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Aliases for C4orf19 Gene

Aliases for C4orf19 Gene

  • Chromosome 4 Open Reading Frame 19 2 3 5

External Ids for C4orf19 Gene

Previous GeneCards Identifiers for C4orf19 Gene

  • GC04P037131
  • GC04P036779

Summaries for C4orf19 Gene

GeneCards Summary for C4orf19 Gene

C4orf19 (Chromosome 4 Open Reading Frame 19) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C4orf19 Gene

Genomics for C4orf19 Gene

Regulatory Elements for C4orf19 Gene

Enhancers for C4orf19 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C4orf19 on UCSC Golden Path with GeneCards custom track

Promoters for C4orf19 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C4orf19 on UCSC Golden Path with GeneCards custom track

Genomic Location for C4orf19 Gene

37,453,454 bp from pter
37,623,495 bp from pter
170,042 bases
Plus strand

Genomic View for C4orf19 Gene

Genes around C4orf19 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C4orf19 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C4orf19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C4orf19 Gene

Proteins for C4orf19 Gene

  • Protein details for C4orf19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C4orf19
    Protein Accession:
    Secondary Accessions:
    • Q9NV03

    Protein attributes for C4orf19 Gene

    314 amino acids
    Molecular mass:
    33742 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C4orf19 Gene

Proteomics data for C4orf19 Gene at MOPED

Post-translational modifications for C4orf19 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C4orf19 Gene

No data available for DME Specific Peptides for C4orf19 Gene

Domains & Families for C4orf19 Gene

Protein Domains for C4orf19 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C4orf19: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C4orf19 Gene

Function for C4orf19 Gene

Phenotypes for C4orf19 Gene

genes like me logo Genes that share phenotypes with C4orf19: view

Animal Model Products

CRISPR Products

miRNA for C4orf19 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C4orf19 Gene

Localization for C4orf19 Gene

Subcellular locations from

Jensen Localization Image for C4orf19 Gene COMPARTMENTS Subcellular localization image for C4orf19 gene
Compartment Confidence
nucleus 5
cytosol 1

Gene Ontology (GO) - Cellular Components for C4orf19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with C4orf19: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C4orf19 Gene

Pathways & Interactions for C4orf19 Gene

SuperPathways for C4orf19 Gene

No Data Available

Interacting Proteins for C4orf19 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000284437 Q8IY42-CD019_HUMAN for C4orf19 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for C4orf19 Gene


No data available for Pathways by source and SIGNOR curated interactions for C4orf19 Gene

Drugs & Compounds for C4orf19 Gene

No Compound Related Data Available

Transcripts for C4orf19 Gene

Unigene Clusters for C4orf19 Gene

Chromosome 4 open reading frame 19:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C4orf19 Gene

No ASD Table

Relevant External Links for C4orf19 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C4orf19 Gene

mRNA expression in normal human tissues for C4orf19 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C4orf19 Gene

This gene is overexpressed in Pancreas (x7.1) and Liver (x4.5).

Protein differential expression in normal tissues from HIPED for C4orf19 Gene

This gene is overexpressed in Heart (67.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C4orf19 Gene

SOURCE GeneReport for Unigene cluster for C4orf19 Gene Hs.107527

genes like me logo Genes that share expression patterns with C4orf19: view

Protein tissue co-expression partners for C4orf19 Gene

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for C4orf19 Gene

Orthologs for C4orf19 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C4orf19 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C6H4orf19 35
  • 73.04 (n)
  • 60.51 (a)
C4orf19 36
  • 59 (a)
(Mus musculus)
Mammalia 0610040J01Rik 35
  • 72.06 (n)
  • 60.07 (a)
0610040J01Rik 16
0610040J01Rik 36
  • 58 (a)
(Pan troglodytes)
Mammalia C4H4orf19 35
  • 99.58 (n)
  • 99.36 (a)
C4orf19 36
  • 99 (a)
(Rattus norvegicus)
Mammalia LOC498368 35
  • 70.74 (n)
  • 58.42 (a)
(Canis familiaris)
Mammalia C4orf19 36
  • 37 (a)
(Monodelphis domestica)
Mammalia C4orf19 36
  • 40 (a)
(Gallus gallus)
Aves C4orf19 36
  • 32 (a)
(Anolis carolinensis)
Reptilia C4orf19 36
  • 22 (a)
Species with no ortholog for C4orf19:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C4orf19 Gene

Gene Tree for C4orf19 (if available)
Gene Tree for C4orf19 (if available)

Paralogs for C4orf19 Gene

(5) SIMAP similar genes for C4orf19 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with C4orf19: view

No data available for Paralogs for C4orf19 Gene

Variants for C4orf19 Gene

Sequence variations from dbSNP and Humsavar for C4orf19 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
VAR_032118 -
VAR_032119 -
VAR_050770 -
rs871173 -- 37,523,565(+) tgctc(C/T)ACCTC intron-variant
rs872047 -- 37,524,308(-) aaggc(C/G)caacc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C4orf19 Gene

Variant ID Type Subtype PubMed ID
esv2656828 CNV Deletion 23128226
nsv829909 CNV Loss 17160897
esv21522 CNV Loss 19812545
esv2727430 CNV Deletion 23290073
esv1036244 CNV Deletion 17803354
nsv521553 CNV Loss 19592680
nsv878934 CNV Gain 21882294
esv2254243 CNV Deletion 18987734
nsv822534 CNV Loss 20364138
esv999359 CNV Deletion 20482838
esv2677154 CNV Deletion 23128226
esv2727431 CNV Deletion 23290073
nsv4303 CNV Insertion 18451855
esv2674540 CNV Deletion 23128226

Variation tolerance for C4orf19 Gene

Residual Variation Intolerance Score: 88% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.23; 62.26% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for C4orf19 Gene

Disorders for C4orf19 Gene

Relevant External Links for C4orf19

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C4orf19 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C4orf19 Gene

Publications for C4orf19 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3

Products for C4orf19 Gene

Sources for C4orf19 Gene