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Aliases for C6orf47 Gene

Aliases for C6orf47 Gene

  • Chromosome 6 Open Reading Frame 47 2 3 5
  • Protein G4 3 4
  • G4 3 4
  • D6S53E 3
  • NG34 3

External Ids for C6orf47 Gene

Previous GeneCards Identifiers for C6orf47 Gene

  • GC06M031689
  • GC06M031396
  • GC06M031730
  • GC06M031735
  • GC06M031627
  • GC06M031630
  • GC06M031634
  • GC06M031637
  • GC06M031641
  • GC06M031646
  • GC06M031650
  • GC06M031685
  • GC06M031663
  • GC06M031674

Summaries for C6orf47 Gene

GeneCards Summary for C6orf47 Gene

C6orf47 (Chromosome 6 Open Reading Frame 47) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf47 Gene

Genomics for C6orf47 Gene

Regulatory Elements for C6orf47 Gene

Promoters for C6orf47 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C6orf47 on UCSC Golden Path with GeneCards custom track

Genomic Location for C6orf47 Gene

Chromosome:
6
Start:
31,658,298 bp from pter
End:
31,660,772 bp from pter
Size:
2,475 bases
Orientation:
Minus strand

Genomic View for C6orf47 Gene

Genes around C6orf47 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C6orf47 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C6orf47 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for C6orf47 Gene

  • Protein details for C6orf47 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O95873-CF047_HUMAN
    Recommended name:
    Uncharacterized protein C6orf47
    Protein Accession:
    O95873
    Secondary Accessions:
    • B0UXA1
    • B0UZ50
    • Q5SSS6
    • Q95IG0

    Protein attributes for C6orf47 Gene

    Size:
    294 amino acids
    Molecular mass:
    31710 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C6orf47 Gene

Proteomics data for C6orf47 Gene at MOPED

Post-translational modifications for C6orf47 Gene

  • Ubiquitination at Lys 147 and Lys 153
  • Modification sites at PhosphoSitePlus

Other Protein References for C6orf47 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C6orf47 Gene

Domains & Families for C6orf47 Gene

Protein Domains for C6orf47 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C6orf47 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C6orf47: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C6orf47 Gene

Function for C6orf47 Gene

Phenotypes for C6orf47 Gene

GenomeRNAi human phenotypes for C6orf47:
genes like me logo Genes that share phenotypes with C6orf47: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C6orf47 Gene

Localization for C6orf47 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C6orf47 Gene COMPARTMENTS Subcellular localization image for C6orf47 gene
Compartment Confidence
plasma membrane 3
mitochondrion 2
cytosol 1
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C6orf47 Gene

Pathways & Interactions for C6orf47 Gene

SuperPathways for C6orf47 Gene

No Data Available

Interacting Proteins for C6orf47 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000365076%0d%0a9606.ENSP00000339824%0d%0a
Selected Interacting proteins: O95873-CF047_HUMAN ENSP00000365076 for C6orf47 Gene via I2D STRING

Gene Ontology (GO) - Biological Process for C6orf47 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C6orf47 Gene

Drugs & Compounds for C6orf47 Gene

No Compound Related Data Available

Transcripts for C6orf47 Gene

mRNA/cDNA for C6orf47 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(94) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C6orf47 Gene

Chromosome 6 open reading frame 47:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C6orf47 Gene

No ASD Table

Relevant External Links for C6orf47 Gene

GeneLoc Exon Structure for
C6orf47
ECgene alternative splicing isoforms for
C6orf47

Expression for C6orf47 Gene

mRNA expression in normal human tissues for C6orf47 Gene

Protein differential expression in normal tissues from HIPED for C6orf47 Gene

This gene is overexpressed in Colon (18.7), Urinary Bladder (17.4), Ovary (9.2), and Pancreas (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C6orf47 Gene



SOURCE GeneReport for Unigene cluster for C6orf47 Gene Hs.247323

genes like me logo Genes that share expression patterns with C6orf47: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C6orf47 Gene

Orthologs for C6orf47 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C6orf47 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C6H6orf47 35
  • 99.21 (n)
  • 98.3 (a)
cow
(Bos Taurus)
Mammalia C23H6orf47 35
  • 83.5 (n)
  • 81.57 (a)
C23H6ORF47 36
  • 80 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C12H6orf47 35
  • 85.05 (n)
  • 81.1 (a)
mouse
(Mus musculus)
Mammalia D17H6S53E 35
  • 79.29 (n)
  • 76.11 (a)
D17H6S53E 16
D17H6S53E 36
  • 76 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C6orf47 36
  • 53 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia G4 35
  • 78.84 (n)
  • 75.43 (a)
zebrafish
(Danio rerio)
Actinopterygii C19H6orf47 36
  • 23 (a)
OneToOne
Species with no ortholog for C6orf47:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C6orf47 Gene

ENSEMBL:
Gene Tree for C6orf47 (if available)
TreeFam:
Gene Tree for C6orf47 (if available)

Paralogs for C6orf47 Gene

No data available for Paralogs for C6orf47 Gene

Variants for C6orf47 Gene

Sequence variations from dbSNP and Humsavar for C6orf47 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
VAR_022911 -
VAR_056797 -

Structural Variations from Database of Genomic Variants (DGV) for C6orf47 Gene

Variant ID Type Subtype PubMed ID
nsv830627 CNV Loss 17160897
nsv884418 CNV Gain 21882294
nsv462871 CNV Loss 19166990
dgv6581n71 CNV Loss 21882294

Variation tolerance for C6orf47 Gene

Residual Variation Intolerance Score: 78.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.32; 76.65% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C6orf47 Gene

HapMap Linkage Disequilibrium report
C6orf47

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf47 Gene

Disorders for C6orf47 Gene

Relevant External Links for C6orf47

Genetic Association Database (GAD)
C6orf47
Human Genome Epidemiology (HuGE) Navigator
C6orf47
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C6orf47

No disorders were found for C6orf47 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C6orf47 Gene

Publications for C6orf47 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Identification of multiple HTF-island associated genes in the human major histocompatibility complex class III region. (PMID: 2477242) Sargent C.A. … Campbell R.D. (EMBO J. 1989) 2 3
  3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3
  4. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PMID: 19851445) Barcellos L.F. … Criswell L.A. (PLoS Genet. 2009) 3
  5. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 3

Products for C6orf47 Gene

Sources for C6orf47 Gene

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