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Aliases for C4orf33 Gene

Aliases for C4orf33 Gene

  • Chromosome 4 Open Reading Frame 33 2 3 5

External Ids for C4orf33 Gene

Previous GeneCards Identifiers for C4orf33 Gene

  • GC04P130234
  • GC04P130014
  • GC04P125745

Summaries for C4orf33 Gene

GeneCards Summary for C4orf33 Gene

C4orf33 (Chromosome 4 Open Reading Frame 33) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C4orf33 Gene

Genomics for C4orf33 Gene

Regulatory Elements for C4orf33 Gene

Promoters for C4orf33 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C4orf33 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the C4orf33 gene promoter:

Genomic Location for C4orf33 Gene

129,093,317 bp from pter
129,116,640 bp from pter
23,324 bases
Plus strand

Genomic View for C4orf33 Gene

Genes around C4orf33 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C4orf33 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C4orf33 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C4orf33 Gene

Proteins for C4orf33 Gene

  • Protein details for C4orf33 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UPF0462 protein C4orf33
    Protein Accession:
    Secondary Accessions:
    • D3DNY2
    • Q6PJF3
    • Q8NBC5

    Protein attributes for C4orf33 Gene

    199 amino acids
    Molecular mass:
    23468 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C4orf33 Gene

Proteomics data for C4orf33 Gene at MOPED

Post-translational modifications for C4orf33 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C4orf33 Gene

No data available for DME Specific Peptides for C4orf33 Gene

Domains & Families for C4orf33 Gene

Protein Domains for C4orf33 Gene


Suggested Antigen Peptide Sequences for C4orf33 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the UPF0462 family.
  • Belongs to the UPF0462 family.
genes like me logo Genes that share domains with C4orf33: view

No data available for Gene Families for C4orf33 Gene

Function for C4orf33 Gene

genes like me logo Genes that share phenotypes with C4orf33: view

Animal Model Products

CRISPR Products

miRNA for C4orf33 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C4orf33 Gene

Localization for C4orf33 Gene

Subcellular locations from

Jensen Localization Image for C4orf33 Gene COMPARTMENTS Subcellular localization image for C4orf33 gene
Compartment Confidence
cytosol 3
nucleus 3
golgi apparatus 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C4orf33 Gene

Pathways & Interactions for C4orf33 Gene

SuperPathways for C4orf33 Gene

No Data Available

Interacting Proteins for C4orf33 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: Q8N1A6-CD033_HUMAN ENSP00000281146 for C4orf33 Gene via UniProtKB STRING

Gene Ontology (GO) - Biological Process for C4orf33 Gene


No data available for Pathways by source and SIGNOR curated interactions for C4orf33 Gene

Drugs & Compounds for C4orf33 Gene

No Compound Related Data Available

Transcripts for C4orf33 Gene

Unigene Clusters for C4orf33 Gene

Chromosome 4 open reading frame 33:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C4orf33 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b · 9c
SP1: - - - - - -
SP2: - - - -
SP3: - -

Relevant External Links for C4orf33 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C4orf33 Gene

mRNA expression in normal human tissues for C4orf33 Gene

Protein differential expression in normal tissues from HIPED for C4orf33 Gene

This gene is overexpressed in Oral epithelium (17.1), Spleen (13.4), Platelet (8.6), Pancreas (7.6), and Skin (6.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for C4orf33 Gene

SOURCE GeneReport for Unigene cluster for C4orf33 Gene Hs.567679

genes like me logo Genes that share expression patterns with C4orf33: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C4orf33 Gene

Orthologs for C4orf33 Gene

This gene was present in the common ancestor of animals.

Orthologs for C4orf33 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C17H4orf33 35
  • 91.79 (n)
  • 89.45 (a)
C4orf33 36
  • 89 (a)
(Canis familiaris)
Mammalia C19H4orf33 35
  • 90.62 (n)
  • 86.43 (a)
C4orf33 36
  • 84 (a)
(Mus musculus)
Mammalia D3Ertd751e 35
  • 85.24 (n)
  • 82.29 (a)
D3Ertd751e 16
D3Ertd751e 36
  • 82 (a)
(Pan troglodytes)
Mammalia C4H4orf33 35
  • 98.83 (n)
  • 97.99 (a)
C4orf33 36
  • 98 (a)
(Rattus norvegicus)
Mammalia RGD1359508 35
  • 87.27 (n)
  • 83.42 (a)
(Monodelphis domestica)
Mammalia C4orf33 36
  • 52 (a)
(Ornithorhynchus anatinus)
Mammalia C4orf33 36
  • 60 (a)
(Gallus gallus)
Aves C4ORF33 35
  • 73.44 (n)
  • 69.79 (a)
C4orf33 36
  • 66 (a)
(Anolis carolinensis)
Reptilia C4orf33 36
  • 70 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c4orf33 35
  • 67.7 (n)
  • 68.04 (a)
Str.17636 35
(Danio rerio)
Actinopterygii zgc:77739 35
  • 61.73 (n)
  • 60.71 (a)
C1H4orf33 36
  • 61 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.11064 35
(Caenorhabditis elegans)
Secernentea CELE_C33A12.3 35
  • 54.73 (n)
  • 46.59 (a)
C33A12.3 36
  • 36 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 48 (a)
Species with no ortholog for C4orf33:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for C4orf33 Gene

Gene Tree for C4orf33 (if available)
Gene Tree for C4orf33 (if available)

Paralogs for C4orf33 Gene

(1) SIMAP similar genes for C4orf33 Gene using alignment to 4 proteins: Pseudogenes for C4orf33 Gene

genes like me logo Genes that share paralogs with C4orf33: view

No data available for Paralogs for C4orf33 Gene

Variants for C4orf33 Gene

Sequence variations from dbSNP and Humsavar for C4orf33 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs35199409 - 129,102,729(-) GATCC(A/C)TGAAA nc-transcript-variant, reference, missense
rs2271570 - 129,109,489(+) TTTAT(C/T)GTTCA nc-transcript-variant, reference, missense
rs337277 - 129,109,497(-) GGACA(C/T)TCTGA nc-transcript-variant, reference, missense
rs17351999 - 129,111,688(+) TAGCC(A/G)TTGCC nc-transcript-variant, reference, missense
rs3790 -- 129,112,535(-) GATCA(A/G)AATAC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for C4orf33 Gene

Variant ID Type Subtype PubMed ID
nsv879931 CNV Loss 21882294

Variation tolerance for C4orf33 Gene

Residual Variation Intolerance Score: 81.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.78; 91.64% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C4orf33 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C4orf33 Gene

Disorders for C4orf33 Gene

Relevant External Links for C4orf33

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C4orf33 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C4orf33 Gene

Publications for C4orf33 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. Identification of host proteins required for HIV infection through a functional genomic screen. (PMID: 18187620) Brass A.L. … Elledge S.J. (Science 2008) 3

Products for C4orf33 Gene

Sources for C4orf33 Gene

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