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Aliases for C4orf27 Gene

Aliases for C4orf27 Gene

  • Chromosome 4 Open Reading Frame 27 2 3

External Ids for C4orf27 Gene

Previous GeneCards Identifiers for C4orf27 Gene

  • GC04M170887
  • GC04M170650
  • GC04M166405

Summaries for C4orf27 Gene

GeneCards Summary for C4orf27 Gene

C4orf27 (Chromosome 4 Open Reading Frame 27) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C4orf27 Gene

Genomics for C4orf27 Gene

Regulatory Elements for C4orf27 Gene

Genomic Location for C4orf27 Gene

169,729,465 bp from pter
169,757,953 bp from pter
28,489 bases
Minus strand

Genomic View for C4orf27 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C4orf27 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C4orf27 Gene

Proteins for C4orf27 Gene

  • Protein details for C4orf27 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UPF0609 protein C4orf27
    Protein Accession:
    Secondary Accessions:

    Protein attributes for C4orf27 Gene

    346 amino acids
    Molecular mass:
    39436 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C4orf27 Gene

Proteomics data for C4orf27 Gene at MOPED

Post-translational modifications for C4orf27 Gene

  • Ubiquitination at Lys253
  • Modification sites at PhosphoSitePlus

Other Protein References for C4orf27 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for C4orf27

No data available for DME Specific Peptides for C4orf27 Gene

Domains for C4orf27 Gene

Protein Domains for C4orf27 Gene


Suggested Antigen Peptide Sequences for C4orf27 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q9NWY4
  • Belongs to the UPF0609 family.
genes like me logo Genes that share domains with C4orf27: view

No data available for Gene Families for C4orf27 Gene

Function for C4orf27 Gene

Phenotypes for C4orf27 Gene

genes like me logo Genes that share phenotypes with C4orf27: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C4orf27

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C4orf27 Gene

Localization for C4orf27 Gene

Subcellular locations from

Jensen Localization Image for C4orf27 Gene COMPARTMENTS Subcellular localization image for C4orf27 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for C4orf27 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
genes like me logo Genes that share ontologies with C4orf27: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C4orf27 Gene

Pathways for C4orf27 Gene

SuperPathways for C4orf27 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C4orf27 Gene


No data available for Pathways by source for C4orf27 Gene

Transcripts for C4orf27 Gene

mRNA/cDNA for C4orf27 Gene

(3) Additional mRNA sequences :
(121) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C4orf27 Gene

Chromosome 4 open reading frame 27:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C4orf27

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C4orf27 Gene

No ASD Table

Relevant External Links for C4orf27 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C4orf27 Gene

mRNA expression in normal human tissues for C4orf27 Gene

Protein differential expression in normal tissues for C4orf27 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (11.2) and Monocytes (7.2).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for C4orf27 Gene

SOURCE GeneReport for Unigene cluster for C4orf27 Gene Hs.406756

genes like me logo Genes that share expressions with C4orf27: view

Expression partners for C4orf27 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C4orf27 Gene

Orthologs for C4orf27 Gene

This gene was present in the common ancestor of animals.

Orthologs for C4orf27 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C8H4orf27 35
  • 86.22 (n)
  • 85.55 (a)
C4orf27 36
  • 86 (a)
(Canis familiaris)
Mammalia C25H4orf27 35
  • 92.73 (n)
  • 93.64 (a)
C4ORF27 36
  • 93 (a)
(Mus musculus)
Mammalia 2700029M09Rik 35
  • 90.06 (n)
  • 89.76 (a)
2700029M09Rik 16
2700029M09Rik 36
  • 89 (a)
(Pan troglodytes)
Mammalia C4H4orf27 35
  • 99.33 (n)
  • 98.84 (a)
C4orf27 36
  • 99 (a)
(Rattus norvegicus)
Mammalia RGD1311747 35
  • 87.95 (n)
  • 88.25 (a)
(Monodelphis domestica)
Mammalia C4orf27 36
  • 75 (a)
(Ornithorhynchus anatinus)
Mammalia C4orf27 36
  • 84 (a)
(Gallus gallus)
Aves C4H4ORF27 35
  • 74.57 (n)
  • 75.99 (a)
C4orf27 36
  • 74 (a)
(Anolis carolinensis)
Reptilia C4orf27 36
  • 78 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100488348 35
  • 69.4 (n)
  • 68.09 (a)
(Danio rerio)
Actinopterygii wufb44b08 35
zgc:101819 35
  • 64.95 (n)
  • 64.85 (a)
C1H4orf27 36
  • 63 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010317 35
  • 47.68 (n)
  • 37.22 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG1218 35
  • 47.03 (n)
  • 39.04 (a)
CG1218 36
  • 27 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.13723 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 44 (a)
Species with no ortholog for C4orf27:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C4orf27 Gene

Gene Tree for C4orf27 (if available)
Gene Tree for C4orf27 (if available)

Paralogs for C4orf27 Gene Pseudogenes for C4orf27 Gene

genes like me logo Genes that share paralogs with C4orf27: view

No data available for Paralogs for C4orf27 Gene

Variants for C4orf27 Gene

Sequence variations from dbSNP and Humsavar for C4orf27 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs1047642 - 169,742,084(-) ACTTA(A/G)AGAAA missense, reference
rs1047673 -- 169,731,827(-) GATGA(G/T)GAGAG reference, missense
rs1047706 - 169,729,626(-) GAGGA(G/T)CATCT reference, missense
rs1047716 -- 169,729,608(-) AGAAG(A/T)CAAGA missense, reference
rs1047719 -- 169,729,607(-) GAAGT(A/C)AAGAG missense, reference

Structural Variations from Database of Genomic Variants (DGV) for C4orf27 Gene

Variant ID Type Subtype PubMed ID
esv272640 CNV Insertion 20981092

Relevant External Links for C4orf27 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C4orf27 Gene

Disorders for C4orf27 Gene

Relevant External Links for C4orf27

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for C4orf27 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for C4orf27 Gene

Publications for C4orf27 Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. From ORFeome to biology: a functional genomics pipeline. (PMID: 15489336) Wiemann S. … Poustka A. (Genome Res. 2004) 3
  4. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  5. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A. … Wiemann S. (Nucleic Acids Res. 2006) 3

Products for C4orf27 Gene

Sources for C4orf27 Gene

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