Aliases for C6orf132 Gene
Aliases for C6orf132 Gene
External Ids for C6orf132 Gene
- HGNC: 21288
- Entrez Gene: 647024
- Ensembl: ENSG00000188112
- UniProtKB: Q5T0Z8
Previous GeneCards Identifiers for C6orf132 Gene
- GC00U914215
- GC06U900651
- GC06M042185
- GC06M042202
- GC06M041786
Summaries for C6orf132 Gene
GeneCards Summary for C6orf132 Gene
C6orf132 (Chromosome 6 Open Reading Frame 132) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf132 Gene
Genomics for C6orf132 Gene
Regulatory Elements for C6orf132 Gene
Enhancers for C6orf132 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around C6orf132 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for C6orf132 Gene
- Chromosome:
- 6
- Start:
- 42,101,118 bp from pter
- End:
- 42,142,977 bp from pter
- Size:
- 41,860 bases
- Orientation:
- Minus strand
Genomic View for C6orf132 Gene
Genes around C6orf132 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p21.1 by Ensembl
- 6p21.1 by Entrez Gene
- 6p21.1 by HGNC
C6orf132 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C6orf132 Gene
Proteins for C6orf132 Gene
-
Protein details for C6orf132 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5T0Z8-CF132_HUMAN
- Recommended name:
- Uncharacterized protein C6orf132
- Protein Accession:
- Q5T0Z8
- A6NI05
Protein attributes for C6orf132 Gene
- Size:
- 1188 amino acids
- Molecular mass:
- 124034 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BE791477; Type=Frameshift; Positions=Several; Evidence={ECO:0000305}; Sequence=BU857282; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the N-terminal part.; Evidence={ECO:0000305}; Sequence=BU857282; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the C-terminal part.; Evidence={ECO:0000305}; Sequence=CAI16783.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI19541.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Protein Expression for C6orf132 Gene
Post-translational modifications for C6orf132 Gene
Other Protein References for C6orf132 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for C6orf132
-
Abcam antibodies for C6orf132
- Invitrogen Antibodies for C6orf132
- Search GeneTex for Antibodies for C6orf132
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for C6orf132
- Origene Custom Protein Services for C6orf132
- Novus Biologicals proteins for C6orf132
- Search GeneTex for Proteins for C6orf132
Assay Products
No data available for DME Specific Peptides for C6orf132 Gene
Domains & Families for C6orf132 Gene
Protein Domains for C6orf132 Gene
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C6orf132 Gene
Function for C6orf132 Gene
Phenotypes for C6orf132 Gene
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for C6orf132 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for C6orf132 gene
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CRISPR Products
-
OriGene CRISPR knockouts for C6orf132
-
Santa Cruz Biotechnology (SCBT) CRISPR for C6orf132
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miRNA for C6orf132 Gene
- miRTarBase miRNAs that target C6orf132
-
- hsa-mir-335-5p (MIRT017346)
- hsa-mir-215-5p (MIRT529592)
- hsa-mir-192-5p (MIRT529593)
- hsa-mir-1193 (MIRT529594)
- hsa-mir-6821-3p (MIRT529595)
- hsa-mir-6790-3p (MIRT529596)
- hsa-mir-2392 (MIRT529597)
- hsa-mir-216b-5p (MIRT529598)
- hsa-mir-216a-5p (MIRT529599)
- hsa-mir-5096 (MIRT619704)
- hsa-mir-6855-5p (MIRT619705)
- hsa-mir-3170 (MIRT619706)
- hsa-mir-197-3p (MIRT619707)
- hsa-mir-411-5p (MIRT619708)
- hsa-mir-6832-5p (MIRT619709)
- hsa-mir-193b-5p (MIRT619710)
- hsa-mir-6721-5p (MIRT619711)
- hsa-mir-1273f (MIRT619712)
- hsa-mir-6890-5p (MIRT619713)
- hsa-mir-6783-3p (MIRT633130)
- hsa-mir-1343-3p (MIRT633131)
- hsa-mir-23b-5p (MIRT633132)
- hsa-mir-23a-5p (MIRT633133)
- hsa-mir-4772-3p (MIRT633134)
- hsa-mir-6742-3p (MIRT633135)
- hsa-mir-6852-5p (MIRT633136)
- hsa-mir-939-3p (MIRT633137)
- hsa-mir-660-3p (MIRT633138)
- hsa-mir-1306-5p (MIRT633139)
- hsa-mir-937-5p (MIRT646886)
- hsa-mir-6749-3p (MIRT646887)
- hsa-mir-211-5p (MIRT646888)
- hsa-mir-204-5p (MIRT646889)
- hsa-mir-5702 (MIRT646890)
- hsa-mir-4685-3p (MIRT646891)
- hsa-mir-4287 (MIRT646892)
- hsa-mir-6832-3p (MIRT646893)
- hsa-mir-4793-5p (MIRT646894)
- hsa-mir-5196-3p (MIRT646895)
- hsa-mir-3174 (MIRT646896)
- hsa-mir-19b-3p (MIRT675086)
- hsa-mir-19a-3p (MIRT675087)
- hsa-mir-4284 (MIRT675088)
- hsa-mir-4638-5p (MIRT675089)
- hsa-mir-1307-3p (MIRT675090)
- hsa-mir-1304-3p (MIRT675091)
- hsa-mir-6741-3p (MIRT675092)
- hsa-mir-6890-3p (MIRT675093)
miRNA Products
- Search ViGene Biosciences for C6orf132
Inhibitory RNA Products
- Origene RNAi and siRNA products in human, mouse, rat for C6orf132
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-
ViGene Biosciences ready-to-package AAV shRNAs for C6orf132 gene
Clone Products
-
OriGene ORF clones in human for C6orf132
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for C6orf132
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C6orf132
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for C6orf132
-
ViGene Biosciences adenoviral particle packaged cDNA for C6orf132 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for C6orf132 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for C6orf132 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C6orf132 Gene
Localization for C6orf132 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 3 |
| mitochondrion | 2 |
| nucleus | 2 |
| golgi apparatus | 2 |
| peroxisome | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C6orf132 Gene
