C6orf132 Gene
protein-coding GIFtS : 34
GCID: GC06 M042069 (predicted)
chromosome 6 open reading frame 132
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Aliasesfor C6orf132 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Chromosome 6 Open Reading Frame 132 1 2 BA7K24.21 Uncharacterized Protein C6orf1322
Export aliases for C6orf132 gene to outside databases Previous GC identifers: GC00U914215 GC06U900651 GC06M042185 GC06M042202 GC06M041786
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Summariesfor C6orf132 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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Genomic Viewsfor C6orf132 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000006.11 NC_018917.1 NT_007592.15 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the C6orf132 gene promoter: Bach1 GATA-3 GATA-1 GATA-2 RORalpha1 HOXA5 FOXO1a LyF-1 ATF6 FOXO1 Other transcription factors Search SABiosciences Chromatin IP Primers for C6orf132 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat C6orf132
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 6p21.1 Ensembl cytogenetic band: 6p21.1 HGNC cytogenetic band: 6p21.1 C6orf132 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 6 GeneLoc Exon Structure
GeneLoc location for GC06M042069: view genomic region
(about GC identifiers )
Start:
42,068,856 bp from pter
End:
42,110,715 bp from pter
Size:
41,860 bases
Orientation:
minus strand
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Proteinsfor C6orf132 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: CF132_HUMAN, Q5T0Z8 (See
protein sequence )Recommended Name: Uncharacterized protein C6orf132 Size : 1188 amino acids; 124034 Da
Sequence caution : Sequence=BE791477; Type=Frameshift; Positions=Several; Sequence=BU857282; Type=Miscellaneousdiscrepancy; Note=Contaminating sequence. Sequence of unknown origin in the N-terminal part; Sequence=BU857282; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the C-terminal part; Sequence=CAI16783.1; Type=Erroneous gene model prediction; Sequence=CAI19541.1; Type=Erroneous gene model prediction;
Secondary accessions : A6NI05Alternative splicing : 3 isoforms : Q5T0Z8-1 Q5T0Z8-2 Q5T0Z8-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for C6orf132: NX_Q5T0Z8 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q5T0Z8 C6orf132 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins: NP_001157918.1 ENSEMBL proteins: ENSP00000341368 ENSP00000348941 Human Recombinant Protein Products for C6orf132: C6orf132 Antibody Products: Assay Products for C6orf132:
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Protein
Domains / Familiesfor C6orf132 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section ProtoNet protein and cluster: Q5T0Z8
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Functionfor C6orf132 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Phenotypes: 2 GenomeRNAi human phenotypes for C6orf132 :Animal Models: Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for C6orf132 (see all 2 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for C6orf132OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: C6orf132 (NM_001164446 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C6orf132 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C6orf132
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C6orf132
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Pathways & Interactionsfor C6orf132 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C6orf132
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Drugs & Compoundsfor C6orf132 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for C6orf132 Search CenterWatch for drugs/clinical trials and news about C6orf132 / CF132
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Transcriptsfor C6orf132 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for C6orf132 gene: NM_001164446.1 Unigene Cluster for C6orf132:
Chromosome 6 open reading frame 132 Hs.444277 [show with all ESTs ] Unigene Representative Sequence: NM_001164446 2 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000341865 (uc003orw.2 ) ENST00000356542 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for C6orf132 (see all 2 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for C6orf132OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: C6orf132 (NM_001164446 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C6orf132 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C6orf132
Additional cDNA sequence: AK074567.1
7 DOTS entries : DT.91654175 DT.70102458
DT.97835209 DT.70105079 DT.75170715 DT.91811386 DT.95153158 GeneLoc Exon Structure
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Expression for C6orf132 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section C6orf132 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: -- About this image C6orf132 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table
Stem Cell Differentiation: 2 LifeMap Cells Name Category PureStem™ progenitor EN2 (Embryonic Progenitor Cell)ES04(HES-4) (Embryonic Stem Cell)Early Embryo, Inner Cell Mass Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
See C6orf132 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for C6orf132 SOURCE GeneReport for Unigene cluster: Hs.444277 SABiosciences Custom PCR Arrays for C6orf132 Primer Products: Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse / rat C6orf132 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat C6orf132 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat C6orf132 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C6orf132
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Orthologsfor C6orf132 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for C6orf132 gene from 2/7 species (see all 7 ) About this table
ENSEMBL Gene Tree for C6orf132 (if available)TreeFam Gene Tree for C6orf132 (if available)
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Paralogsfor C6orf132 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor C6orf132 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 6 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for C6orf132 (42068856 - 42110715 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for C6orf132 1 CNV : 53255
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing C6orf132
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Disorders
/ Diseasesfor C6orf132 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section --
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Publicationsfor C6orf132 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for C6orf132 gene integrated from 9 sources : (articles sorted by number of sources associating them with C6orf132) Utopia : connect your pdf to the dynamic world of online information
Initial characterization of the human central proteome. (PubMed id 21269460) 2 Burkard T.R.... Colinge J. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692) 2 Rigbolt K.T....Blagoev B. (2011) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231) 2 Olsen J.V....Mann M. (2010) The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005) 2 Bechtel S.... Schupp I. (2007) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 2 Ota T.... Sugano S. (2004) The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404) 2 Mungall A.J.... Beck S. (2003) Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id ) 2 Aoki H.... Hino O. (2000)
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External Searches for C6orf132 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing C6orf132 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing C6orf132 gene
(According to HUGE )
About This Section --
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Specialized Databases showing C6orf132 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for C6orf132 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for C6orf132 gene: Search GeneIP for patents involving C6orf132 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor C6orf132 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies Browse OriGene shRNA RFPs OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for C6orf132 Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for C6orf132 OriGene 3'-UTR Clone for C6orf132 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for C6orf132 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for C6orf132 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for C6orf132 OriGene Custom Protein Services for C6orf132 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C6orf132 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing C6orf132 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat C6orf132 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat C6orf132 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat C6orf132 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat C6orf132
C6orf132 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C6orf132
Search ThermoFisher Antibodies for C6orf132
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C6orf132
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