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Aliases for C4orf27 Gene

Aliases for C4orf27 Gene

  • Chromosome 4 Open Reading Frame 27 2 3

External Ids for C4orf27 Gene

Previous GeneCards Identifiers for C4orf27 Gene

  • GC04M170887
  • GC04M170650
  • GC04M166405

Summaries for C4orf27 Gene

GeneCards Summary for C4orf27 Gene

C4orf27 (Chromosome 4 Open Reading Frame 27) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C4orf27 Gene

Genomics for C4orf27 Gene

Regulatory Elements for C4orf27 Gene

Genomic Location for C4orf27 Gene

Start:
169,729,465 bp from pter
End:
169,757,953 bp from pter
Size:
28,489 bases
Orientation:
Minus strand

Genomic View for C4orf27 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C4orf27 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C4orf27 Gene

Proteins for C4orf27 Gene

  • Protein details for C4orf27 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NWY4-CD027_HUMAN
    Recommended name:
    UPF0609 protein C4orf27
    Protein Accession:
    Q9NWY4
    Secondary Accessions:

    Protein attributes for C4orf27 Gene

    Size:
    346 amino acids
    Molecular mass:
    39436 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C4orf27 Gene

Proteomics data for C4orf27 Gene at MOPED

Post-translational modifications for C4orf27 Gene

  • Ubiquitination at Lys253
  • Modification sites at PhosphoSitePlus

Other Protein References for C4orf27 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C4orf27 Gene

Domains for C4orf27 Gene

Protein Domains for C4orf27 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C4orf27 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9NWY4

UniProtKB/Swiss-Prot:

CD027_HUMAN :
  • Q9NWY4
Family:
  • Belongs to the UPF0609 family.
genes like me logo Genes that share domains with C4orf27: view

No data available for Gene Families for C4orf27 Gene

Function for C4orf27 Gene

Phenotypes for C4orf27 Gene

genes like me logo Genes that share phenotypes with C4orf27: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C4orf27 Gene

Localization for C4orf27 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C4orf27 Gene COMPARTMENTS Subcellular localization image for C4orf27 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for C4orf27 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
genes like me logo Genes that share ontologies with C4orf27: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C4orf27 Gene

Pathways for C4orf27 Gene

SuperPathways for C4orf27 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C4orf27 Gene

None

No data available for Pathways by source for C4orf27 Gene

Transcripts for C4orf27 Gene

mRNA/cDNA for C4orf27 Gene

(121) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C4orf27 Gene

Chromosome 4 open reading frame 27:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C4orf27 Gene

No ASD Table

Relevant External Links for C4orf27 Gene

GeneLoc Exon Structure for
C4orf27
ECgene alternative splicing isoforms for
C4orf27

Expression for C4orf27 Gene

mRNA expression in normal human tissues for C4orf27 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for C4orf27 Gene

SOURCE GeneReport for Unigene cluster for C4orf27 Gene Hs.406756

genes like me logo Genes that share expressions with C4orf27: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C4orf27 Gene

Orthologs for C4orf27 Gene

This gene was present in the common ancestor of animals.

Orthologs for C4orf27 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C4H4orf27 35
  • 99.33 (n)
  • 98.84 (a)
C4orf27 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C4orf27 36
  • 86 (a)
OneToOne
C8H4orf27 35
  • 86.22 (n)
  • 85.55 (a)
dog
(Canis familiaris)
Mammalia C25H4orf27 35
  • 92.73 (n)
  • 93.64 (a)
C4ORF27 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2700029M09Rik 35
  • 90.06 (n)
  • 89.76 (a)
2700029M09Rik 16
2700029M09Rik 36
  • 89 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C4orf27 36
  • 75 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C4orf27 36
  • 84 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1311747 35
  • 87.95 (n)
  • 88.25 (a)
chicken
(Gallus gallus)
Aves C4H4ORF27 35
  • 74.57 (n)
  • 75.99 (a)
C4orf27 36
  • 74 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C4orf27 36
  • 78 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100488348 35
  • 69.4 (n)
  • 68.09 (a)
zebrafish
(Danio rerio)
Actinopterygii C1H4orf27 36
  • 63 (a)
OneToOne
wufb44b08 35
zgc:101819 35
  • 64.95 (n)
  • 64.85 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010317 35
  • 47.68 (n)
  • 37.22 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG1218 35
  • 47.03 (n)
  • 39.04 (a)
CG1218 36
  • 27 (a)
OneToOne
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.13723 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 44 (a)
OneToOne
Species with no ortholog for C4orf27:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C4orf27 Gene

ENSEMBL:
Gene Tree for C4orf27 (if available)
TreeFam:
Gene Tree for C4orf27 (if available)

Paralogs for C4orf27 Gene

Pseudogenes.org Pseudogenes for C4orf27 Gene

genes like me logo Genes that share paralogs with C4orf27: view

No data available for Paralogs for C4orf27 Gene

Variants for C4orf27 Gene

Sequence variations from dbSNP and Humsavar for C4orf27 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs1047642 - 169,742,084(-) ACTTA(A/G)AGAAA missense, reference
rs1047673 -- 169,731,827(-) GATGA(G/T)GAGAG reference, missense
rs1047706 - 169,729,626(-) GAGGA(G/T)CATCT reference, missense
rs1047716 -- 169,729,608(-) AGAAG(A/T)CAAGA missense, reference
rs1047719 -- 169,729,607(-) GAAGT(A/C)AAGAG missense, reference

Structural Variations from Database of Genomic Variants (DGV) for C4orf27 Gene

Variant ID Type Subtype PubMed ID
esv272640 CNV Insertion 20981092

Relevant External Links for C4orf27 Gene

HapMap Linkage Disequilibrium report
C4orf27

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C4orf27 Gene

Disorders for C4orf27 Gene

Relevant External Links for C4orf27

Genetic Association Database (GAD)
C4orf27
Human Genome Epidemiology (HuGE) Navigator
C4orf27
genes like me logo Genes that share disorders with C4orf27: view

No data available for UniProtKB/Swiss-Prot for C4orf27 Gene

Publications for C4orf27 Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. From ORFeome to biology: a functional genomics pipeline. (PMID: 15489336) Wiemann S. … Poustka A. (Genome Res. 2004) 3
  4. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  5. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A. … Wiemann S. (Nucleic Acids Res. 2006) 3

Products for C4orf27 Gene

Sources for C4orf27 Gene

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