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Aliases for C6orf132 Gene

Aliases for C6orf132 Gene

  • Chromosome 6 Open Reading Frame 132 2 3 5
  • Uncharacterized Protein C6orf132 3
  • BA7K24.2 3

External Ids for C6orf132 Gene

Previous GeneCards Identifiers for C6orf132 Gene

  • GC00U914215
  • GC06U900651
  • GC06M042185
  • GC06M042202
  • GC06M041786

Summaries for C6orf132 Gene

GeneCards Summary for C6orf132 Gene

C6orf132 (Chromosome 6 Open Reading Frame 132) is a Protein Coding gene.

Additional gene information for C6orf132 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf132 Gene

Genomics for C6orf132 Gene

Regulatory Elements for C6orf132 Gene

Enhancers for C6orf132 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06H042097 1.6 Ensembl ENCODE dbSUPER 18.1 +40.1 40117 11.2 HNRNPUL1 HDGF PKNOX1 MLX ARID4B SLC30A9 ZNF766 ZNF143 FOS SP5 RRP36 C6orf132 UBR2 BICRAL GUCA1A ENSG00000214732 GUCA1B ENSG00000261068 FRS3 ENSG00000124593
GH06H042115 1.5 Ensembl ENCODE dbSUPER 18.4 +22.2 22167 10.1 FOXA2 ARID4B SIN3A DMAP1 YY1 ZNF121 ZNF207 FOS SP5 REST MED20 C6orf132 ENSG00000214732 GUCA1A GUCA1B ENSG00000207371 BYSL ENSG00000206977 ENSG00000261068 GC06P042135
GH06H042112 1 ENCODE dbSUPER 26.9 +29.3 29262 2.8 LEF1 ZNF362 SOX6 CEBPG PPARG OSR2 ZFHX2 PRDM6 ZNF692 FOS C6orf132 GUCA1A ENSG00000214732 GUCA1B MED20 ENSG00000207371 BYSL ENSG00000261068 GC06P042135
GH06H042223 1.6 Ensembl ENCODE dbSUPER 10.3 -83.8 -83825 5.9 HDGF PKNOX1 ARID4B SIN3A FEZF1 ZBTB7B FOS SP3 JUNB SMARCB1 MRPS10 GUCA1B ENSG00000214732 GUCA1A C6orf132 PIR36094
GH06H041766 1.3 Ensembl ENCODE 11.6 +374.9 374878 3.3 HDGF PKNOX1 FEZF1 ZNF2 ZNF302 SP3 REST ZNF592 KAT8 ZNF610 MED20 OARD1 C6orf132 MDFI USP49 PGC ENSG00000124593 ENSG00000269387 PIR31477
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C6orf132 on UCSC Golden Path with GeneCards custom track

Promoters for C6orf132 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000196938 677 1001 ZFP64 ZNF76 KLF17 ZNF121 GLIS2 SCRT2 KLF7 EGR2 SP3 ZNF680

Genomic Locations for C6orf132 Gene

Genomic Locations for C6orf132 Gene
41,860 bases
Minus strand

Genomic View for C6orf132 Gene

Genes around C6orf132 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C6orf132 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C6orf132 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C6orf132 Gene

Proteins for C6orf132 Gene

  • Protein details for C6orf132 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C6orf132
    Protein Accession:
    Secondary Accessions:
    • A6NI05

    Protein attributes for C6orf132 Gene

    1188 amino acids
    Molecular mass:
    124034 Da
    Quaternary structure:
    No Data Available
    • Sequence=BE791477; Type=Frameshift; Positions=Several; Evidence={ECO:0000305}; Sequence=BU857282; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the N-terminal part.; Evidence={ECO:0000305}; Sequence=BU857282; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the C-terminal part.; Evidence={ECO:0000305}; Sequence=CAI16783.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI19541.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for C6orf132 Gene


neXtProt entry for C6orf132 Gene

Post-translational modifications for C6orf132 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C6orf132 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C6orf132 Gene

Domains & Families for C6orf132 Gene

Gene Families for C6orf132 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C6orf132 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C6orf132: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C6orf132 Gene

Function for C6orf132 Gene

Phenotypes From GWAS Catalog for C6orf132 Gene

genes like me logo Genes that share phenotypes with C6orf132: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C6orf132 Gene

Localization for C6orf132 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C6orf132 gene
Compartment Confidence
cytosol 3
mitochondrion 2
nucleus 2
golgi apparatus 2
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Golgi apparatus (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C6orf132 Gene

