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Aliases for C6orf201 Gene

Aliases for C6orf201 Gene

  • Chromosome 6 Open Reading Frame 201 2 3 5
  • Uncharacterized Protein C6orf201 3
  • Protein MGC87625 3
  • DJ1013A10.5 3

External Ids for C6orf201 Gene

Previous GeneCards Identifiers for C6orf201 Gene

  • GC00U914401
  • GC06U900580
  • GC06P004025
  • GC06P003955

Summaries for C6orf201 Gene

GeneCards Summary for C6orf201 Gene

C6orf201 (Chromosome 6 Open Reading Frame 201) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf201 Gene

Genomics for C6orf201 Gene

Regulatory Elements for C6orf201 Gene

Enhancers for C6orf201 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F004133 1.1 ENCODE 27.4 +56.0 56025 3.8 HDGF CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF766 C6orf201 FAM217A ECI2 GC06P004132 ENSG00000254821
GH06F004188 0.6 FANTOM5 40.2 +109.8 109779 0.1 SCRT1 CBX3 SCRT2 NRF1 ZBTB33 C6orf201 FAM217A LOC100129052 LOC100507506
GH06F004125 0.8 ENCODE 21.4 +47.1 47124 2.1 CTCF SAP130 JUN CEBPG RAD21 RARA TEAD3 FOSL1 SMC3 NR2F6 C6orf201 ECI2 GC06P004125 GC06P004132
GH06F004055 0.8 ENCODE 16.6 -23.5 -23498 1.3 CTCF PKNOX1 RAD21 TEAD3 FOSL1 SLC30A9 FOXK2 SMC3 TRIM24 ZNF600 ENSG00000230648 C6orf201 FAM217A PRPF4B GC06M004041 GC06M004066
GH06F004109 0.9 ENCODE 11.8 +30.5 30476 0.2 ELF3 INSM2 FEZF1 ZNF2 ZNF366 KLF7 ZNF391 ZNF362 OVOL3 TSHZ1 LOC100507506 ENSG00000254821 ECI2 FAM217A C6orf201 GC06P004125 GC06M004088
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C6orf201 on UCSC Golden Path with GeneCards custom track

Genomic Location for C6orf201 Gene

Chromosome:
6
Start:
4,079,206 bp from pter
End:
4,130,951 bp from pter
Size:
51,746 bases
Orientation:
Plus strand

Genomic View for C6orf201 Gene

Genes around C6orf201 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C6orf201 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C6orf201 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C6orf201 Gene

Proteins for C6orf201 Gene

  • Protein details for C6orf201 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z4U5-CF201_HUMAN
    Recommended name:
    Uncharacterized protein C6orf201
    Protein Accession:
    Q7Z4U5
    Secondary Accessions:
    • A6NLI6
    • Q6NXN5

    Protein attributes for C6orf201 Gene

    Size:
    140 amino acids
    Molecular mass:
    16243 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C6orf201 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C6orf201 Gene

Post-translational modifications for C6orf201 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C6orf201 Gene

No data available for DME Specific Peptides for C6orf201 Gene

Domains & Families for C6orf201 Gene

Protein Domains for C6orf201 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C6orf201 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C6orf201: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C6orf201 Gene

Function for C6orf201 Gene

genes like me logo Genes that share phenotypes with C6orf201: view

Animal Model Products

miRNA for C6orf201 Gene

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C6orf201 Gene

Localization for C6orf201 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C6orf201 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C6orf201 Gene

Pathways & Interactions for C6orf201 Gene

SuperPathways for C6orf201 Gene

No Data Available

Interacting Proteins for C6orf201 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000420610%0d%0a9606.ENSP00000362931%0d%0a
Selected Interacting proteins: ENSP00000420610 Q7Z4U5-CF201_HUMAN for C6orf201 Gene via STRING IID

Gene Ontology (GO) - Biological Process for C6orf201 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C6orf201 Gene

Transcripts for C6orf201 Gene

Unigene Clusters for C6orf201 Gene

Chromosome 6 open reading frame 201:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C6orf201 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b
SP1: -
SP2:
SP3: - - - -
SP4: - -

Relevant External Links for C6orf201 Gene

GeneLoc Exon Structure for
C6orf201
ECgene alternative splicing isoforms for
C6orf201

Expression for C6orf201 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C6orf201 Gene

mRNA differential expression in normal tissues according to GTEx for C6orf201 Gene

This gene is overexpressed in Testis (x43.5).

Protein differential expression in normal tissues from HIPED for C6orf201 Gene

This gene is overexpressed in Pancreas (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C6orf201 Gene



Protein tissue co-expression partners for C6orf201 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C6orf201 Gene:

C6orf201

SOURCE GeneReport for Unigene cluster for C6orf201 Gene:

Hs.716731
genes like me logo Genes that share expression patterns with C6orf201: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C6orf201 Gene

Orthologs for C6orf201 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C6orf201 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C6H6orf201 34
  • 98.33 (n)
C6orf201 35
  • 80 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C35H6orf201 34
  • 77.89 (n)
C6orf201 35
  • 17 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C23H6orf201 34
  • 66.67 (n)
C6orf201 35
  • 33 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1307537 34
  • 66.17 (n)
mouse
(Mus musculus)
Mammalia 4933417A18Rik 34 16 35
  • 64.51 (n)
oppossum
(Monodelphis domestica)
Mammalia C6orf201 35
  • 18 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C6orf201 35
  • 18 (a)
OneToOne
Species where no ortholog for C6orf201 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C6orf201 Gene

ENSEMBL:
Gene Tree for C6orf201 (if available)
TreeFam:
Gene Tree for C6orf201 (if available)

Paralogs for C6orf201 Gene

No data available for Paralogs for C6orf201 Gene

Variants for C6orf201 Gene

Sequence variations from dbSNP and Humsavar for C6orf201 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs10080424 -- 4,079,347(+) CCGCC(C/G)GGCCT intron-variant, nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime
rs101418 -- 4,083,038(+) AGCCT(C/T)AGCTT intron-variant
rs10537375 -- 4,079,974(+) TCTCT(-/CTCT)ATCTA intron-variant, upstream-variant-2KB
rs10600703 -- 4,079,969(+) AAGAA(-/TCTC)TCTCT intron-variant, upstream-variant-2KB
rs10600748 -- 4,078,071(+) TTTTT(-/T)GAGAC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C6orf201 Gene

Variant ID Type Subtype PubMed ID
nsv600860 CNV loss 21841781
nsv1140599 CNV deletion 24896259
esv3570734 CNV loss 25503493
esv2422457 CNV deletion 17116639
esv2422231 CNV deletion 17116639

Variation tolerance for C6orf201 Gene

Residual Variation Intolerance Score: 90.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.24; 81.14% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C6orf201 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C6orf201

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf201 Gene

Disorders for C6orf201 Gene

Relevant External Links for C6orf201

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C6orf201

No disorders were found for C6orf201 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C6orf201 Gene

Publications for C6orf201 Gene

  1. Protein array based interactome analysis of amyloid-I^ indicates an inhibition of protein translation. (PMID: 21244100) Virok D.P. … FA1lAPp L. (J. Proteome Res. 2011) 3 64
  2. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3 64
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 4 64

Products for C6orf201 Gene

Sources for C6orf201 Gene

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