C6orf203 Gene
protein-coding GIFtS: 43
GCID: GC06P107394
|
|
chromosome 6 open reading frame 203
| |
Aliases
for C6orf203 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 6 Open Reading Frame 2031 2 | | HSPC2301 2 | | PRED311 2 | | RP11-59I9.12 | | Uncharacterized Protein C6orf2032 |
Export aliases for C6orf203 gene to outside databasesPrevious GC identifers: GC06P107349 GC06P107456 GC06P104921 |
Summaries
for C6orf203 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C6orf203 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_025741.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C6orf203 gene promoter:
AREB6 Sp1 NRF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for C6orf203
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C6orf203 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6q21 Ensembl cytogenetic band: 6q21 HGNC cytogenetic band: 6q21C6orf203 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P107394: view genomic region
(about GC identifiers)
Start:
|
107,349,407 bp from pter |
End:
|
107,372,546 bp from pter |
Size:
|
23,140 bases |
Orientation:
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plus strand |
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Proteins
for C6orf203 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CF203_HUMAN, Q9P0P8 (See
protein sequence)Recommended Name: Uncharacterized protein C6orf203 Size: 240 amino acids; 27941 Da
Secondary accessions: B3KRG9Explore the universe of human proteins at neXtProt for C6orf203: NX_Q9P0P8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9P0P8
C6orf203 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001135940.1 NP_001135942.1 NP_057571.1
ENSEMBL proteins: ENSP00000310951 ENSP00000390153 ENSP00000384867
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005739 | mitochondrion |
-- | -- |
C6orf203 for ontologies About GeneDecksing
C6orf203 Antibody Products:
Assay Products for C6orf203: |
Protein
Domains /
Families
for C6orf203 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9P0P8 |
Function
for C6orf203 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf203 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf203 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C6orf203 |
|
Pathways & Interactions
for C6orf203 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C6orf203
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
5/232 Interacting proteins for C6orf203 (Q9P0P82, 3 ENSP000003109514) via UniProtKB, MINT, STRING, and/or I2D (see all 232)About this table
|
Drugs & Compounds
for C6orf203 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C6orf203
Search CenterWatch for drugs/clinical trials and news about C6orf203 / CF203
|
Transcripts
for C6orf203 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C6orf203 gene (3 alternative transcripts): NM_001142468.1 NM_001142470.1 NM_016487.3 Unigene Cluster for C6orf203: Chromosome 6 open reading frame 203 Hs.486084 [show with all ESTs]Unigene Representative Sequence: NM_0011424704 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000311381 ENST00000489790 ENST00000443043(uc011eaj.2) ENST00000405204(uc003prq.3 uc010kde.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf203 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf203 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): C6orf203 (NM_016487) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C6orf203 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C6orf203 |
Additional cDNA sequence: AF151064.1 AK091564.1 BC010899.2 5 DOTS entries: DT.442918 DT.92420231 DT.92420230 DT.95262861 DT.40192527 24/50 AceView cDNA sequences (see all 50): CD673919 BQ671828 AI082607 AK091564 AI654973 CD511858 AI672676 BX333652 AA724440 AI796739 CR622886 AI087339 AW295065 AW051309 AA973689 AF151064 AI378492 BC010899 BX101012 AA345172 AA905266 BG623230 AI762443 BQ212846
GeneLoc Exon Structure
|
Expression
for C6orf203 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C6orf203 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGAGATGAG
About this image
See C6orf203 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C6orf203
SOURCE GeneReport for Unigene cluster: Hs.486084
SABiosciences Custom PCR Arrays for C6orf203
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C6orf203
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C6orf203 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C6orf203 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C6orf203 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C6orf203 |
Orthologs
for C6orf203 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for C6orf203 gene from 6/14 species (see all 14) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
1700021F05Rik1 , 5 |
RIKEN cDNA 1700021F05 gene1, 5 |
80.61(n)1
79.5(a)1 |
|
10 (23.01 cM)5
678511 NM_026411.11 NP_080687.11
435251335 |
chicken
(Gallus gallus) |
Aves |
C3H6orf2031 |
chromosome 3 open reading frame, human C6orf203 |
64.01(n)
56.19(a) |
|
421779 XM_419806.2 XP_419806.1 |
lizard
(Anolis carolinensis) |
Reptilia |
C6orf2036 |
-- |
50(a) |
1 ↔ 1 |
1(189624579-189628195) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.192282 |
Xenopus laevis transcribed sequence with weak similarity more |
70.62(n) |
|
BJ637748.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
si:ch211-206k20.56 |
si:ch211-206k20.5 |
39(a) |
1 ↔ 1 |
13(32859799-32865139) |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG48846 |
-- |
29(a) |
1 ↔ 1 |
3R(23783106-23784307) |
ENSEMBL Gene Tree for C6orf203 (if available)
TreeFam Gene Tree for C6orf203 (if available) |
Paralogs
for C6orf203 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for C6orf203 gene
C6orf203 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for C6orf203
PGOHUM00000259673 PGOHUM00000260192
|
Genomic Variants
for C6orf203 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C6orf203 (107349407 - 107372546 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for C6orf203
1 CNV: 4504 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C6orf203 |
|
Disorders
/ Diseases
for C6orf203 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C6orf203 for disorders About GeneDecksing
1  disease for C6orf203: About MalaCardsdown syndrome
Human Genome Epidemiology (HuGE) Navigator: C6orf203 (2 documents)
Export disorders for C6orf203 gene to outside databases
|
Publications
for C6orf203 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C6orf203 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with C6orf203) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (2000)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map. (PubMed id 11707072)1, 3 Reymond A....Antonarakis S.E. (2001)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome. (PubMed id 20186120)1 Richter R....Chrzanowska-Lightowlers Z.M. (2010)
- Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
|
External Searches for C6orf203 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C6orf203 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C6orf203 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C6orf203 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C6orf203 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C6orf203 gene:
Search GeneIP for patents involving C6orf203
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C6orf203 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C6orf203 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C6orf203 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C6orf203 | | | OriGene Protein Over-expression Lysate for C6orf203 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C6orf203 | | OriGene 3'-UTR Clone for C6orf203 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf203 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C6orf203 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 | | | C6orf203 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C6orf203 |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C6orf203 |
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