Aliases for C6orf201 Gene
Aliases for C6orf201 Gene
External Ids for C6orf201 Gene
- HGNC: 21620
- Entrez Gene: 404220
- Ensembl: ENSG00000185689
- UniProtKB: Q7Z4U5
Previous GeneCards Identifiers for C6orf201 Gene
- GC00U914401
- GC06U900580
- GC06P004025
- GC06P003955
Summaries for C6orf201 Gene
GeneCards Summary for C6orf201 Gene
C6orf201 (Chromosome 6 Open Reading Frame 201) is a Protein Coding gene. Among its related pathways are Mesodermal Commitment Pathway.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf201 Gene
Genomics for C6orf201 Gene
Regulatory Elements for C6orf201 Gene
Enhancers for C6orf201 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH06G004133 | 1.1 | ENCODE | 27.4 | +56.0 | 56025 | 3.8 | HDGF CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF766 | C6orf201 FAM217A ECI2 ENSG00000254821 GC06P004132 |
| GH06G004188 | 0.6 | FANTOM5 | 40.2 | +109.8 | 109779 | 0.1 | SCRT1 CBX3 SCRT2 NRF1 ZBTB33 | C6orf201 FAM217A LOC100129052 LOC100507506 |
| GH06G004125 | 0.8 | ENCODE | 21.4 | +47.1 | 47124 | 2.1 | CTCF SAP130 JUN CEBPG RAD21 RARA TEAD3 FOSL1 SMC3 ZNF584 | C6orf201 ECI2 GC06P004125 GC06P004132 |
| GH06G004055 | 0.8 | ENCODE | 16.7 | -23.5 | -23498 | 1.3 | CTCF FOXA2 PKNOX1 JUN RAD21 TEAD3 FOSL1 SLC30A9 FOXK2 SMC3 | ENSG00000230648 C6orf201 FAM217A PRPF4B GC06M004041 GC06M004066 |
| GH06G004109 | 0.9 | ENCODE | 11.9 | +30.5 | 30476 | 0.2 | ELF3 INSM2 FEZF1 ZNF2 ZNF366 ZSCAN5C ZNF350 KLF7 ZNF391 ZNF362 | ENSG00000254821 LOC100507506 ECI2 FAM217A C6orf201 GC06P004125 GC06M004088 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around C6orf201 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the C6orf201 gene promoter:
Regulatory Element Products
Genomic Location for C6orf201 Gene
- Chromosome:
- 6
- Start:
- 4,079,206 bp from pter
- End:
- 4,130,951 bp from pter
- Size:
- 51,746 bases
- Orientation:
- Plus strand
Genomic View for C6orf201 Gene
Genes around C6orf201 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p25.2 by Ensembl
- 6p25.2 by Entrez Gene
- 6p25.2 by HGNC
C6orf201 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C6orf201 Gene
Proteins for C6orf201 Gene
-
Protein details for C6orf201 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q7Z4U5-CF201_HUMAN
- Recommended name:
- Uncharacterized protein C6orf201
- Protein Accession:
- Q7Z4U5
- A6NLI6
- Q6NXN5
Protein attributes for C6orf201 Gene
- Size:
- 140 amino acids
- Molecular mass:
- 16243 Da
- Quaternary structure:
- No Data Available
Protein Expression for C6orf201 Gene
Post-translational modifications for C6orf201 Gene
Other Protein References for C6orf201 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for C6orf201
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-
Abcam antibodies for C6orf201
- Invitrogen Antibodies for C6orf201
- GeneTex C6orf201 antibody for C6orf201
-
Santa Cruz Biotechnology (SCBT) Antibodies for C6orf201
Protein Products
-
OriGene Purified Proteins for C6orf201
- Search Origene for MassSpec and Protein Over-expression Lysates for C6orf201
- Origene Custom Protein Services for C6orf201
- Novus Biologicals lysates for C6orf201
- Search GeneTex for Proteins for C6orf201
Assay Products
No data available for DME Specific Peptides for C6orf201 Gene
Domains & Families for C6orf201 Gene
Suggested Antigen Peptide Sequences for C6orf201 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families and UniProtKB/Swiss-Prot for C6orf201 Gene
Function for C6orf201 Gene
Phenotypes for C6orf201 Gene
- GenomeRNAi human phenotypes for C6orf201:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for C6orf201
-
-
ViGene Biosciences lentiviral particle packaged cDNA for C6orf201 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for C6orf201 gene
- Search ViGene Biosciences for C6orf201
CRISPR Products
-
OriGene CRISPR knockouts for C6orf201
-
Santa Cruz Biotechnology (SCBT) CRISPR for C6orf201
- GenScript: Design CRISPR guide RNA sequences for C6orf201
miRNA for C6orf201 Gene
- miRTarBase miRNAs that target C6orf201
miRNA Products
- Search ViGene Biosciences for C6orf201
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C6orf201
- Browse OriGene Inhibitory RNA Products For C6orf201
-
ViGene Biosciences ready-to-package AAV shRNAs for C6orf201 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C6orf201
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C6orf201
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for C6orf201
-
ViGene Biosciences adenoviral particle packaged cDNA for C6orf201 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for C6orf201 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for C6orf201 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C6orf201 Gene
Localization for C6orf201 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 2 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C6orf201 Gene
Pathways & Interactions for C6orf201 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Mesodermal Commitment Pathway | ||
Pathways by source for C6orf201 Gene
1 BioSystems pathway for C6orf201 Gene
Interacting Proteins for C6orf201 Gene
No data available for SIGNOR curated interactions for C6orf201 Gene
