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Aliases for C5orf24 Gene

Aliases for C5orf24 Gene

  • Chromosome 5 Open Reading Frame 24 2 3 5

External Ids for C5orf24 Gene

Previous GeneCards Identifiers for C5orf24 Gene

  • GC05P134210
  • GC05P129367
  • GC05P134181

Summaries for C5orf24 Gene

GeneCards Summary for C5orf24 Gene

C5orf24 (Chromosome 5 Open Reading Frame 24) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C5orf24 Gene

Genomics for C5orf24 Gene

Regulatory Elements for C5orf24 Gene

Enhancers for C5orf24 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around C5orf24 on UCSC Golden Path with GeneCards custom track

Promoters for C5orf24 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C5orf24 on UCSC Golden Path with GeneCards custom track

Genomic Location for C5orf24 Gene

134,845,680 bp from pter
134,859,737 bp from pter
14,058 bases
Plus strand

Genomic View for C5orf24 Gene

Genes around C5orf24 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C5orf24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C5orf24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C5orf24 Gene

Proteins for C5orf24 Gene

  • Protein details for C5orf24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UPF0461 protein C5orf24
    Protein Accession:
    Secondary Accessions:
    • D3DQA7
    • Q86Y53
    • Q8N1T9

    Protein attributes for C5orf24 Gene

    188 amino acids
    Molecular mass:
    20132 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C5orf24 Gene


neXtProt entry for C5orf24 Gene

Post-translational modifications for C5orf24 Gene

  • Ubiquitination at Lys 41 and Lys 146
  • Modification sites at PhosphoSitePlus

Other Protein References for C5orf24 Gene

No data available for DME Specific Peptides for C5orf24 Gene

Domains & Families for C5orf24 Gene

Protein Domains for C5orf24 Gene


Suggested Antigen Peptide Sequences for C5orf24 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the UPF0461 family.
  • Belongs to the UPF0461 family.
genes like me logo Genes that share domains with C5orf24: view

No data available for Gene Families for C5orf24 Gene

Function for C5orf24 Gene

Gene Ontology (GO) - Molecular Function for C5orf24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C5orf24: view
genes like me logo Genes that share phenotypes with C5orf24: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C5orf24 Gene

Localization for C5orf24 Gene

Subcellular locations from

Jensen Localization Image for C5orf24 Gene COMPARTMENTS Subcellular localization image for C5orf24 gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C5orf24 Gene

Pathways & Interactions for C5orf24 Gene

SuperPathways for C5orf24 Gene

No Data Available

Interacting Proteins for C5orf24 Gene

Gene Ontology (GO) - Biological Process for C5orf24 Gene


No data available for Pathways by source and SIGNOR curated interactions for C5orf24 Gene

Drugs & Compounds for C5orf24 Gene

No Compound Related Data Available

Transcripts for C5orf24 Gene

Unigene Clusters for C5orf24 Gene

Chromosome 5 open reading frame 24:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C5orf24 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c · 4d · 4e · 4f ^ 5a · 5b
SP1: - - - -
SP3: - - - -
SP4: - - - -
SP5: -

Relevant External Links for C5orf24 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C5orf24 Gene

mRNA expression in normal human tissues for C5orf24 Gene

Protein differential expression in normal tissues from HIPED for C5orf24 Gene

This gene is overexpressed in Serum (19.5), Fetal Brain (13.6), and Blymphocyte (10.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C5orf24 Gene

Protein tissue co-expression partners for C5orf24 Gene

NURSA nuclear receptor signaling pathways regulating expression of C5orf24 Gene:


SOURCE GeneReport for Unigene cluster for C5orf24 Gene:

genes like me logo Genes that share expression patterns with C5orf24: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C5orf24 Gene

Orthologs for C5orf24 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C5orf24 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C7H5orf24 34
  • 95.39 (n)
  • 96.81 (a)
C7H5orf24 35
  • 97 (a)
(Canis familiaris)
Mammalia C11H5orf24 34
  • 95.04 (n)
  • 97.87 (a)
C5orf24 35
  • 98 (a)
(Mus musculus)
Mammalia B230219D22Rik 34
  • 91.49 (n)
  • 93.62 (a)
B230219D22Rik 16
B230219D22Rik 35
  • 93 (a)
(Pan troglodytes)
Mammalia C5H5orf24 34
  • 99.65 (n)
  • 100 (a)
C5orf24 35
  • 100 (a)
(Rattus norvegicus)
Mammalia RGD1566359 34
  • 89.36 (n)
  • 90.96 (a)
(Monodelphis domestica)
Mammalia C5orf24 35
  • 86 (a)
(Ornithorhynchus anatinus)
Mammalia C5orf24 35
  • 76 (a)
(Gallus gallus)
Aves C13H5ORF24 34
  • 82.62 (n)
  • 84.04 (a)
C5orf24 35
  • 81 (a)
(Anolis carolinensis)
Reptilia C5orf24 35
  • 79 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c5orf24 34
  • 74.91 (n)
  • 71.51 (a)
(Danio rerio)
Actinopterygii LOC797133 34
  • 59.88 (n)
  • 60.48 (a)
C21H5orf24 (2 of 2) 35
  • 35 (a)
C5orf24 (1 of 2) 35
  • 46 (a)
Species where no ortholog for C5orf24 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C5orf24 Gene

Gene Tree for C5orf24 (if available)
Gene Tree for C5orf24 (if available)

Paralogs for C5orf24 Gene

No data available for Paralogs for C5orf24 Gene

Variants for C5orf24 Gene

Sequence variations from dbSNP and Humsavar for C5orf24 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1468606 -- 134,849,518(+) TCTCA(C/T)ATTAA intron-variant
rs4418145 -- 134,859,079(+) AAATA(A/C)CCATA utr-variant-3-prime
rs15236 -- 134,858,862(-) TGATT(A/T)TTTAA utr-variant-3-prime
rs17695346 -- 134,858,923(+) GAAAC(A/C)TCTGT utr-variant-3-prime
rs7700841 -- 134,854,895(+) TTTGG(C/T)AGAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C5orf24 Gene

Variant ID Type Subtype PubMed ID
dgv5810n100 CNV gain 25217958
nsv523937 CNV gain 19592680
nsv830493 CNV loss 17160897
nsv830494 CNV gain+loss 17160897

Variation tolerance for C5orf24 Gene

Residual Variation Intolerance Score: 31.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.66; 14.12% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C5orf24 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C5orf24 Gene

Disorders for C5orf24 Gene

Relevant External Links for C5orf24

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C5orf24 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C5orf24 Gene

Publications for C5orf24 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 65
  3. Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. (PMID: 25609649) Li X. … Chen J. (Mol. Syst. Biol. 2015) 3 65
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 65
  5. System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability. (PMID: 25755297) Xiao Z. … Vertegaal A.C. (Mol. Cell. Proteomics 2015) 4 65

Products for C5orf24 Gene

Sources for C5orf24 Gene