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Aliases for C5orf15 Gene

Aliases for C5orf15 Gene

  • Chromosome 5 Open Reading Frame 15 2 3
  • Keratinocytes Associated Transmembrane Protein 2 2 3
  • KCT2 3 4
  • Keratinocyte-Associated Transmembrane Protein 2 3
  • HTGN29 3

External Ids for C5orf15 Gene

Summaries for C5orf15 Gene

GeneCards Summary for C5orf15 Gene

C5orf15 (Chromosome 5 Open Reading Frame 15) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C5orf15 Gene

Genomics for C5orf15 Gene

Genomic Location for C5orf15 Gene

Start:
133,955,502 bp from pter
End:
133,968,787 bp from pter
Size:
13,286 bases
Orientation:
Minus strand

Genomic View for C5orf15 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C5orf15 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C5orf15 Gene

Regulatory Elements for C5orf15 Gene

Proteins for C5orf15 Gene

  • Protein details for C5orf15 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NC54-KCT2_HUMAN
    Recommended name:
    Keratinocyte-associated transmembrane protein 2
    Protein Accession:
    Q8NC54
    Secondary Accessions:
    • B2RD10
    • D3DQ92
    • Q9NRG2

    Protein attributes for C5orf15 Gene

    Size:
    265 amino acids
    Molecular mass:
    29235 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C5orf15 Gene

Proteomics data for C5orf15 Gene at MOPED

Post-translational modifications for C5orf15 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C5orf15 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C5orf15 Gene

Domains for C5orf15 Gene

Protein Domains for C5orf15 Gene

ProtoNet:
genes like me logo Genes that share domains with C5orf15: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C5orf15 Gene

Function for C5orf15 Gene

miRNA for C5orf15 Gene

miRTarBase miRNAs that target C5orf15

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for C5orf15 Gene

Localization for C5orf15 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C5orf15 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C5orf15 Gene COMPARTMENTS Subcellular localization image for C5orf15 gene
Compartment Confidence
plasma membrane 2
endoplasmic reticulum 1
extracellular 1
nucleus 1

Gene Ontology (GO) - Cellular Components for C5orf15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C5orf15: view

Pathways for C5orf15 Gene

SuperPathways for C5orf15 Gene

No Data Available

Interacting Proteins for C5orf15 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000231512%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000385269%0d%0a
Selected Interacting proteins: ENSP00000231512 Q8NC54-KCT2_HUMAN for C5orf15 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for C5orf15 Gene

None

No data available for Pathways by source for C5orf15 Gene

Transcripts for C5orf15 Gene

mRNA/cDNA for C5orf15 Gene

Unigene Clusters for C5orf15 Gene

Chromosome 5 open reading frame 15:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C5orf15 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5
SP1:
SP2:
SP3: -
SP4: - -

Relevant External Links for C5orf15 Gene

GeneLoc Exon Structure for
C5orf15
ECgene alternative splicing isoforms for
C5orf15

Expression for C5orf15 Gene

mRNA expression in normal human tissues for C5orf15 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C5orf15 Gene

SOURCE GeneReport for Unigene cluster for C5orf15 Gene Hs.744034

mRNA Expression by UniProt/SwissProt for C5orf15 Gene

Q8NC54-KCT2_HUMAN
Tissue specificity: Widely expressed.
genes like me logo Genes that share expressions with C5orf15: view

Orthologs for C5orf15 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C5orf15 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C5H5orf15 36
  • 99.37 (n)
  • 99.25 (a)
C5orf15 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C7H5orf15 36
  • 83.59 (n)
  • 78.03 (a)
C7H5ORF15 37
  • 79 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C11H5orf15 36
  • 85.35 (n)
  • 79.55 (a)
C5orf15 37
  • 79 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 9530068E07Rik 36
  • 67.06 (n)
  • 62.75 (a)
9530068E07Rik 16
9530068E07Rik 37
  • 64 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C5orf15 37
  • 50 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C5orf15 37
  • 51 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1310352 36
  • 70.24 (n)
  • 66.67 (a)
chicken
(Gallus gallus)
Aves C13H5ORF15 36
  • 59.46 (n)
  • 51.92 (a)
C13H5ORF15 37
  • 29 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C5orf15 37
  • 26 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.14510 36
zebrafish
(Danio rerio)
Actinopterygii C21H5orf15 37
  • 15 (a)
OneToOne
Species with no ortholog for C5orf15:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C5orf15 Gene

ENSEMBL:
Gene Tree for C5orf15 (if available)
TreeFam:
Gene Tree for C5orf15 (if available)

Paralogs for C5orf15 Gene

Pseudogenes.org Pseudogenes for C5orf15 Gene

genes like me logo Genes that share paralogs with C5orf15: view

No data available for Paralogs for C5orf15 Gene

Variants for C5orf15 Gene

Sequence variations from dbSNP and Humsavar for C5orf15 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs10123 -- 133,955,631(-) TAGGG(A/G/T)AGGGA utr-variant-3-prime
rs10422 -- 133,955,951(-) TTTGT(A/G)TACAT utr-variant-3-prime
rs1801366 -- 133,955,940(-) AAAGG(A/G)TATTT utr-variant-3-prime
rs2112585 -- 133,967,372(-) TGCCA(A/G)CAGGG intron-variant
rs2279583 -- 133,970,527(-) TGAAG(G/T)GCACT upstream-variant-2KB

Relevant External Links for C5orf15 Gene

HapMap Linkage Disequilibrium report
C5orf15

No data available for Structural Variations from Database of Genomic Variants (DGV) for C5orf15 Gene

Disorders for C5orf15 Gene

Relevant External Links for C5orf15

Genetic Association Database (GAD)
C5orf15
genes like me logo Genes that share disorders with C5orf15: view

No data available for UniProtKB/Swiss-Prot for C5orf15 Gene

Publications for C5orf15 Gene

  1. Identification of novel genes for secreted and membrane-anchored proteins in human keratinocytes. (PMID: 12752121) Bonkobara M. … Ariizumi K. (Br. J. Dermatol. 2003) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. (PMID: 18951430) Anney R.J. … Gill M. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2008) 3 49
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3

Products for C5orf15 Gene

Sources for C5orf15 Gene

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