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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

C5AR2 Gene

protein-coding   GIFtS: 47
GCID: GC19P047841

Complement Component 5a Receptor 2

(Previous name: G protein-coupled receptor 77)
(Previous symbol: GPR77)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Complement Component 5a Receptor 21 2 3     C5a Anaphylatoxin Chemotactic Receptor 22
GPR771 2 3     C5a Anaphylatoxin Chemotactic Receptor C5L22
C5L22 3 5     G Protein-Coupled Receptor C5L22
G Protein-Coupled Receptor 771 2     G-Protein Coupled Receptor 773
GPF772 5     

External Ids:    HGNC: 45271   Entrez Gene: 272022   Ensembl: ENSG000001348307   OMIM: 6099495   UniProtKB: Q9P2963   

Export aliases for C5AR2 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for C5AR2 Gene:
This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate
immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with
intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may
alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the
pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Nov
2012)

GeneCards Summary for C5AR2 Gene: 
C5AR2 (complement component 5a receptor 2) is a protein-coding gene. Diseases associated with C5AR2 include familial combined hyperlipidemia, and familial mediterranean fever, and among its related super-pathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signaling. GO annotations related to this gene include protein binding and C5a anaphylatoxin receptor activity. An important paralog of this gene is LTB4R.

UniProtKB/Swiss-Prot: C5AR2_HUMAN, Q9P296
Function: Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their
dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling
pathways

Gene Wiki entry for C5AR2 (GPR77) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.2  NT_011109.16  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for C5AR2
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidC5AR2 promoter sequence
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Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C5AR2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.33   Ensembl cytogenetic band:  19q13.32   HGNC cytogenetic band: 19q13.33

C5AR2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C5AR2 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P047841:  view genomic region     (about GC identifiers)

Start:
47,835,404 bp from pter      End:
47,846,606 bp from pter
Size:
11,203 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: C5AR2_HUMAN, Q9P296 (See protein sequence)
Recommended Name: C5a anaphylatoxin chemotactic receptor 2  
Size: 337 amino acids; 36080 Da
Subunit: Interacts with C3 (the anaphylatoxin peptide C3a and the adipogenic hormone ASP); the interaction occurs
with higher affinity for ASP, enhancing the phosphorylation and activation of GPR77, recruitment of ARRB2 to the
cell surface and endocytosis of GRP77
Subcellular location: Cell membrane; Multi-pass membrane protein
Secondary accessions: B2RA09

Explore the universe of human proteins at neXtProt for C5AR2: NX_Q9P296

Explore proteomics data for C5AR2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9P296

  • C5AR2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    C5AR2 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001258678.1  NP_001258679.1  NP_060955.1  

    ENSEMBL proteins: 
     ENSP00000472620   ENSP00000471184   ENSP00000257267  
    Reactome Protein details: Q9P296
    Human Recombinant Protein Products for C5AR2: 
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    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005886plasma membrane TAS--
    GO:0009925basal plasma membrane IDA--
    GO:0016021integral to membrane IEA--
    GO:0045177apical part of cell IDA--

    C5AR2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CNAR: GPCR / Class A : Complement component receptors

    IUPHAR Guide to PHARMACOLOGY protein family classification: C5a2 receptor 
    Complement peptide receptors

    4 InterPro protein domains:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR000826 Formyl_pep_rcpt
     IPR001274 C5A_anaphtx_rcpt
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry Q9P296

    ProtoNet protein and cluster: Q9P296

    UniProtKB/Swiss-Prot: C5AR2_HUMAN, Q9P296
    Similarity: Belongs to the G-protein coupled receptor 1 family


    C5AR2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: C5AR2_HUMAN, Q9P296
    Function: Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their
    dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling
    pathways

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity ----
    GO:0004944C5a anaphylatoxin receptor activity IEA--
    GO:0004982N-formyl peptide receptor activity IEA--
    GO:0005515protein binding IPI12540846
         
    C5AR2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for C5AR2:
     Decreased Hepatitis C virus re 

         7 MGI mutant phenotypes (inferred from 2 alleles(MGI details for C5ar2):
     adipose tissue  behavior/neurological  cellular  homeostasis/metabolism  immune system 
     liver/biliary system  mortality/aging 

