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Aliases for C4orf32 Gene

Aliases for C4orf32 Gene

  • Chromosome 4 Open Reading Frame 32 2 3

External Ids for C4orf32 Gene

Previous GeneCards Identifiers for C4orf32 Gene

  • GC04P113286
  • GC04P113066
  • GC04P108798

Summaries for C4orf32 Gene

GeneCards Summary for C4orf32 Gene

C4orf32 (Chromosome 4 Open Reading Frame 32) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C4orf32 Gene

Genomics for C4orf32 Gene

Regulatory Elements for C4orf32 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C4orf32 Gene

Chromosome:
4
Start:
112,145,397 bp from pter
End:
112,195,256 bp from pter
Size:
49,860 bases
Orientation:
Plus strand

Genomic View for C4orf32 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for C4orf32 Gene

Proteins for C4orf32 Gene

  • Protein details for C4orf32 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N8J7-CD032_HUMAN
    Recommended name:
    Uncharacterized protein C4orf32
    Protein Accession:
    Q8N8J7
    Secondary Accessions:
    • Q49A91
    • Q4W5C7
    • Q8TBF9

    Protein attributes for C4orf32 Gene

    Size:
    132 amino acids
    Molecular mass:
    14653 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C4orf32 Gene

Proteomics data for C4orf32 Gene at MOPED

Post-translational modifications for C4orf32 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C4orf32 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C4orf32 Gene

Domains & Families for C4orf32 Gene

Protein Domains for C4orf32 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C4orf32: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C4orf32 Gene

Function for C4orf32 Gene

genes like me logo Genes that share phenotypes with C4orf32: view

Animal Model Products

CRISPR Products

miRNA for C4orf32 Gene

miRTarBase miRNAs that target C4orf32

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for C4orf32 Gene

Localization for C4orf32 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C4orf32 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for C4orf32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C4orf32: view

No data available for Subcellular locations from COMPARTMENTS for C4orf32 Gene

Pathways & Interactions for C4orf32 Gene

SuperPathways for C4orf32 Gene

No Data Available

Interacting Proteins for C4orf32 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000310182%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000385269%0d%0a
Selected Interacting proteins: ENSP00000310182 for C4orf32 Gene via STRING

Gene Ontology (GO) - Biological Process for C4orf32 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C4orf32 Gene

Drugs & Compounds for C4orf32 Gene

No Compound Related Data Available

Transcripts for C4orf32 Gene

mRNA/cDNA for C4orf32 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(59) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C4orf32 Gene

Chromosome 4 open reading frame 32:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C4orf32 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b
SP1:
SP2: -

Relevant External Links for C4orf32 Gene

GeneLoc Exon Structure for
C4orf32
ECgene alternative splicing isoforms for
C4orf32

Expression for C4orf32 Gene

mRNA expression in normal human tissues for C4orf32 Gene

mRNA differential expression in normal tissues according to GTEx for C4orf32 Gene

This gene is overexpressed in Adipose - Visceral (Omentum) (x5.3) and Adipose - Subcutaneous (x4.4).

Protein differential expression in normal tissues from HIPED for C4orf32 Gene

This gene is overexpressed in Bone (37.1), Adrenal (9.9), and Testis (7.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for C4orf32 Gene



SOURCE GeneReport for Unigene cluster for C4orf32 Gene Hs.23439

genes like me logo Genes that share expression patterns with C4orf32: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C4orf32 Gene

Orthologs for C4orf32 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C4orf32 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C6H4orf32 35
  • 87.88 (n)
  • 85.61 (a)
C6H4orf32 36
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C32H4orf32 35
  • 90.99 (n)
  • 90.09 (a)
C4orf32 36
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 5730508B09Rik 35
  • 87.4 (n)
  • 81.89 (a)
5730508B09Rik 16
5730508B09Rik 36
  • 79 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C4H4orf32 35
  • 98.99 (n)
  • 98.48 (a)
C4H4ORF32 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC691931 35
  • 85.68 (n)
  • 80.47 (a)
oppossum
(Monodelphis domestica)
Mammalia C4orf32 36
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C4orf32 36
  • 62 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C4orf32 36
  • 77 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c4orf32 35
  • 67.04 (n)
  • 65.17 (a)
Str.10017 35
zebrafish
(Danio rerio)
Actinopterygii zgc:113201 35
  • 50.29 (n)
  • 50 (a)
C13H4orf32 36
  • 42 (a)
OneToOne
Species with no ortholog for C4orf32:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C4orf32 Gene

ENSEMBL:
Gene Tree for C4orf32 (if available)
TreeFam:
Gene Tree for C4orf32 (if available)

Paralogs for C4orf32 Gene

No data available for Paralogs for C4orf32 Gene

Variants for C4orf32 Gene

Sequence variations from dbSNP and Humsavar for C4orf32 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
VAR_032150 -

Variation tolerance for C4orf32 Gene

Residual Variation Intolerance Score: 64.78% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.90; 18.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C4orf32 Gene

HapMap Linkage Disequilibrium report
C4orf32

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C4orf32 Gene

Disorders for C4orf32 Gene

Relevant External Links for C4orf32

Human Genome Epidemiology (HuGE) Navigator
C4orf32
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C4orf32
genes like me logo Genes that share disorders with C4orf32: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C4orf32 Gene

Publications for C4orf32 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. Association study of 25 type 2 diabetes related Loci with measures of obesity in Indian sib pairs. (PMID: 23349771) Gupta V. … Chandak G.R. (PLoS ONE 2013) 67
  4. A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts. (PMID: 20332099) Kalsi G. … Riley B.P. (Hum. Mol. Genet. 2010) 67
  5. Joint effects of common genetic variants on the risk for type 2 diabetes in U.S. men and women of European ancestry. (PMID: 19380854) Cornelis M.C. … Hu F.B. (Ann. Intern. Med. 2009) 67

Products for C4orf32 Gene

Sources for C4orf32 Gene

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