C6orf62 Gene
protein-coding GIFtS: 44
GCID: GC06M024654
|
|
chromosome 6 open reading frame 62
| |
Aliases
for C6orf62 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 6 Open Reading Frame 621 2 | | FLJ126191 | | XTP121 2 3 | | Nbla002372 | | HBV X-Transactivated Gene 12 Protein2 3 | | DJ30M3.21 | | HBV XAg-Transactivated Protein 122 3 | | HBV X-Transactivated Protein 122 | | DKFZP564G1821 | | Uncharacterized Protein C6orf622 |
Export aliases for C6orf62 gene to outside databasesPrevious GC identifers: GC06M024767 GC06M024813 GC06M024705 |
Summaries
for C6orf62 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C6orf62 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C6orf62 gene promoter:
AML1a Sp1 ATF-2 AP-2gamma HNF-1A Gfi-1 CRE-BP1 POU2F1a ARP-1 En-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for C6orf62
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C6orf62 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p22.3 Ensembl cytogenetic band: 6p22.3 HGNC cytogenetic band: 6p22.1C6orf62 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M024654: view genomic region
(about GC identifiers)
Start:
|
24,705,089 bp from pter |
End:
|
24,721,064 bp from pter |
Size:
|
15,976 bases |
Orientation:
|
minus strand |
|
Proteins
for C6orf62 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CF062_HUMAN, Q9GZU0 (See
protein sequence)Recommended Name: Uncharacterized protein C6orf62 Size: 229 amino acids; 27083 Da
Secondary accessions: Q3LIB6 Q5JVZ2 Q5JVZ3 Q6IA63 Q9H1Z2Alternative splicing: 2 isoforms: Q9GZU0-1 Q9GZU0-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for C6orf62: NX_Q9GZU0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9GZU0
C6orf62 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_112201.1
ENSEMBL proteins: ENSP00000367359 ENSP00000367342 ENSP00000446225
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005622 | intracellular |
IDA | -- |
C6orf62 for ontologies About GeneDecksing
C6orf62 Antibody Products:
Assay Products for C6orf62: |
Protein
Domains /
Families
for C6orf62 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
C6orf62 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9GZU0ProtoNet protein and cluster: Q9GZU0 |
Function
for C6orf62 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf62 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf62
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C6orf62 (NM_030939) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C6orf62 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C6orf62 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C6orf62 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- |
C6orf62 for ontologies About GeneDecksing
|
Pathways & Interactions
for C6orf62 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C6orf62
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
2 Interacting proteins for C6orf62 (Q9GZU03 ENSP000003673594) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- |
C6orf62 for ontologies About GeneDecksing
|
Drugs & Compounds
for C6orf62 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C6orf62
Search CenterWatch for drugs/clinical trials and news about C6orf62 / CF062
|
Transcripts
for C6orf62 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C6orf62 gene: NM_030939.4 Unigene Cluster for C6orf62: Chromosome 6 open reading frame 62 Hs.9676 [show with all ESTs]Unigene Representative Sequence: NM_0309394 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000378119(uc003nel.3) ENST00000465685 ENST00000378102 ENST00000540769
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf62 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf62
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C6orf62 (NM_030939) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C6orf62 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C6orf62 |
Additional cDNA sequence: AB075502.1 AJ420475.1 AK022681.1 AK301718.1 AL136632.2 AY598792.1 BC040260.1 BC047866.1 CR457292.1 CR533486.1 22 DOTS entries: DT.451942 DT.91958549 DT.92462145 DT.91754092 DT.121363951 DT.91656356 DT.100818327 DT.100818328 DT.100033275 DT.92462158 DT.86854517 DT.91697820 DT.95287994 DT.100818325 DT.121363899 DT.121363978 DT.121363993 DT.95241436 DT.95306742 DT.121363971 DT.85104188 DT.95241428 24/493 AceView cDNA sequences (see all 493): BX479627 BQ434599 AA830534 AA370915 AA830274 C01428 BF111215 BF218075 BU733961 AA974142 BF109576 AV709526 BG655426 BE178693 AV656408 CF144349 AA912273 AA554017 CA314456 BQ428034 AU138364 AV703346 CB110902 BI020708
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for C6orf62 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | - | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for C6orf62
|
Expression
for C6orf62 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C6orf62 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATAGGTAGAG
About this image
See C6orf62 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C6orf62
SOURCE GeneReport for Unigene cluster: Hs.9676
SABiosciences Custom PCR Arrays for C6orf62
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C6orf62
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C6orf62 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C6orf62 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C6orf62 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C6orf62 |
Orthologs
for C6orf62 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for C6orf62 gene from 5/14 species (see all 14) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
BC0055371 , 5 |
cDNA sequence BC0055371, 5 |
96.22(n)1
100(a)1 |
|
13 (10.68 cM)5
795551 NM_024473.31 NP_077793.11
248016575 |
chicken
(Gallus gallus) |
Aves |
C2H6orf621 |
chromosome 2 open reading frame, human C6orf62 |
92.43(n)
97.82(a) |
|
421005 XM_419091.2 XP_419091.1 |
lizard
(Anolis carolinensis) |
Reptilia |
C6orf626 |
-- |
96(a) |
1 ↔ 1 |
4(53937392-53941505) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.241692 |
Xenopus laevis transcribed sequence with strong similarity more |
83.58(n) |
|
BJ062873.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb59h042 |
wufb59h04 |
79.55(n) |
|
322400 CK142829.1 |
ENSEMBL Gene Tree for C6orf62 (if available)
TreeFam Gene Tree for C6orf62 (if available) |
Paralogs
for C6orf62 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C6orf62 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C6orf62 (24705089 - 24721064 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for C6orf62
1 CNV: 51864 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C6orf62 |
|
Disorders
/ Diseases
for C6orf62 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C6orf62 for disorders About GeneDecksing
1  disease for C6orf62: About MalaCardsneuroblastoma
Export disorders for C6orf62 gene to outside databases
|
Publications
for C6orf62 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C6orf62 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C6orf62) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (2001)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
- A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
- Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma. (PubMed id 12880961)2 Ohira M.... Nakagawara A. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
- Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. (PubMed id 11256614)1 Simpson J.C.... Wiemann S. (2000)
|
External Searches for C6orf62 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C6orf62 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C6orf62 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C6orf62 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C6orf62 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C6orf62 gene:
Search GeneIP for patents involving C6orf62
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C6orf62 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C6orf62 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C6orf62 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C6orf62 | | | OriGene Protein Over-expression Lysate for C6orf62 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C6orf62 | | OriGene 3'-UTR Clone for C6orf62 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf62 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf62 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C6orf62 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C6orf62 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C6orf62 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C6orf62 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C6orf62 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C6orf62 |
| |
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| |  |  |  |  | | | | |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C6orf62 |
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