Pathways & Interactions for C6orf132 Gene
No Data Available
Interacting Proteins for C6orf132 Gene
No data available for Pathways by source and SIGNOR curated interactions for C6orf132 Gene
Transcripts for C6orf132 Gene
mRNA/cDNA for C6orf132 Gene
- (1) REFSEQ mRNAs :
- (1) Additional mRNA sequences :
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for C6orf132 Gene
- Chromosome 6 open reading frame 132:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for C6orf132
-
Santa Cruz Biotechnology (SCBT) CRISPR for C6orf132
- GenScript: Design CRISPR guide RNA sequences for C6orf132
miRNA Products
- Search ViGene Biosciences for C6orf132
Inhibitory RNA Products
- Origene RNAi and siRNA products in human, mouse, rat for C6orf132
- Browse OriGene Inhibitory RNA Products For C6orf132
-
ViGene Biosciences ready-to-package AAV shRNAs for C6orf132 gene
Clone Products
-
OriGene ORF clones in human for C6orf132
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for C6orf132
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C6orf132
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for C6orf132 Gene
mRNA differential expression in normal tissues according to GTEx for C6orf132 Gene
This gene is overexpressed in Esophagus - Mucosa (x13.8), Skin - Sun Exposed (Lower leg) (x6.3), Skin - Not Sun Exposed (Suprapubic) (x6.0), and Vagina (x4.5).
This gene is overexpressed in Cervix (34.2), Bone (12.9), and Hair follicle (10.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C6orf132 Gene
NURSA nuclear receptor signaling pathways regulating expression of C6orf132 Gene:
C6orf132SOURCE GeneReport for Unigene cluster for C6orf132 Gene:
Hs.444277Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C6orf132 Gene
Orthologs for C6orf132 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C6H6orf132 34 |
|
||
| C6orf132 35 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | C6orf132 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | AI661453 35 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | C6orf132 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | C6orf132 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | C6orf132 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | C6orf132 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | C6orf132 35 |
|
OneToOne |
- Species where no ortholog for C6orf132 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for C6orf132 Gene
No data available for Paralogs for C6orf132 Gene
Variants for C6orf132 Gene
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000091995 | -- | 42,129,205(+) | CATGC(A/G)GAGCA | intron-variant | |
| rs1000168309 | -- | 42,131,768(+) | ATTGT(C/T)GTTTT | intron-variant | |
| rs1000176416 | -- | 42,101,556(+) | GTCCA(A/T)ACTGG | utr-variant-3-prime | |
| rs1000188940 | -- | 42,121,238(+) | GCTCC(A/G)GGCAC | intron-variant | |
| rs1000268462 | -- | 42,104,892(+) | GGCGG(C/T)CCAGA | reference, missense |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv10639n54 | CNV | loss | 21841781 |
| dgv753n27 | CNV | loss | 19166990 |
| esv2658537 | CNV | deletion | 23128226 |
| nsv830649 | CNV | loss | 17160897 |
Gene Damage Index Score:
8.73;
86.61% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for C6orf132 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf132 Gene
Disorders for C6orf132 Gene
Relevant External Links for C6orf132
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- C6orf132
No disorders were found for C6orf132 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C6orf132 Gene
Publications for C6orf132 Gene
- Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations. (PMID: 24529757) Xie T. … Xu R. (Neurobiol. Aging 2014) 3 64
- E-cadherin interactome complexity and robustness resolved by quantitative proteomics. (PMID: 25468996) Guo Z. … Zaidel-Bar R. (Sci Signal 2014) 3 64
- Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. (PMID: 24129315) Guo A. … Comb M.J. (Mol. Cell. Proteomics 2014) 4 64
- Initial characterization of the human central proteome. (PMID: 21269460) Burkard T.R. … Colinge J. (BMC Syst. Biol. 2011) 4 64
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PMID: 21406692) Rigbolt K.T. … Blagoev B. (Sci. Signal. 2011) 4 64
Products for C6orf132 Gene
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- Browse R&D Systems for biochemical assays
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- Novus Biologicals Antibodies for C6orf132
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- Novus Biologicals
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- Invitrogen Antibodies for C6orf132
- ViGene Biosciences adenoviral particle packaged cDNA for C6orf132 gene
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- Horizon Cell Lines for C6orf132
- Cyagen custom Knockout/knockin (KOKI) mouse models for C6orf132
- VectorBuilder custom plasmid, inducible vectors for C6orf132
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C6orf132
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for C6orf132 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
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- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
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- (130) MedlinePlus
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- (133) NCBI Bookshelf
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- (135) Gene Damage Index
- (136) ViGene Biosciences
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- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer