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Aliases for C4orf33 Gene

Aliases for C4orf33 Gene

  • Chromosome 4 Open Reading Frame 33 2 3

External Ids for C4orf33 Gene

Previous GeneCards Identifiers for C4orf33 Gene

  • GC04P130234
  • GC04P130014
  • GC04P125745

Summaries for C4orf33 Gene

GeneCards Summary for C4orf33 Gene

C4orf33 (Chromosome 4 Open Reading Frame 33) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C4orf33 Gene

Genomics for C4orf33 Gene

Regulatory Elements for C4orf33 Gene

Transcription factor binding sites by QIAGEN in the C4orf33 gene promoter:

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C4orf33 Gene

Start:
129,093,317 bp from pter
End:
129,116,640 bp from pter
Size:
23,324 bases
Orientation:
Plus strand

Genomic View for C4orf33 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C4orf33 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C4orf33 Gene

Proteins for C4orf33 Gene

  • Protein details for C4orf33 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N1A6-CD033_HUMAN
    Recommended name:
    UPF0462 protein C4orf33
    Protein Accession:
    Q8N1A6
    Secondary Accessions:
    • D3DNY2
    • Q6PJF3
    • Q8NBC5

    Protein attributes for C4orf33 Gene

    Size:
    199 amino acids
    Molecular mass:
    23468 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C4orf33 Gene

Proteomics data for C4orf33 Gene at MOPED

Post-translational modifications for C4orf33 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C4orf33 Gene

No data available for DME Specific Peptides for C4orf33 Gene

Domains for C4orf33 Gene

Protein Domains for C4orf33 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C4orf33 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N1A6

UniProtKB/Swiss-Prot:

CD033_HUMAN :
  • Q8N1A6
Family:
  • Belongs to the UPF0462 family.
genes like me logo Genes that share domains with C4orf33: view

No data available for Gene Families for C4orf33 Gene

Function for C4orf33 Gene

Gene Ontology (GO) - Molecular Function for C4orf33 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C4orf33: view

Phenotypes for C4orf33 Gene

genes like me logo Genes that share phenotypes with C4orf33: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C4orf33 Gene

Localization for C4orf33 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C4orf33 Gene COMPARTMENTS Subcellular localization image for C4orf33 gene
Compartment Confidence
cytosol 3
nucleus 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C4orf33 Gene

Pathways for C4orf33 Gene

SuperPathways for C4orf33 Gene

No Data Available

Interacting Proteins for C4orf33 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000281146%0d%0a9606.ENSP00000166345%0d%0a9606.ENSP00000261776%0d%0a
Selected Interacting proteins: ENSP00000281146 Q8N1A6-CD033_HUMAN for C4orf33 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for C4orf33 Gene

None

No data available for Pathways by source for C4orf33 Gene

Transcripts for C4orf33 Gene

Unigene Clusters for C4orf33 Gene

Chromosome 4 open reading frame 33:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C4orf33

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C4orf33 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b · 9c
SP1: - - - - - -
SP2: - - - -
SP3: - -
SP4:
SP5:

Relevant External Links for C4orf33 Gene

GeneLoc Exon Structure for
C4orf33
ECgene alternative splicing isoforms for
C4orf33

Expression for C4orf33 Gene

mRNA expression in normal human tissues for C4orf33 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C4orf33 Gene

SOURCE GeneReport for Unigene cluster for C4orf33 Gene Hs.567679

genes like me logo Genes that share expressions with C4orf33: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C4orf33 Gene

Orthologs for C4orf33 Gene

This gene was present in the common ancestor of animals.

Orthologs for C4orf33 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C4H4orf33 35
  • 98.83 (n)
  • 97.99 (a)
C4orf33 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C17H4orf33 35
  • 91.79 (n)
  • 89.45 (a)
C4orf33 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C19H4orf33 35
  • 90.62 (n)
  • 86.43 (a)
C4orf33 36
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia D3Ertd751e 35
  • 85.24 (n)
  • 82.29 (a)
D3Ertd751e 16
D3Ertd751e 36
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C4orf33 36
  • 52 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C4orf33 36
  • 60 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1359508 35
  • 87.27 (n)
  • 83.42 (a)
chicken
(Gallus gallus)
Aves C4ORF33 35
  • 73.44 (n)
  • 69.79 (a)
C4orf33 36
  • 66 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C4orf33 36
  • 70 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c4orf33 35
  • 67.7 (n)
  • 68.04 (a)
Str.17636 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.11064 35
zebrafish
(Danio rerio)
Actinopterygii C1H4orf33 36
  • 61 (a)
OneToOne
zgc:77739 35
  • 61.73 (n)
  • 60.71 (a)
worm
(Caenorhabditis elegans)
Secernentea C33A12.3 36
  • 36 (a)
OneToOne
CELE_C33A12.3 35
  • 54.73 (n)
  • 46.59 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 48 (a)
OneToOne
Species with no ortholog for C4orf33:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for C4orf33 Gene

ENSEMBL:
Gene Tree for C4orf33 (if available)
TreeFam:
Gene Tree for C4orf33 (if available)

Paralogs for C4orf33 Gene

Selected SIMAP similar genes for C4orf33 Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for C4orf33 Gene

genes like me logo Genes that share paralogs with C4orf33: view

No data available for Paralogs for C4orf33 Gene

Variants for C4orf33 Gene

Sequence variations from dbSNP and Humsavar for C4orf33 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs3790 -- 129,112,535(-) GATCA(A/G)AATAC utr-variant-3-prime
rs189236 -- 129,107,257(-) AGAGA(A/G)TCCAA intron-variant
rs337263 -- 129,112,510(-) ACCCC(A/G)GAAAA utr-variant-3-prime
rs337276 -- 129,109,789(-) TACTA(G/T)ATACT intron-variant
rs337277 - 129,109,497(-) GGACA(C/T)TCTGA reference, missense

Structural Variations from Database of Genomic Variants (DGV) for C4orf33 Gene

Variant ID Type Subtype PubMed ID
nsv879931 CNV Loss 21882294

Relevant External Links for C4orf33 Gene

HapMap Linkage Disequilibrium report
C4orf33

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C4orf33 Gene

Disorders for C4orf33 Gene

Relevant External Links for C4orf33

Genetic Association Database (GAD)
C4orf33
Human Genome Epidemiology (HuGE) Navigator
C4orf33
genes like me logo Genes that share disorders with C4orf33: view

No data available for UniProtKB/Swiss-Prot for C4orf33 Gene

Publications for C4orf33 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Distinct class of putative "non-conserved" promoters in humans: comparative studies of alternative promoters of human and mouse genes. (PMID: 17567985) Tsuritani K. … Suzuki Y. (Genome Res. 2007) 3
  4. Identification of host proteins required for HIV infection through a functional genomic screen. (PMID: 18187620) Brass A.L. … Elledge S.J. (Science 2008) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for C4orf33 Gene

Sources for C4orf33 Gene

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