Aliases for C5orf64 Gene
External Ids for C5orf64 Gene
- HGNC: 26744
- Entrez Gene: 285668
- Ensembl: ENSG00000178722
- UniProtKB: Q2M2E5
Previous GeneCards Identifiers for C5orf64 Gene
- GC05P060933
Summaries for C5orf64 Gene
GeneCards Summary for C5orf64 Gene
C5orf64 (Chromosome 5 Open Reading Frame 64) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C5orf64 Gene
Genomics for C5orf64 Gene
Regulatory Elements for C5orf64 Gene
Enhancers for C5orf64 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH05G061665 | 1 | Ensembl dbSUPER | 6.7 | +28.5 | 28493 | 0.8 | PKNOX1 CEBPG RAD21 IRF9 ZFHX2 ZNF316 NFE2 TRIM24 EGR2 HLF | C5orf64 RNU6-913P GC05M061665 LOC101928651 |
| GH05G061672 | 1 | Ensembl ENCODE dbSUPER | 6.3 | +35.5 | 35456 | 1.1 | GATA2 FOS NR2F2 | C5orf64 RNU6-913P GC05M061665 LOC101928651 |
| GH05G061649 | 1.1 | dbSUPER | 5.2 | +12.4 | 12387 | 1.5 | HDGF PKNOX1 CREB3L1 ARID4B SIN3A ZNF2 YY1 ZNF766 SP3 SP5 | LOC101928651 SMIM15 SMIM15-AS1 C5orf64 HSPD1P22 |
| GH05G061648 | 1.1 | dbSUPER | 5.2 | +12.4 | 12366 | 2.2 | HDGF PKNOX1 CREB3L1 ARID4B SIN3A ZNF2 YY1 ZNF766 SP3 SP5 | LOC101928651 SMIM15 SMIM15-AS1 C5orf64 HSPD1P22 |
| GH05G061651 | 1.1 | dbSUPER | 5.2 | +12.3 | 12272 | 2.2 | HDGF PKNOX1 CREB3L1 ARID4B SIN3A ZNF2 YY1 ZNF766 SP3 SP5 | LOC101928651 SMIM15-AS1 SMIM15 C5orf64 HSPD1P22 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around C5orf64 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for C5orf64 Gene
- Chromosome:
- 5
- Start:
- 61,637,708 bp from pter
- End:
- 61,751,763 bp from pter
- Size:
- 114,056 bases
- Orientation:
- Plus strand
Genomic View for C5orf64 Gene
Genes around C5orf64 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q12.1 by Ensembl
- 5q12.1 by Entrez Gene
- 5q12.1 by HGNC
C5orf64 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C5orf64 Gene
Proteins for C5orf64 Gene
-
Protein details for C5orf64 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q2M2E5-CE064_HUMAN
- Recommended name:
- Uncharacterized protein C5orf64
- Protein Accession:
- Q2M2E5
- Q2M2H1
- Q8N1U8
Protein attributes for C5orf64 Gene
- Size:
- 130 amino acids
- Molecular mass:
- 14817 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for C5orf64 Gene
Other Protein References for C5orf64 Gene
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for C5orf64
-
Abcam antibodies for C5orf64
- Invitrogen Antibodies for C5orf64
- GeneTex C5orf64 antibody for C5orf64
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for C5orf64
- Origene Custom Protein Services for C5orf64
- Search GeneTex for Proteins for C5orf64
Assay Products
No data available for DME Specific Peptides for C5orf64 Gene
Domains & Families for C5orf64 Gene
Protein Domains for C5orf64 Gene
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C5orf64 Gene
Function for C5orf64 Gene
Phenotypes for C5orf64 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for C5orf64
-
-
ViGene Biosciences lentiviral particle packaged cDNA for C5orf64 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for C5orf64 gene
- Search ViGene Biosciences for C5orf64
CRISPR Products
-
OriGene CRISPR knockouts for C5orf64
-
Santa Cruz Biotechnology (SCBT) CRISPR for C5orf64
- GenScript: Design CRISPR guide RNA sequences for C5orf64
miRNA for C5orf64 Gene
- miRTarBase miRNAs that target C5orf64
-
- hsa-mir-4666b (MIRT526308)
- hsa-mir-6826-3p (MIRT526309)
- hsa-mir-505-3p (MIRT526310)
- hsa-mir-7978 (MIRT526311)
- hsa-mir-4456 (MIRT526312)
- hsa-mir-548q (MIRT526313)
- hsa-mir-4299 (MIRT526314)
- hsa-mir-6795-3p (MIRT526315)
- hsa-mir-6887-3p (MIRT526316)
- hsa-mir-6729-3p (MIRT526317)
- hsa-mir-384 (MIRT659967)
- hsa-mir-3124-3p (MIRT659968)
- hsa-mir-587 (MIRT659969)
miRNA Products
- Search ViGene Biosciences for C5orf64
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C5orf64
- Browse OriGene Inhibitory RNA Products For C5orf64
-
ViGene Biosciences ready-to-package AAV shRNAs for C5orf64 gene
Clone Products
-
OriGene ORF clones in human for C5orf64
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C5orf64
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C5orf64
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for C5orf64
-
ViGene Biosciences adenoviral particle packaged cDNA for C5orf64 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for C5orf64 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for C5orf64 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C5orf64 Gene
Localization for C5orf64 Gene
Subcellular locations from UniProtKB/Swiss-Prot for C5orf64 Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 4 |
| mitochondrion | 3 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
Pathways & Interactions for C5orf64 Gene
No data available for Pathways by source and SIGNOR curated interactions for C5orf64 Gene
Transcripts for C5orf64 Gene
mRNA/cDNA for C5orf64 Gene
