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Aliases for C4orf36 Gene

Aliases for C4orf36 Gene

  • Chromosome 4 Open Reading Frame 36 2 3 5

External Ids for C4orf36 Gene

Previous GeneCards Identifiers for C4orf36 Gene

  • GC04M088016
  • GC04M087797
  • GC04M083543

Summaries for C4orf36 Gene

GeneCards Summary for C4orf36 Gene

C4orf36 (Chromosome 4 Open Reading Frame 36) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C4orf36 Gene

Genomics for C4orf36 Gene

Regulatory Elements for C4orf36 Gene

Enhancers for C4orf36 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around C4orf36 on UCSC Golden Path with GeneCards custom track

Promoters for C4orf36 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for C4orf36 Gene

86,876,205 bp from pter
86,936,202 bp from pter
59,998 bases
Minus strand

Genomic View for C4orf36 Gene

Genes around C4orf36 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C4orf36 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C4orf36 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C4orf36 Gene

Proteins for C4orf36 Gene

  • Protein details for C4orf36 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C4orf36
    Protein Accession:

    Protein attributes for C4orf36 Gene

    117 amino acids
    Molecular mass:
    13276 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C4orf36 Gene

Post-translational modifications for C4orf36 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C4orf36 Gene

No data available for DME Specific Peptides for C4orf36 Gene

Domains & Families for C4orf36 Gene

Protein Domains for C4orf36 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C4orf36: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C4orf36 Gene

Function for C4orf36 Gene

genes like me logo Genes that share phenotypes with C4orf36: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C4orf36 Gene

Localization for C4orf36 Gene

Subcellular locations from

Jensen Localization Image for C4orf36 Gene COMPARTMENTS Subcellular localization image for C4orf36 gene
Compartment Confidence
extracellular 2
mitochondrion 2
cytosol 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C4orf36 Gene

Pathways & Interactions for C4orf36 Gene

SuperPathways for C4orf36 Gene

No Data Available

Interacting Proteins for C4orf36 Gene

Gene Ontology (GO) - Biological Process for C4orf36 Gene


No data available for Pathways by source and SIGNOR curated interactions for C4orf36 Gene

Drugs & Compounds for C4orf36 Gene

No Compound Related Data Available

Transcripts for C4orf36 Gene

Unigene Clusters for C4orf36 Gene

Chromosome 4 open reading frame 36:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C4orf36 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b ^ 6
SP1: - - -
SP2: -
SP3: - - -
SP4: - -

Relevant External Links for C4orf36 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C4orf36 Gene

mRNA expression in normal human tissues for C4orf36 Gene

Protein differential expression in normal tissues from HIPED for C4orf36 Gene

This gene is overexpressed in Uterus (8.3), Spleen (6.7), and Retina (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C4orf36 Gene

Protein tissue co-expression partners for C4orf36 Gene

NURSA nuclear receptor signaling pathways regulating expression of C4orf36 Gene:


SOURCE GeneReport for Unigene cluster for C4orf36 Gene:

genes like me logo Genes that share expression patterns with C4orf36: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C4orf36 Gene

Orthologs for C4orf36 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C4orf36 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C6H4orf36 34
  • 81.77 (n)
  • 73.5 (a)
(Mus musculus)
Mammalia 1700016H13Rik 34
  • 71.79 (n)
  • 64.1 (a)
1700016H13Rik 16
1700016H13Rik 35
  • 63 (a)
(Pan troglodytes)
Mammalia C4H4orf36 34
  • 98.86 (n)
  • 100 (a)
C4orf36 35
  • 99 (a)
(Rattus norvegicus)
Mammalia LOC498330 34
  • 70.94 (n)
  • 59.83 (a)
(Canis familiaris)
Mammalia C4orf36 35
  • 74 (a)
(Monodelphis domestica)
Mammalia C4orf36 35
  • 52 (a)
(Ornithorhynchus anatinus)
Mammalia C4orf36 35
  • 34 (a)
Species where no ortholog for C4orf36 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C4orf36 Gene

Gene Tree for C4orf36 (if available)
Gene Tree for C4orf36 (if available)

Paralogs for C4orf36 Gene

No data available for Paralogs for C4orf36 Gene

Variants for C4orf36 Gene

Sequence variations from dbSNP and Humsavar for C4orf36 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1550931 - 86,888,234(+) TTGTG(C/G/T)ACCAG reference, missense
rs11938345 - 86,891,468(+) AACAA(C/T)TGCCC reference, missense
rs1374934 -- 86,877,043(-) AGGGT(C/T)ACTGT intron-variant
rs1374935 -- 86,876,708(-) ATAGT(A/G)AAGAT intron-variant
rs1010902 -- 86,898,002(+) TACAA(C/T)GTCAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C4orf36 Gene

Variant ID Type Subtype PubMed ID
nsv1013308 CNV gain 25217958
nsv508297 CNV deletion 20534489
nsv594787 CNV gain 21841781
nsv967771 CNV duplication 23825009

Variation tolerance for C4orf36 Gene

Residual Variation Intolerance Score: 82.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.50; 77.61% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C4orf36 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C4orf36 Gene

Disorders for C4orf36 Gene

Relevant External Links for C4orf36

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C4orf36 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C4orf36 Gene

Publications for C4orf36 Gene

  1. A high-density genome-wide association screen of sporadic ALS in US veterans. (PMID: 22470424) Kwee L.C. … Hauser M.A. (PLoS ONE 2012) 3 46 65
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 65
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 65
  5. Genetic variants associated with disordered eating. (PMID: 23568457) Wade T.D. … Martin N.G. (Int J Eat Disord 2013) 3 65

Products for C4orf36 Gene

Sources for C4orf36 Gene

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