C6orf47 Gene
protein-coding GIFtS: 41
GCID: GC06M031646
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chromosome 6 open reading frame 47
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Aliases
for C6orf47 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 6 Open Reading Frame 471 2 | | G41 2 3 | | D6S53E1 2 | | Protein G42 3 | | NG342 | | Uncharacterized Protein C6orf472 |
Export aliases for C6orf47 gene to outside databasesPrevious GC identifers: GC06M031689 GC06M031396 GC06M031730 GC06M031735 GC06M031627 GC06M031630 GC06M031634 GC06M031637 GC06M031641 |
Summaries
for C6orf47 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C6orf47 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15 NT_113891.2 NT_167245.1 NT_167246.1 NT_167247.1 NT_167248.1
- NT_167249.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C6orf47 gene promoter:
PPAR-gamma1 Pax-5 HTF Hand1 HNF-4alpha2 PPAR-gamma2 E47 HNF-4alpha1
Other transcription factors
Search SABiosciences Chromatin IP Primers for C6orf47
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C6orf47 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p21.3 Ensembl cytogenetic band: 6p21.33 HGNC cytogenetic band: 6p21.3C6orf47 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M031646: view genomic region
(about GC identifiers)
Start:
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31,626,075 bp from pter |
End:
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31,628,549 bp from pter |
Size:
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2,475 bases |
Orientation:
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minus strand |
6 alternative locations:
| Chr6-,ALT_REF_LOCI_3 31,608,257-31,621,769 | Chr6-,ALT_REF_LOCI_4 31,588,623-31,591,098 | Chr6-,ALT_REF_LOCI_2 31,613,489-31,655,152 | | Chr6-,ALT_REF_LOCI_5 31,617,178-31,619,652 | Chr6-,ALT_REF_LOCI_6 31,616,315-31,654,370 | Chr6-,ALT_REF_LOCI_7 31,546,338-31,548,812 | |
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Proteins
for C6orf47 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CF047_HUMAN, O95873 (See
protein sequence)Recommended Name: Uncharacterized protein C6orf47 Size: 294 amino acids; 31710 Da
Secondary accessions: B0UXA1 B0UZ50 Q5SSS6 Q95IG0Explore the universe of human proteins at neXtProt for C6orf47: NX_O95873
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O95873
C6orf47 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_067007.3
ENSEMBL proteins: ENSP00000365076
Human Recombinant Protein Products:
C6orf47 Antibody Products:
Assay Products for C6orf47: |
Protein
Domains /
Families
for C6orf47 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: O95873 |
Function
for C6orf47 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf47 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf47
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C6orf47 (NM_021184) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C6orf47 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C6orf47 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C6orf47 |
1 GenomeRNAi human phenotype for C6orf47:
|
Pathways & Interactions
for C6orf47 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C6orf47
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
3 Interacting proteins for C6orf47 (O958733 ENSP000003650764) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for C6orf47 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C6orf47
Search CenterWatch for drugs/clinical trials and news about C6orf47 / CF047
|
Transcripts
for C6orf47 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C6orf47 gene: NM_021184.3 Unigene Cluster for C6orf47: Chromosome 6 open reading frame 47 Hs.247323 [show with all ESTs]Unigene Representative Sequence: NM_0211841 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000375911(uc003nvm.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf47 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf47
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C6orf47 (NM_021184) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C6orf47 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C6orf47 |
Additional cDNA sequence: AJ245433.1 AK315349.1 BC012950.1 BC063584.1 6 DOTS entries: DT.121312702 DT.452848 DT.91768636 DT.121312771 DT.91768626 DT.91700705 24/94 AceView cDNA sequences (see all 94): BE549642 AI272171 AI703075 BM808745 BM915324 BC012950 BC063584 BI820798 AV725733 AI278956 AA447094 AA236884 AA455884 BM550864 AL570738 AW189292 BQ446760 BI858749 BQ017906 BQ575043 BQ001892 BI457130 AA508848 AA351927
GeneLoc Exon Structure
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Expression
for C6orf47 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C6orf47 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGAGCCAGAG
About this image
See C6orf47 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C6orf47
SOURCE GeneReport for Unigene cluster: Hs.247323
SABiosciences Custom PCR Arrays for C6orf47
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C6orf47
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C6orf47 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C6orf47 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C6orf47 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C6orf47 |
Orthologs
for C6orf47 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for C6orf47 gene from 1/5 species (see all 5) About this table
ENSEMBL Gene Tree for C6orf47 (if available)
TreeFam Gene Tree for C6orf47 (if available) |
Paralogs
for C6orf47 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C6orf47 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C6orf47 (31626075 - 31628549 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C6orf47: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C6orf47 |
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Disorders
/ Diseases
for C6orf47 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C6orf47 for disorders About GeneDecksing
9  diseases for C6orf47: About MalaCardshuman t-cell leukemia virus type 1 systemic lupus erythematosus lupus erythematosus gastroenteritis
t-cell leukemia rheumatoid arthritis diarrhea arthritis
leukemia
Human Genome Epidemiology (HuGE) Navigator: C6orf47 (7 documents)
Export disorders for C6orf47 gene to outside databases
|
Publications
for C6orf47 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C6orf47 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with C6orf47) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. (PubMed id 14656967)1, 2 Xie T.... Hood L. (2003)
- Identification of multiple HTF-island associated genes in the human major histocompatibility complex class III region. (PubMed id 2477242)1, 3 Sargent C.A.... Campbell R.D. (1989)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
- Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
- High-density SNP screening of the major histocompatib ility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1 Barcellos L.F....Criswell L.A. (2009)
- Association of MHC SNP genotype with susceptibility to type 1 diabetes: a modified survival approach. (PubMed id 19143821)1 McKinnon E....James I. (2009)
- Fine mapping of the MHC Class III region demonstrates association of AIF1 and rheumatoid arthritis. (PubMed id 18835879)1 Harney S.M....Brown M.A. (2008)
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External Searches for C6orf47 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing C6orf47 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C6orf47 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C6orf47 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C6orf47 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for C6orf47 gene:
Search GeneIP for patents involving C6orf47
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C6orf47 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C6orf47 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C6orf47 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C6orf47 | | | OriGene Protein Over-expression Lysate for C6orf47 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C6orf47 | | OriGene 3'-UTR Clone for C6orf47 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf47 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf47 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C6orf47 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C6orf47 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C6orf47 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C6orf47 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C6orf47 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C6orf47 |
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| | | | Search Tocris compounds for C6orf47 |
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 | | | C6orf47 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C6orf47 |
|  |  |  | | | | Search ThermoFisher Antibodies for C6orf47 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C6orf47 |
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