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Aliases for C6orf203 Gene

Aliases for C6orf203 Gene

  • Chromosome 6 Open Reading Frame 203 2 3 5
  • Uncharacterized Protein C6orf203 3
  • HSPC230 3
  • PRED31 3

External Ids for C6orf203 Gene

Previous GeneCards Identifiers for C6orf203 Gene

  • GC06P107349
  • GC06P107394
  • GC06P107456
  • GC06P104921

Summaries for C6orf203 Gene

GeneCards Summary for C6orf203 Gene

C6orf203 (Chromosome 6 Open Reading Frame 203) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf203 Gene

Genomics for C6orf203 Gene

Regulatory Elements for C6orf203 Gene

Enhancers for C6orf203 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F106997 1 Ensembl ENCODE 12 -30.1 -30054 1.9 CTCF ZNF792 SAP130 ZNF48 ZNF644 ZNF2 RAD21 CHAMP1 FOXK2 ZNF143 C6orf203 QRSL1 RTN4IP1 CD24
GH06F107060 0.8 Ensembl ENCODE 12.1 +33.4 33354 1.4 SOX13 ZNF316 IKZF1 MAFK C6orf203 PIR49317
GH06F107027 1.1 ENCODE 8.7 +0.2 194 1.6 PKNOX1 ARNT CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 CBX5 ZNF207 BEND3 C6orf203 RPL3P7 PIR49317
GH06F107064 1 Ensembl ENCODE 0.3 +36.9 36929 1.4 SCRT1 IRF2 NFIA NR2F1 ETV1 ASH2L ELF1 GABPA NR2F2 TFDP1 PIR49317 C6orf203
GH06F107021 0.6 ENCODE 0.4 -6.2 -6241 0.2 JUND JUN CUX1 FOS SP7 C6orf203 CD24
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C6orf203 on UCSC Golden Path with GeneCards custom track

Promoters for C6orf203 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001223680 429 1600 PKNOX1 ARNT CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 CBX5 ZNF207

Transcription factor binding sites by QIAGEN in the C6orf203 gene promoter:

Genomic Location for C6orf203 Gene

Chromosome:
6
Start:
107,028,172 bp from pter
End:
107,051,586 bp from pter
Size:
23,415 bases
Orientation:
Plus strand

Genomic View for C6orf203 Gene

Genes around C6orf203 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C6orf203 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C6orf203 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C6orf203 Gene

Proteins for C6orf203 Gene

  • Protein details for C6orf203 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9P0P8-CF203_HUMAN
    Recommended name:
    Uncharacterized protein C6orf203
    Protein Accession:
    Q9P0P8
    Secondary Accessions:
    • B3KRG9

    Protein attributes for C6orf203 Gene

    Size:
    240 amino acids
    Molecular mass:
    27941 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C6orf203 Gene

Post-translational modifications for C6orf203 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C6orf203 Gene

Domains & Families for C6orf203 Gene

Protein Domains for C6orf203 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C6orf203: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C6orf203 Gene

Function for C6orf203 Gene

Phenotypes for C6orf203 Gene

genes like me logo Genes that share phenotypes with C6orf203: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C6orf203 Gene

Localization for C6orf203 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C6orf203 gene
Compartment Confidence
mitochondrion 5
extracellular 2
peroxisome 1
nucleus 1
endoplasmic reticulum 1
cytosol 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for C6orf203 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IDA 20833797
genes like me logo Genes that share ontologies with C6orf203: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C6orf203 Gene

Pathways & Interactions for C6orf203 Gene

SuperPathways for C6orf203 Gene

No Data Available

Interacting Proteins for C6orf203 Gene

Selected Interacting proteins: Q9P0P8-CF203_HUMAN for C6orf203 Gene via MINT IID

Gene Ontology (GO) - Biological Process for C6orf203 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C6orf203 Gene

Transcripts for C6orf203 Gene

Unigene Clusters for C6orf203 Gene

Chromosome 6 open reading frame 203:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C6orf203 Gene