Transcripts for C6orf201 Gene
mRNA/cDNA for C6orf201 Gene
- (5) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (33) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for C6orf201 Gene
CRISPR Products
-
OriGene CRISPR knockouts for C6orf201
-
Santa Cruz Biotechnology (SCBT) CRISPR for C6orf201
- GenScript: Design CRISPR guide RNA sequences for C6orf201
miRNA Products
- Search ViGene Biosciences for C6orf201
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C6orf201
- Browse OriGene Inhibitory RNA Products For C6orf201
-
ViGene Biosciences ready-to-package AAV shRNAs for C6orf201 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C6orf201
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C6orf201
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||
| SP2: | |||||||||||||||||||||
| SP3: | - | - | - | - | |||||||||||||||||
| SP4: | - | - |
Expression for C6orf201 Gene
mRNA differential expression in normal tissues according to GTEx for C6orf201 Gene
This gene is overexpressed in Testis (x43.5).
This gene is overexpressed in Pancreas (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C6orf201 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of C6orf201 Gene:
C6orf201SOURCE GeneReport for Unigene cluster for C6orf201 Gene:
Hs.716731Primer Products
-
OriGene qPCR primer pairs for C6orf201
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C6orf201 Gene
Orthologs for C6orf201 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C6H6orf201 34 |
|
||
| C6orf201 35 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | C35H6orf201 34 |
|
||
| C6orf201 35 |
|
OneToOne | |||
| cow (Bos Taurus) |
Mammalia | C23H6orf201 34 |
|
||
| C6orf201 35 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | RGD1307537 34 |
|
||
| mouse (Mus musculus) |
Mammalia | 4933417A18Rik 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | C6orf201 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | C6orf201 35 |
|
OneToOne |
- Species where no ortholog for C6orf201 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for C6orf201 Gene
No data available for Paralogs for C6orf201 Gene
Variants for C6orf201 Gene
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000085707 | -- | 4,078,013(+) | AACAG(C/T)CACTG | intron-variant, upstream-variant-2KB, utr-variant-5-prime | |
| rs1000086065 | -- | 4,101,237(+) | ATTTT(A/G)TTTTA | intron-variant | |
| rs1000217623 | -- | 4,110,985(+) | ATTTA(A/G)AAGTG | intron-variant | |
| rs1000273393 | -- | 4,099,638(+) | AGCAC(C/T)ATTGG | intron-variant | |
| rs1000428451 | -- | 4,084,728(+) | ACACC(C/T)TGCCT | intron-variant, utr-variant-5-prime |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2422231 | CNV | deletion | 17116639 |
| esv2422457 | CNV | deletion | 17116639 |
| esv3570734 | CNV | loss | 25503493 |
| nsv1140599 | CNV | deletion | 24896259 |
| nsv600860 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
90.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.24;
81.14% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for C6orf201 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C6orf201
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf201 Gene
Disorders for C6orf201 Gene
Relevant External Links for C6orf201
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- C6orf201
No disorders were found for C6orf201 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C6orf201 Gene
Publications for C6orf201 Gene
- Protein array based interactome analysis of amyloid-I^ indicates an inhibition of protein translation. (PMID: 21244100) Virok D.P. … FA1lAPp L. (J. Proteome Res. 2011) 3 64
- Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3 64
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
- The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 4 64
Products for C6orf201 Gene
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- Custom Antibody ServicesOriGene Antibodies for C6orf201
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- OriGene Purified Proteins for C6orf201
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- OriGene qPCR primer pairs for C6orf201
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- Novus Biologicals Antibodies for C6orf201
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- ViGene Biosciences adenoviral particle packaged cDNA for C6orf201 gene
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- Santa Cruz Biotechnology (SCBT) Antibodies for C6orf201
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- Santa Cruz Biotechnology (SCBT) CRISPR for C6orf201
- Horizon Cell Lines for C6orf201
- Cyagen custom Knockout/knockin (KOKI) mouse models for C6orf201
- VectorBuilder custom plasmid, inducible vectors for C6orf201
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C6orf201
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for C6orf201 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
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- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
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- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer