C4BPB Gene
protein-coding GIFtS: 55
GCID: GC01P207262
|
|
complement component 4 binding protein, beta(Previous names: complement component 4-binding protein, beta )
(Previous symbol: C4BP)
| |
Aliases
for C4BPB gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Complement Component 4 Binding Protein, Beta1 2 | | C4BP1 2 | | Complement Component 4-Binding Protein, Beta1 | | C4b-Binding Protein Beta Chain2 |
Export aliases for C4BPB gene to outside databasesPrevious GC identifers: GC01P205922 GC01P202972 GC01P203905 GC01P204346 GC01P203650 GC01P205328 GC01P177959 |
Summaries
for C4BPB gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for C4BPB:
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensusrepeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with sevenidentical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controlsactivation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in thecoagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein thatserves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent toeach other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing givesrise to multiple transcript variants. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: C4BPB_HUMAN, P20851Function: Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator(C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex(C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and withserum amyloid P component. The beta chain binds protein S
|
Genomic Views
for C4BPB gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_167186.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C4BPB gene promoter:
C/EBPbeta GATA-3 GATA-2 GATA-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for C4BPB
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C4BPB |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q32 Ensembl cytogenetic band: 1q32.2 HGNC cytogenetic band: 1q32C4BPB Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P207262: view genomic region
(about GC identifiers)
Start:
|
207,262,187 bp from pter |
End:
|
207,273,338 bp from pter |
Size:
|
11,152 bases |
Orientation:
|
plus strand |
|
Proteins
for C4BPB gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: C4BPB_HUMAN, P20851 (See
protein sequence)Recommended Name: C4b-binding protein beta chain precursor Size: 252 amino acids; 28357 Da
Subunit: Disulfide-linked complex of alpha and beta chains of 3 possible sorts: a 570 kDa complex of 7 alpha chains and1 beta chain, a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain. Thecentral body of the alpha chain homopolymer supports tentacles, each with the binding site for C4b at the end
Subcellular location: Secreted
Secondary accessions: A5JYP8 D3DT81 Q5VVR0 Q9BS25Alternative splicing: 2 isoforms: P20851-1 P20851-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for C4BPB: NX_P20851
C4BPB Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_000707.1 NP_001017364.1 NP_001017365.1 NP_001017366.1 NP_001017367.1
ENSEMBL proteins: ENSP00000356045 ENSP00000392237 ENSP00000243611 ENSP00000356043 ENSP00000375790 ENSP00000405649 Reactome Protein details: P20851
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
C4BPB for ontologies About GeneDecksing
C4BPB Antibody Products:
Assay Products for C4BPB: |
Protein
Domains /
Families
for C4BPB gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
C4BPB for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry P20851ProtoNet protein and cluster: P20851 1 Blocks protein family: IPB000436 Sushi domain/SCR domain/CCP module
UniProtKB/Swiss-Prot: C4BPB_HUMAN, P20851Similarity: Contains 3 Sushi (CCP/SCR) domains |
Function
for C4BPB gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: C4BPB_HUMAN, P20851Function: Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator(C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex(C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and withserum amyloid P component. The beta chain binds protein S Genatlas biochemistry entry for C4BPB:complement component 4,binding protein beta,45kDa,regulator of C3 convertase of classical pathway,see RCA@
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C4BPB (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C4BPB (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 5): C4BPB (NM_000716) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C4BPB | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C4BPB |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C4BPB |
|
Pathways & Interactions
for C4BPB gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Activation of C3 and C5 | | | 2 | Immune response_Classical complement pathway | | | 3 | Immune System | | | 4 | Immune response_Alternative complement pathway | | | 5 | FOXA1 transcription factor network | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for C4BPB
2  GeneGo (Thomson Reuters) Pathways for C4BPB
1  BioSystems Pathway for C4BPB
5/6 
Reactome Pathways for C4BPB (see all 6)
2 
Kegg Pathways (Kegg details for C4BPB):
C4BPB for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for C4BPB
STRING Interaction
Network Preview (showing 5 interactants - click image to see 10)
5/10 Interacting proteins for C4BPB (P208513 ENSP000002436114) via UniProtKB, MINT, STRING, and/or I2D (see all 10)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
C4BPB for ontologies About GeneDecksing
|
Drugs & Compounds
for C4BPB gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
C4BPB for compounds About GeneDecksing
 Browse Tocris compounds for C4BPB
6 Novoseek chemical compound relationships for C4BPB gene About this table
Search CenterWatch for drugs/clinical trials and news about C4BPB
|
Transcripts
for C4BPB gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C4BPB gene (5 alternative transcripts): NM_000716.3 NM_001017364.1 NM_001017365.1 NM_001017366.1 NM_001017367.1 Unigene Cluster for C4BPB: Complement component 4 binding protein, beta Hs.99886 [show with all ESTs]Unigene Representative Sequence: AK3151379 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000367078(uc001hfj.3 uc001hfi.3) ENST00000492730 ENST00000452902
ENST00000243611(uc001hfl.3 uc001hfm.3) ENST00000367076(uc001hfk.3 uc009xcd.3)
ENST00000469326 ENST00000470767 ENST00000391923 ENST00000451804(uc010pse.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C4BPB (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C4BPB (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 5): C4BPB (NM_000716) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C4BPB | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C4BPB |