Pathways & Interactions for C6orf132 Gene

SuperPathways for C6orf132 Gene

No Data Available

Interacting Proteins for C6orf132 Gene

STRING Interaction Network Preview (showing 4 interactants - click image to see details)
Selected Interacting proteins: ENSP00000341368 for C6orf132 Gene via STRING

Gene Ontology (GO) - Biological Process for C6orf132 Gene


No data available for Pathways by source and SIGNOR curated interactions for C6orf132 Gene

Drugs & Compounds for C6orf132 Gene

No Compound Related Data Available

Transcripts for C6orf132 Gene

mRNA/cDNA for C6orf132 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C6orf132 Gene

Chromosome 6 open reading frame 132:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C6orf132 Gene

No ASD Table

Relevant External Links for C6orf132 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C6orf132 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C6orf132 Gene

mRNA differential expression in normal tissues according to GTEx for C6orf132 Gene

This gene is overexpressed in Esophagus - Mucosa (x13.8), Skin - Sun Exposed (Lower leg) (x6.3), Skin - Not Sun Exposed (Suprapubic) (x6.0), and Vagina (x4.5).

Protein differential expression in normal tissues from HIPED for C6orf132 Gene

This gene is overexpressed in Cervix (34.2), Bone (12.9), and Hair follicle (10.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C6orf132 Gene

NURSA nuclear receptor signaling pathways regulating expression of C6orf132 Gene:


SOURCE GeneReport for Unigene cluster for C6orf132 Gene:

genes like me logo Genes that share expression patterns with C6orf132: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C6orf132 Gene

Orthologs for C6orf132 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C6orf132 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C6H6orf132 33
  • 98.89 (n)
C6orf132 34
  • 98 (a)
(Canis familiaris)
Mammalia C6orf132 34
  • 71 (a)
(Mus musculus)
Mammalia AI661453 34
  • 65 (a)
(Bos Taurus)
Mammalia C6orf132 34
  • 57 (a)
(Ornithorhynchus anatinus)
Mammalia C6orf132 34
  • 53 (a)
(Monodelphis domestica)
Mammalia C6orf132 34
  • 26 (a)
(Gallus gallus)
Aves C6orf132 34
  • 34 (a)
(Anolis carolinensis)
Reptilia C6orf132 34
  • 47 (a)
Species where no ortholog for C6orf132 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C6orf132 Gene

Gene Tree for C6orf132 (if available)
Gene Tree for C6orf132 (if available)

Paralogs for C6orf132 Gene

No data available for Paralogs for C6orf132 Gene

Variants for C6orf132 Gene

Sequence variations from dbSNP and Humsavar for C6orf132 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000091995 -- 42,129,205(+) CATGC(A/G)GAGCA intron-variant
rs1000168309 -- 42,131,768(+) ATTGT(C/T)GTTTT intron-variant
rs1000176416 -- 42,101,556(+) GTCCA(A/T)ACTGG utr-variant-3-prime
rs1000188940 -- 42,121,238(+) GCTCC(A/G)GGCAC intron-variant
rs1000268462 -- 42,104,892(+) GGCGG(C/T)CCAGA reference, missense

Structural Variations from Database of Genomic Variants (DGV) for C6orf132 Gene

Variant ID Type Subtype PubMed ID
nsv830649 CNV loss 17160897
esv2658537 CNV deletion 23128226
dgv753n27 CNV loss 19166990
dgv10639n54 CNV loss 21841781

Variation tolerance for C6orf132 Gene

Gene Damage Index Score: 8.73; 86.61% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C6orf132 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf132 Gene

Disorders for C6orf132 Gene

Relevant External Links for C6orf132

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C6orf132 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C6orf132 Gene

Publications for C6orf132 Gene

  1. Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations. (PMID: 24529757) Xie T … Xu R (Neurobiology of aging 2014) 3 60
  2. E-cadherin interactome complexity and robustness resolved by quantitative proteomics. (PMID: 25468996) Guo Z … Zaidel-Bar R (Science signaling 2014) 3 60
  3. Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. (PMID: 24129315) Guo A … Comb MJ (Molecular & cellular proteomics : MCP 2014) 4 60
  4. Initial characterization of the human central proteome. (PMID: 21269460) Burkard TR … Colinge J (BMC systems biology 2011) 4 60
  5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PMID: 21406692) Rigbolt KT … Blagoev B (Science signaling 2011) 4 60

Products for C6orf132 Gene

Sources for C6orf132 Gene

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