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Aliases for C5orf60 Gene

Aliases for C5orf60 Gene

  • Chromosome 5 Open Reading Frame 60 2 3

External Ids for C5orf60 Gene

Previous GeneCards Identifiers for C5orf60 Gene

  • GC05M179003
  • GC05M179071
  • GC05P173801

Summaries for C5orf60 Gene

GeneCards Summary for C5orf60 Gene

C5orf60 (Chromosome 5 Open Reading Frame 60) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C5orf60 Gene

Genomics for C5orf60 Gene

Genomic Location for C5orf60 Gene

Start:
179,641,544 bp from pter
End:
179,645,082 bp from pter
Size:
3,539 bases
Orientation:
Minus strand

Genomic View for C5orf60 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C5orf60 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C5orf60 Gene

No data available for Regulatory Elements for C5orf60 Gene

Proteins for C5orf60 Gene

  • Protein details for C5orf60 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NFR6-CE060_HUMAN
    Recommended name:
    Putative uncharacterized protein C5orf60
    Protein Accession:
    A6NFR6
    Secondary Accessions:
    • A1L488
    • B7ZM52
    • B7ZM53

    Protein attributes for C5orf60 Gene

    Size:
    353 amino acids
    Molecular mass:
    39250 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI30443.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAI30445.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for C5orf60 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C5orf60 Gene

Proteomics data for C5orf60 Gene at MOPED

Post-translational modifications for C5orf60 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C5orf60 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C5orf60 Gene

Domains for C5orf60 Gene

Protein Domains for C5orf60 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C5orf60: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C5orf60 Gene

Function for C5orf60 Gene

Gene Ontology (GO) - Molecular Function for C5orf60 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C5orf60: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C5orf60

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C5orf60 Gene

Localization for C5orf60 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C5orf60 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C5orf60 Gene COMPARTMENTS Subcellular localization image for C5orf60 gene
Compartment Confidence
golgi apparatus 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for C5orf60 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C5orf60: view

Pathways for C5orf60 Gene

SuperPathways for C5orf60 Gene

No Data Available

Interacting Proteins for C5orf60 Gene

Gene Ontology (GO) - Biological Process for C5orf60 Gene

None

No data available for Pathways by source for C5orf60 Gene

Transcripts for C5orf60 Gene

mRNA/cDNA for C5orf60 Gene

(5) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(6) REFSEQ mRNAs :
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C5orf60 Gene

Chromosome 5 open reading frame 60:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C5orf60

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for C5orf60

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C5orf60 Gene

No ASD Table

Relevant External Links for C5orf60 Gene

GeneLoc Exon Structure for
C5orf60
ECgene alternative splicing isoforms for
C5orf60

Expression for C5orf60 Gene

mRNA expression in normal human tissues for C5orf60 Gene

mRNA differential expression in normal tissues according to GTEx for C5orf60 Gene

This gene is overexpressed in Testis (50.2).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C5orf60 Gene

SOURCE GeneReport for Unigene cluster for C5orf60 Gene Hs.558748

genes like me logo Genes that share expressions with C5orf60: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C5orf60 Gene

Orthologs for C5orf60 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C5orf60 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 55 (a)
OneToMany
LOC462326 35
  • 97.51 (n)
  • 95.18 (a)
Species with no ortholog for C5orf60:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C5orf60 Gene

ENSEMBL:
Gene Tree for C5orf60 (if available)
TreeFam:
Gene Tree for C5orf60 (if available)

Paralogs for C5orf60 Gene

Pseudogenes.org Pseudogenes for C5orf60 Gene

genes like me logo Genes that share paralogs with C5orf60: view

No data available for Paralogs for C5orf60 Gene

Variants for C5orf60 Gene

Sequence variations from dbSNP and Humsavar for C5orf60 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs1319931 - 179,644,858(+) GGGGC(A/G)TAAGA reference, missense, nc-transcript-variant
rs2411400 -- 179,644,723(-) CATCA(A/G)CCAGA intron-variant
rs3987734 -- 179,644,814(-) CCAGA(-/GAG)GAGGA cds-indel
rs4557391 -- 179,645,039(-) CCCCA(A/G)TAACT utr-variant-5-prime, nc-transcript-variant
rs4645306 -- 179,644,946(-) GTTAT(C/T)GGTAC synonymous-codon, reference, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for C5orf60 Gene

Variant ID Type Subtype PubMed ID
nsv883270 CNV Loss 21882294
nsv7375 OTHER Inversion 18451855
nsv281 OTHER Inversion 15895083
nsv830560 CNV Loss 17160897
nsv883273 CNV Loss 21882294
esv1005618 OTHER Inversion 20482838
nsv499095 OTHER Inversion 21111241
esv1419350 OTHER Inversion 17803354
nsv823358 CNV Loss 20364138

Relevant External Links for C5orf60 Gene

HapMap Linkage Disequilibrium report
C5orf60

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C5orf60 Gene

Disorders for C5orf60 Gene

No disorders were found for C5orf60 Gene.

No data available for UniProtKB/Swiss-Prot for C5orf60 Gene

Publications for C5orf60 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for C5orf60 Gene

Sources for C5orf60 Gene

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