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Aliases for C4orf51 Gene

Aliases for C4orf51 Gene

  • Chromosome 4 Open Reading Frame 51 2 3 5

External Ids for C4orf51 Gene

Previous GeneCards Identifiers for C4orf51 Gene

  • GC04P146821
  • GC04P146601
  • GC04P142331

Summaries for C4orf51 Gene

GeneCards Summary for C4orf51 Gene

C4orf51 (Chromosome 4 Open Reading Frame 51) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C4orf51 Gene

Genomics for C4orf51 Gene

Regulatory Elements for C4orf51 Gene

Enhancers for C4orf51 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04G145803 1.9 FANTOM5 Ensembl ENCODE dbSUPER 10.1 +126.8 126776 6.9 HDGF PKNOX1 FOXA2 FEZF1 ETS1 TCF12 GLIS2 GATA2 ZNF207 FOS ENSG00000251687 C4orf51 ZNF827 ENSG00000279481 GC04M145759
GH04G145715 1.2 ENCODE dbSUPER 11.3 +36.4 36411 1.9 ZSCAN4 ZNF76 RAD21 ZSCAN9 ZNF48 RARA ZEB1 ZNF335 SLC30A9 GLIS2 C4orf51 GC04M145759
GH04G145709 0.6 ENCODE 11.3 +29.9 29945 0.9 JUND RFX1 BHLHE40 MNT FOS NFE2L2 C4orf51 MMAA GC04M145759
GH04G145703 0.5 ENCODE 11.8 +24.5 24541 2.4 CTBP1 POU5F1 DPF2 C4orf51 MMAA GC04M145759
GH04G145625 0.5 FANTOM5 10.6 -54.2 -54190 0.3 POLR2A NR2F1 TBX21 ENSG00000248356 C4orf51 ZNF827 NCOA4P3 MMAA
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C4orf51 on UCSC Golden Path with GeneCards custom track

Genomic Location for C4orf51 Gene

Chromosome:
4
Start:
145,680,104 bp from pter
End:
145,800,392 bp from pter
Size:
120,289 bases
Orientation:
Plus strand

Genomic View for C4orf51 Gene

Genes around C4orf51 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C4orf51 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C4orf51 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C4orf51 Gene

Proteins for C4orf51 Gene

  • Protein details for C4orf51 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    C9J302-CD051_HUMAN
    Recommended name:
    Uncharacterized protein C4orf51
    Protein Accession:
    C9J302

    Protein attributes for C4orf51 Gene

    Size:
    202 amino acids
    Molecular mass:
    23001 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C4orf51 Gene

Post-translational modifications for C4orf51 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C4orf51 Gene

Domains & Families for C4orf51 Gene

Protein Domains for C4orf51 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C4orf51: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C4orf51 Gene

Function for C4orf51 Gene

Phenotypes for C4orf51 Gene

GenomeRNAi human phenotypes for C4orf51:
genes like me logo Genes that share phenotypes with C4orf51: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C4orf51 Gene

Localization for C4orf51 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C4orf51 gene
Compartment Confidence
extracellular 3
nucleus 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C4orf51 Gene

Pathways & Interactions for C4orf51 Gene

SuperPathways for C4orf51 Gene

No Data Available

Interacting Proteins for C4orf51 Gene

Gene Ontology (GO) - Biological Process for C4orf51 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C4orf51 Gene

Drugs & Compounds for C4orf51 Gene

No Compound Related Data Available

Transcripts for C4orf51 Gene

mRNA/cDNA for C4orf51 Gene

(14) REFSEQ mRNAs :
(0) Additional mRNA sequences :
-
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C4orf51 Gene

Chromosome 4 open reading frame 51:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for C4orf51 Gene

No ASD Table

Relevant External Links for C4orf51 Gene

GeneLoc Exon Structure for
C4orf51
ECgene alternative splicing isoforms for
C4orf51

Expression for C4orf51 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C4orf51 Gene

mRNA differential expression in normal tissues according to GTEx for C4orf51 Gene

This gene is overexpressed in Testis (x50.7).

NURSA nuclear receptor signaling pathways regulating expression of C4orf51 Gene:

C4orf51

SOURCE GeneReport for Unigene cluster for C4orf51 Gene:

Hs.452865
genes like me logo Genes that share expression patterns with C4orf51: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C4orf51 Gene

Orthologs for C4orf51 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C4orf51 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C4H4orf51 34
  • 99.67 (n)
C4orf51 35
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C17H4orf51 34
  • 76.67 (n)
mouse
(Mus musculus)
Mammalia 1700011L22Rik 34 16 35
  • 70.05 (n)
rat
(Rattus norvegicus)
Mammalia LOC498933 34
  • 64.18 (n)
Species where no ortholog for C4orf51 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C4orf51 Gene

ENSEMBL:
Gene Tree for C4orf51 (if available)
TreeFam:
Gene Tree for C4orf51 (if available)

Paralogs for C4orf51 Gene

No data available for Paralogs for C4orf51 Gene

Variants for C4orf51 Gene

Sequence variations from dbSNP and Humsavar for C4orf51 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1000000468 -- 145,684,550(+) AATGA(C/G)ATAAC intron-variant
rs1000044127 -- 145,733,286(+) CACAG(-/GCCGCCTCC)GCCGC intron-variant, downstream-variant-500B
rs1000052122 -- 145,694,833(+) AAACA(C/G)CTCCC intron-variant
rs1000081356 -- 145,788,223(+) TATCG(C/T)AAAGA intron-variant
rs1000093514 -- 145,684,873(+) AAGGA(A/G)AGACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C4orf51 Gene

Variant ID Type Subtype PubMed ID
esv3303041 CNV tandem duplication 20981092
esv3368860 OTHER inversion 20981092
esv3388375 OTHER inversion 20981092
esv5587 CNV gain 19470904
nsv1143106 CNV tandem duplication 24896259
nsv830105 CNV loss 17160897

Variation tolerance for C4orf51 Gene

Residual Variation Intolerance Score: 71.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.47; 64.25% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C4orf51 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C4orf51

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C4orf51 Gene

Disorders for C4orf51 Gene

Relevant External Links for C4orf51

Genetic Association Database (GAD)
C4orf51
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C4orf51

No disorders were found for C4orf51 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C4orf51 Gene

Publications for C4orf51 Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4 64

Products for C4orf51 Gene

Sources for C4orf51 Gene

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