Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C5orf63 Gene

Aliases for C5orf63 Gene

  • Chromosome 5 Open Reading Frame 63 2 3 5
  • Glutaredoxin-Like Protein YDR286C Homolog 3
  • YDR286C 3

External Ids for C5orf63 Gene

Previous GeneCards Identifiers for C5orf63 Gene

  • GC05M126379

Summaries for C5orf63 Gene

GeneCards Summary for C5orf63 Gene

C5orf63 (Chromosome 5 Open Reading Frame 63) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C5orf63 Gene

Genomics for C5orf63 Gene

Regulatory Elements for C5orf63 Gene

Enhancers for C5orf63 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C5orf63 on UCSC Golden Path with GeneCards custom track

Promoters for C5orf63 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C5orf63 on UCSC Golden Path with GeneCards custom track

Genomic Location for C5orf63 Gene

127,035,666 bp from pter
127,073,539 bp from pter
37,874 bases
Minus strand

Genomic View for C5orf63 Gene

Genes around C5orf63 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C5orf63 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C5orf63 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C5orf63 Gene

Proteins for C5orf63 Gene

  • Protein details for C5orf63 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Glutaredoxin-like protein C5orf63
    Protein Accession:
    Secondary Accessions:
    • G3V557

    Protein attributes for C5orf63 Gene

    138 amino acids
    Molecular mass:
    15764 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C5orf63 Gene


neXtProt entry for C5orf63 Gene

Proteomics data for C5orf63 Gene at MOPED

Post-translational modifications for C5orf63 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C5orf63 Gene

Domains & Families for C5orf63 Gene

Protein Domains for C5orf63 Gene

Suggested Antigen Peptide Sequences for C5orf63 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the glutaredoxin family. YDR286C subfamily.
  • Belongs to the glutaredoxin family. YDR286C subfamily.
genes like me logo Genes that share domains with C5orf63: view

No data available for Gene Families for C5orf63 Gene

Function for C5orf63 Gene

Phenotypes for C5orf63 Gene

genes like me logo Genes that share phenotypes with C5orf63: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C5orf63 Gene

Localization for C5orf63 Gene

Subcellular locations from

Jensen Localization Image for C5orf63 Gene COMPARTMENTS Subcellular localization image for C5orf63 gene
Compartment Confidence
mitochondrion 5
extracellular 2
cytosol 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C5orf63 Gene

Pathways & Interactions for C5orf63 Gene

SuperPathways for C5orf63 Gene

No Data Available

Interacting Proteins for C5orf63 Gene

Gene Ontology (GO) - Biological Process for C5orf63 Gene


No data available for Pathways by source and SIGNOR curated interactions for C5orf63 Gene

Drugs & Compounds for C5orf63 Gene

No Compound Related Data Available

Transcripts for C5orf63 Gene

Unigene Clusters for C5orf63 Gene

Chromosome 5 open reading frame 63:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C5orf63 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5
SP1: - -
SP3: - - - -
SP4: -

Relevant External Links for C5orf63 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C5orf63 Gene

mRNA expression in normal human tissues for C5orf63 Gene

Protein differential expression in normal tissues from HIPED for C5orf63 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C5orf63 Gene

SOURCE GeneReport for Unigene cluster for C5orf63 Gene Hs.49573

genes like me logo Genes that share expression patterns with C5orf63: view

Protein tissue co-expression partners for C5orf63 Gene

- Elite partner

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C5orf63 Gene

Orthologs for C5orf63 Gene

This gene was present in the common ancestor of animals.

Orthologs for C5orf63 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C7H5orf63 35
  • 89.57 (n)
  • 86.96 (a)
C5orf63 36
  • 48 (a)
(Canis familiaris)
Mammalia C11H5orf63 35
  • 89.77 (n)
  • 85.09 (a)
C5orf63 36
  • 46 (a)
(Mus musculus)
Mammalia C330018D20Rik 35
  • 88.18 (n)
  • 86.36 (a)
C330018D20Rik 16
C330018D20Rik 36
  • 43 (a)
(Pan troglodytes)
Mammalia C5H5orf63 35
  • 100 (n)
  • 100 (a)
(Rattus norvegicus)
Mammalia LOC100174910 35
  • 89.39 (n)
  • 89.09 (a)
(Monodelphis domestica)
Mammalia C5orf63 36
  • 35 (a)
(Gallus gallus)
Aves CZH5ORF63 35
  • 66.67 (n)
  • 64.29 (a)
C5orf63 36
  • 30 (a)
(Anolis carolinensis)
Reptilia C5orf63 36
  • 32 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101733920 35
  • 63.43 (n)
  • 63.11 (a)
(Danio rerio)
Actinopterygii im:7154516 35
  • 70.88 (n)
  • 73.56 (a)
C10H5orf63 36
  • 34 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG9147 36
  • 6 (a)
Species with no ortholog for C5orf63:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C5orf63 Gene

Gene Tree for C5orf63 (if available)
Gene Tree for C5orf63 (if available)

Paralogs for C5orf63 Gene Pseudogenes for C5orf63 Gene

genes like me logo Genes that share paralogs with C5orf63: view

No data available for Paralogs for C5orf63 Gene

Variants for C5orf63 Gene

Sequence variations from dbSNP and Humsavar for C5orf63 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1004392 -- 127,052,302(+) AACAC(A/G)TCAGT intron-variant
rs6595747 -- 127,046,829(+) GGCAT(A/G)AGCAG intron-variant, nc-transcript-variant, utr-variant-3-prime
rs6595748 -- 127,068,523(+) AAAAA(C/T)AATGA intron-variant
rs3048711 -- 127,039,835(+) ATAGA(-/TAGA)GCTGT intron-variant, nc-transcript-variant
rs6860157 -- 127,059,192(+) CCGAA(C/G/T)GAAAC intron-variant

Variation tolerance for C5orf63 Gene

Gene Damage Index Score: 1.25; 25.07% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for C5orf63 Gene

Disorders for C5orf63 Gene

Relevant External Links for C5orf63

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C5orf63 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C5orf63 Gene

Publications for C5orf63 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 67

Products for C5orf63 Gene

Sources for C5orf63 Gene