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Aliases for C5orf51 Gene

Aliases for C5orf51 Gene

  • Chromosome 5 Open Reading Frame 51 2 3

External Ids for C5orf51 Gene

Previous GeneCards Identifiers for C5orf51 Gene

  • GC05P041940
  • GC05P041857
  • GC05P041905
  • GC05P041906
  • GC05P041907
  • GC05P041908
  • GC05P041909
  • GC05P041910
  • GC05P041911

Summaries for C5orf51 Gene

GeneCards Summary for C5orf51 Gene

C5orf51 (Chromosome 5 Open Reading Frame 51) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C5orf51 Gene

Genomics for C5orf51 Gene

Regulatory Elements for C5orf51 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C5orf51 Gene

41,904,188 bp from pter
41,921,636 bp from pter
17,449 bases
Plus strand

Genomic View for C5orf51 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C5orf51 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C5orf51 Gene

Proteins for C5orf51 Gene

  • Protein details for C5orf51 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UPF0600 protein C5orf51
    Protein Accession:
    Secondary Accessions:
    • A2RRM9

    Protein attributes for C5orf51 Gene

    294 amino acids
    Molecular mass:
    33620 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAI31722.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Aberrant splice sites.; Evidence={ECO:0000305};

neXtProt entry for C5orf51 Gene

Proteomics data for C5orf51 Gene at MOPED

Post-translational modifications for C5orf51 Gene

  • Ubiquitination at Lys97
  • Modification sites at PhosphoSitePlus

Other Protein References for C5orf51 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C5orf51 Gene

Domains for C5orf51 Gene

Protein Domains for C5orf51 Gene


Suggested Antigen Peptide Sequences for C5orf51 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • A6NDU8
  • Belongs to the UPF0600 family.
genes like me logo Genes that share domains with C5orf51: view

No data available for Gene Families for C5orf51 Gene

Function for C5orf51 Gene

Phenotypes for C5orf51 Gene

GenomeRNAi human phenotypes for C5orf51:
genes like me logo Genes that share phenotypes with C5orf51: view

Animal Model Products

CRISPR Products

miRNA for C5orf51 Gene

miRTarBase miRNAs that target C5orf51

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C5orf51

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for C5orf51 Gene

Localization for C5orf51 Gene

Subcellular locations from

Jensen Localization Image for C5orf51 Gene COMPARTMENTS Subcellular localization image for C5orf51 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C5orf51 Gene

Pathways for C5orf51 Gene

SuperPathways for C5orf51 Gene

No Data Available

Interacting Proteins for C5orf51 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000371061 A6NDU8-CE051_HUMAN for C5orf51 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for C5orf51 Gene


No data available for Pathways by source for C5orf51 Gene

Transcripts for C5orf51 Gene

mRNA/cDNA for C5orf51 Gene

Unigene Clusters for C5orf51 Gene

Chromosome 5 open reading frame 51:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C5orf51

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C5orf51 Gene

No ASD Table

Relevant External Links for C5orf51 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C5orf51 Gene

mRNA expression in normal human tissues for C5orf51 Gene

Protein differential expression in normal tissues for C5orf51 Gene

This gene is overexpressed in Bone (45.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C5orf51 Gene

SOURCE GeneReport for Unigene cluster for C5orf51 Gene Hs.29899

genes like me logo Genes that share expressions with C5orf51: view

Expression partners for C5orf51 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C5orf51 Gene

Orthologs for C5orf51 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C5orf51 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C20H5orf51 35
  • 90.33 (n)
  • 91.13 (a)
C5orf51 36
  • 90 (a)
(Canis familiaris)
Mammalia C4H5orf51 35
  • 91.92 (n)
  • 92.83 (a)
C5orf51 36
  • 93 (a)
(Mus musculus)
Mammalia AW549877 35
  • 86.05 (n)
  • 88.78 (a)
AW549877 16
AW549877 36
  • 89 (a)
(Pan troglodytes)
Mammalia C5H5orf51 35
  • 99.43 (n)
  • 99.66 (a)
C5orf51 36
  • 100 (a)
(Monodelphis domestica)
Mammalia C5orf51 36
  • 65 (a)
(Ornithorhynchus anatinus)
Mammalia C5orf51 36
  • 66 (a)
(Gallus gallus)
Aves CZH5ORF51 35
  • 64.91 (n)
  • 54.93 (a)
(Anolis carolinensis)
Reptilia C5orf51 36
  • 52 (a)
(Danio rerio)
Actinopterygii si:dkey-46a10.3 35
  • 55.96 (n)
  • 50 (a)
C8H5orf51 36
  • 46 (a)
Species with no ortholog for C5orf51:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C5orf51 Gene

Gene Tree for C5orf51 (if available)
Gene Tree for C5orf51 (if available)

Paralogs for C5orf51 Gene

No data available for Paralogs for C5orf51 Gene

Variants for C5orf51 Gene

Sequence variations from dbSNP and Humsavar for C5orf51 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs166743 -- 41,907,926(-) CTGAT(G/T)TCATT intron-variant
rs277410 -- 41,907,526(-) TTTTT(C/T)CTACA intron-variant
rs277411 -- 41,902,609(-) TCAGG(C/T)TTTTA upstream-variant-2KB
rs277412 -- 41,913,737(-) TTTTC(C/T)ATGAA intron-variant
rs614007 -- 41,914,588(-) gagat(G/T)atgtc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C5orf51 Gene

Variant ID Type Subtype PubMed ID
nsv830272 CNV Gain 17160897
nsv830273 CNV Gain 17160897
nsv327668 CNV Loss 16902084

Relevant External Links for C5orf51 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C5orf51 Gene

Disorders for C5orf51 Gene

No disorders were found for C5orf51 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for C5orf51 Gene

Publications for C5orf51 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3
  2. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for C5orf51 Gene

Sources for C5orf51 Gene

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