No ASD Table

Relevant External Links for C6orf203 Gene

GeneLoc Exon Structure for
C6orf203
ECgene alternative splicing isoforms for
C6orf203

Expression for C6orf203 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C6orf203 Gene

Protein differential expression in normal tissues from HIPED for C6orf203 Gene

This gene is overexpressed in Lung (7.6) and Peripheral blood mononuclear cells (7.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C6orf203 Gene



Protein tissue co-expression partners for C6orf203 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C6orf203 Gene:

C6orf203

SOURCE GeneReport for Unigene cluster for C6orf203 Gene:

Hs.486084
genes like me logo Genes that share expression patterns with C6orf203: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C6orf203 Gene

Orthologs for C6orf203 Gene

This gene was present in the common ancestor of animals.

Orthologs for C6orf203 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C6orf203 35
  • 100 (a)
OneToOne
C6H6orf203 34
  • 99.45 (n)
dog
(Canis familiaris)
Mammalia C12H6orf203 34
  • 86.19 (n)
C6orf203 35
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700021F05Rik 34 16 35
  • 80.61 (n)
rat
(Rattus norvegicus)
Mammalia LOC683897 34
  • 79.78 (n)
oppossum
(Monodelphis domestica)
Mammalia C6orf203 35
  • 69 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C9H6ORF203 35
  • 67 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C6orf203 35
  • 53 (a)
OneToOne
chicken
(Gallus gallus)
Aves C3H6ORF203 34 35
  • 66.22 (n)
lizard
(Anolis carolinensis)
Reptilia C6orf203 35
  • 51 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c6orf203 34
  • 56.48 (n)
Str.16694 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.19228 34
zebrafish
(Danio rerio)
Actinopterygii C13H6orf203 35
  • 40 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG4884 35
  • 30 (a)
OneToOne
Species where no ortholog for C6orf203 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C6orf203 Gene

ENSEMBL:
Gene Tree for C6orf203 (if available)
TreeFam:
Gene Tree for C6orf203 (if available)

Paralogs for C6orf203 Gene

Pseudogenes.org Pseudogenes for C6orf203 Gene

genes like me logo Genes that share paralogs with C6orf203: view

No data available for Paralogs for C6orf203 Gene

Variants for C6orf203 Gene

Sequence variations from dbSNP and Humsavar for C6orf203 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs10531599 -- 107,043,600(+) ATAAG(-/GAAG)TGAAA intron-variant
rs10599769 -- 107,048,779(+) ATGTC(-/A)AAAAA intron-variant
rs111504202 -- 107,028,072(+) GTGCC(C/T)CGAGC upstream-variant-2KB
rs111522204 -- 107,036,293(+) AATCT(C/G)AGCAC intron-variant
rs111555099 -- 107,033,081(+) TGGCT(A/G)TAGTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C6orf203 Gene

Variant ID Type Subtype PubMed ID
dgv6135n100 CNV gain 25217958
dgv87n68 CNV loss 17160897
esv2732546 CNV deletion 23290073
esv3610289 CNV loss 21293372
esv3610290 CNV loss 21293372
nsv508425 CNV deletion 20534489
nsv509145 CNV insertion 20534489
nsv510909 OTHER complex 20534489
nsv5431 CNV insertion 18451855

Variation tolerance for C6orf203 Gene

Residual Variation Intolerance Score: 73.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.15; 23.22% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C6orf203 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C6orf203

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf203 Gene

Disorders for C6orf203 Gene

Relevant External Links for C6orf203

Human Genome Epidemiology (HuGE) Navigator
C6orf203
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C6orf203

No disorders were found for C6orf203 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C6orf203 Gene

Publications for C6orf203 Gene

  1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang Q.-H. … Chen Z. (Genome Res. 2000) 2 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4 64
  5. From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map. (PMID: 11707072) Reymond A. … Antonarakis S.E. (Genomics 2001) 2 3 64

Products for C6orf203 Gene

Sources for C6orf203 Gene

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