- (6) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (2) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for C5orf64 Gene
CRISPR Products
-
OriGene CRISPR knockouts for C5orf64
-
Santa Cruz Biotechnology (SCBT) CRISPR for C5orf64
- GenScript: Design CRISPR guide RNA sequences for C5orf64
miRNA Products
- Search ViGene Biosciences for C5orf64
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C5orf64
- Browse OriGene Inhibitory RNA Products For C5orf64
-
ViGene Biosciences ready-to-package AAV shRNAs for C5orf64 gene
Clone Products
-
OriGene ORF clones in human for C5orf64
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C5orf64
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C5orf64
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for C5orf64 Gene
mRNA differential expression in normal tissues according to GTEx for C5orf64 Gene
This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x9.7), Brain - Substantia nigra (x7.5), Brain - Hippocampus (x4.6), Brain - Putamen (basal ganglia) (x4.5), Brain - Hypothalamus (x4.5), and Brain - Amygdala (x4.3).
NURSA nuclear receptor signaling pathways regulating expression of C5orf64 Gene:
C5orf64SOURCE GeneReport for Unigene cluster for C5orf64 Gene:
Hs.683866Evidence on tissue expression from TISSUES for C5orf64 Gene
- Nervous system(4.2)
Primer Products
-
OriGene qPCR primer pairs for C5orf64
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C5orf64 Gene
Orthologs for C5orf64 Gene
This gene was present in the common ancestor of human and chimp.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C5H5orf64 34 |
|
||
| C5orf64 35 |
|
OneToOne |
- Species where no ortholog for C5orf64 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for C5orf64 Gene
No data available for Paralogs for C5orf64 Gene
Variants for C5orf64 Gene
| SNP ID | Clin | Chr 05 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000037993 | -- | 61,645,080(+) | AGGAG(A/C)CTTAC | intron-variant | |
| rs1000061363 | -- | 61,669,793(+) | AAGTT(C/T)CATTC | intron-variant | |
| rs1000067314 | -- | 61,708,540(+) | CAAGG(C/T)AACTG | intron-variant | |
| rs1000068335 | -- | 61,665,316(+) | CACAC(A/G)AGAGC | intron-variant | |
| rs1000106470 | -- | 61,690,107(+) | CTTTA(C/T)GAGGA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2671982 | CNV | deletion | 23128226 |
| esv2730246 | CNV | deletion | 23290073 |
| esv2730247 | CNV | deletion | 23290073 |
| esv3605219 | CNV | loss | 21293372 |
| esv3605221 | CNV | gain | 21293372 |
| esv3894197 | CNV | loss | 25118596 |
Residual Variation Intolerance Score:
87.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
13.68;
95.71% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for C5orf64 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C5orf64
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C5orf64 Gene
Disorders for C5orf64 Gene
Relevant External Links for C5orf64
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- C5orf64
No disorders were found for C5orf64 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C5orf64 Gene
Publications for C5orf64 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
- Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint. (PMID: 26354767) Bailey M.L. … Hieter P. (Genetics 2015) 3 64
- Genome-wide association study of Alzheimer's disease. (PMID: 22832961) Kamboh M.I. … Barmada M.M. (Transl Psychiatry 2012) 3 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
Products for C5orf64 Gene
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- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
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- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for C5orf64
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- OriGene qPCR primer pairs for C5orf64
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- OriGene ORF clones in human for C5orf64
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for C5orf64 in any vector
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- GenScript: Design CRISPR guide RNA sequences for C5orf64
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- Novus Biologicals Antibodies for C5orf64
- Novus Biologicals
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- ViGene Biosciences adenoviral particle packaged cDNA for C5orf64 gene
- ViGene Biosciences lentiviral particle packaged cDNA for C5orf64 gene
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- Search ViGene Biosciences for C5orf64
- Horizon Cell Lines for C5orf64
- Cyagen custom Knockout/knockin (KOKI) mouse models for C5orf64
- VectorBuilder custom plasmid, inducible vectors for C5orf64
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C5orf64
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for C5orf64 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer