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Aliases for C6orf118 Gene

Aliases for C6orf118 Gene

  • Chromosome 6 Open Reading Frame 118 2 3 5
  • DJ416F21.2 (Novel Protein) 3
  • DJ416F21.2 3
  • BA85G2.1 3

External Ids for C6orf118 Gene

Previous GeneCards Identifiers for C6orf118 Gene

  • GC06M165526
  • GC06M165602
  • GC06M165663
  • GC06M163154
  • GC06M165693

Summaries for C6orf118 Gene

GeneCards Summary for C6orf118 Gene

C6orf118 (Chromosome 6 Open Reading Frame 118) is a Protein Coding gene. GO annotations related to this gene include RNA binding and ribonuclease activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf118 Gene

Genomics for C6orf118 Gene

Regulatory Elements for C6orf118 Gene

Promoters for C6orf118 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C6orf118 on UCSC Golden Path with GeneCards custom track

Genomic Location for C6orf118 Gene

Chromosome:
6
Start:
165,279,664 bp from pter
End:
165,309,647 bp from pter
Size:
29,984 bases
Orientation:
Minus strand

Genomic View for C6orf118 Gene

Genes around C6orf118 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C6orf118 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C6orf118 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C6orf118 Gene

Proteins for C6orf118 Gene

  • Protein details for C6orf118 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T5N4-CF118_HUMAN
    Recommended name:
    Uncharacterized protein C6orf118
    Protein Accession:
    Q5T5N4
    Secondary Accessions:
    • Q8TC11

    Protein attributes for C6orf118 Gene

    Size:
    469 amino acids
    Molecular mass:
    53772 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C6orf118 Gene

Proteomics data for C6orf118 Gene at MOPED

Post-translational modifications for C6orf118 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C6orf118 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C6orf118 Gene

Domains & Families for C6orf118 Gene

Protein Domains for C6orf118 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C6orf118: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C6orf118 Gene

Function for C6orf118 Gene

genes like me logo Genes that share phenotypes with C6orf118: view

Animal Model Products

CRISPR Products

miRNA for C6orf118 Gene

miRTarBase miRNAs that target C6orf118

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C6orf118 Gene

Localization for C6orf118 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C6orf118 Gene COMPARTMENTS Subcellular localization image for C6orf118 gene
Compartment Confidence
mitochondrion 3
cytosol 2
nucleus 2
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C6orf118 Gene

Pathways & Interactions for C6orf118 Gene

SuperPathways for C6orf118 Gene

No Data Available

Interacting Proteins for C6orf118 Gene

Gene Ontology (GO) - Biological Process for C6orf118 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C6orf118 Gene

Drugs & Compounds for C6orf118 Gene

No Compound Related Data Available

Transcripts for C6orf118 Gene

mRNA/cDNA for C6orf118 Gene

Unigene Clusters for C6orf118 Gene

Chromosome 6 open reading frame 118:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C6orf118 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b
SP1: - - -
SP2:
SP3:

Relevant External Links for C6orf118 Gene

GeneLoc Exon Structure for
C6orf118
ECgene alternative splicing isoforms for
C6orf118

Expression for C6orf118 Gene

mRNA expression in normal human tissues for C6orf118 Gene

mRNA differential expression in normal tissues according to GTEx for C6orf118 Gene

This gene is overexpressed in Testis (x13.5), Pituitary (x6.4), Brain - Caudate (basal ganglia) (x4.7), Fallopian Tube (x4.6), and Brain - Hypothalamus (x4.6).

Protein differential expression in normal tissues from HIPED for C6orf118 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (66.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C6orf118 Gene



SOURCE GeneReport for Unigene cluster for C6orf118 Gene Hs.144734

genes like me logo Genes that share expression patterns with C6orf118: view

Protein tissue co-expression partners for C6orf118 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C6orf118 Gene

Orthologs for C6orf118 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C6orf118 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C9H6orf118 35
  • 73.29 (n)
  • 63.74 (a)
MGC134132 36
  • 57 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C1H6orf118 35
  • 75.1 (n)
  • 69.69 (a)
C6orf118 36
  • 62 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700010I14Rik 35
  • 68.39 (n)
  • 59.62 (a)
1700010I14Rik 16
1700010I14Rik 36
  • 51 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C6H6orf118 35
  • 98.1 (n)
  • 97.14 (a)
C6orf118 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia MGC94891 35
  • 69.52 (n)
  • 62.12 (a)
oppossum
(Monodelphis domestica)
Mammalia C6orf118 36
  • 44 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 38 (a)
OneToMany
-- 36
  • 39 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia C6orf118 36
  • 35 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c6orf118 35
  • 48.34 (n)
  • 32.59 (a)
Species with no ortholog for C6orf118:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C6orf118 Gene

ENSEMBL:
Gene Tree for C6orf118 (if available)
TreeFam:
Gene Tree for C6orf118 (if available)

Paralogs for C6orf118 Gene

No data available for Paralogs for C6orf118 Gene

Variants for C6orf118 Gene

Sequence variations from dbSNP and Humsavar for C6orf118 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs510579 - 165,300,472(+) GTGCA(A/C)ATTTT nc-transcript-variant, reference, missense
rs9459350 - 165,293,446(+) TGCCA(C/G)CTCCA nc-transcript-variant, reference, missense
rs36007498 - 165,301,825(-) TGGAC(A/C/G/T)GGGCC nc-transcript-variant, reference, missense
rs17852379 - 165,300,428(+) CTTTT(C/T)CAAAG nc-transcript-variant, reference, missense
rs540751 - 165,299,477(-) GGCAA(C/T)GCTCC intron-variant, nc-transcript-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for C6orf118 Gene

Variant ID Type Subtype PubMed ID
dgv7033n71 CNV Gain 21882294
nsv5586 CNV Loss 18451855
nsv508438 CNV Loss 20534489
nsv886928 CNV Gain 21882294

Variation tolerance for C6orf118 Gene

Residual Variation Intolerance Score: 95.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.50; 77.63% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C6orf118 Gene

HapMap Linkage Disequilibrium report
C6orf118

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf118 Gene

Disorders for C6orf118 Gene

Relevant External Links for C6orf118

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C6orf118

No disorders were found for C6orf118 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C6orf118 Gene

Publications for C6orf118 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Genome-wide interaction studies reveal sex-specific asthma risk alleles. (PMID: 24824216) Myers R.A. … Nicolae D.L. (Hum. Mol. Genet. 2014) 3
  3. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PMID: 22589738) Fox C.S. … Borecki I.B. (PLoS Genet. 2012) 3
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  5. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3

Products for C6orf118 Gene

Sources for C6orf118 Gene

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