C5orf51 Gene
protein-coding GIFtS: 39
GCID: GC05P041909
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chromosome 5 open reading frame 51
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Aliases
for C5orf51 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 5 Open Reading Frame 511 2 | | LOC2856361 | | UPF0600 Protein C5orf512 |
Export aliases for C5orf51 gene to outside databasesPrevious GC identifers: GC05P041940 GC05P041857 GC05P041905 GC05P041906 GC05P041907 GC05P041908 |
Summaries
for C5orf51 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C5orf51 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_006576.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C5orf51 gene promoter:
MEF-2A USF1 AML1a USF-1 Hand1 aMEF-2 GATA-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for C5orf51
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C5orf51 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5p13.1 Ensembl cytogenetic band: 5p13.1 HGNC cytogenetic band: 5p13.1C5orf51 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P041909: view genomic region
(about GC identifiers)
Start:
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41,904,290 bp from pter |
End:
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41,921,738 bp from pter |
Size:
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17,449 bases |
Orientation:
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plus strand |
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Proteins
for C5orf51 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CE051_HUMAN, A6NDU8 (See
protein sequence)Recommended Name: UPF0600 protein C5orf51 Size: 294 amino acids; 33620 Da
Sequence caution: Sequence=AAI31722.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Aberrant splice sites;
Secondary accessions: A2RRM9Explore the universe of human proteins at neXtProt for C5orf51: NX_A6NDU8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A6NDU8
C5orf51 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_787117.3
ENSEMBL proteins: ENSP00000371061
Human Recombinant Protein Products:
C5orf51 Antibody Products:
Assay Products for C5orf51: |
Protein
Domains /
Families
for C5orf51 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: A6NDU8 UniProtKB/Swiss-Prot: CE051_HUMAN, A6NDU8Similarity: Belongs to the UPF0600 family |
Function
for C5orf51 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C5orf51 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C5orf51 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C5orf51 (NM_175921) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C5orf51 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C5orf51 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C5orf51 |
1 GenomeRNAi human phenotype for C5orf51:
|
Pathways & Interactions
for C5orf51 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C5orf51
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
3 Interacting proteins for C5orf51 (A6NDU83 ENSP000003710614) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for C5orf51 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C5orf51
Search CenterWatch for drugs/clinical trials and news about C5orf51 / CE051
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Transcripts
for C5orf51 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C5orf51 gene: NM_175921.4 Unigene Cluster for C5orf51: Chromosome 5 open reading frame 51 Hs.29899 [show with all ESTs]Unigene Representative Sequence: NM_1759213 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000505931 ENST00000381647(uc003jmo.3) ENST00000509976
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C5orf51 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C5orf51 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C5orf51 (NM_175921) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C5orf51 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C5orf51 |
Additional cDNA sequence: AK094002.1 AL833916.1 BC131721.1 4 DOTS entries: DT.70102807 DT.315582 DT.100888333 DT.40207983 24/80 AceView cDNA sequences (see all 80): R79786 AI358353 AL046640 BX103366 AA236186 AX748406 AA417772 AK094002 AA283886 AL833916 AW731692 BQ010827 BU609216 AI093102 AI432988 BU624671 AA417741 AA618522 BE794875 CB106365 AI246459 BU934995 BQ720445 BX508928
GeneLoc Exon Structure
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Expression
for C5orf51 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C5orf51 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTATTTCTTC
About this image
See C5orf51 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C5orf51
SOURCE GeneReport for Unigene cluster: Hs.29899
SABiosciences Custom PCR Arrays for C5orf51
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C5orf51
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C5orf51 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C5orf51 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C5orf51 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C5orf51 |
Orthologs
for C5orf51 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for C5orf51 gene from 4/10 species (see all 10) About this table
ENSEMBL Gene Tree for C5orf51 (if available)
TreeFam Gene Tree for C5orf51 (if available) |
Paralogs
for C5orf51 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C5orf51 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for C5orf51 (41904290 - 41921738 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for C5orf51
2 CNVs: 6396 93004 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C5orf51 |
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Disorders
/ Diseases
for C5orf51 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C5orf51 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C5orf51 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C5orf51) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 3 Ota T.... Sugano S. (2004)
- The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)1, 2 Schmutz J.... Rubin E.M. (2004)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for C5orf51 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing C5orf51 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C5orf51 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C5orf51 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C5orf51 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for C5orf51 gene:
Search GeneIP for patents involving C5orf51
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C5orf51 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C5orf51 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C5orf51 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C5orf51 | | | OriGene Protein Over-expression Lysate for C5orf51 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C5orf51 | | OriGene 3'-UTR Clone for C5orf51 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C5orf51 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C5orf51 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for C5orf51 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C5orf51 | | OriGene Custom Protein Services for C5orf51 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C5orf51 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C5orf51 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C5orf51 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C5orf51 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C5orf51 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C5orf51 |
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 |  |  |  | |
| | | | Search Tocris compounds for C5orf51 |
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 | | | C5orf51 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C5orf51 |
|  |  |  | | | | Search ThermoFisher Antibodies for C5orf51 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C5orf51 |
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