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Aliases for C5orf30 Gene

Aliases for C5orf30 Gene

  • Chromosome 5 Open Reading Frame 30 2 3

External Ids for C5orf30 Gene

Summaries for C5orf30 Gene

GeneCards Summary for C5orf30 Gene

C5orf30 (Chromosome 5 Open Reading Frame 30) is a Protein Coding gene.

UniProtKB/Swiss-Prot for C5orf30 Gene

  • Probably plays a role in trafficking of proteins via its interaction with UNC119 and UNC119B cargo adapters: may help the release of UNC119 and UNC119B cargo or the recycling of UNC119 and UNC119B. May play a role in ciliary membrane localization via its interaction with UNC119B and protein transport into photoreceptor cells.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C5orf30 Gene

Genomics for C5orf30 Gene

Genomic Location for C5orf30 Gene

Start:
103,258,702 bp from pter
End:
103,278,660 bp from pter
Size:
19,959 bases
Orientation:
Plus strand

Genomic View for C5orf30 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C5orf30 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C5orf30 Gene

Regulatory Elements for C5orf30 Gene

Proteins for C5orf30 Gene

  • Protein details for C5orf30 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96GV9-CE030_HUMAN
    Recommended name:
    UNC119-binding protein C5orf30
    Protein Accession:
    Q96GV9
    Secondary Accessions:

    Protein attributes for C5orf30 Gene

    Size:
    206 amino acids
    Molecular mass:
    23083 Da
    Quaternary structure:
    • Interacts with UNC119 and UNC119B; interaction preferentially takes place when UNC119 and UNC119B are unliganded with myristoylated proteins.

neXtProt entry for C5orf30 Gene

Proteomics data for C5orf30 Gene at MOPED

Post-translational modifications for C5orf30 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C5orf30 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C5orf30 Gene

Domains for C5orf30 Gene

Protein Domains for C5orf30 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C5orf30 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96GV9

UniProtKB/Swiss-Prot:

CE030_HUMAN
Family:
  • Belongs to the UNC119-binding protein family.:
    • Q96GV9
genes like me logo Genes that share domains with C5orf30: view

No data available for Gene Families for C5orf30 Gene

Function for C5orf30 Gene

Molecular function for C5orf30 Gene

UniProtKB/Swiss-Prot Function: Probably plays a role in trafficking of proteins via its interaction with UNC119 and UNC119B cargo adapters: may help the release of UNC119 and UNC119B cargo or the recycling of UNC119 and UNC119B. May play a role in ciliary membrane localization via its interaction with UNC119B and protein transport into photoreceptor cells.

Gene Ontology (GO) - Molecular Function for C5orf30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 22085962
genes like me logo Genes that share ontologies with C5orf30: view

Phenotypes for C5orf30 Gene

GenomeRNAi human phenotypes for C5orf30:
genes like me logo Genes that share phenotypes with C5orf30: view

miRNA for C5orf30 Gene

miRTarBase miRNAs that target C5orf30

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for C5orf30 Gene

Localization for C5orf30 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C5orf30 Gene

Cytoplasm. Cell projection, cilium. Note=Localizes to the transition zone and proximal cilium in addition to being found throughout the cytoplasm.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C5orf30 Gene COMPARTMENTS Subcellular localization image for C5orf30 gene
Compartment Confidence
nucleus 3
cytosol 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for C5orf30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA 22085962
GO:0035869 ciliary transition zone IDA 22085962
genes like me logo Genes that share ontologies with C5orf30: view

Pathways for C5orf30 Gene

SuperPathways for C5orf30 Gene

No Data Available

Interacting Proteins for C5orf30 Gene

Selected Interacting proteins: Q96GV9-CE030_HUMAN for C5orf30 Gene via UniProtKB I2D

Gene Ontology (GO) - Biological Process for C5orf30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015031 protein transport IEA --
GO:0060271 cilium morphogenesis ISS --
genes like me logo Genes that share ontologies with C5orf30: view