    C5AR2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out C5ar2tm1Cge for C5AR2

       inGenious Targeting Laboratory - Custom generated mouse model solutions for C5AR2 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for C5AR2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Class A/1 (Rhodopsin-like receptors)
    Class A/1 (Rhodopsin-like receptors)0.71
    Peptide ligand-binding receptors0.60
    GPCR ligand binding0.71
    GPCRs, Class A Rhodopsin-like0.41
    2Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.55
    3GPCRs, Other
    GPCRs, Other

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for C5AR2
        GPCRs, Other
    GPCRs, Class A Rhodopsin-like

    5        Reactome Pathways for C5AR2
        Peptide ligand-binding receptors
    Signal Transduction
    Signaling by GPCR
    GPCR ligand binding
    Class A/1 (Rhodopsin-like receptors)



    C5AR2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C5AR2

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/6 Interacting proteins for C5AR2 (Q9P2963 ENSP000002572674) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    C4AP0C0L43, ENSP000003966884I2D: score=1 STRING: ENSP00000396688
    ENSG00000206340P0C0L43I2D: score=1 
    ENSG00000227746P0C0L43I2D: score=1 
    C3P010243, ENSP000002459074I2D: score=1 STRING: ENSP00000245907
    C5AR1P217303, ENSP000003471974I2D: score=1 STRING: ENSP00000347197
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006935chemotaxis IEA--
    GO:0007186G-protein coupled receptor signaling pathway ----
    GO:0008150biological_process ND--
    GO:0032720negative regulation of tumor necrosis factor production IMP16204243
    GO:0090024negative regulation of neutrophil chemotaxis IMP16204243

    C5AR2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    C5AR2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for C5AR2

    4 IUPHAR Ligands for C5AR2 (C5a2 receptor)    About this table 
    LigandTypeActionAffinityPubmed IDs
    C5a des-Arg
    AgonistFull agonist8.64--
    C5a
    AgonistFull agonist8 - 8.611773063 12899627
    CHIPS-(28-149)
    AntagonistAntagonist6.617258808
    C5a hexapeptide analogue
    AgonistAgonist4.7412899627

    1 Novoseek inferred chemical compound relationship for C5AR2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    anaphylatoxin 88 6 11773063 (4), 20044484 (1), 11165367 (1)

    Search CenterWatch for drugs/clinical trials and news about C5AR2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for C5AR2 gene (3 alternative transcripts): 
    NM_001271749.1  NM_001271750.1  NM_018485.2  

    Unigene Cluster for C5AR2:

    Complement component 5a receptor 2
    Hs.534412  [show with all ESTs]
    Unigene Representative Sequence: NM_001271749
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000595464 ENST00000600626 ENST00000257267(uc021uwn.1)
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    Additional mRNA sequence: 

    AB038237.1 AK313994.1 BC067477.1 BC067478.1 BC067479.1 BC067480.1 

    2 DOTS entries:

    DT.101965936  DT.121442175 

    10 AceView cDNA sequences:

    NM_018485 AB038237 CD246159 BC067480 CF147796 BC067477 BC067478 BP370117 
    CA405648 BC067479 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    C5AR2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    C5AR2 Expression
    About this image


    See C5AR2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for C5AR2

    SOURCE GeneReport for Unigene cluster: Hs.534412

    UniProtKB/Swiss-Prot: C5AR2_HUMAN, Q9P296
    Tissue specificity: Frontal cortex, hippocampus, hypothalamus, pons and liver

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for C5AR2 gene from 4/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia C5ar25
    Gpr771
    G protein-coupled receptor 771, 5 68.69(n)1
    61.21(a)1
      7 (8.77 cM)5
    3194301  NM_001146005.11  NP_001139477.11 
     162345855 
    chicken
    (Gallus gallus)
    Aves C5AR16
    Uncharacterized protein
    36(a)
    1 → many
    AADN03021485.1(3036-4109)
    lizard
    (Anolis carolinensis)
    Reptilia C5AR16
    Uncharacterized protein
    34(a)
    1 → many
    LGf(1670852-1671922)
    zebrafish
    (Danio rerio)
    Actinopterygii C5AR16
    C5a anaphylatoxin chemotactic receptor
    30(a)
    1 → many
    18(45207298-45208338)


