frame 62 2 3 5
  • HBV X-Transactivated Gene 12 Protein 3 4
  • HBV XAg-Transactivated Protein 12 3 4
  • HBV X-Transactivated Protein 12 2 3
  • XTP12 3 4
  • Uncharacterized Protein C6orf62 3
  • Nbla00237 3
  • DJ30M3.2 3

External Ids for C6orf62 Gene

Previous GeneCards Identifiers for C6orf62 Gene

  • GC06M024767
  • GC06M024813
  • GC06M024705

Summaries for C6orf62 Gene

GeneCards Summary for C6orf62 Gene

C6orf62 (Chromosome 6 Open Reading Frame 62) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf62 Gene

Genomics for C6orf62 Gene

Regulatory Elements for C6orf62 Gene

Enhancers for C6orf62 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F024657 1.8 FANTOM5 Ensembl ENCODE 23.3 +57.1 57083 11.6 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 C6orf62 NUP50P2 TDP2 KIAA0319 ACOT13
GH06F024716 1.2 ENCODE 23.9 +0.9 917 5.8 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 SP3 C6orf62 TDP2 ENSG00000223623 ENSG00000230372 LOC101928663 SPTLC1P2 ACOT13 ENSG00000272402 KIAA0319
GH06F024770 0.9 ENCODE 24.3 -50.7 -50672 1.6 ELF3 ATF1 MLX ARID4B DMAP1 THRB RAD21 ZSCAN9 RARA CREM C6orf62 GMNN ENSG00000272402 LOC100289381
GH06F024742 1.3 FANTOM5 ENCODE 12.8 -22.7 -22710 2.6 TBP HDAC1 PKNOX1 NFRKB YY1 ZNF335 ZNF766 GATA2 SCRT2 RCOR1 C6orf62 GMNN KIAA0319 TDP2 KRT8P43 LOC105374978 LOC100289381
GH06F024778 1.2 Ensembl ENCODE 12.1 -58.6 -58643 1.3 ELF3 TBP MLX ARID4B RAD21 YY1 RARA FOS MIXL1 TBX21 C6orf62 NUP50P2 GMNN C6orf229
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C6orf62 on UCSC Golden Path with GeneCards custom track

Promoters for C6orf62 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001494108 1136 5401 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 SP3

Genomic Location for C6orf62 Gene

Chromosome:
6
Start:
24,704,861 bp from pter
End:
24,720,836 bp from pter
Size:
15,976 bases
Orientation:
Minus strand

Genomic View for C6orf62 Gene

Genes around C6orf62 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C6orf62 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C6orf62 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C6orf62 Gene

Proteins for C6orf62 Gene

  • Protein details for C6orf62 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9GZU0-CF062_HUMAN
    Recommended name:
    Uncharacterized protein C6orf62
    Protein Accession:
    Q9GZU0
    Secondary Accessions:
    • Q3LIB6
    • Q5JVZ2
    • Q5JVZ3
    • Q6IA63
    • Q9H1Z2

    Protein attributes for C6orf62 Gene

    Size:
    229 amino acids
    Molecular mass:
    27083 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C6orf62 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C6orf62 Gene

Post-translational modifications for C6orf62 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C6orf62 Gene

No data available for DME Specific Peptides for C6orf62 Gene

Domains & Families for C6orf62 Gene

Protein Domains for C6orf62 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C6orf62 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C6orf62: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C6orf62 Gene

Function for C6orf62 Gene

Gene Ontology (GO) - Molecular Function for C6orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with C6orf62: view

Phenotypes for C6orf62 Gene

genes like me logo Genes that share phenotypes with C6orf62: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C6orf62 Gene

Localization for C6orf62 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C6orf62 gene
Compartment Confidence
cytosol 3
nucleus 2

Gene Ontology (GO) - Cellular Components for C6orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IDA --
genes like me logo Genes that share ontologies with C6orf62: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C6orf62 Gene

