Aliases for C6orf47 Gene
Aliases for C6orf47 Gene
External Ids for C6orf47 Gene
- HGNC: 19076
- Entrez Gene: 57827
- Ensembl: ENSG00000204439
- UniProtKB: O95873
Previous GeneCards Identifiers for C6orf47 Gene
- GC06M031689
- GC06M031396
- GC06M031730
- GC06M031735
- GC06M031627
- GC06M031630
- GC06M031634
- GC06M031637
- GC06M031641
- GC06M031646
- GC06M031650
- GC06M031685
- GC06M031663
- GC06M031674
- GC06M031723
- GC06M031792
- GC06M031815
Summaries for C6orf47 Gene
GeneCards Summary for C6orf47 Gene
C6orf47 (Chromosome 6 Open Reading Frame 47) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf47 Gene
Genomics for C6orf47 Gene
Regulatory Elements for C6orf47 Gene
Enhancers for C6orf47 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around C6orf47 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the C6orf47 gene promoter:
Regulatory Element Products
Genomic Location for C6orf47 Gene
- Chromosome:
- 6
- Start:
- 31,658,298 bp from pter
- End:
- 31,660,772 bp from pter
- Size:
- 2,475 bases
- Orientation:
- Minus strand
Genomic View for C6orf47 Gene
Genes around C6orf47 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p21.33 by Ensembl
- 6p21.33 by Entrez Gene
- 6p21.33 by HGNC
C6orf47 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C6orf47 Gene
Proteins for C6orf47 Gene
-
Protein details for C6orf47 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95873-CF047_HUMAN
- Recommended name:
- Uncharacterized protein C6orf47
- Protein Accession:
- O95873
- B0UXA1
- B0UZ50
- Q5SSS6
- Q95IG0
Protein attributes for C6orf47 Gene
- Size:
- 294 amino acids
- Molecular mass:
- 31710 Da
- Quaternary structure:
- No Data Available
Protein Expression for C6orf47 Gene
Post-translational modifications for C6orf47 Gene
Other Protein References for C6orf47 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for C6orf47
- Invitrogen Antibodies for C6orf47
- Search GeneTex for Antibodies for C6orf47
Protein Products
-
OriGene Purified Proteins for C6orf47
- Search Origene for MassSpec and Protein Over-expression Lysates for C6orf47
- Origene Custom Protein Services for C6orf47
- Novus Biologicals proteins for C6orf47
- Search GeneTex for Proteins for C6orf47
Assay Products
No data available for DME Specific Peptides for C6orf47 Gene
Domains & Families for C6orf47 Gene
Suggested Antigen Peptide Sequences for C6orf47 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families and UniProtKB/Swiss-Prot for C6orf47 Gene
Function for C6orf47 Gene
Phenotypes for C6orf47 Gene
- GenomeRNAi human phenotypes for C6orf47:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for C6orf47 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for C6orf47 gene
- Search ViGene Biosciences for C6orf47
CRISPR Products
-
OriGene CRISPR knockouts for C6orf47
-
Santa Cruz Biotechnology (SCBT) CRISPR for C6orf47
- GenScript: Design CRISPR guide RNA sequences for C6orf47
miRNA for C6orf47 Gene
- miRTarBase miRNAs that target C6orf47
-
- hsa-mir-26a-5p (MIRT050157)
- hsa-mir-328-3p (MIRT528166)
- hsa-mir-192-3p (MIRT528167)
- hsa-mir-6851-3p (MIRT528168)
- hsa-mir-6775-3p (MIRT528169)
- hsa-mir-1291 (MIRT528170)
- hsa-mir-4290 (MIRT528171)
- hsa-mir-1976 (MIRT528172)
- hsa-mir-6747-3p (MIRT528173)
- hsa-mir-6727-3p (MIRT528174)
- hsa-mir-4722-3p (MIRT528175)
- hsa-mir-660-3p (MIRT528176)
- hsa-mir-4667-3p (MIRT528177)
- hsa-mir-323b-3p (MIRT528178)
- hsa-mir-193b-3p (MIRT528179)
- hsa-mir-193a-3p (MIRT528180)
- hsa-mir-429 (MIRT528181)
- hsa-mir-200c-3p (MIRT528182)
- hsa-mir-200b-3p (MIRT528183)
miRNA Products
- Search ViGene Biosciences for C6orf47
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C6orf47
- Browse OriGene Inhibitory RNA Products For C6orf47
-
ViGene Biosciences ready-to-package AAV shRNAs for C6orf47 gene
Clone Products
-
OriGene ORF clones in human for C6orf47
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C6orf47
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C6orf47
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for C6orf47
-
ViGene Biosciences adenoviral particle packaged cDNA for C6orf47 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for C6orf47 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for C6orf47 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C6orf47 Gene
Localization for C6orf47 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| plasma membrane | 3 |
| mitochondrion | 2 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | IDA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for C6orf47 Gene
Pathways & Interactions for C6orf47 Gene
No Data Available
Interacting Proteins for C6orf47 Gene
No data available for Pathways by source and SIGNOR curated interactions for C6orf47 Gene
Transcripts for C6orf47 Gene
mRNA/cDNA for C6orf47 Gene
