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Aliases for C6orf223 Gene

Aliases for C6orf223 Gene

  • Chromosome 6 Open Reading Frame 223 2 3

External Ids for C6orf223 Gene

Previous GeneCards Identifiers for C6orf223 Gene

  • GC06P044077
  • GC06P043690

Summaries for C6orf223 Gene

GeneCards Summary for C6orf223 Gene

C6orf223 (Chromosome 6 Open Reading Frame 223) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf223 Gene

Genomics for C6orf223 Gene

Regulatory Elements for C6orf223 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C6orf223 Gene

44,000,580 bp from pter
44,005,958 bp from pter
5,379 bases
Plus strand

Genomic View for C6orf223 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C6orf223 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C6orf223 Gene

Proteins for C6orf223 Gene

  • Protein details for C6orf223 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C6orf223
    Protein Accession:
    Secondary Accessions:
    • E9PB59
    • Q8N575

    Protein attributes for C6orf223 Gene

    242 amino acids
    Molecular mass:
    26113 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH32706.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305};

    Alternative splice isoforms for C6orf223 Gene


neXtProt entry for C6orf223 Gene

Proteomics data for C6orf223 Gene at MOPED

Post-translational modifications for C6orf223 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C6orf223 Gene

Antibody Products

No data available for DME Specific Peptides for C6orf223 Gene

Domains for C6orf223 Gene

Protein Domains for C6orf223 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C6orf223: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C6orf223 Gene

Function for C6orf223 Gene

Phenotypes for C6orf223 Gene

GenomeRNAi human phenotypes for C6orf223:
genes like me logo Genes that share phenotypes with C6orf223: view

Animal Model Products

CRISPR Products

miRNA for C6orf223 Gene

miRTarBase miRNAs that target C6orf223

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for C6orf223 Gene

Localization for C6orf223 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C6orf223 Gene

Pathways for C6orf223 Gene

SuperPathways for C6orf223 Gene

No Data Available

Interacting Proteins for C6orf223 Gene

Gene Ontology (GO) - Biological Process for C6orf223 Gene


No data available for Pathways by source for C6orf223 Gene

Transcripts for C6orf223 Gene

mRNA/cDNA for C6orf223 Gene

Unigene Clusters for C6orf223 Gene

Chromosome 6 open reading frame 223:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C6orf223 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4
SP1: - -
SP2: -
SP3: - - -

Relevant External Links for C6orf223 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C6orf223 Gene

mRNA expression in normal human tissues for C6orf223 Gene

mRNA differential expression in normal tissues according to GTEx for C6orf223 Gene

This gene is overexpressed in Lung (8.1) and Kidney - Cortex (4.6).

Protein differential expression in normal tissues for C6orf223 Gene

This gene is overexpressed in Neutrophil (45.8) and Pancreas (21.7).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C6orf223 Gene

SOURCE GeneReport for Unigene cluster for C6orf223 Gene Hs.531926

genes like me logo Genes that share expressions with C6orf223: view

Expression partners for C6orf223 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C6orf223 Gene

Orthologs for C6orf223 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C6orf223 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C23H6orf223 35
  • 72.27 (n)
  • 61.06 (a)
(Pan troglodytes)
Mammalia C6H6orf223 35
  • 99.86 (n)
  • 99.58 (a)
C6orf223 36
  • 100 (a)
Species with no ortholog for C6orf223:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C6orf223 Gene

Gene Tree for C6orf223 (if available)
Gene Tree for C6orf223 (if available)

Paralogs for C6orf223 Gene

No data available for Paralogs for C6orf223 Gene

Variants for C6orf223 Gene

Sequence variations from dbSNP and Humsavar for C6orf223 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs2273306 -- 44,004,888(+) TCCCC(C/G)CTTCA utr-variant-3-prime
rs2273307 -- 44,004,992(+) GCTGT(C/G)TCCCC utr-variant-3-prime
rs2273308 -- 44,004,996(+) TCTCC(C/T)CCTCC utr-variant-3-prime
rs2273309 -- 44,005,108(+) ACACC(A/G)TTTGT utr-variant-3-prime
rs2273310 -- 44,005,345(+) CAGAC(C/T)CTGAG utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for C6orf223 Gene

Variant ID Type Subtype PubMed ID
nsv509131 CNV Insertion 20534489
nsv462934 CNV Loss 19166990
esv2732001 CNV Deletion 23290073
esv2732002 CNV Deletion 23290073

Relevant External Links for C6orf223 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf223 Gene

Disorders for C6orf223 Gene

No disorders were found for C6orf223 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for C6orf223 Gene

Publications for C6orf223 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels. (PMID: 21757650) Debette S. … Seshadri S. (Circ. Res. 2011) 3

Products for C6orf223 Gene

Sources for C6orf223 Gene

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