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Aliases for C5orf34 Gene

Aliases for C5orf34 Gene

  • Chromosome 5 Open Reading Frame 34 2 3 5

External Ids for C5orf34 Gene

Previous GeneCards Identifiers for C5orf34 Gene

  • GC05M043524
  • GC05M043525
  • GC05M043487
  • GC05M043437
  • GC05M043488
  • GC05M043490
  • GC05M043491
  • GC05M043492

Summaries for C5orf34 Gene

GeneCards Summary for C5orf34 Gene

C5orf34 (Chromosome 5 Open Reading Frame 34) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C5orf34 Gene

Genomics for C5orf34 Gene

Regulatory Elements for C5orf34 Gene

Enhancers for C5orf34 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around C5orf34 on UCSC Golden Path with GeneCards custom track

Promoters for C5orf34 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for C5orf34 Gene

43,486,701 bp from pter
43,515,171 bp from pter
28,471 bases
Minus strand

Genomic View for C5orf34 Gene

Genes around C5orf34 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C5orf34 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C5orf34 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C5orf34 Gene

Proteins for C5orf34 Gene

  • Protein details for C5orf34 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C5orf34
    Protein Accession:

    Protein attributes for C5orf34 Gene

    638 amino acids
    Molecular mass:
    72898 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C5orf34 Gene

Post-translational modifications for C5orf34 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C5orf34 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C5orf34 Gene

Domains & Families for C5orf34 Gene

Protein Domains for C5orf34 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C5orf34: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C5orf34 Gene

Function for C5orf34 Gene

Phenotypes for C5orf34 Gene

genes like me logo Genes that share phenotypes with C5orf34: view

Animal Model Products

CRISPR Products

miRNA for C5orf34 Gene

miRTarBase miRNAs that target C5orf34

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C5orf34 Gene

Localization for C5orf34 Gene

Subcellular locations from

Jensen Localization Image for C5orf34 Gene COMPARTMENTS Subcellular localization image for C5orf34 gene
Compartment Confidence
cytosol 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C5orf34 Gene

Pathways & Interactions for C5orf34 Gene

SuperPathways for C5orf34 Gene

No Data Available

Interacting Proteins for C5orf34 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000303490 Q96MH7-CE034_HUMAN for C5orf34 Gene via STRING IID

Gene Ontology (GO) - Biological Process for C5orf34 Gene


No data available for Pathways by source and SIGNOR curated interactions for C5orf34 Gene

Drugs & Compounds for C5orf34 Gene

No Compound Related Data Available

Transcripts for C5orf34 Gene

Unigene Clusters for C5orf34 Gene

Chromosome 5 open reading frame 34:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C5orf34 Gene

No ASD Table

Relevant External Links for C5orf34 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C5orf34 Gene

mRNA expression in normal human tissues for C5orf34 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for C5orf34 Gene

This gene is overexpressed in Ovary (65.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C5orf34 Gene

Protein tissue co-expression partners for C5orf34 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C5orf34 Gene:


SOURCE GeneReport for Unigene cluster for C5orf34 Gene:

genes like me logo Genes that share expression patterns with C5orf34: view

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C5orf34 Gene

Orthologs for C5orf34 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C5orf34 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C20H5orf34 34
  • 86.88 (n)
  • 80.94 (a)
C20H5orf34 35
  • 80 (a)
(Canis familiaris)
Mammalia C4H5orf34 34
  • 88.17 (n)
  • 84.62 (a)
C5orf34 35
  • 84 (a)
(Mus musculus)
Mammalia 4833420G17Rik 34
  • 80.26 (n)
  • 75.59 (a)
4833420G17Rik 16
4833420G17Rik 35
  • 75 (a)
(Pan troglodytes)
Mammalia C5H5orf34 34
  • 99.27 (n)
  • 99.06 (a)
C5orf34 35
  • 99 (a)
(Rattus norvegicus)
Mammalia RGD1306227 34
  • 79.21 (n)
  • 74.17 (a)
(Monodelphis domestica)
Mammalia C5orf34 35
  • 64 (a)
(Ornithorhynchus anatinus)
Mammalia C5orf34 35
  • 56 (a)
(Gallus gallus)
Aves CZH5ORF34 34
  • 59.93 (n)
  • 50.24 (a)
C5orf34 35
  • 48 (a)
(Anolis carolinensis)
Reptilia C5orf34 35
  • 46 (a)
(Danio rerio)
Actinopterygii zgc:153352 34
  • 48.82 (n)
  • 39.62 (a)
C5H5orf34 35
  • 34 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 24 (a)
Species where no ortholog for C5orf34 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C5orf34 Gene

Gene Tree for C5orf34 (if available)
Gene Tree for C5orf34 (if available)

Paralogs for C5orf34 Gene

No data available for Paralogs for C5orf34 Gene

Variants for C5orf34 Gene

Sequence variations from dbSNP and Humsavar for C5orf34 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
VAR_035618 A breast cancer sample
VAR_061589 -

Structural Variations from Database of Genomic Variants (DGV) for C5orf34 Gene

Variant ID Type Subtype PubMed ID
esv3604904 CNV gain 21293372
nsv830275 CNV gain 17160897
nsv964848 CNV duplication 23825009

Variation tolerance for C5orf34 Gene

Residual Variation Intolerance Score: 44.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.03; 37.40% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C5orf34 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C5orf34 Gene

Disorders for C5orf34 Gene

Relevant External Links for C5orf34

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C5orf34 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C5orf34 Gene

Publications for C5orf34 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 65
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 65
  4. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. (PMID: 26673895) KA+rlA+ K. … GAPrlich D. (Elife 2015) 3 65
  5. The consensus coding sequences of human breast and colorectal cancers. (PMID: 16959974) Sjoeblom T. … Velculescu V.E. (Science 2006) 4 65

Products for C5orf34 Gene

Sources for C5orf34 Gene

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