Pathways & Interactions for C6orf62 Gene

SuperPathways for C6orf62 Gene

No Data Available

Interacting Proteins for C6orf62 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000367359%0d%0a9606.ENSP00000385269%0d%0a9606.ENSP00000377411%0d%0a
Selected Interacting proteins: Q9GZU0-CF062_HUMAN ENSP00000367359 for C6orf62 Gene via IID STRING

Gene Ontology (GO) - Biological Process for C6orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with C6orf62: view

No data available for Pathways by source and SIGNOR curated interactions for C6orf62 Gene

Transcripts for C6orf62 Gene

mRNA/cDNA for C6orf62 Gene

Unigene Clusters for C6orf62 Gene

Chromosome 6 open reading frame 62:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C6orf62 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c
SP1: -
SP2: - - -
SP3: - -
SP4:

Relevant External Links for C6orf62 Gene

GeneLoc Exon Structure for
C6orf62
ECgene alternative splicing isoforms for
C6orf62

Expression for C6orf62 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C6orf62 Gene

Protein differential expression in normal tissues from HIPED for C6orf62 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C6orf62 Gene



Protein tissue co-expression partners for C6orf62 Gene

NURSA nuclear receptor signaling pathways regulating expression of C6orf62 Gene:

C6orf62

SOURCE GeneReport for Unigene cluster for C6orf62 Gene:

Hs.744857
genes like me logo Genes that share expression patterns with C6orf62: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C6orf62 Gene

Orthologs for C6orf62 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C6orf62 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C6orf62 35
  • 100 (a)
OneToOne
C6H6orf62 34
  • 99.71 (n)
cow
(Bos Taurus)
Mammalia C23H6ORF62 35
  • 99 (a)
OneToOne
C23H6orf62 34
  • 96.65 (n)
dog
(Canis familiaris)
Mammalia C6orf62 35
  • 99 (a)
OneToOne
C35H6orf62 34
  • 98.11 (n)
oppossum
(Monodelphis domestica)
Mammalia C6orf62 35
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia BC005537 34 16 35
  • 96.22 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia C6orf62 35
  • 90 (a)
OneToOne
chicken
(Gallus gallus)
Aves C6orf62 35
  • 98 (a)
OneToOne
C2H6ORF62 34
  • 92.43 (n)
lizard
(Anolis carolinensis)
Reptilia C6orf62 35
  • 96 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c6orf62 34
  • 84.28 (n)
Str.7520 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.24169 34
zebrafish
(Danio rerio)
Actinopterygii C19H6orf62 35
  • 87 (a)
OneToOne
zgc:111986 34
  • 79.77 (n)
wufb59h04 34
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 37 (a)
OneToOne
Species where no ortholog for C6orf62 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C6orf62 Gene

ENSEMBL:
Gene Tree for C6orf62 (if available)
TreeFam:
Gene Tree for C6orf62 (if available)

Paralogs for C6orf62 Gene

No data available for Paralogs for C6orf62 Gene

Variants for C6orf62 Gene

Sequence variations from dbSNP and Humsavar for C6orf62 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs10456316 -- 24,710,801(+) TGAGA(A/C)CAGCC intron-variant
rs1053597 -- 24,704,512(-) AAATA(G/T)ATGCa intron-variant, downstream-variant-500B, utr-variant-3-prime
rs1053598 -- 24,704,310(+) TCTGG(C/T)AACTT downstream-variant-500B, utr-variant-3-prime
rs10574302 -- 24,712,691(+) GTCTC(-/A)AAAAA intron-variant
rs1065364 -- 24,710,172(-) AGTAT(A/G)ATAAG intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for C6orf62 Gene

Variant ID Type Subtype PubMed ID
nsv515732 CNV loss 19592680
nsv830609 CNV gain 17160897

Variation tolerance for C6orf62 Gene

Residual Variation Intolerance Score: 30.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.42; 9.28% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C6orf62 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C6orf62

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf62 Gene

Disorders for C6orf62 Gene

Relevant External Links for C6orf62

Genetic Association Database (GAD)
C6orf62
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C6orf62

No disorders were found for C6orf62 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C6orf62 Gene

Publications for C6orf62 Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4 64
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64

Products for C6orf62 Gene

Sources for C6orf62 Gene

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