Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C5orf34 Gene

Aliases for C5orf34 Gene

  • Chromosome 5 Open Reading Frame 34 2 3

External Ids for C5orf34 Gene

Previous GeneCards Identifiers for C5orf34 Gene

  • GC05M043524
  • GC05M043525
  • GC05M043487
  • GC05M043437
  • GC05M043488

Summaries for C5orf34 Gene

GeneCards Summary for C5orf34 Gene

C5orf34 (Chromosome 5 Open Reading Frame 34) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C5orf34 Gene

Genomics for C5orf34 Gene

Regulatory Elements for C5orf34 Gene

Genomic Location for C5orf34 Gene

Start:
43,486,701 bp from pter
End:
43,515,445 bp from pter
Size:
28,745 bases
Orientation:
Minus strand

Genomic View for C5orf34 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C5orf34 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C5orf34 Gene

Proteins for C5orf34 Gene

  • Protein details for C5orf34 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96MH7-CE034_HUMAN
    Recommended name:
    Uncharacterized protein C5orf34
    Protein Accession:
    Q96MH7
    Secondary Accessions:

    Protein attributes for C5orf34 Gene

    Size:
    638 amino acids
    Molecular mass:
    72898 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C5orf34 Gene

Proteomics data for C5orf34 Gene at MOPED

Post-translational modifications for C5orf34 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C5orf34 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C5orf34 Gene

Domains for C5orf34 Gene

Protein Domains for C5orf34 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C5orf34: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C5orf34 Gene

Function for C5orf34 Gene

Animal Model Products

CRISPR Products

miRNA for C5orf34 Gene

miRTarBase miRNAs that target C5orf34

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C5orf34

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for C5orf34 Gene

Localization for C5orf34 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C5orf34 Gene COMPARTMENTS Subcellular localization image for C5orf34 gene
Compartment Confidence
cytosol 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C5orf34 Gene

Pathways for C5orf34 Gene

SuperPathways for C5orf34 Gene

No Data Available

Interacting Proteins for C5orf34 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000303490%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000303490 for C5orf34 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for C5orf34 Gene

None

No data available for Pathways by source for C5orf34 Gene

Transcripts for C5orf34 Gene

Unigene Clusters for C5orf34 Gene

Chromosome 5 open reading frame 34:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C5orf34

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C5orf34 Gene

No ASD Table

Relevant External Links for C5orf34 Gene

GeneLoc Exon Structure for
C5orf34
ECgene alternative splicing isoforms for
C5orf34

Expression for C5orf34 Gene

mRNA expression in normal human tissues for C5orf34 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for C5orf34 Gene

This gene is overexpressed in Ovary (65.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C5orf34 Gene

SOURCE GeneReport for Unigene cluster for C5orf34 Gene Hs.661641

genes like me logo Genes that share expressions with C5orf34: view

Expression partners for C5orf34 Gene

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C5orf34 Gene

Orthologs for C5orf34 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C5orf34 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C20H5orf34 35
  • 86.88 (n)
  • 80.94 (a)
C20H5orf34 36
  • 80 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C4H5orf34 35
  • 88.17 (n)
  • 84.62 (a)
C5orf34 36
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 4833420G17Rik 35
  • 80.26 (n)
  • 75.59 (a)
4833420G17Rik 16
4833420G17Rik 36
  • 75 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C5H5orf34 35
  • 99.27 (n)
  • 99.06 (a)
C5orf34 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1306227 35
  • 79.21 (n)
  • 74.17 (a)
oppossum
(Monodelphis domestica)
Mammalia C5orf34 36
  • 64 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C5orf34 36
  • 56 (a)
OneToOne
chicken
(Gallus gallus)
Aves CZH5ORF34 35
  • 59.93 (n)
  • 50.24 (a)
C5orf34 36
  • 48 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C5orf34 36
  • 46 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii zgc:153352 35
  • 48.82 (n)
  • 39.62 (a)
C5H5orf34 36
  • 34 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 24 (a)
OneToOne
Species with no ortholog for C5orf34:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C5orf34 Gene

ENSEMBL:
Gene Tree for C5orf34 (if available)
TreeFam:
Gene Tree for C5orf34 (if available)

Paralogs for C5orf34 Gene

No data available for Paralogs for C5orf34 Gene

Variants for C5orf34 Gene

Sequence variations from dbSNP and Humsavar for C5orf34 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs3776423 -- 43,487,772(+) CAATC(G/T)TAGGT intron-variant
rs3836781 -- 43,488,029(+) CTGAC(-/T)TTTTT intron-variant
rs4074777 -- 43,504,646(+) TTGCT(A/G)AAGTC intron-variant
rs4331909 -- 43,517,130(+) ctgct(A/G)tattc upstream-variant-2KB
rs4481352 -- 43,504,881(+) ACAAG(C/T)CTAAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C5orf34 Gene

Variant ID Type Subtype PubMed ID
dgv6043n71 CNV Gain 21882294
nsv830275 CNV Gain 17160897

Relevant External Links for C5orf34 Gene

HapMap Linkage Disequilibrium report
C5orf34

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C5orf34 Gene

Disorders for C5orf34 Gene

Relevant External Links for C5orf34

Genetic Association Database (GAD)
C5orf34

No disorders were found for C5orf34 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for C5orf34 Gene

Publications for C5orf34 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  4. Global identification of modular cullin-RING ligase substrates. (PMID: 21963094) Emanuele M.J. … Elledge S.J. (Cell 2011) 3
  5. Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. (PMID: 21987572) Lee K.A. … Doedens J.R. (J. Biol. Chem. 2011) 3

Products for C5orf34 Gene

Sources for C5orf34 Gene

Back to Top

Content