C4orf36 Gene
protein-coding GIFtS: 38
GCID: GC04M087797
|
|
chromosome 4 open reading frame 36
| |
Aliases
for C4orf36 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 4 Open Reading Frame 361 2 | | MGC267441 | | Uncharacterized Protein C4orf362 |
Export aliases for C4orf36 gene to outside databasesPrevious GC identifers: GC04M088016 GC04M083543 |
Summaries
for C4orf36 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C4orf36 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C4orf36 gene promoter:
S8 p53 POU2F1 POU2F1a Chx10 CUTL1 E4BP4 YY1
Other transcription factors
Search SABiosciences Chromatin IP Primers for C4orf36
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C4orf36 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q21.3 Ensembl cytogenetic band: 4q21.3 HGNC cytogenetic band: 4q21.3C4orf36 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M087797: view genomic region
(about GC identifiers)
Start:
|
87,797,358 bp from pter |
End:
|
87,857,354 bp from pter |
Size:
|
59,997 bases |
Orientation:
|
minus strand |
|
Proteins
for C4orf36 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CD036_HUMAN, Q96KX1 (See
protein sequence)Recommended Name: Uncharacterized protein C4orf36 Size: 117 amino acids; 13276 DaExplore the universe of human proteins at neXtProt for C4orf36: NX_Q96KX1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96KX1
C4orf36 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_653246.1
ENSEMBL proteins: ENSP00000295898 ENSP00000420949 ENSP00000421568 ENSP00000421141 ENSP00000427122 ENSP00000422720 ENSP00000425771 ENSP00000420899
Human Recombinant Protein Products:
C4orf36 Antibody Products:
Assay Products for C4orf36: |
Protein
Domains /
Families
for C4orf36 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q96KX1 |
Function
for C4orf36 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C4orf36 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C4orf36
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C4orf36 (NM_144645) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C4orf36 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C4orf36 |
1 GenomeRNAi human phenotype for C4orf36:
|
Pathways & Interactions
for C4orf36 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C4orf36
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for C4orf36 (ENSP000002958984) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for C4orf36 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C4orf36
Search CenterWatch for drugs/clinical trials and news about C4orf36 / CD036
|
Transcripts
for C4orf36 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C4orf36 gene: NM_144645.3 Unigene Cluster for C4orf36: Chromosome 4 open reading frame 36 Hs.339646 [show with all ESTs]Unigene Representative Sequence: BQ21514812 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000295898(uc003hqe.4) ENST00000473559 ENST00000462714 ENST00000506308
ENST00000512468 ENST00000504008 ENST00000503001 ENST00000504371 ENST00000508280(uc003hqf.1)
ENST00000506484 ENST00000509262 ENST00000503159
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C4orf36 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C4orf36
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C4orf36 (NM_144645) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C4orf36 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C4orf36 |
Additional cDNA sequence: BC016746.1 4 DOTS entries: DT.40131930 DT.95335326 DT.121271687 DT.121271694 24/60 AceView cDNA sequences (see all 60): BU622986 CR607080 BU790343 AA700107 CR613732 BU790044 CD364809 AI990364 AL711278 BF792739 BX360317 BI767656 BI559460 BG721311 BX104678 CK823693 BM978572 AI066579 AA203516 NM_144645 BX090513 BX356037 BM510359 BG656274
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for C4orf36 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6 |
|---|
|
| SP1: | | | - | | - | | | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | | | | | | | | | - | | | | |
| SP4: | | | | | | | | | | | - | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for C4orf36
|
Expression
for C4orf36 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C4orf36 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCGTATGGAG
About this image
See C4orf36 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C4orf36
SOURCE GeneReport for Unigene cluster: Hs.339646
SABiosciences Custom PCR Arrays for C4orf36
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C4orf36
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C4orf36 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C4orf36 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C4orf36 |
Orthologs
for C4orf36 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for C4orf36 gene from 1/7 species (see all 7) About this table
ENSEMBL Gene Tree for C4orf36 (if available)
TreeFam Gene Tree for C4orf36 (if available) |
Paralogs
for C4orf36 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C4orf36 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C4orf36 |
|
Disorders
/ Diseases
for C4orf36 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 C4orf36 for disorders About MalaCards
C4orf36 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: C4orf36 (1 document)
Export disorders for C4orf36 gene to outside databases
|
Publications
for C4orf36 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C4orf36 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C4orf36) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)1 Emanuele M.J....Elledge S.J. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
|
External Searches for C4orf36 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C4orf36 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C4orf36 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C4orf36 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C4orf36 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C4orf36 gene:
Search GeneIP for patents involving C4orf36
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C4orf36 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C4orf36 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C4orf36 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C4orf36 | | | OriGene Protein Over-expression Lysate for C4orf36 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C4orf36 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C4orf36 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C4orf36 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C4orf36 | | OriGene Custom Protein Services for C4orf36 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C4orf36 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C4orf36 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C4orf36 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C4orf36 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C4orf36 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C4orf36 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for C4orf36 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | C4orf36 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for C4orf36 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C4orf36 |
|
|
|
|
