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Aliases for C6orf141 Gene

Aliases for C6orf141 Gene

  • Chromosome 6 Open Reading Frame 141 2 3 5

External Ids for C6orf141 Gene

Previous GeneCards Identifiers for C6orf141 Gene

  • GC06P049519
  • GC06P049565
  • GC06P049626
  • GC06P049247

Summaries for C6orf141 Gene

GeneCards Summary for C6orf141 Gene

C6orf141 (Chromosome 6 Open Reading Frame 141) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf141 Gene

Genomics for C6orf141 Gene

Regulatory Elements for C6orf141 Gene

Enhancers for C6orf141 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around C6orf141 on UCSC Golden Path with GeneCards custom track

Promoters for C6orf141 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C6orf141 on UCSC Golden Path with GeneCards custom track

Genomic Location for C6orf141 Gene

49,550,400 bp from pter
49,561,907 bp from pter
11,508 bases
Plus strand

Genomic View for C6orf141 Gene

Genes around C6orf141 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C6orf141 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C6orf141 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C6orf141 Gene

Proteins for C6orf141 Gene

  • Protein details for C6orf141 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C6orf141
    Protein Accession:
    Secondary Accessions:
    • A8K1H4
    • Q8N400
    • Q96NQ1

    Protein attributes for C6orf141 Gene

    244 amino acids
    Molecular mass:
    26754 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH36917.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for C6orf141 Gene

Post-translational modifications for C6orf141 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C6orf141 Gene

No data available for DME Specific Peptides for C6orf141 Gene

Domains & Families for C6orf141 Gene

Protein Domains for C6orf141 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C6orf141: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C6orf141 Gene

Function for C6orf141 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C6orf141 Gene

Localization for C6orf141 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C6orf141 Gene

Pathways & Interactions for C6orf141 Gene

SuperPathways for C6orf141 Gene

No Data Available

Interacting Proteins for C6orf141 Gene

Selected Interacting proteins: Q5SZD1-CF141_HUMAN for C6orf141 Gene via IID

Gene Ontology (GO) - Biological Process for C6orf141 Gene


No data available for Pathways by source and SIGNOR curated interactions for C6orf141 Gene

Drugs & Compounds for C6orf141 Gene

No Compound Related Data Available

Transcripts for C6orf141 Gene

mRNA/cDNA for C6orf141 Gene

Unigene Clusters for C6orf141 Gene

Chromosome 6 open reading frame 141:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C6orf141 Gene

No ASD Table

Relevant External Links for C6orf141 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C6orf141 Gene

mRNA expression in normal human tissues for C6orf141 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C6orf141 Gene

This gene is overexpressed in Brain - Nucleus accumbens (basal ganglia) (x6.4), Brain - Putamen (basal ganglia) (x6.2), and Brain - Caudate (basal ganglia) (x5.8).

Protein differential expression in normal tissues from HIPED for C6orf141 Gene

This gene is overexpressed in Plasma (56.1) and Heart (12.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C6orf141 Gene

Protein tissue co-expression partners for C6orf141 Gene

NURSA nuclear receptor signaling pathways regulating expression of C6orf141 Gene:


SOURCE GeneReport for Unigene cluster for C6orf141 Gene:

genes like me logo Genes that share expression patterns with C6orf141: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for C6orf141 Gene

Orthologs for C6orf141 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C6orf141 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C23H6orf141 34
  • 72.19 (n)
  • 59.89 (a)
C23H6orf141 35
  • 57 (a)
(Mus musculus)
Mammalia 9130008F23Rik 34
  • 64.15 (n)
  • 53.46 (a)
9130008F23Rik 16
9130008F23Rik 35
  • 48 (a)
(Pan troglodytes)
Mammalia C6H6orf141 34
  • 98.91 (n)
  • 97.54 (a)
C6orf141 35
  • 97 (a)
(Rattus norvegicus)
Mammalia LOC688459 34
  • 65.92 (n)
  • 54.49 (a)
(Canis familiaris)
Mammalia C6orf141 35
  • 47 (a)
(Ornithorhynchus anatinus)
Mammalia C6orf141 35
  • 38 (a)
Species where no ortholog for C6orf141 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C6orf141 Gene

Gene Tree for C6orf141 (if available)
Gene Tree for C6orf141 (if available)

Paralogs for C6orf141 Gene

No data available for Paralogs for C6orf141 Gene

Variants for C6orf141 Gene

Sequence variations from dbSNP and Humsavar for C6orf141 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs6919674 - 49,551,201(+) AACGA(C/G)AAAAG reference, missense
rs9473588 - 49,551,496(+) GTCTC(C/T)AGGGA reference, missense
rs4711929 -- 49,560,595(+) ctccc(A/G)ggttc downstream-variant-500B
rs6458697 -- 49,557,793(+) gtctc(A/G)tagtt intron-variant
rs6458698 -- 49,558,064(+) gtttt(G/T)ttttt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C6orf141 Gene

Variant ID Type Subtype PubMed ID
dgv5960n100 CNV gain 25217958

Variation tolerance for C6orf141 Gene

Gene Damage Index Score: 4.76; 66.58% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C6orf141 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf141 Gene

Disorders for C6orf141 Gene

Relevant External Links for C6orf141

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C6orf141 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C6orf141 Gene

Publications for C6orf141 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  3. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4 65
  4. Phospho-tyrosine dependent protein-protein interaction network. (PMID: 25814554) Grossmann A. … Stelzl U. (Mol. Syst. Biol. 2015) 3 65
  5. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3 65

Products for C6orf141 Gene

Sources for C6orf141 Gene