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Aliases for C5orf24 Gene

Aliases for C5orf24 Gene

  • Chromosome 5 Open Reading Frame 24 2 3

External Ids for C5orf24 Gene

Previous GeneCards Identifiers for C5orf24 Gene

  • GC05P134210
  • GC05P129367
  • GC05P134181

Summaries for C5orf24 Gene

GeneCards Summary for C5orf24 Gene

C5orf24 (Chromosome 5 Open Reading Frame 24) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C5orf24 Gene

Genomics for C5orf24 Gene

Regulatory Elements for C5orf24 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C5orf24 Gene

134,845,680 bp from pter
134,859,737 bp from pter
14,058 bases
Plus strand

Genomic View for C5orf24 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C5orf24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C5orf24 Gene

Proteins for C5orf24 Gene

  • Protein details for C5orf24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UPF0461 protein C5orf24
    Protein Accession:
    Secondary Accessions:
    • D3DQA7
    • Q86Y53
    • Q8N1T9

    Protein attributes for C5orf24 Gene

    188 amino acids
    Molecular mass:
    20132 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C5orf24 Gene


neXtProt entry for C5orf24 Gene

Proteomics data for C5orf24 Gene at MOPED

Post-translational modifications for C5orf24 Gene

  • Ubiquitination at Lys 41 and Lys 146
  • Modification sites at PhosphoSitePlus

Other Protein References for C5orf24 Gene

No data available for DME Specific Peptides for C5orf24 Gene

Domains & Families for C5orf24 Gene

Protein Domains for C5orf24 Gene


Suggested Antigen Peptide Sequences for C5orf24 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the UPF0461 family.
  • Belongs to the UPF0461 family.
genes like me logo Genes that share domains with C5orf24: view

No data available for Gene Families for C5orf24 Gene

Function for C5orf24 Gene

Gene Ontology (GO) - Molecular Function for C5orf24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C5orf24: view

Phenotypes for C5orf24 Gene

genes like me logo Genes that share phenotypes with C5orf24: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C5orf24

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for C5orf24 Gene

Localization for C5orf24 Gene

Subcellular locations from

Jensen Localization Image for C5orf24 Gene COMPARTMENTS Subcellular localization image for C5orf24 gene
Compartment Confidence
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C5orf24 Gene

Pathways & Interactions for C5orf24 Gene

SuperPathways for C5orf24 Gene

No Data Available

Interacting Proteins for C5orf24 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: Q7Z6I8-CE024_HUMAN ENSP00000337044 for C5orf24 Gene via UniProtKB STRING

Gene Ontology (GO) - Biological Process for C5orf24 Gene


No data available for Pathways by source and SIGNOR curated interactions for C5orf24 Gene

Drugs & Compounds for C5orf24 Gene

No Compound Related Data Available

Transcripts for C5orf24 Gene

Unigene Clusters for C5orf24 Gene

Chromosome 5 open reading frame 24:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C5orf24

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C5orf24 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c · 4d · 4e · 4f ^ 5a · 5b
SP1: - - - -
SP3: - - - -
SP4: - - - -
SP5: -

Relevant External Links for C5orf24 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C5orf24 Gene

mRNA expression in normal human tissues for C5orf24 Gene

Protein differential expression in normal tissues from HIPED for C5orf24 Gene

This gene is overexpressed in Serum (19.5), Fetal Brain (13.6), and Blymphocyte (10.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for C5orf24 Gene

SOURCE GeneReport for Unigene cluster for C5orf24 Gene Hs.708536

genes like me logo Genes that share expression patterns with C5orf24: view

Protein tissue co-expression partners for C5orf24 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C5orf24 Gene

Orthologs for C5orf24 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C5orf24 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C7H5orf24 35
  • 95.39 (n)
  • 96.81 (a)
C7H5orf24 36
  • 97 (a)
(Canis familiaris)
Mammalia C11H5orf24 35
  • 95.04 (n)
  • 97.87 (a)
C5orf24 36
  • 98 (a)
(Mus musculus)
Mammalia B230219D22Rik 35
  • 91.49 (n)
  • 93.62 (a)
B230219D22Rik 16
B230219D22Rik 36
  • 93 (a)
(Pan troglodytes)
Mammalia C5H5orf24 35
  • 99.65 (n)
  • 100 (a)
C5orf24 36
  • 100 (a)
(Rattus norvegicus)
Mammalia RGD1566359 35
  • 89.36 (n)
  • 90.96 (a)
(Monodelphis domestica)
Mammalia C5orf24 36
  • 86 (a)
(Ornithorhynchus anatinus)
Mammalia C5orf24 36
  • 76 (a)
(Gallus gallus)
Aves C13H5ORF24 35
  • 82.62 (n)
  • 84.04 (a)
C5orf24 36
  • 81 (a)
(Anolis carolinensis)
Reptilia C5orf24 36
  • 79 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c5orf24 35
  • 74.91 (n)
  • 71.51 (a)
(Danio rerio)
Actinopterygii LOC797133 35
  • 59.88 (n)
  • 60.48 (a)
C21H5orf24 (2 of 2) 36
  • 35 (a)
C5orf24 (1 of 2) 36
  • 46 (a)
Species with no ortholog for C5orf24:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C5orf24 Gene

Gene Tree for C5orf24 (if available)
Gene Tree for C5orf24 (if available)

Paralogs for C5orf24 Gene

No data available for Paralogs for C5orf24 Gene

Variants for C5orf24 Gene

Structural Variations from Database of Genomic Variants (DGV) for C5orf24 Gene

Variant ID Type Subtype PubMed ID
nsv830493 CNV Loss 17160897
nsv523937 CNV Gain 19592680
nsv830494 CNV Gain+Loss 17160897

Variation tolerance for C5orf24 Gene

Residual Variation Intolerance Score: 31.32% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.66; 14.12% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C5orf24 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for C5orf24 Gene

Disorders for C5orf24 Gene

Relevant External Links for C5orf24

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C5orf24: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C5orf24 Gene

Publications for C5orf24 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. Uncovering global SUMOylation signaling networks in a site-specific manner. (PMID: 25218447) Hendriks I.A. … Vertegaal A.C. (Nat. Struct. Mol. Biol. 2014) 67
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 67
  5. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. (PMID: 17525332) Matsuoka S. … Elledge S.J. (Science 2007) 67

Products for C5orf24 Gene

Sources for C5orf24 Gene

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