- (1) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (94) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for C6orf47 Gene
CRISPR Products
-
OriGene CRISPR knockouts for C6orf47
-
Santa Cruz Biotechnology (SCBT) CRISPR for C6orf47
- GenScript: Design CRISPR guide RNA sequences for C6orf47
miRNA Products
- Search ViGene Biosciences for C6orf47
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C6orf47
- Browse OriGene Inhibitory RNA Products For C6orf47
-
ViGene Biosciences ready-to-package AAV shRNAs for C6orf47 gene
Clone Products
-
OriGene ORF clones in human for C6orf47
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C6orf47
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C6orf47
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for C6orf47 Gene
This gene is overexpressed in Colon (18.7), Urinary Bladder (17.4), Ovary (9.2), and Pancreas (7.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C6orf47 Gene
NURSA nuclear receptor signaling pathways regulating expression of C6orf47 Gene:
C6orf47SOURCE GeneReport for Unigene cluster for C6orf47 Gene:
Hs.247323Evidence on tissue expression from TISSUES for C6orf47 Gene
- Eye(4.1)
Primer Products
-
OriGene qPCR primer pairs and template standards for C6orf47
-
OriGene qPCR primer pairs for C6orf47
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C6orf47 Gene
Orthologs for C6orf47 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C6H6orf47 34 |
|
||
| dog (Canis familiaris) |
Mammalia | C12H6orf47 34 |
|
||
| cow (Bos Taurus) |
Mammalia | C23H6orf47 34 |
|
||
| C23H6ORF47 35 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | D17H6S53E 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | G4 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | C6orf47 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | C19H6orf47 35 |
|
OneToOne |
- Species where no ortholog for C6orf47 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for C6orf47 Gene
No data available for Paralogs for C6orf47 Gene
Variants for C6orf47 Gene
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1002270126 | -- | 31,660,913(+) | ATAAA(C/G)CCAGC | downstream-variant-500B, upstream-variant-2KB | |
| rs1003246539 | -- | 31,660,261(+) | CCAGA(C/G)AGTCC | intron-variant, utr-variant-5-prime | |
| rs1003859566 | -- | 31,657,993(+) | CCACC(C/T)CATTA | intron-variant, downstream-variant-500B | |
| rs1005016874 | -- | 31,661,876(+) | TTGCA(C/T)GAAGC | downstream-variant-500B, upstream-variant-2KB, utr-variant-3-prime | |
| rs1005477810 | -- | 31,658,629(+) | AGATC(C/T)TGAGA | intron-variant, downstream-variant-500B, utr-variant-3-prime |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv10403n54 | CNV | loss | 21841781 |
| dgv10404n54 | CNV | loss | 21841781 |
| nsv1073969 | CNV | deletion | 25765185 |
| nsv1112900 | CNV | deletion | 24896259 |
| nsv1126749 | CNV | deletion | 24896259 |
| nsv1161370 | CNV | deletion | 26073780 |
| nsv462871 | CNV | loss | 19166990 |
| nsv601942 | CNV | loss | 21841781 |
| nsv830627 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
78.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.32;
76.65% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for C6orf47 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C6orf47
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf47 Gene
Disorders for C6orf47 Gene
Relevant External Links for C6orf47
No disorders were found for C6orf47 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C6orf47 Gene
Publications for C6orf47 Gene
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4 64
- Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. (PMID: 14656967) Xie T. … Hood L. (Genome Res. 2003) 3 4 64
- Identification of multiple HTF-island associated genes in the human major histocompatibility complex class III region. (PMID: 2477242) Sargent C.A. … Campbell R.D. (EMBO J. 1989) 2 3 64
- Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 64
Products for C6orf47 Gene
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- Browse R&D Systems for biochemical assays
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- OriGene qPCR primer pairs and template standards for C6orf47
- OriGene qPCR primer pairs for C6orf47
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- Novus Biologicals Antibodies for C6orf47
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- ViGene Biosciences adenoviral particle packaged cDNA for C6orf47 gene
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- Horizon Cell Lines for C6orf47
- Cyagen custom Knockout/knockin (KOKI) mouse models for C6orf47
- VectorBuilder custom plasmid, inducible vectors for C6orf47
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C6orf47
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for C6orf47 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer