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Aliases for C5orf47 Gene

Aliases for C5orf47 Gene

  • Chromosome 5 Open Reading Frame 47 2 3 5

External Ids for C5orf47 Gene

Previous GeneCards Identifiers for C5orf47 Gene

  • GC05P173334
  • GC05P168512
  • GC05P173400

Summaries for C5orf47 Gene

GeneCards Summary for C5orf47 Gene

C5orf47 (Chromosome 5 Open Reading Frame 47) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C5orf47 Gene

Genomics for C5orf47 Gene

Regulatory Elements for C5orf47 Gene

Enhancers for C5orf47 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05G173757 2 FANTOM5 Ensembl ENCODE dbSUPER 11.3 -210.6 -210607 10.6 MLX CREB3L1 DMAP1 YY1 SLC30A9 MEF2D GLIS1 RCOR2 NBN NR2C1 C5orf47 BOD1 CPEB4 ATP6V0E1 LINC01484 LINC01485
GH05G173922 1.5 Ensembl ENCODE dbSUPER 12.5 -49.1 -49090 5.0 PKNOX1 FEZF1 ZNF2 ZNF121 KLF7 ZNF263 TSHZ1 REST TBX21 ZNF610 C5orf47 BOD1 HMP19 CPEB4 GC05M173953
GH05G173940 1.4 Ensembl ENCODE dbSUPER 12.1 -29.3 -29298 7.0 FOXA2 ATF1 MLX ARID4B DMAP1 SP5 JUNB PPARG KAT8 MIER3 HMP19 C5orf47 BOD1 ENSG00000253244 LINC01485 GC05M173953 CPEB4
GH05G173622 1.2 ENCODE dbSUPER 12 -349.5 -349535 3.7 HDGF FOXA2 PKNOX1 MLX ARID4B SIN3A GATA2 REST PBX2 RCOR2 C5orf47 ENSG00000253244 HMP19 LOC285593 BOD1 LINC01863
GH05G173917 1.3 ENCODE dbSUPER 10.9 -54.2 -54217 4.8 ATF1 CREB3L1 ARNT SIN3A FOS ZNF263 REST TBX21 ZNF518A SREBF1 BOD1 C5orf47 HMP19 CPEB4 GC05M173953
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C5orf47 on UCSC Golden Path with GeneCards custom track

Promoters for C5orf47 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000191037 -379 801 PKNOX1 ARNT WRNIP1 ARID4B ZNF2 YY1 GATA2 ZNF143 ZHX2 MXD4

Genomic Location for C5orf47 Gene

173,973,779 bp from pter
174,006,140 bp from pter
32,362 bases
Plus strand

Genomic View for C5orf47 Gene

Genes around C5orf47 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C5orf47 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C5orf47 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C5orf47 Gene

Proteins for C5orf47 Gene

  • Protein details for C5orf47 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C5orf47
    Protein Accession:
    Secondary Accessions:
    • Q8IYU7

    Protein attributes for C5orf47 Gene

    176 amino acids
    Molecular mass:
    19206 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH34971.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH92489.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for C5orf47 Gene

Post-translational modifications for C5orf47 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C5orf47 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C5orf47 Gene

Domains & Families for C5orf47 Gene

Protein Domains for C5orf47 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C5orf47: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C5orf47 Gene

Function for C5orf47 Gene

Phenotypes for C5orf47 Gene

GenomeRNAi human phenotypes for C5orf47:
genes like me logo Genes that share phenotypes with C5orf47: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C5orf47 Gene

Localization for C5orf47 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C5orf47 gene
Compartment Confidence
nucleus 2
mitochondrion 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C5orf47 Gene

Pathways & Interactions for C5orf47 Gene

SuperPathways for C5orf47 Gene

No Data Available

Interacting Proteins for C5orf47 Gene

Gene Ontology (GO) - Biological Process for C5orf47 Gene


No data available for Pathways by source and SIGNOR curated interactions for C5orf47 Gene

Transcripts for C5orf47 Gene

mRNA/cDNA for C5orf47 Gene

Unigene Clusters for C5orf47 Gene

Chromosome 5 open reading frame 47:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C5orf47 Gene

No ASD Table

Relevant External Links for C5orf47 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C5orf47 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C5orf47 Gene

mRNA differential expression in normal tissues according to GTEx for C5orf47 Gene

This gene is overexpressed in Testis (x44.2).

Protein differential expression in normal tissues from HIPED for C5orf47 Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C5orf47 Gene

Protein tissue co-expression partners for C5orf47 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C5orf47 Gene:


SOURCE GeneReport for Unigene cluster for C5orf47 Gene:

genes like me logo Genes that share expression patterns with C5orf47: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C5orf47 Gene

Orthologs for C5orf47 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C5orf47 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C5H5orf47 34
  • 98.67 (n)
C5orf47 35
  • 97 (a)
(Canis familiaris)
Mammalia C5orf47 35
  • 82 (a)
(Mus musculus)
Mammalia 4930524B15Rik 34 16 35
  • 66.25 (n)
(Rattus norvegicus)
Mammalia RGD1311343 34
  • 64.95 (n)
Species where no ortholog for C5orf47 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C5orf47 Gene

Gene Tree for C5orf47 (if available)
Gene Tree for C5orf47 (if available)

Paralogs for C5orf47 Gene

No data available for Paralogs for C5orf47 Gene

Variants for C5orf47 Gene

Sequence variations from dbSNP and Humsavar for C5orf47 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1000005521 -- 174,005,059(+) CCTCC(A/G)CCAGT intron-variant, utr-variant-3-prime
rs1000104273 -- 173,988,214(+) CGCAC(C/G)ATTGC upstream-variant-2KB
rs1000316627 -- 173,998,451(+) ATACC(A/G)GTGAA intron-variant
rs1000325513 -- 173,992,228(+) ATTTT(G/T)TTAAT intron-variant
rs1000357360 -- 173,992,928(+) CTTTA(A/G)ATCAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C5orf47 Gene

Variant ID Type Subtype PubMed ID
dgv1667e212 CNV loss 25503493
esv2497414 CNV deletion 19546169
nsv600298 CNV gain 21841781
nsv600323 CNV gain 21841781

Variation tolerance for C5orf47 Gene

Gene Damage Index Score: 3.36; 53.83% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C5orf47 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C5orf47 Gene

Disorders for C5orf47 Gene

Relevant External Links for C5orf47

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C5orf47 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C5orf47 Gene

Publications for C5orf47 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  2. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64

Products for C5orf47 Gene

Sources for C5orf47 Gene

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