Additional cDNA sequence: AK293379.1 AK315137.1 BC005378.1 L11245.1 M29964.1 9 DOTS entries: DT.456049 DT.91703213 DT.40131808 DT.91703225 DT.100741677 DT.91703220 DT.100741678 DT.101979475 DT.95122434 24/72 AceView cDNA sequences (see all 72): M29964 CD013942 CD013943 CB163639 BC005378 T41035 AA969142 BE545748 CR598788 BQ650658 CD013941 H78142 CR625432 BM987840 BG568220 AA779336 T40922 BG569580 T41007 BX362549 BG563617 NM_000716 BG616962 BG568230
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for C4BPB (see all 9) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | · | 7c |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | - | | - | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | - | | - | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | - | | - | | - | | | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | |
ECgene alternative splicing isoforms for C4BPB
|
Expression
for C4BPB gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C4BPB expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACAATGGAGG
About this image
See C4BPB Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C4BPB
SOURCE GeneReport for Unigene cluster: Hs.99886
SABiosciences Custom PCR Arrays for C4BPB
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C4BPB
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C4BPB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C4BPB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C4BPB | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C4BPB |
Orthologs
for C4BPB gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for C4BPB gene from 2/9 species (see all 9) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
zebrafish
(Danio rerio) |
Actinopterygii |
CABZ01035080.16 |
-- |
|
1 ↔ 1 |
Zv9_NA609(898-53002) |
worm
(Caenorhabditis elegans) |
Secernentea |
C54G4.46 |
Protein C54G4.4 |
3(a) |
1 ↔ 1 |
I(7996723-8003174) |
ENSEMBL Gene Tree for C4BPB (if available)
TreeFam Gene Tree for C4BPB (if available) |
Paralogs
for C4BPB gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for C4BPB gene
- ENSG000002442552 CFB2 C22
18/36 SIMAP similar genes for C4BPB using alignment to 3 protein entries: C4BPB_HUMAN (see all proteins)
(see all similar genes):ATL2 ZNF564 COQ5 SH2B3 SUMO1 UBXN4
FAM175A FLJ00047 SNRPF GBGT1 PFKFB3 RQCD1
NCKAP1L GALK2 CASC4 HC6 MST132 ZRSR2
C4BPB for paralogs About GeneDecksing
|
Genomic Variants
for C4BPB gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C4BPB (207262187 - 207273338 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C4BPB: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C4BPB |
|
Disorders
/ Diseases
for C4BPB gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C4BPB for disorders About GeneDecksing
OMIM gene information: 120831
OMIM disorders: --
20  diseases for C4BPB: About MalaCardshemolytic-uremic syndrome atypical hemolytic-uremic syndrome age related macular degeneration critical limb ischemia
non-hodgkin lymphoma macular degeneration haemophilus influenzae hodgkin's lymphoma
thrombosis protein s deficiency influenza hepatitis b
ischemia pertussis alzheimer's disease meningioma
hepatitis pneumonia leukemia venous thrombosis
1 disease from the University of Copenhagen DISEASES database for C4BPB:Protein S deficiency 4 Novoseek disease relationships for C4BPB gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| response acute phase |
29.5 |
6 |
7561114 (2), 8598458 (1) |
| inflammation |
3.06 |
2 |
19563958 (1), 12907438 (1) |
| necrosis |
0 |
2 |
19563958 (2) |
| thrombosis |
0 |
1 |
9169428 (1) |
Human Genome Epidemiology (HuGE) Navigator: C4BPB (9 documents)
Export disorders for C4BPB gene to outside databases
|
Publications
for C4BPB gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C4BPB gene, integrated from 9 sources (see all 90):
(articles sorted by number of sources associating them with C4BPB) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human C4b-binding protein beta-chain gene. (PubMed id 8325877)1, 2, 3, 9 Hillarp A....Dahlback B. (1993)
- Cloning of cDNA coding for the beta chain of human complement component C4b-binding protein: sequence homology with the alpha chain. (PubMed id 2300577)1, 2, 3 Hillarp A. and Dahlback B. (1990)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Isoforms of human C4b-binding protein. I. Molecular basis for the C4BP isoform pattern and its variations in human plasma. (PubMed id 7561113)1, 9 Sanchez-Corral P....Rodriguez de Cordoba S. (1995)
- Promoter region of the human gene coding for beta-chain of C4b binding protein. Hepatocyte nuclear factor-3 and nuclear factor-I/CTF transcription factors are required for efficient expression of C4BPB in HepG2 cells. (PubMed id 8598458)1, 9 Arenzana N. and Rodriguez de Cordoba S. (1996)
- C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation. (PubMed id 15967823)1, 9 Trouw L.A....Blom A.M. (2005)
- Vitamin K-dependent protein S localizing complement regulator C4b-binding protein to the surface of apoptotic cells. (PubMed id 12193728)1, 9 Webb J.H....Dahlback B. (2002)
- Functions of human complement inhibitor C4b-binding protein in relation to its structure. (PubMed id 15179322)1, 9 Blom A.M....Dahlback B. (2004)
|
External Searches for C4BPB gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C4BPB gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C4BPB gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C4BPB gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C4BPB | Pharmacogenomics, SNPs, Pathways | | SeattleSNPs | http://pga.gs.washington.edu/data/c4bpb/ |
|
| | |
About This Section
| Patent Information for C4BPB gene:
Search GeneIP for patents involving C4BPB
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C4BPB gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C4BPB | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C4BPB | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C4BPB | | | OriGene Protein Over-expression Lysate for C4BPB | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C4BPB | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C4BPB | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C4BPB | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C4BPB | | OriGene Custom Protein Services for C4BPB | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C4BPB | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C4BPB | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C4BPB | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C4BPB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C4BPB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C4BPB |
| |
 |  |  |  | |
| | | | Search Tocris compounds for C4BPB |
| |  |  |  |  | | | | | | Recombinant Protein for C4BPB |
|
 |
 |
 |
 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C4BPB |
|  |  |  | | | | Search ThermoFisher Antibodies for C4BPB |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C4BPB |
|
|
|
|
