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Aliases for C6orf52 Gene

Aliases for C6orf52 Gene

  • Chromosome 6 Open Reading Frame 52 2 3

External Ids for C6orf52 Gene

Previous GeneCards Identifiers for C6orf52 Gene

  • GC06M010734
  • GC06M010779
  • GC06M010547

Summaries for C6orf52 Gene

GeneCards Summary for C6orf52 Gene

C6orf52 (Chromosome 6 Open Reading Frame 52) is a Protein Coding gene. An important paralog of this gene is TRNAU1AP.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf52 Gene

Genomics for C6orf52 Gene

Regulatory Elements for C6orf52 Gene

Genomic Location for C6orf52 Gene

10,671,418 bp from pter
10,694,797 bp from pter
23,380 bases
Minus strand

Genomic View for C6orf52 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C6orf52 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C6orf52 Gene

Proteins for C6orf52 Gene

  • Protein details for C6orf52 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative uncharacterized protein C6orf52
    Protein Accession:
    Secondary Accessions:
    • Q5T4I7
    • Q96AS6

    Protein attributes for C6orf52 Gene

    152 amino acids
    Molecular mass:
    17383 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH16820.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI14001.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for C6orf52 Gene


neXtProt entry for C6orf52 Gene

Proteomics data for C6orf52 Gene at MOPED

Post-translational modifications for C6orf52 Gene

No Post-translational modifications

Other Protein References for C6orf52 Gene

No data available for DME Specific Peptides for C6orf52 Gene

Domains for C6orf52 Gene

Protein Domains for C6orf52 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C6orf52: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C6orf52 Gene

Function for C6orf52 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C6orf52 Gene

Localization for C6orf52 Gene

Subcellular locations from

Jensen Localization Image for C6orf52 Gene COMPARTMENTS Subcellular localization image for C6orf52 gene
Compartment Confidence
cytosol 2
extracellular 2
nucleus 2
cytoskeleton 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C6orf52 Gene

Pathways for C6orf52 Gene

SuperPathways for C6orf52 Gene

No Data Available

Interacting Proteins for C6orf52 Gene

Gene Ontology (GO) - Biological Process for C6orf52 Gene


No data available for Pathways by source for C6orf52 Gene

Transcripts for C6orf52 Gene

Unigene Clusters for C6orf52 Gene

Chromosome 6 open reading frame 52:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C6orf52 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6
SP1: -
SP2: - -

Relevant External Links for C6orf52 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C6orf52 Gene

mRNA expression in normal human tissues for C6orf52 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C6orf52 Gene

This gene is overexpressed in Testis (8.5).

SOURCE GeneReport for Unigene cluster for C6orf52 Gene Hs.61389

genes like me logo Genes that share expressions with C6orf52: view

No data available for Protein expression and mRNA Expression by UniProt/SwissProt for C6orf52 Gene

Orthologs for C6orf52 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for C6orf52 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C6H6orf52 35
  • 99.34 (n)
  • 98.68 (a)
C6orf52 36
  • 99 (a)
(Canis familiaris)
Mammalia C35H6orf52 35
  • 79.2 (n)
  • 64.8 (a)
C6orf52 36
  • 63 (a)
(Monodelphis domestica)
Mammalia C6orf52 36
  • 30 (a)
(Ornithorhynchus anatinus)
Mammalia C6orf52 36
  • 27 (a)
(Rattus norvegicus)
Mammalia RGD1562963 35
  • 69.27 (n)
  • 52.34 (a)
(Gallus gallus)
Aves -- 36
  • 15 (a)
(Anolis carolinensis)
Reptilia C6orf52 36
  • 13 (a)
(Danio rerio)
Actinopterygii C19H6orf52 36
  • 11 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG15440 36
  • 3 (a)
(Caenorhabditis elegans)
Secernentea T07F10.3 36
  • 1 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes NAM8 36
  • 2 (a)
NGR1 36
  • 3 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 2 (a)
Species with no ortholog for C6orf52:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for C6orf52 Gene

Gene Tree for C6orf52 (if available)
Gene Tree for C6orf52 (if available)

Paralogs for C6orf52 Gene

Paralogs for C6orf52 Gene

genes like me logo Genes that share paralogs with C6orf52: view

Variants for C6orf52 Gene

Sequence variations from dbSNP and Humsavar for C6orf52 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs3737278 -- 10,671,531(+) GAGTC(A/G)TAGAG reference, synonymous-codon, nc-transcript-variant
rs4712827 -- 10,685,828(+) GAACA(C/T)CCACC intron-variant
rs6919114 -- 10,672,364(+) TATGC(C/T)tatta intron-variant
rs6925668 -- 10,689,838(+) ctaga(C/G)tggcc intron-variant
rs6935649 -- 10,672,418(+) aaccc(A/C)cacaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C6orf52 Gene

Variant ID Type Subtype PubMed ID
nsv462631 CNV Gain 19166990
nsv470800 CNV Gain 18288195
nsv520853 CNV Loss 19592680

Relevant External Links for C6orf52 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf52 Gene

Disorders for C6orf52 Gene

No disorders were found for C6orf52 Gene.

No data available for UniProtKB/Swiss-Prot for C6orf52 Gene

Publications for C6orf52 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for C6orf52 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate C6orf52
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for C6orf52
    • Block miRNA regulation of C6orf52 using miScript Target Protectors

    Sources for C6orf52 Gene

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