C5orf38 Gene
protein-coding GIFtS: 36
GCID: GC05P002806
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chromosome 5 open reading frame 38
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Aliases
for C5orf38 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 5 Open Reading Frame 381 2 | | Coordinated Expression To IRX22 | | CEI1 2 3 | | Coordinated Expression To IRXA2 Homeobox2 | | IRX2NB1 2 | | IRX2 Neighbor2 | | Coordinated Expression To IRXA2 Protein2 3 | | Protein CEI2 |
Export aliases for C5orf38 gene to outside databases |
Summaries
for C5orf38 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C5orf38 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_006576.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C5orf38 gene promoter:
Nkx2-5 CUTL1 c-Ets-1 PPAR-gamma1 POU2F1 COMP1 POU2F1a AP-2beta PPAR-gamma2 AP-2alphaA
Other transcription factors
Search SABiosciences Chromatin IP Primers for C5orf38
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C5orf38 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5p15.33 Ensembl cytogenetic band: 5p15.33 HGNC cytogenetic band: 5p15.33C5orf38 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P002806: view genomic region
(about GC identifiers)
Start:
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2,752,245 bp from pter |
End:
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2,755,511 bp from pter |
Size:
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3,267 bases |
Orientation:
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plus strand |
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Proteins
for C5orf38 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CEI_HUMAN, Q86SI9 (See
protein sequence)Recommended Name: Protein CEI precursor Size: 138 amino acids; 15091 Da
Subcellular location: Secreted (Potential)
Miscellaneous: According to PubMed:16515847, this gene is only represented in primates genome and it is highlyconserved. Also found in bats (according to Ensembl)Alternative splicing: 3 isoforms: Q86SI9-1 Q86SI9-2 Q86SI9-3 Explore the universe of human proteins at neXtProt for C5orf38: NX_Q86SI9
C5orf38 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_848664.1
ENSEMBL proteins: ENSP00000408820 ENSP00000380935 ENSP00000334267 ENSP00000424088 ENSP00000425109 ENSP00000426967 ENSP00000426001
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
IEA | -- |
C5orf38 for ontologies About GeneDecksing
C5orf38 Antibody Products:
Assay Products for C5orf38: |
Protein
Domains /
Families
for C5orf38 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q86SI9 |
Function
for C5orf38 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C5orf38
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C5orf38
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for C5orf38 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C5orf38 |
|
Pathways & Interactions
for C5orf38 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C5orf38
|
Drugs & Compounds
for C5orf38 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C5orf38
Search CenterWatch for drugs/clinical trials and news about C5orf38 / CEI
|
Transcripts
for C5orf38 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C5orf38 gene: NM_178569.2 Unigene Cluster for C5orf38: Chromosome 5 open reading frame 38 Hs.668017 [show with all ESTs]Unigene Representative Sequence: NM_1785697 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000457752 ENST00000397835(uc011cmj.2) ENST00000334000(uc003jdc.3 uc011cmg.2 uc011cmh.2 uc011cmi.2)
ENST00000505106 ENST00000503940 ENST00000505778 ENST00000515640
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C5orf38
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C5orf38
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C5orf38 (NM_178569) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C5orf38 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C5orf38 |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C5orf38
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C5orf38 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C5orf38 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C5orf38 |
Additional cDNA sequence: AY249325.1 BC101608.1 BC101634.1 BC143638.1 BC143639.1 BC143640.1 BC171731.1 3 DOTS entries: DT.91674519 DT.70104390 DT.97836195 9 AceView cDNA sequences: AI939394 AY249325 AI658712 BF198131 CA423794 NM_178569 BX090247 AI199712 BG479754
GeneLoc Exon Structure
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Expression
for C5orf38 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C5orf38 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GACCTGGATC
About this image
See C5orf38 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.668017
UniProtKB/Swiss-Prot: CEI_HUMAN, Q86SI9Tissue specificity: Isoform 1 is highly expressed in small intestine, testis and kidney, medium expressed in brain andheart and low expressed in colon; it could not be detected in liver, adrenal gland and pancreas
SABiosciences Custom PCR Arrays for C5orf38
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C5orf38
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C5orf38 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C5orf38 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C5orf38 |
Orthologs
for C5orf38 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for C5orf38 (if available)
TreeFam Gene Tree for C5orf38 (if available) |
Paralogs
for C5orf38 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C5orf38 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C5orf38 (2752245 - 2755511 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C5orf38: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C5orf38 |
|
Disorders
/ Diseases
for C5orf38 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 C5orf38 for disorders About MalaCards
C5orf38 for disorders About GeneDecksing
OMIM gene information: 610522
OMIM disorders: --
1 disease from the University of Copenhagen DISEASES database for C5orf38:Hypertension Human Genome Epidemiology (HuGE) Navigator: C5orf38 (1 document)
Export disorders for C5orf38 gene to outside databases
|
Publications
for C5orf38 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C5orf38 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C5orf38) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel primate specific gene, CEI, is located in the homeobox gene IRXA2 promoter in Homo sapiens. (PubMed id 16515847)1, 2, 3 Wu Q.... Hansen L. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for C5orf38 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing C5orf38 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C5orf38 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C5orf38 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C5orf38 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for C5orf38 gene:
Search GeneIP for patents involving C5orf38
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C5orf38 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C5orf38 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C5orf38 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C5orf38 | | | OriGene Protein Over-expression Lysate for C5orf38 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C5orf38 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C5orf38 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C5orf38 | | OriGene Custom Protein Services for C5orf38 | | | OriGene Custom Immunoassay Development | | |
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 | | | C5orf38 Proteins, Antibodies, CLIAs, and ELISAs |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C5orf38 |
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