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Aliases for C6orf15 Gene

Aliases for C6orf15 Gene

  • Chromosome 6 Open Reading Frame 15 2 3 5
  • STG 3 4
  • Taste Bud-Specific Protein 3
  • Protein STG 4

External Ids for C6orf15 Gene

Previous GeneCards Identifiers for C6orf15 Gene

  • GC06M031135
  • GC06M030849
  • GC06M031185
  • GC06M031186

Summaries for C6orf15 Gene

GeneCards Summary for C6orf15 Gene

C6orf15 (Chromosome 6 Open Reading Frame 15) is a Protein Coding gene. Diseases associated with C6orf15 include peeling skin syndrome. GO annotations related to this gene include heparin binding and fibronectin binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf15 Gene

Genomics for C6orf15 Gene

Regulatory Elements for C6orf15 Gene

Genomic Location for C6orf15 Gene

31,111,223 bp from pter
31,112,559 bp from pter
1,337 bases
Minus strand

Genomic View for C6orf15 Gene

Genes around C6orf15 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C6orf15 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C6orf15 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for C6orf15 Gene

  • Protein details for C6orf15 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C6orf15
    Protein Accession:
    Secondary Accessions:
    • B0S7V8
    • Q0EFA6
    • Q2L6G7
    • Q5SQ81
    • Q86Z05
    • Q9UIG3

    Protein attributes for C6orf15 Gene

    325 amino acids
    Molecular mass:
    34195 Da
    Quaternary structure:
    • Binds to numerous extracellular matrix proteins.

neXtProt entry for C6orf15 Gene

Proteomics data for C6orf15 Gene at MOPED

Post-translational modifications for C6orf15 Gene

No Post-translational modifications

Other Protein References for C6orf15 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C6orf15 Gene

Domains & Families for C6orf15 Gene

Protein Domains for C6orf15 Gene


Suggested Antigen Peptide Sequences for C6orf15 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C6orf15: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C6orf15 Gene

Function for C6orf15 Gene

Gene Ontology (GO) - Molecular Function for C6orf15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001968 fibronectin binding IEA --
GO:0005540 hyaluronic acid binding IEA --
GO:0008201 heparin binding IEA --
GO:0043236 laminin binding IEA --
genes like me logo Genes that share ontologies with C6orf15: view

Phenotypes for C6orf15 Gene

genes like me logo Genes that share phenotypes with C6orf15: view

Animal Model Products

CRISPR Products

miRNA for C6orf15 Gene

miRTarBase miRNAs that target C6orf15

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C6orf15 Gene

Localization for C6orf15 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C6orf15 Gene

Secreted, extracellular space, extracellular matrix.

Subcellular locations from

Jensen Localization Image for C6orf15 Gene COMPARTMENTS Subcellular localization image for C6orf15 gene
Compartment Confidence
extracellular 3
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for C6orf15 Gene

Pathways & Interactions for C6orf15 Gene

SuperPathways for C6orf15 Gene

No Data Available

Interacting Proteins for C6orf15 Gene

Selected Interacting proteins: Q6UXA7-CF015_HUMAN for C6orf15 Gene via I2D

Gene Ontology (GO) - Biological Process for C6orf15 Gene


No data available for Pathways by source and SIGNOR curated interactions for C6orf15 Gene

Drugs & Compounds for C6orf15 Gene

No Compound Related Data Available

Transcripts for C6orf15 Gene

mRNA/cDNA for C6orf15 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C6orf15 Gene

Chromosome 6 open reading frame 15:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C6orf15 Gene

No ASD Table

Relevant External Links for C6orf15 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C6orf15 Gene

mRNA expression in normal human tissues for C6orf15 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C6orf15 Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x23.3), Skin - Not Sun Exposed (Suprapubic) (x13.5), Cervix - Endocervix (x4.6), and Vagina (x4.5).

Protein differential expression in normal tissues from HIPED for C6orf15 Gene

This gene is overexpressed in Milk (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C6orf15 Gene

SOURCE GeneReport for Unigene cluster for C6orf15 Gene Hs.272214

mRNA Expression by UniProt/SwissProt for C6orf15 Gene

Tissue specificity: Expressed in skin and tonsils.
genes like me logo Genes that share expression patterns with C6orf15: view

Protein tissue co-expression partners for C6orf15 Gene

Primer Products

In Situ Assay Products

Orthologs for C6orf15 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C6orf15 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C23H6orf15 35
  • 77.82 (n)
  • 64.14 (a)
C6orf15 36
  • 64 (a)
(Canis familiaris)
Mammalia C12H6orf15 35
  • 78.35 (n)
  • 65.81 (a)
C6ORF15 36
  • 66 (a)
(Mus musculus)
Mammalia 2300002M23Rik 35
  • 66.43 (n)
  • 50.9 (a)
2300002M23Rik 16
2300002M23Rik 36
  • 43 (a)
(Pan troglodytes)
Mammalia C6H6orf15 35
  • 98.77 (n)
  • 98.77 (a)
C6H6orf15 36
  • 96 (a)
(Rattus norvegicus)
Mammalia RGD1562885 35
  • 69.58 (n)
  • 53.45 (a)
Species with no ortholog for C6orf15:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C6orf15 Gene

Gene Tree for C6orf15 (if available)
Gene Tree for C6orf15 (if available)

Paralogs for C6orf15 Gene

No data available for Paralogs for C6orf15 Gene

Variants for C6orf15 Gene

Sequence variations from dbSNP and Humsavar for C6orf15 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
VAR_022907 -
VAR_022908 -
VAR_022909 -
VAR_022910 -
VAR_028732 -

Structural Variations from Database of Genomic Variants (DGV) for C6orf15 Gene

Variant ID Type Subtype PubMed ID
esv2731791 CNV Deletion 23290073
dgv1918e1 CNV Complex 17122850
dgv1919e1 CNV Complex 17122850
nsv428140 CNV Gain+Loss 18775914
esv690 CNV CNV 17122850

Variation tolerance for C6orf15 Gene

Residual Variation Intolerance Score: 86% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.08; 80.42% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C6orf15 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf15 Gene

Disorders for C6orf15 Gene

MalaCards: The human disease database

(1) MalaCards diseases for C6orf15 Gene - From: DISEASES

Disorder Aliases PubMed IDs
peeling skin syndrome
  • peeling skin syndrome 1
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for C6orf15

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C6orf15: view

No data available for UniProtKB/Swiss-Prot and Genatlas for C6orf15 Gene

Publications for C6orf15 Gene

  1. STG does not associate with psoriasis in the Swedish population. (PMID: 15217361) Sanchez F. … Staehle M. (Exp. Dermatol. 2004) 2 3 4 67
  2. GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. (PMID: 23263863) Li J. … Sleiman P.M. (Hum. Mol. Genet. 2013) 3
  3. A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1). (PMID: 23326239) Rubicz R. … GAPring H.H. (PLoS Genet. 2013) 3
  4. Novel associations for hypothyroidism include known autoimmune risk loci. (PMID: 22493691) Eriksson N. … Do C.B. (PLoS ONE 2012) 3
  5. Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy. (PMID: 21323541) Stanescu H.C. … Kleta R. (N. Engl. J. Med. 2011) 3

Products for C6orf15 Gene

Sources for C6orf15 Gene

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