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Aliases for C5orf38 Gene

Aliases for C5orf38 Gene

  • Chromosome 5 Open Reading Frame 38 2 3
  • CEI 3 4 6
  • Coordinated Expression To IRXA2 Protein 3 4
  • Coordinated Expression To IRX2 2 3
  • IRX2 Neighbor 2 3
  • Coordinated Expression To IRXA2 Homeobox 3
  • Protein CEI 3
  • IRX2NB 3

External Ids for C5orf38 Gene

Previous GeneCards Identifiers for C5orf38 Gene

  • GC05P002806

Summaries for C5orf38 Gene

GeneCards Summary for C5orf38 Gene

C5orf38 (Chromosome 5 Open Reading Frame 38) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C5orf38 Gene

Genomics for C5orf38 Gene

Regulatory Elements for C5orf38 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C5orf38 Gene

Start:
2,751,944 bp from pter
End:
2,755,397 bp from pter
Size:
3,454 bases
Orientation:
Plus strand

Genomic View for C5orf38 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C5orf38 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C5orf38 Gene

Proteins for C5orf38 Gene

  • Protein details for C5orf38 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86SI9-CEI_HUMAN
    Recommended name:
    Protein CEI
    Protein Accession:
    Q86SI9
    Secondary Accessions:

    Protein attributes for C5orf38 Gene

    Size:
    138 amino acids
    Molecular mass:
    15091 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • According to PubMed:16515847, this gene is only represented in primates genome and it is highly conserved. Also found in bats (according to Ensembl)

    Alternative splice isoforms for C5orf38 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C5orf38 Gene

Proteomics data for C5orf38 Gene at MOPED

Post-translational modifications for C5orf38 Gene

No Post-translational modifications

Other Protein References for C5orf38 Gene

No data available for DME Specific Peptides for C5orf38 Gene

Domains for C5orf38 Gene

Protein Domains for C5orf38 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for C5orf38 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C5orf38: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C5orf38 Gene

Function for C5orf38 Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C5orf38

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C5orf38 Gene

Localization for C5orf38 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C5orf38 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C5orf38 Gene COMPARTMENTS Subcellular localization image for C5orf38 gene
Compartment Confidence
extracellular 3
mitochondrion 2
cytosol 1
nucleus 1

Gene Ontology (GO) - Cellular Components for C5orf38 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with C5orf38: view

Pathways for C5orf38 Gene

SuperPathways for C5orf38 Gene

No Data Available

Interacting Proteins for C5orf38 Gene

Gene Ontology (GO) - Biological Process for C5orf38 Gene

None

No data available for Pathways by source for C5orf38 Gene

Transcripts for C5orf38 Gene

mRNA/cDNA for C5orf38 Gene

Unigene Clusters for C5orf38 Gene

Chromosome 5 open reading frame 38:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C5orf38

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for C5orf38
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C5orf38 Gene

No ASD Table

Relevant External Links for C5orf38 Gene

GeneLoc Exon Structure for
C5orf38
ECgene alternative splicing isoforms for
C5orf38

Expression for C5orf38 Gene

mRNA expression in normal human tissues for C5orf38 Gene

mRNA differential expression in normal tissues according to GTEx for C5orf38 Gene

This gene is overexpressed in Minor Salivary Gland (5.4) and Stomach (4.3).

SOURCE GeneReport for Unigene cluster for C5orf38 Gene Hs.668017

mRNA Expression by UniProt/SwissProt for C5orf38 Gene

Q86SI9-CEI_HUMAN
Tissue specificity: Isoform 1 is highly expressed in small intestine, testis and kidney, medium expressed in brain and heart and low expressed in colon; it could not be detected in liver, adrenal gland and pancreas.
genes like me logo Genes that share expressions with C5orf38: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Protein expression for C5orf38 Gene

Orthologs for C5orf38 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C5orf38 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C5H5orf38 35
  • 99.03 (n)
  • 97.83 (a)
C5orf38 36
  • 51 (a)
OneToOne
Species with no ortholog for C5orf38:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C5orf38 Gene

ENSEMBL:
Gene Tree for C5orf38 (if available)
TreeFam:
Gene Tree for C5orf38 (if available)

Paralogs for C5orf38 Gene

No data available for Paralogs for C5orf38 Gene

Variants for C5orf38 Gene

Sequence variations from dbSNP and Humsavar for C5orf38 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs2935599 -- 2,754,566(-) AAGAA(A/G)ACCAA intron-variant
rs4866489 -- 2,754,675(+) AGCCC(A/G)GACTC intron-variant
rs4866667 -- 2,755,818(+) TCAAC(C/T)GGCAT intron-variant, downstream-variant-500B
rs4866668 -- 2,755,851(+) CCGAG(A/G)CCTAA intron-variant, downstream-variant-500B
rs56378742 -- 2,754,225(+) TCCCC(-/T)CCTCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C5orf38 Gene

Variant ID Type Subtype PubMed ID
dgv931n67 CNV Gain 20364138
nsv822972 CNV Gain 20364138
nsv461913 CNV Loss 19166990
nsv822977 CNV Gain 20364138

Relevant External Links for C5orf38 Gene

HapMap Linkage Disequilibrium report
C5orf38

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C5orf38 Gene

Disorders for C5orf38 Gene

(1) University of Copenhagen DISEASES for C5orf38 Gene

Relevant External Links for C5orf38

Genetic Association Database (GAD)
C5orf38
Human Genome Epidemiology (HuGE) Navigator
C5orf38
genes like me logo Genes that share disorders with C5orf38: view

No data available for UniProtKB/Swiss-Prot for C5orf38 Gene

Publications for C5orf38 Gene

  1. A novel primate specific gene, CEI, is located in the homeobox gene IRXA2 promoter in Homo sapiens. (PMID: 16515847) Wu Q. … Hansen L. (Gene 2006) 2 3 4
  2. [High-resolution analysis of chromosome 5 and identification of candidate genes in gastric cancer]. (PMID: 16750006) Yu Y.Y. … Lin Y.Z. (Zhonghua Zhong Liu Za Zhi 2006) 2 3
  3. Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data. (PMID: 17362836) Schymick J.C. … Traynor B.J. (Lancet Neurol 2007) 48
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for C5orf38 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate C5orf38
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for C5orf38
    • Block miRNA regulation of C5orf38 using miScript Target Protectors

    Sources for C5orf38 Gene

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