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Aliases for C5orf49 Gene

Aliases for C5orf49 Gene

  • Chromosome 5 Open Reading Frame 49 2 3

External Ids for C5orf49 Gene

Summaries for C5orf49 Gene

GeneCards Summary for C5orf49 Gene

C5orf49 (Chromosome 5 Open Reading Frame 49) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C5orf49 Gene

Genomics for C5orf49 Gene

Regulatory Elements for C5orf49 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C5orf49 Gene

7,830,378 bp from pter
7,851,490 bp from pter
21,113 bases
Minus strand

Genomic View for C5orf49 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C5orf49 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C5orf49 Gene

Proteins for C5orf49 Gene

  • Protein details for C5orf49 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C5orf49
    Protein Accession:

    Protein attributes for C5orf49 Gene

    147 amino acids
    Molecular mass:
    16991 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C5orf49 Gene

Proteomics data for C5orf49 Gene at MOPED

Post-translational modifications for C5orf49 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C5orf49 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C5orf49 Gene

Domains & Families for C5orf49 Gene

Protein Domains for C5orf49 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C5orf49: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C5orf49 Gene

Function for C5orf49 Gene

Phenotypes for C5orf49 Gene

GenomeRNAi human phenotypes for C5orf49:
genes like me logo Genes that share phenotypes with C5orf49: view

Animal Model Products

CRISPR Products

miRNA for C5orf49 Gene

miRTarBase miRNAs that target C5orf49

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C5orf49

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for C5orf49 Gene

Localization for C5orf49 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C5orf49 Gene

Pathways & Interactions for C5orf49 Gene

SuperPathways for C5orf49 Gene

No Data Available

Interacting Proteins for C5orf49 Gene

Gene Ontology (GO) - Biological Process for C5orf49 Gene


No data available for Pathways by source and SIGNOR curated interactions for C5orf49 Gene

Drugs & Compounds for C5orf49 Gene

No Compound Related Data Available

Transcripts for C5orf49 Gene

mRNA/cDNA for C5orf49 Gene

Unigene Clusters for C5orf49 Gene

Chromosome 5 open reading frame 49:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C5orf49

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C5orf49 Gene

No ASD Table

Relevant External Links for C5orf49 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C5orf49 Gene

mRNA expression in normal human tissues for C5orf49 Gene

mRNA differential expression in normal tissues according to GTEx for C5orf49 Gene

This gene is overexpressed in Testis (x8.2) and Brain - Hypothalamus (x4.6).

Protein differential expression in normal tissues from HIPED for C5orf49 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C5orf49 Gene

SOURCE GeneReport for Unigene cluster for C5orf49 Gene Hs.709979

genes like me logo Genes that share expression patterns with C5orf49: view

Protein tissue co-expression partners for C5orf49 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C5orf49 Gene

Orthologs for C5orf49 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C5orf49 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia 1700001L19Rik 35
  • 79.63 (n)
  • 75 (a)
1700001L19Rik 16
1700001L19Rik 36
  • 59 (a)
(Pan troglodytes)
Mammalia C5H5orf49 35
  • 99.09 (n)
  • 98.64 (a)
C5orf49 36
  • 99 (a)
(Rattus norvegicus)
Mammalia RGD1308544 35
  • 80.82 (n)
  • 78.77 (a)
(Canis familiaris)
Mammalia C5orf49 36
  • 69 (a)
(Monodelphis domestica)
Mammalia C5orf49 36
  • 60 (a)
(Ornithorhynchus anatinus)
Mammalia C5orf49 36
  • 58 (a)
(Gallus gallus)
Aves LOC100857376 35
  • 65.32 (n)
  • 59.68 (a)
C5orf49 36
  • 49 (a)
(Anolis carolinensis)
Reptilia C5orf49 36
  • 49 (a)
(Danio rerio)
Actinopterygii si:dkeyp-46h3.1 35
  • 52.34 (n)
  • 48.76 (a)
C19H5orf49 36
  • 40 (a)
Species with no ortholog for C5orf49:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C5orf49 Gene

Gene Tree for C5orf49 (if available)
Gene Tree for C5orf49 (if available)

Paralogs for C5orf49 Gene

No data available for Paralogs for C5orf49 Gene

Variants for C5orf49 Gene

Sequence variations from dbSNP and Humsavar for C5orf49 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
VAR_043546 -
VAR_043547 -
VAR_043548 -

Structural Variations from Database of Genomic Variants (DGV) for C5orf49 Gene

Variant ID Type Subtype PubMed ID
esv2659269 CNV Deletion 23128226
esv26647 CNV Loss 19812545
esv273206 CNV Insertion 20981092
esv272060 CNV Insertion 20981092

Variation tolerance for C5orf49 Gene

Residual Variation Intolerance Score: 89.14% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.94; 87.24% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C5orf49 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C5orf49 Gene

Disorders for C5orf49 Gene

Relevant External Links for C5orf49

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C5orf49: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C5orf49 Gene

Publications for C5orf49 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for C5orf49 Gene

Sources for C5orf49 Gene

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