No data available for Pathways by source for C5orf30 Gene

Transcripts for C5orf30 Gene

Unigene Clusters for C5orf30 Gene

Chromosome 5 open reading frame 30:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C5orf30 Gene

No ASD Table

Relevant External Links for C5orf30 Gene

GeneLoc Exon Structure for
C5orf30
ECgene alternative splicing isoforms for
C5orf30

Expression for C5orf30 Gene

mRNA expression in normal human tissues for C5orf30 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for C5orf30 Gene

SOURCE GeneReport for Unigene cluster for C5orf30 Gene Hs.482976

genes like me logo Genes that share expressions with C5orf30: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C5orf30 Gene

Orthologs for C5orf30 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C5orf30 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C5H5orf30 35
  • 99.19 (n)
  • 99.51 (a)
C5orf30 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C7H5orf30 35
  • 92.07 (n)
  • 95.63 (a)
C7H5orf30 36
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C3H5orf30 35
  • 77.61 (n)
  • 84.8 (a)
C5orf30 36
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia D1Ertd622e 35
  • 89.16 (n)
  • 94.66 (a)
D1Ertd622e 16
D1Ertd622e 36
  • 94 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C5orf30 36
  • 91 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C5orf30 36
  • 85 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1562136 35
  • 87.54 (n)
  • 94.66 (a)
chicken
(Gallus gallus)
Aves C5ORF30 35
  • 79.61 (n)
  • 89.32 (a)
C5orf30 36
  • 89 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C5orf30 36
  • 86 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.20270 35
tropical clawed frog
(Silurana tropicalis)
Amphibia c5orf30 35
  • 75.98 (n)
  • 79.9 (a)
zebrafish
(Danio rerio)
Actinopterygii C10H5orf30 36
  • 72 (a)
OneToOne
zgc:194281 35
  • 68.3 (n)
  • 72.55 (a)
Species with no ortholog for C5orf30:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C5orf30 Gene

ENSEMBL:
Gene Tree for C5orf30 (if available)
TreeFam:
Gene Tree for C5orf30 (if available)

Paralogs for C5orf30 Gene

No data available for Paralogs for C5orf30 Gene

Variants for C5orf30 Gene

Sequence variations from dbSNP and Humsavar for C5orf30 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs15378 -- 103,278,099(-) AGTAA(A/G)ATATG utr-variant-3-prime
rs26232 -- 103,261,019(+) TGAAA(C/T)TGAGT intron-variant
rs26233 -- 103,261,115(+) ATAAT(G/T)AGTGC intron-variant
rs26234 -- 103,261,455(+) AGTTA(A/G)TATTC intron-variant
rs28157 -- 103,260,136(-) CCATT(A/C)TTCCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C5orf30 Gene

Variant ID Type Subtype PubMed ID
nsv882519 CNV Loss 21882294
nsv882522 CNV Loss 21882294
nsv4936 CNV Insertion 18451855
nsv507280 CNV Insertion 20534489

Relevant External Links for C5orf30 Gene

HapMap Linkage Disequilibrium report
C5orf30

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C5orf30 Gene

Disorders for C5orf30 Gene

Relevant External Links for C5orf30

Genetic Association Database (GAD)
C5orf30
Human Genome Epidemiology (HuGE) Navigator
C5orf30
genes like me logo Genes that share disorders with C5orf30: view

No data available for UniProtKB/Swiss-Prot for C5orf30 Gene

Publications for C5orf30 Gene

  1. An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium. (PMID: 22085962) Wright K.J. … Jackson P.K. (Genes Dev. 2011) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. (PMID: 20453842) Stahl E.A. … Plenge R.M. (Nat. Genet. 2010) 3 48
  4. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3
  5. An empirical framework for binary interactome mapping. (PMID: 19060904) Venkatesan K. … Vidal M. (Nat. Methods 2009) 3

Products for C5orf30 Gene

Sources for C5orf30 Gene

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