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Aliases for C5orf45 Gene

Aliases for C5orf45 Gene

  • Chromosome 5 Open Reading Frame 45 2 3
  • Truncated Calcium Binding Protein 2

External Ids for C5orf45 Gene

Previous GeneCards Identifiers for C5orf45 Gene

  • GC05M179197
  • GC05M179198
  • GC05M179261
  • GC05M173989

Summaries for C5orf45 Gene

GeneCards Summary for C5orf45 Gene

C5orf45 (Chromosome 5 Open Reading Frame 45) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C5orf45 Gene

Genomics for C5orf45 Gene

Regulatory Elements for C5orf45 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C5orf45 Gene

179,835,133 bp from pter
179,862,173 bp from pter
27,041 bases
Minus strand

Genomic View for C5orf45 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C5orf45 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C5orf45 Gene

Proteins for C5orf45 Gene

  • Protein details for C5orf45 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UPF0544 protein C5orf45
    Protein Accession:
    Secondary Accessions:
    • B5MD09
    • E9PAK6
    • Q7Z3D8
    • Q9BUC1
    • Q9UN54

    Protein attributes for C5orf45 Gene

    343 amino acids
    Molecular mass:
    37743 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAD51611.1; Type=Frameshift; Positions=191; Evidence={ECO:0000305}; Sequence=CAD97932.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for C5orf45 Gene


neXtProt entry for C5orf45 Gene

Proteomics data for C5orf45 Gene at MOPED

Post-translational modifications for C5orf45 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C5orf45 Gene

Domains for C5orf45 Gene

Protein Domains for C5orf45 Gene


Suggested Antigen Peptide Sequences for C5orf45 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q6NTE8
  • Belongs to the UPF0544 family.
genes like me logo Genes that share domains with C5orf45: view

No data available for Gene Families for C5orf45 Gene

Function for C5orf45 Gene

Gene Ontology (GO) - Molecular Function for C5orf45 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with C5orf45: view

Phenotypes for C5orf45 Gene

genes like me logo Genes that share phenotypes with C5orf45: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C5orf45

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C5orf45 Gene

Localization for C5orf45 Gene

Subcellular locations from

Jensen Localization Image for C5orf45 Gene COMPARTMENTS Subcellular localization image for C5orf45 gene
Compartment Confidence
mitochondrion 2
nucleus 2
cytosol 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for C5orf45 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with C5orf45: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C5orf45 Gene

Pathways for C5orf45 Gene

SuperPathways for C5orf45 Gene

No Data Available

Interacting Proteins for C5orf45 Gene

Gene Ontology (GO) - Biological Process for C5orf45 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with C5orf45: view

No data available for Pathways by source for C5orf45 Gene

Transcripts for C5orf45 Gene

Unigene Clusters for C5orf45 Gene

Chromosome 5 open reading frame 45:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C5orf45

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for C5orf45

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C5orf45 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b · 9c · 9d ^ 10a · 10b · 10c · 10d · 10e ^ 11
SP1: - - - - - - - - -
SP2: - - - - -
SP3: - - - - - - - - - -
SP4: - -
SP5: - - - - - - -
SP6: - - - - - - - - - - - -
SP7: - - - - - - - -
SP9: - -
SP11: - - -

Relevant External Links for C5orf45 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C5orf45 Gene

mRNA expression in normal human tissues for C5orf45 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for C5orf45 Gene

SOURCE GeneReport for Unigene cluster for C5orf45 Gene Hs.741169

genes like me logo Genes that share expressions with C5orf45: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C5orf45 Gene

Orthologs for C5orf45 Gene

This gene was present in the common ancestor of animals.

Orthologs for C5orf45 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C5H5orf45 35
  • 99.13 (n)
  • 98.83 (a)
C5orf45 36
  • 99 (a)
(Bos Taurus)
Mammalia C7H5orf45 35
  • 72.07 (n)
  • 60.06 (a)
C7H5orf45 36
  • 53 (a)
(Canis familiaris)
Mammalia C11H5orf45 35
  • 71.26 (n)
  • 57.49 (a)
C5orf45 36
  • 83 (a)
(Mus musculus)
Mammalia 3010026O09Rik 35
  • 67.57 (n)
  • 53.01 (a)
3010026O09Rik 16
3010026O09Rik 36
  • 53 (a)
(Rattus norvegicus)
Mammalia RGD1564036 35
  • 67.94 (n)
  • 51.62 (a)
(Anolis carolinensis)
Reptilia C5orf45 36
  • 46 (a)
(Danio rerio)
Actinopterygii C14H5orf45 36
  • 21 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG43295 36
  • 27 (a)
Species with no ortholog for C5orf45:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C5orf45 Gene

Gene Tree for C5orf45 (if available)
Gene Tree for C5orf45 (if available)

Paralogs for C5orf45 Gene

No data available for Paralogs for C5orf45 Gene

Variants for C5orf45 Gene

Sequence variations from dbSNP and Humsavar for C5orf45 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs155792 -- 179,845,933(+) tcacc(A/G)ctcca intron-variant
rs155793 -- 179,846,265(+) tggaa(C/T)ttttt intron-variant
rs155794 -- 179,846,750(+) CCAAA(A/T)TCTTA intron-variant
rs166034 -- 179,843,497(+) tactt(C/T)gggag intron-variant
rs183648 -- 179,843,614(+) gcaca(C/G)ttgta intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C5orf45 Gene

Variant ID Type Subtype PubMed ID
nsv883270 CNV Loss 21882294
nsv483062 CNV Loss 15286789
nsv469579 CNV Loss 16826518
dgv6400n71 CNV Loss 21882294
nsv883275 CNV Loss 21882294
esv2667626 CNV Deletion 23128226
esv2731309 CNV Deletion 23290073
esv2731310 CNV Deletion 23290073
esv2731311 CNV Deletion 23290073

Relevant External Links for C5orf45 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C5orf45 Gene

Disorders for C5orf45 Gene

No disorders were found for C5orf45 Gene.

No data available for UniProtKB/Swiss-Prot for C5orf45 Gene

Publications for C5orf45 Gene

  1. DNA cloning using in vitro site-specific recombination. (PMID: 11076863) Hartley J.L. … Brasch M.A. (Genome Res. 2000) 3
  2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3

Products for C5orf45 Gene

Sources for C5orf45 Gene

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