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Aliases for C6orf1 Gene

Aliases for C6orf1 Gene

  • Chromosome 6 Open Reading Frame 1 2 3 5
  • LBH 3 4
  • Protein LBH 4

External Ids for C6orf1 Gene

Previous GeneCards Identifiers for C6orf1 Gene

  • GC06U990175
  • GC06M034323
  • GC06M034214
  • GC06M033936
  • GC06M034540
  • GC06M035560

Summaries for C6orf1 Gene

GeneCards Summary for C6orf1 Gene

C6orf1 (Chromosome 6 Open Reading Frame 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf1 Gene

Genomics for C6orf1 Gene

Regulatory Elements for C6orf1 Gene

Enhancers for C6orf1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C6orf1 on UCSC Golden Path with GeneCards custom track

Promoters for C6orf1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C6orf1 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the C6orf1 gene promoter:

Genomic Location for C6orf1 Gene

34,246,380 bp from pter
34,249,470 bp from pter
3,091 bases
Minus strand

Genomic View for C6orf1 Gene

Genes around C6orf1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C6orf1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C6orf1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C6orf1 Gene

Proteins for C6orf1 Gene

  • Protein details for C6orf1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C6orf1
    Protein Accession:
    Secondary Accessions:
    • A8K299

    Protein attributes for C6orf1 Gene

    159 amino acids
    Molecular mass:
    17113 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C6orf1 Gene

Proteomics data for C6orf1 Gene at MOPED

Post-translational modifications for C6orf1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for C6orf1 Gene

Domains & Families for C6orf1 Gene

Protein Domains for C6orf1 Gene


Suggested Antigen Peptide Sequences for C6orf1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C6orf1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C6orf1 Gene

Function for C6orf1 Gene

Molecular function for C6orf1 Gene

GENATLAS Biochemistry:
chromosome 6 open reading frame 1,located 3of HMGIY,in opposite orientation
genes like me logo Genes that share phenotypes with C6orf1: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C6orf1 Gene

Localization for C6orf1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C6orf1 Gene


Subcellular locations from

Jensen Localization Image for C6orf1 Gene COMPARTMENTS Subcellular localization image for C6orf1 gene
Compartment Confidence
extracellular 4
mitochondrion 2
cytosol 1
nucleus 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for C6orf1 Gene

Pathways & Interactions for C6orf1 Gene

SuperPathways for C6orf1 Gene

No Data Available

Interacting Proteins for C6orf1 Gene

Gene Ontology (GO) - Biological Process for C6orf1 Gene


No data available for Pathways by source and SIGNOR curated interactions for C6orf1 Gene

Drugs & Compounds for C6orf1 Gene

No Compound Related Data Available

Transcripts for C6orf1 Gene

Unigene Clusters for C6orf1 Gene

Chromosome 6 open reading frame 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C6orf1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d
SP1: - -
SP2: - - -
SP3: - -
SP4: -
SP5: - - -
SP6: - -
SP7: -

Relevant External Links for C6orf1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C6orf1 Gene

mRNA expression in normal human tissues for C6orf1 Gene

SOURCE GeneReport for Unigene cluster for C6orf1 Gene Hs.381300

mRNA Expression by UniProt/SwissProt for C6orf1 Gene

Tissue specificity: Expressed in spleen, thymus, prostate, testis, uterus, small intestine, colon and peripheral blood leukocytes.
genes like me logo Genes that share expression patterns with C6orf1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for C6orf1 Gene

Orthologs for C6orf1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C6orf1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C6H6orf1 35
  • 99.78 (n)
  • 99.35 (a)
C6orf1 36
  • 99 (a)
(Danio rerio)
Actinopterygii Dr.3972 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.7226 35
Species with no ortholog for C6orf1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C6orf1 Gene

Gene Tree for C6orf1 (if available)
Gene Tree for C6orf1 (if available)

Paralogs for C6orf1 Gene

(1) SIMAP similar genes for C6orf1 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with C6orf1: view

No data available for Paralogs for C6orf1 Gene

Variants for C6orf1 Gene

Sequence variations from dbSNP and Humsavar for C6orf1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
VAR_056792 -
VAR_060383 -
rs1150776 -- 34,250,101(+) ACAGC(G/T)GCCCC upstream-variant-2KB
rs1150779 -- 34,248,142(-) GACTT(A/G)TAAAT intron-variant
rs10080749 -- 34,250,388(+) CACTG(A/G)ACAAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C6orf1 Gene

Variant ID Type Subtype PubMed ID
nsv885781 CNV Loss 21882294
nsv885784 CNV Loss 21882294

Variation tolerance for C6orf1 Gene

Residual Variation Intolerance Score: 71.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.18; 39.51% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C6orf1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf1 Gene

Disorders for C6orf1 Gene

Relevant External Links for C6orf1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C6orf1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C6orf1 Gene

Publications for C6orf1 Gene

  1. Assignment of a new gene (LBH). (PMID: 10036196) Kazmierczak B. … Bullerdiek J. (Genomics 1999) 2 3 4 67
  2. Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. (PMID: 24324551) Deng X. … Seielstad M. (PLoS ONE 2013) 3
  3. Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. (PMID: 21998595) N'Diaye A. … Haiman C.A. (PLoS Genet. 2011) 3
  4. Identification of 15 loci influencing height in a Korean population. (PMID: 19893584) Kim J.J. … Lee J.K. (J. Hum. Genet. 2010) 3
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3

Products for C6orf1 Gene

Sources for C6orf1 Gene