    ENSEMBL Gene Tree for C5AR2 (if available)
    TreeFam Gene Tree for C5AR2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for C5AR2 gene
    LTB4R2  LTB4R22  GPR332  FPR32  FPR12  C5AR12  GPR322  GPR1522  
    FPR22  C3AR12  PTGDR22  GPR12  CMKLR12  
    7 SIMAP similar genes for C5AR2 using alignment to 1 protein entry:     C5AR2_HUMAN:
    GPR77    C5AR1    PTGDR2    CMKLR1    FPR1    gpcr
    FPR2

    C5AR2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/312 SNPs in C5AR2 are shown (see all 312)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs112986831,2
    C--47833446(+) TACTC-/GGGGGG 1 -- us2k11Minor allele frequency- G:0.00NA 2
    rs65093191,2
    C--47833479(+) aacccA/Gggagg 1 -- us2k15Minor allele frequency- G:0.00NA WA 10
    rs112986841,2
    C--47833554(+) GTCTC-/AAAAAA 1 -- us2k12Minor allele frequency- A:0.00NA CSA 4
    rs1828055271,2
    --47833650(+) AGGCCA/GGGGCA 1 -- us2k10--------
    rs1156056351,2
    F--47833733(+) GGAGGG/CGAGGG 1 -- us2k11Minor allele frequency- C:0.02WA 118
    rs1477320121,2
    --47833790(+) CCAACG/TCAGGG 1 -- us2k10--------
    rs1161611481,2
    F--47833864(+) TCTCAC/AGAACA 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1866252531,2
    --47833865(+) CTCACA/GAACAA 1 -- us2k10--------
    rs730633881,2
    C,F--47834105(+) TACTAT/GGTGCC 1 -- us2k11Minor allele frequency- G:0.15NA 120
    rs1910795831,2
    --47834134(+) TTTGTC/TTTTGT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for C5AR2 (47835404 - 47846606 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for C5AR2: --
    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing C5AR2
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609949    OMIM disorders: --

    4 diseases for C5AR2:    About MalaCards
    familial combined hyperlipidemia    familial mediterranean fever    insulin resistance    diabetes mellitus


    C5AR2 for disorders           About GeneDecksing

    2 Novoseek inferred disease relationships for C5AR2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    necrosis 0 2 17464341 (2)
    tumors 0 2 17464341 (2)


    Export disorders for C5AR2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for C5AR2 gene, integrated from 9 sources (see all 48):
    (articles sorted by number of sources associating them with C5AR2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of four novel human G protein-coupled receptors expressed in the brain. (PubMed id 11165367)1, 2, 3, 9 Lee D.K.... O'Dowd B.F. (2001)
    2. The chemoattractant receptor-like protein C5L2 binds the C3a des-Arg77/acylation-stimulating protein. (PubMed id 12540846)1, 2, 9 Kalant D....Monk P.N. (2003)
    3. The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des Arg(74). (PubMed id 11773063)1, 2, 9 Cain S.A. and Monk P.N. (2002)
    4. A putative chemoattractant receptor, C5L2, is expressed in granulocyte and immature dendritic cells, but not in mature dendritic cells. (PubMed id 11090875)1, 2, 9 Ohno M....Takahashi T.A. (2000)
    5. Relationship between a novel polymorphism of the C5L2 gene and coronary artery disease. (PubMed id 21698200)1, 2 Zheng Y.Y....Liu F. (2011)
    6. C5a- and ASP-mediated C5L2 activation, endocytosis an d recycling are lost in S323I-C5L2 mutation. (PubMed id 19615750)1, 2 Cui W....Cianflone K. (2009)
    7. C5L2 is a functional receptor for acylation-stimulating protein. (PubMed id 15833747)1, 2 Kalant D....Cianflone K. (2005)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. The human complement fragment receptor, C5L2, is a recycling decoy receptor. (PubMed id 19100624)1, 9 Scola A.M....Monk P.N. (2009)
    10. The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand binding. (PubMed id 17158873)1, 9 Scola A.M....Monk P.N. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 27202 HGNC: 4527 AceView: GPR77 Ensembl:ENSG00000134830 euGenes: HUgn27202
    ECgene: C5AR2 H-InvDB: C5AR2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for C5AR2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for C5AR2 gene:
    Search GeneIP for patents involving C5AR2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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